Systemic Inflammatory Response Syndrome (SIRS) Treatment Market

By Indication;

Meningitis, Urinary Tract Infection (UTI), Pneumonia, Hemorrhage, Autoimmune Diseases, and Others

By Treatment Type;

Pharmacological Treatment and Non-Pharmacological Treatment

By Route of Administration;

Oral Administration and Intravenous Administration

By End User;

Hospital & Clinics, Diagnostic Centers, Home Care, and Others

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn128591318 Published Date: August, 2025 Updated Date: September, 2025

Systemic Inflammatory Response Syndrome (SIRS) Treatment Market Overview

Systemic Inflammatory Response Syndrome (SIRS) Treatment Market (USD Million)

Systemic Inflammatory Response Syndrome Treatment Market was valued at USD 14,344.82 million in the year 2024. The size of this market is expected to increase to USD 24,079.11 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 7.7%.


Systemic Inflammatory Response Syndrome (SIRS) Treatment Market

*Market size in USD million

CAGR 7.7 %


Study Period2025 - 2031
Base Year2024
CAGR (%)7.7 %
Market Size (2024)USD 14,344.82 Million
Market Size (2031)USD 24,079.11 Million
Market ConcentrationMedium
Report Pages384
14,344.82
2024
24,079.11
2031

Major Players

  • CytoSorbents Corporation
  • RegeneRx Biopharmaceuticals, Inc
  • Endacea, Inc
  • Adrenomed AG
  • GlaxoSmithKline plc
  • Asahi Kasei Corporation
  • Cardinal Health
  • Smith & Nephew plc
  • ConvaTec, Inc.
  • AstraZeneca
  • Orion Corporation
  • CHIESI Farmaceutici S.p.A
  • Mylan N.V

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Systemic Inflammatory Response Syndrome (SIRS) Treatment Market

Fragmented - Highly competitive market without dominant players


The Systemic Inflammatory Response Syndrome (SIRS) Treatment Market is expanding steadily as healthcare providers focus on advanced therapeutic approaches to manage this severe condition. Triggered by infections, trauma, or medical complications, SIRS requires rapid intervention to reduce mortality risks. Currently, nearly 65% of critical care patients undergo treatment protocols addressing systemic inflammation, underscoring the market’s crucial role in intensive care.

Growing Demand for Critical Care Therapies
More than 55% of intensive care facilities have adopted specialized therapies for SIRS management. These approaches enhance patient monitoring, reduce complications, and improve recovery outcomes, positioning SIRS treatments as a core component of critical care strategies.

Advancements in Therapeutic Approaches
Innovations in drug formulations and immunomodulatory therapies are reshaping treatment standards. Around 40% of newly developed interventions target improved immune regulation and reduced inflammatory response, allowing faster stabilization and patient recovery. These advancements are driving demand for evidence-based solutions in systemic inflammation care.

Integration of Monitoring and Supportive Care
Nearly 50% of patients with SIRS require intensive monitoring and supportive interventions such as fluid management, respiratory support, and hemodynamic stabilization. The integration of advanced monitoring technologies ensures better real-time assessments, guiding precise therapeutic decisions and boosting clinical outcomes.

Rising Adoption Across Healthcare Facilities
Today, almost 60% of hospitals and specialized centers have implemented standardized SIRS management protocols. Their widespread adoption demonstrates the growing importance of comprehensive treatment pathways and highlights the market’s strong trajectory, supported by advances in critical care practices and innovative therapies.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Indication
    2. Market Snapshot, By Treatment Type
    3. Market Snapshot, By Route of Administration
    4. Market Snapshot, By End User
    5. Market Snapshot, By Region
  4. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market Dynamics

    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Aging Population and Chronic Diseases

        2. Growing Awareness and Diagnosis Rates

        3. Rise in Surgical Procedures and Traumatic Injuries

        4. Emerging Therapeutic Approaches and Drug Development

      2. Restraints
        1. Government Initiatives and Funding Support

        2. Strategic Collaborations and Partnerships in Research

        3. Shift towards Personalized Medicine and Preision Therapeutics

        4. Favorable Reimbursement Policies and Healthcare Infrastructure

      3. Opportunities
        1. Clinical Uncertainties

        2. Resource Constraints

        3. Technological Limitations

        4. Cultural and Societal Factors

    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market, By Indication, 2021 - 2031 (USD Million)
      1. Hospital & Clinics
      2. Diagnostic Centers
      3. Home Care
      4. Others
    2. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market, By Treatment Type, 2021 - 2031 (USD Million)

      1. Pharmacological Treatment

      2. Non-Pharmacological Treatment

    3. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market, By Route of Administration, 2021 - 2031 (USD Million)

      1. Oral Administration

      2. Intravenous Administration

    4. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market, Market, By End User, 2021 - 2031 (USD Million)
      1. Meningitis
      2. Urinary Tract Infection (UTI)
      3. Pneumonia
      4. Hemorrhage
      5. Autoimmune Diseases
      6. Others
    5. Systemic Inflammatory Response Syndrome (SIRS) Treatment Market, By Geography, 2021 - 2031 (USD Million)
      1. North America

        1. United States

        2. Canada

      2. Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Nordic

        7. Benelux

        8. Rest of Europe

      3. Asia Pacific

        1. Japan

        2. China

        3. India

        4. Australia & New Zealand

        5. South Korea

        6. ASEAN (Association of South East Asian Countries)

        7. Rest of Asia Pacific

      4. Middle East & Africa

        1. GCC

        2. Israel

        3. South Africa

        4. Rest of Middle East & Africa

      5. Latin America

        1. Brazil

        2. Mexico

        3. Argentina

        4. Rest of Latin America

  6. Competitive Landscape
    1. Company Profiles
      1. CytoSorbents Corporation
      2. RegeneRx Biopharmaceuticals, Inc
      3. Endacea, Inc
      4. Adrenomed AG
      5. GlaxoSmithKline plc
      6. Asahi Kasei Corporation
      7. Cardinal Health
      8. Smith & Nephew plc
      9. ConvaTec, Inc.
      10. AstraZeneca
      11. Orion Corporation
      12. CHIESI Farmaceutici S.p.A
      13. Mylan N.V
  7. Analyst Views
  8. Future Outlook of the Market