Anti-rheumatics Market
By Type;
Prescription-Based Drugs and Over-The-Counter DrugsBy Drug Class;
Disease Modifying Anti-Rheumatic Drugs (DMARDs), Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Corticosteroids, Uric Acid Drugs and OthersBy Route of Drug Administration;
Oral, Parenteral and OthersBy Distribution Channel;
Hospital Pharmacies, Retail Pharmacies and E-CommerceBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Anti-Rheumatics Market Overview
Anti-Rheumatics Market (USD Million)
Anti-Rheumatics Market was valued at USD 68,014.68 million in the year 2024. The size of this market is expected to increase to USD 83,195.75 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 2.9%.
Anti-rheumatics Market
*Market size in USD million
CAGR 2.9 %
| Study Period | 2025 - 2031 |
|---|---|
| Base Year | 2024 |
| CAGR (%) | 2.9 % |
| Market Size (2024) | USD 68,014.68 Million |
| Market Size (2031) | USD 83,195.75 Million |
| Market Concentration | High |
| Report Pages | 338 |
Major Players
- AbbVie Inc.
- Pfizer Inc.
- Novartis AG
- Amgen Inc.
- Johnson & Johnson
- Merck & Co., Inc.
- Roche Holding AG
- Bristol Myers Squibb Company
- Eli Lilly and Company
- GlaxoSmithKline plc
- AstraZeneca PLC
- Takeda Pharmaceutical Company Limited
- Biogen Inc.
- Sanofi S.A.
- Boehringer Ingelheim International GmbH
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Anti-rheumatics Market
Fragmented - Highly competitive market without dominant players
Anti-Rheumatics Market is rapidly evolving with growing demand for effective therapies targeting chronic inflammatory joint conditions. A notable shift is seen as 65% of individuals prefer combination drug therapies, emphasizing the need for integrated treatment solutions. Ongoing developments continue to enhance the therapeutic capabilities of anti-rheumatic drugs.
Increasing Prevalence of Autoimmune Disorders
The persistent rise in rheumatic disease cases is pushing demand across the pharmaceutical landscape. With diagnosis rates climbing by 20%, healthcare systems are witnessing a surge in patients requiring long-term management. This growing patient pool is propelling research into more efficient and durable anti-rheumatic solutions.
Emphasis on Individualized Care Models
Personalized medicine is gaining momentum in anti-rheumatic treatments. Nearly 33% of active trials focus on biomarker-driven therapies, offering customized approaches to disease control. These precision-guided interventions are improving patient compliance and accelerating market acceptance of targeted drugs.
Collaborative Ecosystem Enhancing Innovation
A surge in partnerships among biotech firms and pharmaceutical innovators is driving growth. Collaborative projects have increased by 28%, promoting the development of next-generation biologics and biosimilars. This trend is helping streamline treatment costs while expanding therapeutic accessibility worldwide.
Anti-rheumatics Market Key Takeaways
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Anti-rheumatics Market is growing steadily due to the rising global incidence of rheumatoid arthritis and other autoimmune diseases affecting joint and connective tissues.
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Increasing adoption of biologic and targeted synthetic DMARDs (disease-modifying antirheumatic drugs) is transforming the treatment landscape by offering higher efficacy and improved safety profiles.
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Advancements in monoclonal antibody therapy and biosimilars are expanding patient access to cost-effective alternatives for chronic inflammatory conditions.
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Growing awareness of early diagnosis and improved availability of rheumatology care are contributing to better treatment adherence and quality of life for patients.
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The market is seeing continuous innovation in oral formulations and combination therapies to enhance patient convenience and compliance.
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North America and Europe dominate due to strong healthcare infrastructure and widespread use of biologics, while Asia-Pacific shows high potential with growing healthcare investments.
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Key pharmaceutical companies are focusing on clinical trials and collaborations to develop novel immunotherapies that target specific pathways in rheumatoid and osteoarthritis.
Anti-Rheumatics Market Recent Developments
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In April 2025, Organon acquired the U.S. regulatory and commercial rights to TOFIDENCE (tocilizumab-bavi), reinforcing its position in the anti-rheumatic biologics market. This strategic move expands Organon’s immunology portfolio and enhances its role in delivering advanced treatments for inflammatory and autoimmune disorders.
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In May 2024, Teva, in partnership with Alvotech, introduced SIMLANDI (adalimumab-ryvk), expanding its anti-rheumatic drug portfolio with a new biosimilar therapy. This launch enhances access to advanced treatment options for patients while strengthening Teva’s presence in the biologic medicines market.
Anti-rheumatics Market Segment Analysis
In this report, the Anti-rheumatics Market has been segmented by Type, Drug Class, Route of Drug Administration, Distribution Channel, and Geography. This segmentation is crucial for understanding the dynamics and market forces driving the adoption and development of anti-rheumatic therapies globally. The segmentation provides a roadmap for analyzing the market’s growth opportunities, technological advancements, and patient care innovations.
Anti-rheumatics Market, Segmentation by Type
The market is segmented by Type, distinguishing between prescription-based drugs and over-the-counter (OTC) drugs. Prescription drugs are typically used for more severe, chronic conditions, whereas OTC drugs provide symptomatic relief for milder conditions. The rise in chronic diseases and autoimmune disorders, coupled with an increasing aging population, is driving the demand for prescription-based drugs. Meanwhile, the growing preference for self-medication in mild cases contributes to the robust growth of the OTC drugs segment.
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Prescription-Based Drugs
Prescription-based drugs dominate the market as they are prescribed for managing severe symptoms and disease progression in conditions like rheumatoid arthritis and lupus. These medications typically include DMARDs and biologics, which require physician oversight due to their potency and potential side effects. The market for prescription drugs is growing, driven by the increasing prevalence of autoimmune diseases and the need for long-term treatment strategies.
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Over-The-Counter Drugs
Over-the-counter (OTC) drugs are widely used for the management of mild symptoms of pain and inflammation. NSAIDs such as ibuprofen and aspirin are often used by patients for short-term relief. The OTC drugs segment is growing rapidly, driven by the increasing preference for self-medication, convenience, and easy access to these medications in retail pharmacies.
Anti-rheumatics Market, Segmentation by Drug Class
Drug Class segmentation is crucial as it helps identify the underlying mechanism of action of various anti-rheumatic therapies. This categorization affects treatment strategies and market growth as companies focus on different drug classes to address varying patient needs, ranging from symptom management to disease modification. The segmentation is pivotal in understanding the development of novel therapies targeting the root causes of rheumatic diseases.
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Disease Modifying Anti-Rheumatic Drugs (DMARDs)
DMARDs are essential for controlling the progression of inflammatory diseases like rheumatoid arthritis and psoriatic arthritis. These drugs modify the course of the disease by targeting the immune system and preventing joint damage. The market for DMARDs is expanding rapidly as more biologic therapies are introduced, offering tailored solutions with fewer side effects than traditional treatments.
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Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are commonly used to relieve pain and reduce inflammation, particularly in the early stages of rheumatic diseases. These drugs are available over-the-counter and are essential in providing relief from acute flare-ups. While effective, the long-term use of NSAIDs can be limited by their side effects, such as gastrointestinal bleeding, which has spurred the development of newer, safer alternatives.
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Corticosteroids
Corticosteroids are potent anti-inflammatory drugs used to manage acute flare-ups and severe inflammation. While they are highly effective in controlling symptoms in the short term, long-term use is often associated with significant side effects, such as osteoporosis and weight gain, which has led to the shift toward more targeted treatments like biologics and DMARDs.
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Uric Acid Drugs
Uric acid drugs are primarily used for the management of gout, a type of inflammatory arthritis caused by high uric acid levels in the blood. These medications help lower uric acid levels and prevent gout attacks, with an increasing demand as the prevalence of gout rises in aging populations and those with metabolic syndrome.
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Others
The Others category includes newer therapeutic agents, such as Janus kinase (JAK) inhibitors and biologics targeting specific immune cells involved in rheumatic diseases. These therapies represent the next generation of treatments, offering highly targeted interventions with fewer systemic side effects.
Anti-rheumatics Market, Segmentation by Route of Drug Administration
Route of administration is a significant factor in patient adherence and treatment success. The choice of administration route impacts drug efficacy, convenience, and patient compliance, particularly for long-term treatments of chronic rheumatic diseases. This segmentation reveals preferences for oral, injectable, or topical therapies, depending on disease severity and treatment goals.
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Oral
Oral administration is the most commonly used method, especially for chronic diseases such as rheumatoid arthritis. Oral drugs like NSAIDs and DMARDs are convenient for long-term use and are often prescribed as the first line of treatment. Oral administration allows patients to self-manage their condition, improving treatment adherence.
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Parenteral
Parenteral routes, such as intravenous or subcutaneous administration, are used for biologic therapies and medications that require a faster or more controlled action. These routes are often used for severe cases of rheumatic diseases and for drugs like TNF inhibitors and interleukin inhibitors, which are delivered in a hospital or clinic setting.
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Others
The Others category includes less common routes, such as topical or intramuscular administration, which are used for localized treatments. While not as widespread, these routes are effective in managing specific symptoms, such as joint pain, without systemic effects.
Anti-rheumatics Market, Segmentation by Distribution Channel
Distribution channels define how anti-rheumatic drugs reach patients and are a crucial component of market access strategies. The growing reliance on retail pharmacies and e-commerce platforms is making treatments more accessible, especially for patients in remote areas. Pharmaceutical companies are increasingly investing in digital health solutions to support distribution and patient engagement.
- Hospital Pharmacies
Hospital pharmacies play a critical role in distributing drugs used for acute and specialty conditions. These pharmacies are pivotal in delivering biologics and other specialized treatments that require medical oversight. Hospital pharmacies work closely with healthcare providers to ensure that patients receive the most appropriate therapies.
- Retail Pharmacies
Retail pharmacies are essential for providing broad access to oral drugs, including NSAIDs and DMARDs. These pharmacies enable quick access to treatment for patients managing mild to moderate symptoms, improving treatment adherence and patient satisfaction. Retail pharmacies often offer OTC drugs, making them a critical part of the anti-rheumatics drug distribution network.
- E-Commerce
E-commerce platforms are rapidly gaining importance as they provide patients with a convenient, at-home access point for purchasing medications. E-commerce pharmacies are especially popular for chronic condition management, as they offer home delivery services and subscription models that ensure patients consistently receive their medications.
Anti-rheumatics Market, Segmentation by Geography
In this report, the Anti-rheumatics Market has been segmented by Geography into five regions: North America, Europe, Asia Pacific, Middle East & Africa, and Latin America. These regions represent varying levels of healthcare access, regulatory environments, and market dynamics, influencing the adoption of anti-rheumatic therapies.
Regions and Countries Analyzed in this Report
North America
North America is a key market for anti-rheumatic drugs, driven by advanced healthcare infrastructure, high healthcare expenditure, and increasing adoption of biologic treatments. The region also benefits from rapid regulatory approvals and strong market access for new therapies, enabling faster adoption.
Europe
Europe is seeing steady growth due to an aging population, increasing incidence of autoimmune diseases, and the rising demand for innovative therapies. The region is highly focused on value-based healthcare and health technology assessments, ensuring that treatments are both effective and cost-efficient.
Asia Pacific
Asia Pacific is experiencing rapid growth, driven by improving healthcare access, rising disposable incomes, and an increasing awareness of rheumatic diseases. The region's large population and diverse healthcare needs offer significant opportunities for market expansion.
Middle East & Africa
The Middle East & Africa market is expanding as healthcare systems improve across key markets, particularly in the Gulf Cooperation Council (GCC) countries. The increasing burden of chronic diseases and the adoption of advanced therapies are contributing to the growth of the anti-rheumatics market.
Latin America
Latin America offers growth opportunities driven by improved healthcare access, rising health awareness, and increased government spending on healthcare infrastructure. The market is evolving with partnerships and collaborations aimed at improving drug availability and patient outcomes.
Anti-Rheumatics Market Forces
This report provides an in depth analysis of various factors that impact the dynamics of Anti-Rheumatics Market. These factors include; Market Drivers, Restraints, and Opportunities.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces Drivers, Restraints, and Opportunities affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
| Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
|---|---|---|---|---|---|
| Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development |
| Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
| Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers:
- Increasing prevalence of rheumatic diseases
- Aging population
- Rising awareness and early diagnosis
- Growing healthcare expenditure
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Adoption of combination therapies - The adoption of combination therapies is a significant driver in the global anti-rheumatics market. Combination therapies, which involve the use of two or more medications to treat rheumatic diseases, have shown improved efficacy in managing symptoms and slowing disease progression compared to monotherapy. This approach can target different pathways of the disease simultaneously, enhancing overall treatment outcomes. As more clinical trials and studies validate the benefits of combination therapies, healthcare providers and patients increasingly favor them, boosting their adoption rates.
Combination therapies can help reduce the dosage of individual drugs, potentially minimizing side effects and improving patient adherence. This is particularly important in managing chronic conditions like rheumatoid arthritis, where long-term medication use is necessary. Pharmaceutical companies are investing heavily in research and development to create effective combination therapies, seeing them as a way to differentiate their products in a competitive market. The growing availability of these therapies is thus driving market growth, providing patients with more comprehensive treatment options.
Restraints:
- Adverse medication side effects
- Stringent regulations
- Patent expirations
- Slow drug approvals
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Patient adherence issues - Patient adherence issues are a significant restraint in the global anti-rheumatics market. Despite the availability of effective treatments, many patients struggle to consistently follow their prescribed medication regimens. This non-adherence can be attributed to various factors, including the complexity of treatment plans, side effects, forgetfulness, and a lack of understanding about the importance of continuous medication.
The chronic nature of rheumatic diseases often requires long-term treatment, which can lead to "treatment fatigue" among patients, making them less likely to adhere to their medication schedules. Additionally, the side effects associated with some anti-rheumatic drugs can discourage patients from maintaining their treatment plans. This inconsistency in medication adherence can result in suboptimal treatment outcomes, increased disease progression, and higher healthcare costs due to complications and hospitalizations.
Healthcare providers face challenges in ensuring patient adherence, necessitating increased efforts in patient education, simplified treatment regimens, and supportive technologies such as medication reminders and digital health tools. Addressing adherence issues is crucial for maximizing the effectiveness of anti-rheumatic treatments and improving patient quality of life.
Opportunities:
- Development of biosimilars
- Innovative drug delivery systems
- Telemedicine growth
- Personalized medicine
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Preventive care focus - Preventive care focus presents a significant opportunity in the global anti-rheumatics market. With the growing emphasis on preventive healthcare measures, there is increasing awareness about the importance of early diagnosis and intervention in managing rheumatic diseases. Preventive care strategies aim to identify individuals at risk of developing rheumatic conditions and intervene proactively to prevent disease onset or minimize its progression.
Implementing preventive care measures involves educating individuals about rheumatic diseases, promoting healthy lifestyle choices, and encouraging regular screenings and monitoring for early signs and symptoms. By emphasizing preventive care, healthcare systems can reduce the burden of rheumatic diseases by preventing or delaying disease onset, improving patient outcomes, and reducing healthcare costs associated with advanced disease management.
Preventive care strategies may include the use of pharmacological and non-pharmacological interventions, such as lifestyle modifications, dietary changes, exercise programs, and targeted medication regimens, to mitigate risk factors and reduce the likelihood of developing rheumatic conditions. Additionally, advancements in diagnostic technologies and predictive analytics enable healthcare providers to identify individuals at higher risk of developing rheumatic diseases and tailor preventive interventions accordingly.
Anti-rheumatics Market Competitive Landscape Analysis
Anti-rheumatics Market is witnessing substantial growth due to the increasing prevalence of rheumatic diseases such as rheumatoid arthritis, osteoarthritis, and psoriatic arthritis. Anti-rheumatic drugs, including disease-modifying anti-rheumatic drugs (DMARDs), biologics, and NSAIDs, play a vital role in managing symptoms and preventing disease progression. The market is projected to grow at a rate of 8% annually, driven by rising healthcare awareness, aging populations, and advancements in drug formulations for personalized treatment.
Market Structure and Concentration
The anti-rheumatics market is moderately concentrated, with a few major pharmaceutical companies dominating the market, alongside smaller specialized biotechnology firms. Leading players are focusing on the development of more effective biologics and targeted therapies that offer better results and fewer side effects for patients. Market concentration is expected to remain moderate, with top players accounting for around 55% of the total market share, while emerging players focus on niche therapeutic areas.
Brand and Channel Strategies
Companies in the anti-rheumatics market are focusing on building strong brands by emphasizing the efficacy, safety, and innovative formulations of their anti-rheumatic therapies. Distribution channels primarily include direct sales to healthcare providers, partnerships with pharmaceutical distributors, and collaborations with hospitals and specialty clinics. Marketing strategies often focus on educating patients and healthcare professionals about the benefits of new biologic treatments, driving adoption and market expansion.
Innovation Drivers and Technological Advancements
Innovation in the anti-rheumatics market is driven by advancements in biotechnology, genetic research, and precision medicine. The development of next-generation biologics, such as JAK inhibitors and monoclonal antibodies, is improving treatment outcomes for patients with autoimmune conditions. Additionally, personalized treatment plans that cater to the specific genetic and molecular profiles of patients are expected to play a key role in enhancing the effectiveness of therapies. The ongoing research into stem cell therapy and gene editing for autoimmune diseases is also contributing to the growth of the market.
Regional Momentum and Expansion
North America and Europe are leading the anti-rheumatics market, driven by a high prevalence of autoimmune diseases, advanced healthcare infrastructure, and strong government support for healthcare programs. However, the Asia-Pacific region is witnessing significant growth, fueled by rising healthcare investments, an aging population, and increasing access to advanced treatments. The Asia-Pacific market is expected to grow at a rate of 10% annually, with countries like China, India, and Japan playing a pivotal role in driving demand for anti-rheumatic therapies.
Future Outlook
The future outlook for the anti-rheumatics market is positive, with continued growth driven by advancements in biologic therapies, precision medicine, and personalized care approaches. As research into autoimmune diseases progresses and new therapeutic options are developed, the demand for targeted treatments will increase. The market is expected to grow by 8% annually over the next five years, with expanding opportunities in emerging markets and continued demand for improved treatment options in established markets.
Key players in Anti-Rheumatics Market include,
- AbbVie
- Roche / F. Hoffmann-La Roche
- Novartis
- Pfizer
- Johnson & Johnson
- Bristol-Myers Squibb
- Merck
- Amgen
- UCB
- Sanofi
- Takeda Pharmaceutical
- Biogen
- Celltrion
- GSK (GlaxoSmithKline)
- Teva Pharmaceutical
In this report, the profile of each market player provides following information:
- Market Share Analysis
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Drug Class
- Market Snapshot, By Route of Drug Administration
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Region
- Anti-rheumatics Market Forces
- Drivers, Restraints and Opportunities
- Drivers
- Increasing prevalence of rheumatic diseases
- Aging population
- Rising awareness and early diagnosis
- Growing healthcare expenditure
- Adoption of combination therapies
- Restraints
- Adverse medication side effects
- Stringent regulations
- Patent expirations
- Slow drug approvals
- Patient adherence issues
- Opportunities
- Development of biosimilars
- Innovative drug delivery systems
- Telemedicine growth
- Personalized medicine
- Preventive care focus
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Anti-rheumatics Market, By Type, 2021 - 2031 (USD Million)
- Prescription-Based Drugs
- Over-The-Counter Drugs
- Anti-rheumatics Market, By Drug Class, 2021 - 2031 (USD Million)
- Disease Modifying Anti-Rheumatic Drugs (DMARDs)
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- Corticosteroids
- Uric Acid Drugs
- Others
- Anti-rheumatics Market, By Route of Drug Administration, 2021 - 2031 (USD Million)
- Oral
- Parenteral
- Others
- Anti-rheumatics Market, By Distribution Channel, 2021 - 2031 (USD Million)
- Hospital Pharmacies
- Retail Pharmacies
- E-Commerce
- Anti-rheumatics Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Anti-rheumatics Market, By Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- AbbVie
- Roche / F. Hoffmann-La Roche
- Novartis
- Pfizer
- Johnson & Johnson
- Bristol-Myers Squibb
- Merck
- Amgen
- UCB
- Sanofi
- Takeda Pharmaceutical
- Biogen
- Celltrion
- GSK (GlaxoSmithKline)
- Teva Pharmaceutical
- Company Profiles
- Analyst Views
- Future Outlook of the Market

