Vascular Endothelial Growth Factor (VEGF) Inhibitors Market

By Type;

VEGF-A Inhibitor, VEGF-B Inhibitor, VEGF-C Inhibitor, and VEGF-D Inhibitor

By Drugs Type;

Avastin, Tecentriq, Cometriq, Eylea, and Others

By Route Of Administration;

Oral and Intravenous

By Application;

Oncology, Ophthalmology, and Others

By End-Users;

Hospitals, Homecare, Specialty Clinics, and Others

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn281945422 Published Date: August, 2025

Vascular Endothelial Growth Factor (VEGF) Inhibitors Market Overview

Vascular Endothelial Growth Factor (Vegf) Inhibitor Market (USD Million)

Vascular Endothelial Growth Factor (Vegf) Inhibitor Market was valued at USD 9,874.30 million in the year 2024. The size of this market is expected to increase to USD 18,342.42 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 9.3%.


Vascular Endothelial Growth Factor (VEGF) Inhibitors Market

*Market size in USD million

CAGR 9.3 %


Study Period2025 - 2031
Base Year2024
CAGR (%)9.3 %
Market Size (2024)USD 9,874.30 Million
Market Size (2031)USD 18,342.42 Million
Market ConcentrationMedium
Report Pages350
9,874.30
2024
18,342.42
2031

Major Players

  • Novartis AG
  • Roche Holding AG
  • Bayer AG
  • Regeneron Pharmaceuticals, Inc.
  • Genentech, Inc. (a subsidiary of Roche)
  • Pfizer Inc.
  • Eli Lilly and Company
  • Amgen Inc.
  • Merck & Co., Inc.
  • Sanofi S.A.

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Vascular Endothelial Growth Factor (VEGF) Inhibitors Market

Fragmented - Highly competitive market without dominant players


The Vascular Endothelial Growth Factor (VEGF) Inhibitors Market is witnessing significant momentum as these therapies become integral to cancer and eye disease management. Approximately 35% of oncology regimens incorporate VEGF inhibitors, underscoring their importance in controlling angiogenesis and slowing tumor growth.

Adoption in Ophthalmology Treatments
VEGF inhibitors are gaining prominence in eye care, with over 45% of retinal disorder treatments depending on them for effective management. They are particularly valuable in treating conditions such as age-related macular degeneration and diabetic retinopathy, where vision outcomes are greatly improved.

Innovation Driving Market Growth
Research and development are accelerating, with around 30% of therapeutic pipelines dedicated to VEGF inhibitors and related combination therapies. These innovations are focused on improving safety, extending treatment duration, and delivering higher efficacy for patients.

Institutional and Clinical Support
Healthcare institutions are increasingly prioritizing VEGF therapies, with more than 50% of clinical guidelines recommending their integration. This institutional backing is ensuring better accessibility and reaffirming the role of VEGF inhibitors in modern treatment strategies.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Type
    2. Market Snapshot, By Drugs Type
    3. Market Snapshot, By Route Of Administration
    4. Market Snapshot, By Application
    5. Market Snapshot, By End Users
    6. Market Snapshot, By Region
  4. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Innovation in therapies
        2. Increasing prevalence
        3. Growing investment
        4. Technological advancements
        5. Rising demand globally
      2. Restraints
        1. High treatment cost
        2. Regulatory hurdles
        3. Side effects concern
        4. Patent expirations
        5. Limited awareness
      3. Opportunities
        1. Emerging markets expansion
        2. Personalized medicine approach
        3. Collaborative research efforts
        4. Pipeline development
        5. Therapeutic advancements
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By Type,, 2021 - 2031 (USD Million)
      1. VEGF-A Inhibitor
      2. VEGF-B Inhibitor
      3. VEGF-C Inhibitor
      4. VEGF-D Inhibitor
    2. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By Drugs Type,, 2021 - 2031 (USD Million)
      1. Avastin
      2. Tecentriq
      3. Cometriq
      4. Eylea
      5. Others
    3. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By Route Of Administration, 2021 - 2031 (USD Million)
      1. Oral
      2. Intravenous
    4. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By Application, 2021 - 2031 (USD Million)
      1. Oncology
      2. Ophthalmology
      3. Others
    5. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By End Users, 2021 - 2031 (USD Million)
      1. Hospitals
      2. Homecare
      3. Specialty Clinics
      4. Others
    6. Vascular Endothelial Growth Factor (Vegf) Inhibitor Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Novartis AG
      2. Roche Holding AG
      3. Bayer AG
      4. Regeneron Pharmaceuticals, Inc.
      5. Genentech, Inc. (a subsidiary of Roche)
      6. Pfizer Inc.
      7. Eli Lilly and Company
      8. Amgen Inc.
      9. Merck & Co., Inc.
      10. Sanofi S.A.
  7. Analyst Views
  8. Future Outlook of the Market