Anti-inflammatory Therapeutics Market
By Drug Class;
Anti-Inflammatory Biologics, NSAIDs and OthersBy Application;
Autoimmune Diseases [Rheumatoid Arthritis, Psoriasis, Multiple Sclerosis, Crohn's Disease, Ulcerative Colitis and Others], Respiratory Conditions [COPD, Asthma] and OthersBy Route of Administration;
Oral, Injection, Topical and InhalationBy Distribution Channel;
Hospital Pharmacies, Retail Pharmacies and Online PharmaciesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Anti-Inflammatory Therapeutics Market Overview
Anti-Inflammatory Therapeutics Market (USD Million)
Anti-Inflammatory Therapeutics Market was valued at USD 83,185.41 million in the year 2024. The size of this market is expected to increase to USD 119,968.17 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 5.4%.
Anti-Inflammatory Therapeutics Market is witnessing rapid advancement due to the growing incidence of chronic inflammatory conditions like arthritis and autoimmune disorders. Approximately 52% of chronic pain prescriptions now include anti-inflammatory medications, underscoring their essential role in managing long-term health conditions.
Biologics Driving Targeted Treatment
A notable trend is the expanding use of biologic anti-inflammatory therapies, making up about 41% of current treatment regimens. These therapies are increasingly favored for their targeted action and lower side effect profiles, helping patients experience improved therapeutic results and better overall management of inflammation.
Rising Appeal of Non-Steroidal Options
The preference for non-steroidal anti-inflammatory drugs (NSAIDs) has grown significantly, with usage increasing by 34%. Their effectiveness in controlling pain without immunosuppressive risks makes them a preferred choice, especially for long-term treatment strategies where safety is a top concern.
Collaborative R&D Fueling Market Expansion
Industry players are expanding their pipelines through strategic collaborations, contributing to around 47% of development activity in this space. These partnerships are vital in accelerating research, reducing time to market, and ensuring the continuous introduction of innovative therapies for inflammation management.
Anti-inflammatory Therapeutics Market Key Takeaways
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Anti-inflammatory Therapeutics Market is evolving rapidly with the surge in chronic inflammatory disorders, autoimmune diseases, and age-related conditions. Rising awareness of personalized medicine and targeted biological therapies continues to transform global treatment approaches.
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Advancements in monoclonal antibodies, cytokine inhibitors, and JAK-STAT pathway blockers are reshaping the therapeutic landscape. These next-generation biologics provide enhanced efficacy, fewer side effects, and longer treatment durations.
Anti-inflammatory Therapeutics Market
*Market size in USD million
CAGR 5.4 %
Study Period 2025 - 2031 Base Year 2024 CAGR (%) 5.4 % Market Size (2024) USD 83,185.41 Million Market Size (2031) USD 119,968.17 Million Market Concentration Medium Report Pages 387 Major Players
- AbbVie, Inc.
- Merck & Co., Inc.
- Johnson & Johnson Services, Inc.
- Pfizer, Inc.
- Novartis AG
- GlaxoSmithKline plc.
- Amgen, Inc.
- F. Hoffmann-La Roche Ltd.
- AstraZeneca
- Sanofi
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Anti-inflammatory Therapeutics Market
Fragmented - Highly competitive market without dominant players
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Approximately 60% of global patients rely on NSAIDs and corticosteroids, yet safety concerns are accelerating the shift toward biologic and biosimilar therapies. The transition toward immunomodulatory mechanisms reflects a focus on precision inflammation control.
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The integration of AI-driven drug discovery and computational biology is significantly reducing R&D timelines. Pharmaceutical firms are leveraging machine learning models to predict molecular efficacy and improve clinical trial success rates.
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Strategic alliances among biotech innovators, pharma majors, and research institutes are expediting pipeline diversification. Around 48% of ongoing collaborations target autoimmune pathways such as rheumatoid arthritis and psoriasis.
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Rising demand in emerging economies is fueled by improved healthcare infrastructure, increased clinical access, and affordable biosimilars. Government efforts to enhance chronic disease management programs are bolstering treatment affordability.
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The growing focus on oral biologics and novel drug delivery systems is driving innovation in patient-centric therapy models. The shift toward non-invasive delivery and sustained-release formulations reflects a broader trend in therapeutic convenience.
Anti-Inflammatory Therapeutics Market Recent Developments
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In October 2023, Zydus Lifesciences initiated a Phase 2 clinical trial to evaluate the safety and efficacy of its anti-inflammatory therapy, ZYIL1, for amyotrophic lateral sclerosis (ALS). Approved by the CDSCO, the study aims to target the NLRP3 inflammasome pathway, reinforcing Zydus’ dedication to addressing unmet needs in neurodegenerative diseases.
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In July 2023, AbbVie announced the dosing of the first patient in its Phase 3 Step-Up HS study evaluating upadacitinib (RINVOQ) in adults and adolescents with moderate to severe hidradenitis suppurativa (HS). The study focuses on patients unresponsive to prior anti-TNF or other approved therapies, emphasizing AbbVie’s continued innovation in immunology research.
Anti-inflammatory Therapeutics Market Segment Analysis
In this report, the Anti-inflammatory Therapeutics Market has been segmented by Drug Class, Application, Route of Administration, Distribution Channel and Geography. Buyers prioritize efficacy–safety balance, steroid-sparing strategies and quality-of-life gains, while payers emphasize real-world adherence and total cost of care. Mix continues to shift toward biologic and advanced topical/inhaled options that demonstrate durable control with measurable % improvements in persistence and patient-reported outcomes.
Anti-inflammatory Therapeutics Market, Segmentation by Drug Class
The Drug Class axis contrasts anti-inflammatory biologics with broad-use NSAIDs and others, reflecting trade-offs in target specificity, onset and monitoring. Clinical adoption is reinforced by guideline endorsements, step-therapy rules and pharmacovigilance data, with treatment pathways showing high-single-digit % improvements in remission maintenance where tight-control protocols and digital follow-up are applied.
Anti-Inflammatory Biologics
Anti-inflammatory biologics drive premium growth through targeted cytokine/cell-signaling inhibition and steroid-sparing benefits. Care models leveraging treat-to-target, therapeutic drug monitoring and nurse-led education report adherence lifts by notable %, while payer contracts with outcomes clauses expand access in high-need cohorts.
NSAIDs
NSAIDs remain first-line for symptomatic control across musculoskeletal and acute flares with broad primary-care reach. Risk-minimization via GI protection, CV screening and renal monitoring improves appropriateness by measurable %, sustaining volume despite step-up to advanced agents in refractory disease.
Others
Others encompass corticosteroids, DMARDs and adjunctive agents used for induction, bridging or combination strategies. Protocols that taper steroids and lock in maintenance reduce cumulative exposure by meaningful %, supporting long-term safety stewardship across indications.
Anti-inflammatory Therapeutics Market, Segmentation by Application
The Application axis links disease biology to route and class selection, spanning autoimmune diseases, respiratory conditions and others. Centers adopting multidisciplinary clinics, tight-control algorithms and remote symptom tracking achieve high-single-digit % gains in remission or low-activity states, while standardized flare protocols compress time-to-response by measurable.
Autoimmune Diseases
Autoimmune diseases anchor biologic utilization with structured escalation from conventional agents to targeted therapies. Imaging, biomarkers and minimal disease activity metrics guide adjustments, lifting sustained response rates by notable % when combined with adherence coaching and vaccination stewardship.
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Rheumatoid Arthritis
Programs using treat-to-target, early initiation and shared decision-making deliver mid-single-digit % improvements in functional scores. Co-management of CV risk and infection prophylaxis enhances safety while sustaining remission maintenance.
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Psoriasis
Selective cytokine blockade achieves high response durability with measurable % PASI-level gains. Dermatology–rheumatology collaboration improves screening for psoriatic arthritis, reducing diagnostic delay by notable %.
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Multiple Sclerosis
Disease-modifying strategies prioritize relapse reduction and disability slowing. Monitoring via MRI and adherence apps improves persistence by meaningful %, supporting long-term neurological outcomes.
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Crohn's Disease
Mucosal healing objectives and therapeutic drug monitoring drive dose optimization with measurable % reductions in steroid exposure. Multidisciplinary IBD units raise remission durability and surgery avoidance.
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Ulcerative Colitis
Algorithms align to endoscopic targets and rapid escalation during flares. Home support and infusion-center capacity boosts on-schedule dosing by notable %, stabilizing quality-of-life metrics.
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Others
Includes immune-mediated conditions managed with tailored biologic/DMARD combinations. Real-world registries enhance comparative effectiveness insights and drive protocol refinement by measurable %.
Respiratory Conditions
Respiratory conditions focus on exacerbation prevention and steroid minimization, with inhaled and biologic options tuned to phenotypes and biomarkers. Integrated action plans and spirometry-linked feedback improve control days by high-single-digit % and reduce urgent care utilization.
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COPD
Triple-therapy optimization and exacerbation risk targeting drive reductions in flare frequency by measurable %. Pulmonary rehab and adherence nudges strengthen symptom stability and therapy continuity.
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Asthma
Biologic add-ons for severe phenotypes, plus SMART regimens, raise well-controlled days by notable %. Digital inhaler feedback and education programs lift correct-use rates and reduce rescue reliance.
Others
Others capture dermatologic, gastrointestinal and musculoskeletal inflammatory states outside core groups. Pathway-aligned care bundles with lifestyle counseling increase remission-like control by meaningful %, supporting step-down from systemic steroids.
Anti-inflammatory Therapeutics Market, Segmentation by Route of Administration
The Route of Administration axis spans oral, injection, topical and inhalation approaches, matching disease location and adherence needs. Home-care enablement, self-injection training and device usability drive persistence gains by measurable %, while specialty pharmacy support raises on-time dosing across chronic regimens.
Oral
Oral routes maximize convenience and rapid access in primary and specialty care. Medication synchronization and safety monitoring lift adherence by notable %, sustaining symptom control where mild-to-moderate disease predominates.
Injection
Injection includes office- and home-administered biologics with long dosing intervals. Nurse coaching, device choice and cold-chain reliability improve persistence by meaningful %, reducing flare-related interruptions.
Topical
Topical formulations target localized skin and mucosal inflammation with minimized systemic exposure. Patient training on application and tapering reduces adverse effects by measurable %, supporting maintenance strategies.
Inhalation
Inhalation delivers airway-focused therapy with device technique central to outcomes. Digital counters and feedback tools raise correct-use rates by notable %, improving control and reducing rescue use.
Anti-inflammatory Therapeutics Market, Segmentation by Distribution Channel
The Distribution Channel axis calibrates access, reimbursement and patient support across hospital, retail and online pharmacies. Programs combining benefits navigation, refill reminders and pharmacist counseling elevate persistence by high-single-digit %, while cold-chain and inventory analytics stabilize supply during peaks.
Hospital Pharmacies
Hospital pharmacies manage induction, biologic infusion and discharge coordination. Embedded clinical pathways and prior-auth teams cut time-to-therapy by measurable %, improving continuity post-discharge.
Retail Pharmacies
Retail pharmacies sustain chronic dispensing with MTM services, safety screens and device coaching. Synchronization and outreach increase proportion-of-days-covered by notable %, supporting steady control.
Online Pharmacies
Online pharmacies expand reach via home delivery, auto-refill and virtual counseling. Digital adherence nudges improve on-time medication possession by meaningful, particularly for mobility-limited patients.
Anti-inflammatory Therapeutics Market, Segmentation by Geography
In this report, the Anti-inflammatory Therapeutics Market has been segmented by Geography into five regions: North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
North America
North America leads on guideline-driven treat-to-target, specialty-pharmacy infrastructure and outcomes-based contracts. Integrated registries and remote monitoring lift persistence by notable %, supporting durable steroid-sparing management.
Europe
Europe emphasizes HTA alignment, biosimilar adoption and standardized care bundles. Cross-border registries and adherence programs raise remission stability by measurable %, improving access and affordability.
Asia Pacific
Asia Pacific shows fastest uptake with expanding specialty centers and e-pharmacy reach. Patient education and risk-minimization protocols improve control metrics by meaningful %, accelerating step-up to targeted therapies.
Middle East & Africa
Middle East & Africa adoption concentrates in tertiary hubs with growing biologic access. Clinician training and hub-and-spoke models raise on-schedule dosing by notable %, extending advanced care beyond capitals.
Latin America
Latin America advances via public procurement, patient-support programs and biosimilar competition. Pharmacy partnerships and tele-follow-ups increase refill timeliness by measurable %, strengthening continuity across chronic regimens.
Anti-Inflammatory Therapeutics Market Forces
This report provides an in depth analysis of various factors that impact the dynamics of Anti-Inflammatory Therapeutics Market. These factors include; Market Drivers, Restraints and Opportunities.
Drivers:
- Aging Population
- Biologic Innovations
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Rising Awareness - There has been a notable shift in societal attitudes towards health, with individuals becoming more proactive in managing their well-being. Patients are increasingly informed about the signs, symptoms, and consequences of inflammatory conditions, prompting them to seek timely medical intervention. Moreover, advancements in medical research and the dissemination of scientific knowledge through publications and conferences contribute to a deeper understanding of inflammatory diseases among healthcare providers and patients alike.
The advent of social media and online health communities has facilitated the sharing of personal experiences and treatment outcomes, fostering a sense of solidarity among individuals affected by inflammatory conditions. This digital interconnectedness has empowered patients to advocate for better access to treatment options and participate actively in shared decision-making with their healthcare providers.
Governmental and non-governmental organizations are playing an instrumental role in raising awareness about inflammatory diseases through public health campaigns, educational initiatives, and policy advocacy. These efforts aim to destigmatize inflammatory conditions, improve early detection rates, and promote adherence to treatment regimens.
Restraints:
- Side Effects
- Cost Constraints
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Patent Expiry - For pharmaceutical companies, patent expirations translate into the loss of market exclusivity and a subsequent decline in revenue as cheaper generic alternatives flood the market. This erosion of market share can be particularly acute for blockbuster anti-inflammatory drugs, which often generate substantial profits. Generic competition drives down drug prices, impacting profitability and potentially leading to reduced investments in research and development for new therapies.
Patent expiry may result in a decrease in brand loyalty among patients and healthcare providers, as generic versions are often perceived as equally effective but more cost-effective alternatives. This can further erode sales of originator drugs, exacerbating the revenue decline for pharmaceutical companies.
The impact of patent expiry extends beyond individual companies to the broader anti-inflammatory therapeutics market. While generic competition can lower treatment costs and improve accessibility for patients, it also poses challenges in terms of maintaining innovation and investment in new drug development. The decreased revenue from originator drugs may deter companies from investing in research and development for novel anti-inflammatory therapies, potentially stifling innovation in the long term.
Opportunities:
- Emerging Markets
- Personalized Medicine
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New Drug Approvals - One of the key areas of opportunity lies in addressing unmet medical needs, particularly in severe and refractory inflammatory conditions. New drug approvals enable the expansion of treatment options for patients who may not respond adequately to existing therapies or who experience intolerable side effects. Additionally, the approval of biosimilars—biologic drugs that are highly similar to existing biologics—offers cost-effective alternatives, increasing accessibility to life-changing treatments for a broader patient population.
Advancements in drug discovery and development technologies, such as high-throughput screening and computational modeling, facilitate the identification and optimization of novel anti-inflammatory compounds. This accelerates the pace of new drug approvals, shortening the timeline from preclinical research to clinical application. Regulatory agencies, recognizing the urgent need for innovative therapies, are implementing expedited review pathways and providing incentives for the development of orphan drugs targeting rare inflammatory conditions.
Strategic collaborations between pharmaceutical companies, academic institutions, and research organizations are also driving new drug approvals. These partnerships leverage complementary expertise and resources, fostering innovation and accelerating the translation of scientific discoveries into clinically viable treatments. Moreover, increased investment in precision medicine approaches, including biomarker-driven drug development and patient stratification strategies, enhances the likelihood of successful new drug approvals by enabling more targeted and personalized therapeutic interventions.
Anti-inflammatory Therapeutics Market Competitive Landscape Analysis
Anti-inflammatory Therapeutics Market is defined by competition among pharmaceutical companies, biotech firms, and regional distributors. Companies adopt strategies such as mergers, partnerships, and collaboration to enhance efficacy, safety, and targeted delivery. With nearly 60% of share concentrated among leading players, continuous innovation in biologics, small molecules, and combination therapies drives steady growth across autoimmune, chronic pain, and inflammatory disorder treatments.
Market Structure and Concentration
The industry demonstrates moderate concentration, with about 55% of revenues controlled by multinational anti-inflammatory therapeutic manufacturers. Regional producers contribute to expansion through niche formulations and cost-effective therapies. This combination of consolidated leadership and fragmented innovation shapes competitive strategies, ensuring consistent growth in anti-inflammatory therapeutic adoption.
Brand and Channel Strategies
Leading firms strengthen their brands through partnerships with hospitals, collaborations with specialty clinics, and direct contracts with healthcare providers. Nearly 60% of adoption occurs via hospital pharmacies and specialty distributors, while online healthcare platforms support channel expansion. Effective strategies emphasize efficacy, safety, and patient adherence, reinforcing sustainable growth in the market.
Innovation Drivers and Technological Advancements
Ongoing innovation focuses on targeted delivery mechanisms, advanced biologics, and combination therapies. Around 45% of R&D investments target technological advancements that improve treatment efficacy, reduce side effects, and enhance patient compliance. Strategic collaboration between manufacturers and research institutions drives strategies, enabling measurable growth in anti-inflammatory therapeutic technology.
Regional Momentum and Expansion
North America accounts for nearly 40% of demand, driven by advanced healthcare infrastructure and high disease prevalence. Europe demonstrates steady growth with adoption in hospitals and specialty clinics, while Asia-Pacific shows rapid expansion surpassing 25% due to increasing chronic inflammatory conditions and access to advanced therapies. Regional strategies enhance market penetration and competitive positioning.
Future Outlook
The market is projected to sustain robust growth as demand for safe, effective, and targeted anti-inflammatory therapeutics rises. Stronger partnerships and mergers will reshape competitive landscapes, while continuous innovation ensures improved efficacy, patient adherence, and therapeutic outcomes. The future outlook highlights broad expansion supported by healthcare growth and technological advancements.
Key players in Anti-Inflammatory Therapeutics Market include:
- AbbVie
- Pfizer
- Johnson & Johnson
- Novartis
- Merck & Co.
- GlaxoSmithKline (GSK)
- Roche
- Sanofi
- AstraZeneca
- Eli Lilly & Co.
- Amgen
- Bristol Myers Squibb
- Boehringer Ingelheim
- Takeda Pharmaceutical
- Biogen
In this report, the profile of each market player provides following information:
- Market share analysis
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Drug Class
- Market Snapshot, By Application
- Market Snapshot, By Route of Administration
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Region
- Anti-Inflammatory Therapeutics Market Forces
- Drivers, Restraints and Opportunities
- Drivers
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Aging Population
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Biologic Innovations
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Rising Awareness
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- Restraints
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Side Effects
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Cost Constraints
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Patent Expiry
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- Opportunities
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Emerging Markets
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Personalized Medicine
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New Drug Approvals
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Anti-inflammatory Therapeutics Market, By Drug Class, 2021 - 2031 (USD Million)
- Anti-Inflammatory Biologics
- NSAIDs
- Others
- Anti-inflammatory Therapeutics Market, By Application, 2021 - 2031 (USD Million)
- Autoimmune Diseases
- Rheumatoid Arthritis
- Psoriasis
- Multiple Sclerosis
- Crohn's Disease
- Ulcerative Colitis
- Others
- Respiratory Conditions
- COPD
- Asthma
- Others
- Autoimmune Diseases
- Anti-inflammatory Therapeutics Market, By Route of Administration, 2021 - 2031 (USD Million)
- Oral
- Injection
- Topical
- Inhalation
- Anti-inflammatory Therapeutics Market, By Distribution Channel, 2021 - 2031 (USD Million)
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
- Anti-Inflammatory Therapeutics Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Anti-inflammatory Therapeutics Market, By Drug Class, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- AbbVie
- Pfizer
- Johnson & Johnson
- Novartis
- Merck & Co.
- GlaxoSmithKline (GSK)
- Roche
- Sanofi
- AstraZeneca
- Eli Lilly & Co.
- Amgen
- Bristol Myers Squibb
- Boehringer Ingelheim
- Takeda Pharmaceutical
- Biogen
- Company Profiles
- Analyst Views
- Future Outlook of the Market

