Synthetic Genomics Market
By Product;
DNA Template, Modifying Enzymes, Adapters, Primers and Klenow FragmentBy Technology;
PCR and NGSBy Application;
Innovative Vaccines & Therapeutics, Bacterial Resistance, Organ Transplantation, DNA Printing and Nutritional Proteins & OilsBy End User;
Biotechnology Companies, Pharmaceutical Companies, Academic Institutions, Government Laboratories and Contract Research OrganizationsBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Synthetic Genomics Market Overview
Synthetic Genomics Market (USD Million)
Synthetic Genomics Market was valued at USD 34,536.14 million in the year 2024. The size of this market is expected to increase to USD 79,880.81 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 12.7%.
Synthetic Genomics Market
*Market size in USD million
CAGR 12.7 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 12.7 % |
Market Size (2024) | USD 34,536.14 Million |
Market Size (2031) | USD 79,880.81 Million |
Market Concentration | Low |
Report Pages | 399 |
Major Players
- Synthetic Genomics Inc
- Ginkgo Bioworks
- Twist Bioscience
- DNA Script
- Codexis Inc
- Amyris Inc
- Intrexon Corporation (now part of Precigen Inc)
- Genomatica Inc
- Bluebird Bio Inc
- Arzeda
- Evolva
- TeselaGen Biotechnology
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Synthetic Genomics Market
Fragmented - Highly competitive market without dominant players
The Synthetic Genomics Market is expanding swiftly as biotech firms and research institutions increasingly leverage custom-designed genomic constructs for applications in therapeutics, industrial enzymes, and agricultural innovation. Over 65% of leading bioengineering labs now incorporate synthetic DNA and RNA molecules to program cellular behavior and metabolic pathways. This surge is propelling enhanced innovation and market expansion, fostered by joint efforts between computational biologists and molecular engineers.
Advanced Synthesis Tools Accelerating Design
Approximately 62% of technology providers are upgrading offerings with features such as high-throughput DNA synthesis, automated gene circuit validation, scalable plasmid libraries, and integrated in silico design platforms. These technological advancements elevate accuracy, reduce experimental iteration times, and streamline synthetic biology workflows. Cross-functional collaborations between software developers and bench scientists are accelerating these capabilities.
Partnerships Fueling Scale-Up and Services
Close to 63% of recent market momentum arises from strategic alliances and service partnerships linking DNA synthesis firms, bioprocess equipment vendors, and contract research organizations. These deals facilitate turnkey engineering-to-manufacturing workflows, reinforce scale‑up capabilities, and improve biomanufacturing resilience—driving sustained market expansion.
AI and Digital Twins Shaping Next‑Gen Platforms
Looking ahead, more than 70% of next-generation synthetic genomics platforms are projected to support AI-guided genome design, cell‑free rapid prototyping, and digital twin modeling for strain optimization. These triggers will usher in a new era of precision bioengineering and rapid innovation, significantly reducing time-to-market and unleashing new bio‑based product pipelines.
Synthetic Genomics Market Key Takeaways
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Synthetic genomics innovation is advancing biotechnology, enabling genome editing, synthetic DNA design, and metabolic engineering across industries.
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Rising investments fuel the sector, with over 40% of funding directed toward healthcare and pharmaceutical applications.
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Gene synthesis and editing dominate adoption, contributing to more than 35% of usage in drug discovery and precision medicine.
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Personalized medicine demand drives nearly 45% of synthetic genomics research, supporting biomarker development and targeted therapies.
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Agricultural biotechnology benefits from synthetic genomics through improved crop yields, disease resistance, and sustainable farming practices.
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North America leads the market, holding close to 38–40% share, supported by strong research infrastructure and government initiatives.
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Asia-Pacific emerges fastest-growing, contributing nearly 30% of expansion with heavy investments in genomics research and bio-manufacturing.
Synthetic Genomics Market Recent Developments
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In January 2021, Merck completed the acquisition of AmpTec (Germany), enhancing its expertise in advanced biotechnology. This move expanded Merck’s mRNA product portfolio, strengthening capabilities in the development and manufacturing of vaccines, novel treatments, and cutting-edge diagnostics.
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In February 2021, Merck entered into a strategic partnership with BioNTech (Germany) to provide essential lipids supporting the large-scale production of the Pfizer-BioNTech COVID-19 Vaccine (BNT162b2). This collaboration reinforced Merck’s role in advancing vaccine manufacturing during the pandemic.
Synthetic Genomics Market,Segment Analysis
In this report, the Synthetic Genomics Market has been segmented by Product, Application, End User and Geography.
Synthetic Genomics Market, Segmentation by Product
The Synthetic Genomics Market has been segmented by Product into DNA Template, Modifying Enzymes, Adapters, Primers and Klenow Fragment.
DNA Template
DNA templates form the backbone of synthetic genomics, providing the initial sequence from which synthetic genes are developed. With advancements in gene editing and gene synthesis, the demand for high-fidelity templates is growing rapidly. This segment accounts for approximately 28% of the product share due to its foundational role in genomic applications.
Modifying Enzymes
Modifying enzymes are essential for manipulating DNA sequences in synthetic biology. These enzymes support tasks such as ligation, phosphorylation, and methylation, contributing to functional gene constructs. This segment holds nearly 25% market share and is widely utilized across research and clinical diagnostics.
Adapters
Adapters are short DNA sequences used for ligating synthetic fragments to vectors or other DNA strands, enabling downstream sequencing and cloning processes. With the increasing demand in next-generation sequencing, adapters represent close to 18% of the market. Their role in library preparation workflows enhances their adoption in biotech applications.
Primers
Primers are critical for initiating DNA synthesis, making them indispensable in PCR and gene editing workflows. This segment is witnessing robust demand across academic and industrial labs, accounting for nearly 20% of the overall market. The growing prevalence of targeted gene therapies continues to fuel primer usage.
Klenow Fragment
The Klenow Fragment, a DNA polymerase derived from E. coli, is widely used in DNA labeling, blunt-end formation, and primer extension. Though a niche product, it maintains relevance in precision genetic modifications and represents about 9% of the total market.
Synthetic Genomics Market, Segmentation by Application
The Synthetic Genomics Market has been segmented by Application into Innovative vaccines & Therapeutics, Bacterial Resistance, Organ Transplantation, DNA Printing and Nutritional Proteins & Oils.
Innovative Vaccines & Therapeutics
Synthetic genomics plays a transformative role in developing next-generation vaccines and therapeutics. Engineered DNA sequences enable rapid response to emerging diseases and support personalized medicine. This segment accounts for nearly 32% of the total application market due to rising demand for mRNA platforms and genomic-based drug development.
Bacterial Resistance
Addressing antibiotic resistance using synthetic genomic technologies is becoming increasingly crucial. By designing novel antimicrobial compounds and resistance-modifying genes, researchers are tackling the AMR crisis. This sub-segment represents approximately 21% of the market.
Organ Transplantation
Synthetic biology enables advances in xenotransplantation and reduces organ rejection through gene editing. These tools are applied to customize donor organs and improve immune compatibility. Organ transplantation applications currently hold around 17% market share.
DNA Printing
DNA printing technologies such as on-demand gene synthesis and digital-to-biological conversion are transforming lab workflows. This segment captures nearly 15% of the market, supporting applications like drug screening and prototyping.
Nutritional Proteins & Oils
Synthetic genomics is revolutionizing the development of bioengineered proteins and functional oils used in nutraceuticals and functional foods. With growing interest in plant-based alternatives and sustainable nutrition, this sub-segment holds about 15% of the market.
Synthetic Genomics Market, Segmentation by End User
The Synthetic Genomics Market has been segmented by End User into Biotechnology Companies, Pharmaceutical Companies, Academic Institutions, Government Laboratories and Contract Research Organizations.
Biotechnology Companies
Biotechnology companies form a major end-user group in the synthetic genomics market, leveraging engineered DNA tools for drug discovery, cell engineering, and biomanufacturing. They account for around 34% of the market, driven by increasing investment in gene synthesis platforms and custom DNA constructs.
Pharmaceutical CompaniesPharmaceutical firms utilize synthetic genomics to streamline vaccine development, precision medicine, and biologic drug production. With the growing adoption of genomic approaches in drug pipelines, this segment holds nearly 26% of the market.
Academic InstitutionsAcademic institutions contribute significantly to foundational research in synthetic biology and gene circuit design. They represent about 18% of the market, playing a vital role in advancing novel genomic technologies and developing future expertise.
Government LaboratoriesGovernment labs support national-level initiatives in biosecurity, pandemic preparedness, and environmental genomics. These institutions make up roughly 12% of the market, with focus on synthetic organisms and public health innovation.
Contract Research OrganizationsCROs provide outsourced R&D services for synthetic genomic projects. Representing around 10% of the market, they offer specialized capabilities in DNA synthesis, regulatory testing, and clinical trial support across therapeutic pipelines.
Synthetic Genomics Market, Segmentation by Geography
In this report, the Synthetic Genomics Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
Synthetic Genomics Market Share (%), by Geographical Region
North America
North America dominates the synthetic genomics market, accounting for approximately 39% of the share. The region benefits from advanced biotech infrastructure, strong R&D funding, and early adoption of gene synthesis technologies, particularly across the United States and Canada.
EuropeEurope holds a significant market share of around 26%, driven by increased investments in synthetic biology research, government-backed initiatives, and robust academic collaborations. Countries like Germany, the UK, and France are leading in genome engineering and biomanufacturing innovation.
Asia PacificAsia Pacific is experiencing rapid growth and currently contributes about 21% to the market. Expanding biotech industries, rising genomic research funding, and growing participation in clinical trials across countries like China, India, and Japan are fueling regional momentum.
Middle East and AfricaThe Middle East and Africa represent a smaller share of approximately 7%, but growing interest in biotechnology infrastructure, genomic surveillance, and public health initiatives is gradually expanding opportunities, especially in Gulf nations and South Africa.
Latin AmericaLatin America holds close to 7% of the market, supported by increasing academic research activities and emerging investments in synthetic biology platforms. Brazil and Mexico are showing steady progress in areas like agricultural genomics and diagnostics.
Synthetic Genomics Market Forces
This report provides an in depth analysis of various factors that impact the dynamics of Synthetic Genomics Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces Drivers, Restraints and Opportunities affect key business dimensions including Growth, Competition, Customer Behavior, Regulation and Innovation.
Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
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Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development |
Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers, Restraints and Opportunity Analysis
Drivers
- Agricultural biotechnology
- Industrial biotechnology
- Sustainable solutions
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Renewable energy -The synthetic genomics market is increasingly intertwined with the renewable energy sector, offering innovative solutions for sustainable energy production. Synthetic genomics technologies are revolutionizing the way renewable energy sources are produced, optimized, and utilized. This convergence is particularly evident in the development of biofuels, a key area where synthetic genomics is making significant strides. Synthetic genomics plays a pivotal role in biofuel production by engineering microorganisms to efficiently convert biomass into fuels such as ethanol, biodiesel, and bio-jet fuel. Through synthetic biology techniques, researchers can design and optimize microbial pathways for enhanced biomass degradation and biofuel synthesis. These engineered microorganisms exhibit improved traits such as higher substrate tolerance, increased productivity, and reduced production costs, making biofuels more economically viable and environmentally sustainable alternatives to fossil fuels.
Algae-based biofuels represent a promising avenue for renewable energy production, and synthetic genomics is driving advancements in this field. By manipulating the genetic makeup of algae strains, researchers can enhance lipid accumulation, biomass productivity, and overall lipid content, crucial factors for efficient biofuel production. Synthetic genomics enables the creation of designer algae with tailored traits optimized for biofuel synthesis, paving the way for scalable and cost-effective algal biofuel production. Synthetic genomics is facilitating the production of renewable chemicals from biomass-derived feedstocks. By engineering microorganisms to biosynthesize valuable chemicals and materials, such as bioplastics, biochemicals, and specialty chemicals, synthetic genomics enables the sustainable production of a wide range of industrial products. These renewable chemicals offer eco-friendly alternatives to petroleum-derived counterparts, contributing to the transition towards a bio-based economy and reducing reliance on finite fossil resources.
Synthetic genomics also holds promise for environmental remediation efforts, particularly in the cleanup of contaminated sites and the mitigation of pollution. Engineered microorganisms can be designed to metabolize and degrade pollutants, including hydrocarbons, heavy metals, and toxic chemicals, through tailored enzymatic pathways. By harnessing the power of synthetic biology, researchers can develop microbial strains with enhanced bioremediation capabilities, facilitating the restoration of ecosystems and mitigating environmental impacts associated with industrial activities.
Restraints
- High research and development costs
- Intellectual property issues
- Safety and biosecurity risks
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Limited public acceptance -Despite its promising potential, the synthetic genomics market faces challenges stemming from limited public acceptance. This reluctance or skepticism from the public can be attributed to several factors. Ethical concerns surround the manipulation of genetic material. The ability to engineer or even create synthetic organisms raises questions about the implications for biodiversity, ecological balance, and potential unforeseen consequences in the environment. There are also ethical dilemmas regarding the creation of synthetic life forms and the ethical boundaries of genetic engineering.
Safety concerns loom large. The fear of unintended consequences or accidental release of engineered organisms into the environment creates apprehension among the public. Instances of genetic modifications gone awry in the past, whether in research or commercial settings, contribute to this skepticism. The perception of synthetic genomics as a complex and esoteric field can lead to misunderstandings and mistrust. The terminology and concepts involved in genetic engineering may be inaccessible to the general public, fostering a sense of unease or suspicion.
Societal and cultural factors play a role. Religious or cultural beliefs may conflict with certain applications of synthetic genomics, leading to resistance or opposition. Additionally, concerns about the commercialization of genetic resources and the unequal distribution of benefits exacerbate public skepticism. These challenges requires transparent communication, robust regulatory frameworks, and meaningful engagement with stakeholders. Efforts to educate the public about the benefits, risks, and ethical considerations of synthetic genomics are essential for building trust and fostering acceptance. Collaboration between scientists, policymakers, ethicists, and the public can help navigate the complexities of synthetic genomics responsibly and ethically, ensuring that its potential benefits are realized while minimizing its risks.
Opportunities
- Bio-based manufacturing
- Gene editing technologies
- Synthetic biology platforms
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Therapeutic applications -The therapeutic applications of synthetic genomics are at the forefront of medical innovation, offering promising solutions for a wide range of diseases and conditions. One of the most significant areas of focus is the development of innovative vaccines and therapeutics. Synthetic genomics enables researchers to design and engineer vaccines tailored to specific pathogens, including viruses, bacteria, and parasites. This targeted approach allows for the rapid development of vaccines to combat emerging infectious diseases and improve existing vaccination strategies. Synthetic genomics plays a crucial role in the development of personalized medicine. By analyzing individual genetic profiles, researchers can identify genetic factors contributing to diseases and tailor treatments to patients' specific genetic makeup. This approach holds immense potential for improving treatment outcomes and reducing adverse effects by optimizing therapies based on patients' genetic characteristics.
Another therapeutic application of synthetic genomics is in the field of gene therapy. Gene therapy involves introducing genetic material into cells to correct or replace defective genes associated with inherited disorders or acquired diseases. Synthetic genomics enables the design and synthesis of therapeutic DNA or RNA sequences for delivery into target cells, offering potential cures or long-term treatments for genetic disorders, cancer, and other diseases. Synthetic genomics is advancing regenerative medicine by facilitating the engineering of tissues and organs for transplantation. By combining synthetic biology techniques with tissue engineering approaches, researchers can create functional tissues and organs using bioengineered scaffolds seeded with patient-derived cells. This approach holds promise for overcoming the limitations of traditional organ transplantation, such as donor shortages and immune rejection, ultimately improving patient outcomes and quality of life.
These therapeutic applications, synthetic genomics is driving innovations in drug discovery and development. By designing synthetic DNA libraries encoding millions of unique compounds, researchers can rapidly screen for potential drug candidates against various targets, accelerating the drug discovery process and expanding the pharmacological toolbox for treating diseases. Overall, the therapeutic applications of synthetic genomics are revolutionizing healthcare by offering personalized, precise, and targeted treatments for a wide range of diseases and conditions. As research in synthetic genomics continues to advance, the potential for transformative breakthroughs in medicine remains high, paving the way for improved patient care and outcomes.
Synthetic Genomics Market Competitive Landscape Analysis
Synthetic Genomics Market is witnessing intensified competition as companies emphasize advanced strategies, collaborative partnerships, and targeted innovation to strengthen their positions. Nearly 60% of leading participants are expanding their research investments to secure intellectual property and accelerate growth across industrial, healthcare, and agricultural applications, highlighting the importance of merger and collaboration in shaping the competitive environment.
Market Structure and Concentration
The market demonstrates moderate concentration, with around 45% of revenues accounted for by top firms employing specialized strategies. Mergers and partnerships are frequently utilized to consolidate expertise, while expansion into niche applications drives differentiation. This concentration underscores the critical role of technological advancements and collaboration in shaping market stability and leadership.
Brand and Channel Strategies
Leading players implement sophisticated brand positioning and multi-channel strategies to capture diverse customer bases. Over 55% of companies leverage partnerships with academic institutions and private labs to enhance distribution credibility. These strategies emphasize innovation and customer engagement, ensuring strong visibility and supporting sustained growth in competitive environments.
Innovation Drivers and Technological Advancements
More than 70% of firms prioritize continuous innovation as a driver for expansion, with technological advancements in genome editing and bioinformatics at the forefront. Investment in digital platforms and AI-driven analytics fosters improved precision and accelerated timelines. Such approaches reinforce strategies for collaboration and secure competitive differentiation in the evolving synthetic genomics market.
Regional Momentum and Expansion
Regional leaders capture nearly 50% of overall activity by adopting expansion-driven strategies in high-demand markets. Partnerships with local enterprises and research centers enhance adaptability, while mergers accelerate market entry. This emphasis on regional growth highlights the importance of tailored strategies and technological collaborations to build momentum and scale operations effectively.
Future Outlook
The future outlook indicates over 65% of firms are expected to enhance their reliance on partnerships and joint research to sustain growth. With increasing focus on technological advancements and strategic collaboration, the market is likely to experience significant expansion. Companies adopting forward-looking strategies are positioned to shape the trajectory of the synthetic genomics industry.
Key players in Synthetic Genomics Market include.
- Bota Biosciences
- Codexis, Inc.
- Creative Biogene
- Creative Enzymes
- EnBiotix, Inc.
- Illumina, Inc.
- Merck KGaA (Sigma-Aldrich)
- New England Biolabs
- Eurofins Scientific
- Novozymes
- Pareto Bio, Inc.
- Scarab Genomics, LLC
- Synthego
- Synthetic Genomics Inc.
- Thermo Fisher Scientific, Inc.
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Market Share Analysis
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product
- Market Snapshot, By Technology
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Synthetic Genomics Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
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Agricultural biotechnology
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Industrial biotechnology
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Sustainable solutions
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Renewable energy
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- Restraints
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High research and development costs
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Intellectual property issues
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Safety and biosecurity risks
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Limited public acceptance
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- Opportunities
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Bio-based manufacturing
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Gene editing technologies
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Synthetic biology platforms
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Therapeutic applications
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Synthetic Genomics Market, By Product, 2021 - 2031 (USD Million)
- DNA Template
- Modifying Enzymes
- Adapters
- Primers
- Klenow Fragment
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Synthetic Genomics Market, By Technology, 2021 - 2031 (USD Million)
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PCR
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NGS
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- Synthetic Genomics Market, By Application, 2021 - 2031 (USD Million)
- Innovative Vaccines & Therapeutics
- Bacterial Resistance
- Organ Transplantation
- DNA Printing
- Nutritional Proteins & Oils
- Synthetic Genomics Market, By End User, 2021 - 2031 (USD Million)
- Biotechnology Companies
- Pharmaceutical Companies
- Academic Institutions
- Government Laboratories
- Contract Research Organizations
- Synthetic Genomics Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Synthetic Genomics Market, By Product, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Bota Biosciences
- Codexis, Inc.
- Creative Biogene
- Creative Enzymes
- EnBiotix, Inc.
- Illumina, Inc.
- Merck KGaA (Sigma-Aldrich)
- New England Biolabs
- Eurofins Scientific
- Novozymes
- Pareto Bio, Inc.
- Scarab Genomics, LLC
- Synthego
- Synthetic Genomics Inc.
- Thermo Fisher Scientific, Inc.
- Company Profiles
- Analyst Views
- Future Outlook of the Market