Global Synthetic Genomics Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Product;
DNA Template, Modifying Enzymes, Adapters, Primers, and Klenow Fragment.By Application;
Innovative Vaccines & Therapeutics, Bacterial Resistance, Organ Transplantation, DNA Printing, and Nutritional Proteins & Oils.By End User;
Biotechnology Companies, Pharmaceutical Companies, Academic Institutions, Government Laboratories, and Contract Research Organizations.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa, and Latin America - Report Timeline (2021 - 2031).Introduction
Global Synthetic Genomics Market (USD Million), 2021 - 2031
In the year 2024, the Global Synthetic Genomics Market was valued at USD 34,536.14 million. The size of this market is expected to increase to USD 79,880.81 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 12.7%.
The global synthetic genomics market has witnessed significant growth over recent years, driven by advancements in biotechnology, increasing investments in research and development, and the expanding application of synthetic biology across various industries. Synthetic genomics, a sub-discipline of synthetic biology, involves the design and construction of new genetic sequences, as well as the redesign of existing ones, to create organisms with novel properties or enhanced functions. This burgeoning field is revolutionizing areas such as medicine, agriculture, and industrial biotechnology, offering innovative solutions to some of the world's most pressing challenges.
In medicine, synthetic genomics is paving the way for personalized treatments and therapies. By designing custom genetic sequences, researchers can develop targeted gene therapies for diseases such as cancer, genetic disorders, and infectious diseases. The ability to manipulate and engineer genomes with precision is also accelerating the development of vaccines and novel drug therapies, making treatments more effective and tailored to individual patient needs. Furthermore, synthetic genomics holds promise for regenerative medicine, with the potential to create synthetic tissues and organs for transplantation.
Agriculture is another sector experiencing transformative changes due to synthetic genomics. The technology is being utilized to engineer crops with improved yield, nutritional value, and resistance to pests and environmental stresses. This not only enhances food security but also promotes sustainable agricultural practices by reducing the reliance on chemical inputs such as pesticides and fertilizers. Synthetic genomics also enables the development of biofuels from engineered microorganisms, offering a renewable and environmentally friendly alternative to fossil fuels. Industrial biotechnology is benefiting from synthetic genomics through the creation of bio-based chemicals, materials, and processes. Engineered microorganisms are being employed to produce biofuels, biodegradable plastics, and other high-value products, providing sustainable solutions to traditional manufacturing processes. This shift towards bio-manufacturing is driving the market for synthetic genomics, as companies seek to reduce their carbon footprint and develop eco-friendly products.
Global Synthetic Genomics Market Recent Developments
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In January 2021, Merck acquired AmpTec (Germany). With this acquisition, the company strengthened its product portfolio to develop and manufacture mRNA for utilizing vaccines, treatments, and diagnostics.
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In February 2021, Merck partnered with BioNTech (Germany) to supply lipids for the production of Pfizer-BioNTech COVID-19 Vaccine (BNT162b2).
Segment Analysis
The Global Synthetic Genomics Market has been segmented by Product, Application, End User and Geography, product into synthetic DNA, oligonucleotides, synthetic genes, and others. Synthetic DNA is the largest product segment, driven by its widespread use in gene synthesis, cloning, and genomic research. This product is crucial for creating custom DNA sequences used in various applications, including gene editing and synthetic biology. Oligonucleotides, which are short DNA or RNA molecules, are extensively used in diagnostics, PCR, and gene sequencing, contributing significantly to market growth. Synthetic genes, which are artificially created to mimic natural genes, are becoming increasingly important in areas like gene therapy, biotechnology, and industrial applications. The "others" segment includes various tools and reagents used in the synthesis and manipulation of genomic material, supporting the broader market for synthetic genomics.
By application, the market is segmented into gene editing, diagnostics, therapeutics, agriculture, and others. Gene editing, particularly through CRISPR-Cas9 and other gene-editing technologies, represents a significant application of synthetic genomics, enabling precise modifications of genetic material. The increasing use of synthetic genomics in diagnostics, including next-generation sequencing (NGS) and molecular diagnostics, is driving the demand for synthetic DNA and other products. Therapeutics, such as gene therapies and RNA-based treatments, are also rapidly growing, with synthetic genomics playing a key role in developing personalized medicine. Agriculture, particularly in the development of genetically modified crops and synthetic biology solutions for improving crop yields and pest resistance, is another key application. The "others" segment includes industrial applications of synthetic genomics, such as the production of biofuels and synthetic materials.
The market is segmented by end-user into research institutions, biotechnology companies, pharmaceutical companies, and others. Research institutions are the largest end-users of synthetic genomics products, as they are at the forefront of genomic research and advancements in gene editing, synthetic biology, and related fields. Biotechnology and pharmaceutical companies use synthetic genomics for drug discovery, gene therapies, and the development of innovative biotechnological solutions. These companies are heavily investing in synthetic genomics to create new treatments, particularly for genetic disorders and cancer. Other end-users include agricultural companies, which leverage synthetic genomics for genetically modified crops, and industrial firms focused on bioengineering and sustainable production. Geographically, North America leads the market, driven by significant investments in research and development, strong healthcare infrastructure, and the presence of leading biotechnology and pharmaceutical companies. Europe and Asia Pacific follow, with Asia Pacific showing the fastest growth due to increasing investment in biotechnology and synthetic biology across emerging economies like China and India.
Global Synthetic Genomics Segment Analysis
In this report, the Global Synthetic Genomics Market has been segmented by Product, Application, End User and Geography.
Global Synthetic Genomics Market, Segmentation by Product
The Global Synthetic Genomics Market has been segmented by Product into DNA Template, Modifying Enzymes, Adapters, Primers and Klenow Fragment.
DNA Templates are foundational elements in synthetic genomics, providing the essential genetic blueprints required for a variety of applications, including gene synthesis, cloning, and synthetic biology research. These templates are designed sequences of DNA that can be customized for specific experimental needs, enabling researchers to create or modify organisms with unprecedented precision.
Modifying Enzymes are another critical component in this market, encompassing a range of enzymes that facilitate the manipulation of DNA and RNA molecules. These enzymes, such as restriction endonucleases, ligases, and polymerases, are indispensable for tasks like cutting, joining, and amplifying nucleic acids. Their ability to precisely alter genetic material is fundamental to numerous applications, from basic research to therapeutic development. Adapters serve as essential tools in the synthesis and sequencing of DNA. These short, synthetic nucleic acid sequences are used to link fragments of DNA together, enabling the creation of longer DNA molecules necessary for various genomic studies and applications. Adapters are crucial in next-generation sequencing technologies, where they are used to prepare DNA libraries for sequencing.
Primers are short strands of nucleic acid that provide a starting point for DNA synthesis. In the context of synthetic genomics, primers are used in polymerase chain reactions (PCR) and other amplification techniques to selectively replicate specific segments of DNA. Their design and specificity are vital for the accuracy and efficiency of these processes, impacting applications ranging from diagnostic assays to genetic engineering. Large fragment of DNA polymerase I used in molecular biology for DNA synthesis and sequencing. This enzyme fragment retains the polymerase activity but lacks the exonuclease activity of the full enzyme, making it useful for certain types of DNA manipulations. The Klenow Fragment is particularly valuable in cloning and sequencing applications where high fidelity DNA synthesis is required.
Global Synthetic Genomics Market, Segmentation by Application
The Global Synthetic Genomics Market has been segmented by Application into Innovative vaccines & Therapeutics, Bacterial Resistance, Organ Transplantation, DNA Printing and Nutritional Proteins & Oils.
Another critical application of synthetic genomics is in combating bacterial resistance. The rise of antibiotic-resistant bacteria poses a severe threat to global health, necessitating new approaches to treatment. Synthetic genomics allows for the design of new antibiotics and alternative therapies that can overcome resistance mechanisms. By leveraging synthetic biology techniques, researchers can create more potent antibacterial agents and develop strategies to modify bacterial genomes, rendering them less capable of resisting existing treatments.
Organ transplantation is another area where synthetic genomics is making a significant impact. The shortage of donor organs is a longstanding issue, and synthetic genomics offers potential solutions through the creation of bioengineered organs. By using synthetic DNA to modify and grow tissues that are less likely to be rejected by the recipient's immune system, synthetic genomics can potentially increase the success rates of organ transplants and save more lives.
DNA printing, a rapidly evolving technology within synthetic genomics, allows for the precise and cost-effective synthesis of DNA sequences. This capability is fundamental for research and development across various fields, including medicine, agriculture, and industrial biotechnology. DNA printing enables scientists to quickly produce and test genetic constructs, accelerating the pace of innovation and discovery.
Synthetic genomics is revolutionizing the production of nutritional proteins and oils. Traditional agricultural methods are often limited by environmental factors and resource availability. Synthetic genomics provides a way to engineer organisms that can produce essential proteins and oils more efficiently and sustainably. This technology holds promise for addressing global nutritional needs and reducing the environmental impact of food production.
Global Synthetic Genomics Market, Segmentation by End User
The Global Synthetic Genomics Market has been segmented by End User into Biotechnology Companies, Pharmaceutical Companies, Academic Institutions, Government Laboratories and Contract Research Organizations.
Pharmaceutical companies also play a crucial role in the synthetic genomics market. They leverage these technologies to accelerate drug discovery and development processes, enabling the creation of more effective and personalized medicines. Synthetic genomics allows pharmaceutical firms to design and produce complex biological molecules, offering new avenues for tackling challenging diseases and improving patient outcomes.
Academic institutions are pivotal in advancing the field of synthetic genomics through fundamental research and innovation. Universities and research centers around the world are exploring the vast potential of synthetic biology, contributing to the knowledge base and developing new techniques and tools. These institutions often collaborate with industry partners to translate their findings into practical applications, fostering a dynamic ecosystem of discovery and development.
Government laboratories are also key players in the synthetic genomics market, focusing on national priorities such as biosecurity, environmental protection, and public health. These laboratories conduct critical research to address issues like emerging infectious diseases, environmental sustainability, and biological threats. Their work ensures that synthetic genomics technologies are developed and utilized in ways that benefit society and mitigate potential risks.
Contract research organizations (CROs) provide essential services that support the synthetic genomics market. These organizations offer expertise in various aspects of genomics research, from experimental design and execution to data analysis and interpretation. CROs enable biotechnology and pharmaceutical companies to outsource specific research activities, allowing them to focus on their core competencies and accelerate the development pipeline.
Global Synthetic Genomics Market, Segmentation by Geography
In this report, the Global Synthetic Genomics Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Synthetic Genomics Market Share (%), by Geographical Region, 2024
North America is expected to dominate the synthetic genomics market throughout the forecast period. The region's leadership can be attributed to the presence of a well-established biotechnology industry, substantial investment in research and development, and supportive regulatory frameworks. The United States, in particular, is a hub for synthetic genomics research, with numerous leading academic institutions and biotechnology companies driving innovation. The growing demand for personalized medicine and advancements in synthetic biology tools are further propelling market growth in this region.
Europe is also projected to hold a significant share of the synthetic genomics market. Countries like the United Kingdom, Germany, and France are at the forefront of synthetic genomics research, supported by robust government funding and collaborative efforts between research institutions and industry players. The European Union's focus on sustainability and environmental initiatives is fostering the adoption of synthetic genomics in areas such as biofuels and biodegradable materials. Additionally, Europe's regulatory environment, which emphasizes ethical considerations and biosafety, is shaping the market dynamics.
The Asia Pacific region is poised for rapid growth in the synthetic genomics market, driven by increasing investments in biotechnology and expanding research capabilities. Countries like China, Japan, and India are making significant strides in synthetic genomics, supported by government initiatives and rising private sector involvement. The region's large population base and growing demand for innovative healthcare solutions are stimulating market expansion. Furthermore, the application of synthetic genomics in agriculture to enhance crop yields and resilience is gaining momentum, addressing food security concerns in the region.
The Middle East and Africa region is gradually emerging as a potential market for synthetic genomics, with increasing awareness and adoption of advanced biotechnological solutions. While the region currently lags behind in terms of research infrastructure and investment compared to other regions, initiatives to develop biotechnology sectors and improve healthcare outcomes are creating new opportunities. Countries such as the United Arab Emirates and South Africa are beginning to explore the benefits of synthetic genomics in areas like healthcare and environmental sustainability.
Latin America is anticipated to witness moderate growth in the synthetic genomics market. Brazil and Argentina are leading the region in terms of research and development activities, particularly in agricultural biotechnology. The region's rich biodiversity presents unique opportunities for synthetic genomics applications in developing bio-based products and improving agricultural practices. Economic challenges and regulatory hurdles may pose constraints, but ongoing efforts to strengthen the biotechnology sector and attract foreign investments are likely to support market growth in the coming years.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Synthetic Genomics Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers
- Agricultural biotechnology
- Industrial biotechnology
- Sustainable solutions
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Renewable energy -The global synthetic genomics market is increasingly intertwined with the renewable energy sector, offering innovative solutions for sustainable energy production. Synthetic genomics technologies are revolutionizing the way renewable energy sources are produced, optimized, and utilized. This convergence is particularly evident in the development of biofuels, a key area where synthetic genomics is making significant strides. Synthetic genomics plays a pivotal role in biofuel production by engineering microorganisms to efficiently convert biomass into fuels such as ethanol, biodiesel, and bio-jet fuel. Through synthetic biology techniques, researchers can design and optimize microbial pathways for enhanced biomass degradation and biofuel synthesis. These engineered microorganisms exhibit improved traits such as higher substrate tolerance, increased productivity, and reduced production costs, making biofuels more economically viable and environmentally sustainable alternatives to fossil fuels.
Algae-based biofuels represent a promising avenue for renewable energy production, and synthetic genomics is driving advancements in this field. By manipulating the genetic makeup of algae strains, researchers can enhance lipid accumulation, biomass productivity, and overall lipid content, crucial factors for efficient biofuel production. Synthetic genomics enables the creation of designer algae with tailored traits optimized for biofuel synthesis, paving the way for scalable and cost-effective algal biofuel production. Synthetic genomics is facilitating the production of renewable chemicals from biomass-derived feedstocks. By engineering microorganisms to biosynthesize valuable chemicals and materials, such as bioplastics, biochemicals, and specialty chemicals, synthetic genomics enables the sustainable production of a wide range of industrial products. These renewable chemicals offer eco-friendly alternatives to petroleum-derived counterparts, contributing to the transition towards a bio-based economy and reducing reliance on finite fossil resources.
Synthetic genomics also holds promise for environmental remediation efforts, particularly in the cleanup of contaminated sites and the mitigation of pollution. Engineered microorganisms can be designed to metabolize and degrade pollutants, including hydrocarbons, heavy metals, and toxic chemicals, through tailored enzymatic pathways. By harnessing the power of synthetic biology, researchers can develop microbial strains with enhanced bioremediation capabilities, facilitating the restoration of ecosystems and mitigating environmental impacts associated with industrial activities.
Restraints
- High research and development costs
- Intellectual property issues
- Safety and biosecurity risks
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Limited public acceptance -Despite its promising potential, the global synthetic genomics market faces challenges stemming from limited public acceptance. This reluctance or skepticism from the public can be attributed to several factors. Ethical concerns surround the manipulation of genetic material. The ability to engineer or even create synthetic organisms raises questions about the implications for biodiversity, ecological balance, and potential unforeseen consequences in the environment. There are also ethical dilemmas regarding the creation of synthetic life forms and the ethical boundaries of genetic engineering.
Safety concerns loom large. The fear of unintended consequences or accidental release of engineered organisms into the environment creates apprehension among the public. Instances of genetic modifications gone awry in the past, whether in research or commercial settings, contribute to this skepticism. The perception of synthetic genomics as a complex and esoteric field can lead to misunderstandings and mistrust. The terminology and concepts involved in genetic engineering may be inaccessible to the general public, fostering a sense of unease or suspicion.
Societal and cultural factors play a role. Religious or cultural beliefs may conflict with certain applications of synthetic genomics, leading to resistance or opposition. Additionally, concerns about the commercialization of genetic resources and the unequal distribution of benefits exacerbate public skepticism. These challenges requires transparent communication, robust regulatory frameworks, and meaningful engagement with stakeholders. Efforts to educate the public about the benefits, risks, and ethical considerations of synthetic genomics are essential for building trust and fostering acceptance. Collaboration between scientists, policymakers, ethicists, and the public can help navigate the complexities of synthetic genomics responsibly and ethically, ensuring that its potential benefits are realized while minimizing its risks.
Opportunities
- Bio-based manufacturing
- Gene editing technologies
- Synthetic biology platforms
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Therapeutic applications -The therapeutic applications of synthetic genomics are at the forefront of medical innovation, offering promising solutions for a wide range of diseases and conditions. One of the most significant areas of focus is the development of innovative vaccines and therapeutics. Synthetic genomics enables researchers to design and engineer vaccines tailored to specific pathogens, including viruses, bacteria, and parasites. This targeted approach allows for the rapid development of vaccines to combat emerging infectious diseases and improve existing vaccination strategies. Synthetic genomics plays a crucial role in the development of personalized medicine. By analyzing individual genetic profiles, researchers can identify genetic factors contributing to diseases and tailor treatments to patients' specific genetic makeup. This approach holds immense potential for improving treatment outcomes and reducing adverse effects by optimizing therapies based on patients' genetic characteristics.
Another therapeutic application of synthetic genomics is in the field of gene therapy. Gene therapy involves introducing genetic material into cells to correct or replace defective genes associated with inherited disorders or acquired diseases. Synthetic genomics enables the design and synthesis of therapeutic DNA or RNA sequences for delivery into target cells, offering potential cures or long-term treatments for genetic disorders, cancer, and other diseases. Synthetic genomics is advancing regenerative medicine by facilitating the engineering of tissues and organs for transplantation. By combining synthetic biology techniques with tissue engineering approaches, researchers can create functional tissues and organs using bioengineered scaffolds seeded with patient-derived cells. This approach holds promise for overcoming the limitations of traditional organ transplantation, such as donor shortages and immune rejection, ultimately improving patient outcomes and quality of life.
These therapeutic applications, synthetic genomics is driving innovations in drug discovery and development. By designing synthetic DNA libraries encoding millions of unique compounds, researchers can rapidly screen for potential drug candidates against various targets, accelerating the drug discovery process and expanding the pharmacological toolbox for treating diseases. Overall, the therapeutic applications of synthetic genomics are revolutionizing healthcare by offering personalized, precise, and targeted treatments for a wide range of diseases and conditions. As research in synthetic genomics continues to advance, the potential for transformative breakthroughs in medicine remains high, paving the way for improved patient care and outcomes globally.
Competitive Landscape Analysis
Key players in Global Synthetic Genomics Market include.
- Synthetic Genomics Inc
- Ginkgo Bioworks
- Twist Bioscience
- DNA Script
- Codexis Inc
- Amyris Inc
- Intrexon Corporation (now part of Precigen Inc)
- Genomatica Inc
- Bluebird Bio Inc
- Arzeda
- Evolva
- TeselaGen Biotechnology
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Global Synthetic Genomics Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
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Agricultural biotechnology
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Industrial biotechnology
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Sustainable solutions
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Renewable energy
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- Restraints
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High research and development costs
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Intellectual property issues
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Safety and biosecurity risks
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Limited public acceptance
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- Opportunities
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Bio-based manufacturing
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Gene editing technologies
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Synthetic biology platforms
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Therapeutic applications
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Synthetic Genomics Market, By Product, 2021 - 2031 (USD Million)
- DNA Template
- Modifying Enzymes
- Adapters
- Primers
- Klenow Fragment
- Global Synthetic Genomics Market, By Application, 2021 - 2031 (USD Million)
- Innovative Vaccines & Therapeutics
- Bacterial Resistance
- Organ Transplantation
- DNA Printing
- Nutritional Proteins & Oils
- Global Synthetic Genomics Market, By End User, 2021 - 2031 (USD Million)
- Biotechnology Companies
- Pharmaceutical Companies
- Academic Institutions
- Government Laboratories
- Contract Research Organizations
- Global Synthetic Genomics Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Synthetic Genomics Market, By Product, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Synthetic Genomics Inc
- Ginkgo Bioworks
- Twist Bioscience
- DNA Script
- Codexis Inc
- Amyris Inc
- Intrexon Corporation (now part of Precigen Inc)
- Genomatica Inc
- Bluebird Bio Inc
- Arzeda
- Evolva
- TeselaGen Biotechnology
- Company Profiles
- Analyst Views
- Future Outlook of the Market