Global Surgical Sealants and Adhesives Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Type;
Natural or Biological Adhesives & Sealants [Fibrin Sealants, Collagen-Based Adhesives, and Gelatin-Based Adhesives], and Synthetic & Semi-Synthetic Adhesives & Sealants [Cyanoacrylates, Polymeric Hydrogels, and Urethane-Based Adhesives]By Application;
Central Nervous System, General Surgery, Orthopedic, Pulmonary, Urology, Ophthalmology, and OthersBy Indication;
Tissue Sealing, Tissue Engineering, and HemostasisBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Surgical Sealants and Adhesives Market Overview
Surgical Sealants and Adhesives Market (USD Million)
Surgical Sealants and Adhesives Market was valued at USD 2,723.80 million in the year 2024. The size of this market is expected to increase to USD 4,704.54 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 8.1%.
Global Surgical Sealants and Adhesives Market Growth, Share, Size, Trends and Forecast
*Market size in USD million
CAGR 8.1 %
Study Period | 2025 - 2031 |
---|---|
Base Year | 2024 |
CAGR (%) | 8.1 % |
Market Size (2024) | USD 2,723.80 Million |
Market Size (2031) | USD 4,704.54 Million |
Market Concentration | Medium |
Report Pages | 331 |
Major Players
- Baxter International, Inc
- CryoLife, Inc
- C.R. Bard, Inc
- Medtronic PLC
- B. Braun Melsungen AG
- Cohera Medical, Inc
- Ethicon, Inc
- Mallinckrodt PLC
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Global Surgical Sealants and Adhesives Market
Fragmented - Highly competitive market without dominant players
The surgical sealants and adhesives market is gaining momentum as healthcare providers increasingly adopt modern wound closure methods over traditional techniques like sutures and staples. These solutions offer quicker healing, lower infection risks, and better cosmetic results, making them ideal for a wide range of procedures. Currently, more than 50% of surgeries incorporate biocompatible adhesives to support enhanced patient outcomes.
Shift Toward Innovative Formulations
Healthcare professionals are showing a strong preference for synthetic and bio-based adhesives due to their durability, biocompatibility, and reduced immune response. These advanced formulations now contribute to around 60% of the overall product usage in surgical environments. Their versatility allows customization for various surgical needs, encouraging continuous development and broader clinical use.
Expanding Use Across Multiple Specialties
The utility of surgical sealants and adhesives is expanding beyond general surgeries to include orthopedic, neurosurgical, and cardiovascular procedures. Their ability to seal tissues, control bleeding, and minimize complications makes them essential in more than 65% of high-risk surgeries. Their adaptability supports surgeons in achieving optimal outcomes in complex clinical scenarios.
Technological Enhancements Driving Market Growth
Recent progress in adhesive technologies and polymer science has significantly improved the performance and usability of surgical adhesives. Modern products offer faster application, stronger bonding strength, and flexibility for dynamic tissues. Notably, over 40% of product innovations focus on extended shelf life and application efficiency, simplifying workflow for surgical teams.
Surgical Sealants and Adhesives Market Recent Developments
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In November 2023, Pramand LLC launched the CraniSeal Dural Sealant System in the U.S. market, designed for use in cranial surgery.
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In November 2023, Ethicon, a division of Johnson & Johnson's MedTech, launched Ethizia, a hemostatic sealing patch designed to control bleeding during surgeries.
Surgical Sealants and Adhesives Market Segment Analysis
In this report, the Surgical Sealants and Adhesives Market has been segmented by Type, Indication, Application, and Geography.
Surgical Sealants and Adhesives Market, Segmentation by Type
The Surgical Sealants and Adhesives Market has been segmented by Type into Natural or biological adhesives and sealants and Synthetic and Semi Synthetic Adhesives and Sealants.
Natural or Biological Adhesives and Sealants
Natural or biological adhesives and sealants account for approximately 55% of the market. These include fibrin sealants and collagen-based adhesives, widely used for hemostasis and wound closure in various surgeries. Their biocompatibility and effective tissue adhesion drive strong growth.
Synthetic and Semi-Synthetic Adhesives and Sealants
Synthetic and semi-synthetic adhesives and sealants represent about 45% of the market. These products, including cyanoacrylates and polyethylene glycol-based sealants, offer strong bonding strength and versatility. Their ability to handle high-tension wounds and provide rapid sealing supports growth.
Surgical Sealants and Adhesives Market, Segmentation by Indication
The Surgical Sealants and Adhesives Market has been segmented by Indication intoTissue Sealing, Tissue Engineering, Hemostasis.
Tissue Sealing
Tissue sealing accounts for approximately 60% of the surgical sealants and adhesives market. These products provide effective closure of tissue surfaces, reducing leakage and infection risks. Increasing use in gastrointestinal, pulmonary, and vascular surgeries supports growth.
Tissue Engineering
Tissue engineering represents around 25% of the market, with sealants and adhesives playing a key role in regenerative medicine. These products support scaffold integration and cell adhesion for tissue repair. Rising focus on biomedical innovations and customized tissue regeneration drives this segment.
Hemostasis
Hemostasis contributes about 15% of the market, with adhesives and sealants ensuring rapid bleeding control during surgery. Their ability to reduce blood loss and minimize transfusions makes them essential in trauma and high-risk procedures. Technological advancements support sustained growth.
Surgical Sealants and Adhesives Market, Segmentation by Application
The Surgical Sealants and Adhesives Market has been segmented by Application into Central nervous system, General surgery, Orthopedic, Pulmonary, Urology, Ophthalmology and Others.
Central Nervous System
Central nervous system applications account for approximately 20% of the market, focusing on cranial and spinal surgeries. Adhesives and sealants improve leak prevention and reduce infection risk in these high-risk procedures, driving adoption in neurosurgical settings.
General Surgery
General surgery holds about 25% of the market, with sealants and adhesives supporting wound closure, tissue sealing, and bleeding control. Increasing focus on minimally invasive procedures and infection prevention supports growth in this segment.
Orthopedic
Orthopedic applications represent around 15% of the market, leveraging adhesives and sealants for fracture repair, bone grafting, and joint reconstruction. Their ability to enhance biomechanical stability and tissue integration supports adoption.
Pulmonary
Pulmonary surgeries account for approximately 10% of the market, using adhesives and sealants to prevent air leaks and promote tissue healing. Increasing demand for lung surgeries and minimally invasive techniques drives growth.
Urology
Urology represents around 10% of the market, with sealants and adhesives supporting prostate, bladder, and kidney surgeries. Their role in reducing bleeding and enhancing tissue closure drives adoption.
Ophthalmology
Ophthalmology contributes about 10% of the market, utilizing adhesives and sealants in corneal, retinal, and cataract surgeries. Their biocompatibility and precision application support increasing use in ocular procedures.
Others
The ‘Others’ category, including dermatology and plastic surgery, holds around 10% of the market. Ongoing technological advancements and expanding use of sealants and adhesives in diverse surgical procedures drive this segment’s growth.
Surgical Sealants and Adhesives Market, Segmentation by Geography
In this report, the Surgical Sealants and Adhesives Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Surgical Sealants and Adhesives Market Share (%), by Geographical Region
North America
North America holds approximately 40% of the surgical sealants and adhesives market, driven by advanced healthcare systems, high adoption of innovative technologies, and increasing demand for minimally invasive procedures. Continuous product innovation and strong regulatory frameworks support market growth.
Europe
Europe accounts for about 30% of the market, supported by a strong regulatory environment and a focus on high-quality patient care. Increasing adoption of advanced surgical materials and growing elective surgery volumes drive expansion in this region.
Asia Pacific
Asia Pacific represents approximately 20% of the market, witnessing rapid growth fueled by expanding healthcare infrastructure, rising medical investments, and increasing procedural volumes. Countries such as China and India play key roles with growing technology adoption.
Middle East and Africa
Middle East and Africa contribute around 5% of the market, with growth supported by government healthcare initiatives and rising hospital capacity. Increased demand for advanced wound care solutions and emphasis on infection control fuel adoption.
Latin America
Latin America holds about 5% of the market, led by countries such as Brazil and Mexico. Expanding healthcare access, increasing procedure volumes, and growing adoption of innovative surgical solutions drive growth in this region.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Surgical Sealants and Adhesives Market. These factors include; Market Drivers, Restraints and Opportunities.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces—Drivers, Restraints, and Opportunities—affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
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Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development |
Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers, Restraints and Opportunity Analysis
Drivers:
- Advancements in Surgical Techniques
- Focus on Patient Safety and Faster Recovery
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Rising Incidence of Chronic Diseases - The rising global burden of chronic diseases such as cardiovascular disorders, diabetes, and cancer is a key driver for the surgical sealants and adhesives market. These conditions often necessitate surgical interventions, including open-heart procedures, tumor resections, and organ repairs, where effective wound closure and hemostasis are critical. Surgical sealants and adhesives provide faster sealing, minimize blood loss, and reduce the risk of post-operative complications, making them increasingly essential in managing chronic disease-related surgeries.
As the number of patients requiring surgery continues to rise, especially among aging populations, there is growing demand for advanced closure technologies that enhance healing and reduce hospital stay durations. Minimally invasive procedures are also becoming more common, further fueling the need for versatile, biocompatible sealants and adhesives that can function in complex anatomical environments. This shift toward safer, more efficient surgical solutions strongly supports the expansion of this market across diverse clinical specialties.
Restraints:
- High Cost of Advanced Sealants and Adhesives
- Concerns Regarding Product Efficacy and Safety
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Limited Reimbursement Coverage - Limited reimbursement coverage remains a major restraint for the surgical sealants and adhesives market, particularly in developing economies and certain healthcare systems with cost-containment policies. Despite their proven clinical benefits in enhancing surgical outcomes and reducing complications, many advanced sealants and adhesives are not fully covered under insurance plans or public health reimbursement schemes. This lack of coverage often shifts the financial burden to hospitals or patients, discouraging widespread adoption, especially in resource-constrained settings.
The reimbursement gap becomes more pronounced for newer, high-performance products that offer enhanced efficacy but come at a premium cost. Without proper coding, classification, or inclusion in reimbursement policies, these products face delays in market penetration. Healthcare providers may also be reluctant to adopt them over conventional closure techniques if financial support is lacking. Addressing these limitations through updated reimbursement frameworks is essential for driving broader usage and maximizing the market potential of surgical sealants and adhesives.
Opportunities:
- Expanding Applications in Specialized Surgeries
- Strategic Partnerships and Collaborations
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Focus on Product Differentiation and Innovation - The growing emphasis on product differentiation and innovation is opening substantial opportunities within the surgical sealants and adhesives market. As surgical procedures become more specialized and patient-specific, the need for tailored wound closure solutions has increased. Manufacturers are focusing on developing products with enhanced properties such as faster adhesion, biodegradability, tissue compatibility, and antimicrobial capabilities. These advancements allow products to address varied clinical demands across different types of surgeries, including cardiovascular, neurological, orthopedic, and reconstructive procedures.
Innovations in synthetic polymers, natural biomaterials, and nanotechnology are helping companies differentiate their offerings in a competitive landscape. Customizing formulations to improve elasticity, reduce toxicity, or provide targeted delivery of therapeutic agents further expands product utility. Such differentiation not only enhances surgical efficiency but also contributes to faster healing and reduced post-operative complications, aligning with healthcare systems’ goals for improved patient outcomes.
Companies investing in next-generation adhesives that can function effectively in wet environments, bond to dynamic tissues, or replace traditional sutures altogether are likely to capture emerging market segments. These efforts support the ongoing shift toward minimally invasive surgeries and value-based care models that prioritize speed, safety, and cost-effectiveness. As healthcare providers continue to seek superior alternatives to conventional closure techniques, the market rewards innovation that delivers both clinical and economic advantages.
Competitive Landscape Analysis
Key players in Global Surgical Sealants and Adhesives Market include:
- Baxter International, Inc
- CryoLife, Inc
- C.R. Bard, Inc
- Medtronic PLC
- B. Braun Melsungen AG
- Cohera Medical, Inc
- Ethicon, Inc
- Mallinckrodt PLC
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Market Share Analysis
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Application
- Market Snapshot, By Indication
- Market Snapshot, By Region
- Global Surgical Sealants and Adhesives Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Advancements in Surgical Techniques
- Focus on Patient Safety and Faster Recovery
- Rising Incidence of Chronic Diseases
- Restraints
- High Cost of Advanced Sealants and Adhesives
- Concerns Regarding Product Efficacy and Safety
- Limited Reimbursement Coverage
- Opportunities
- Expanding Applications in Specialized Surgeries
- Strategic Partnerships and Collaborations
- Focus on Product Differentiation and Innovation
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Surgical Sealants and Adhesives Market, By Type, 2021 - 2031 (USD Million)
- Natural or biological adhesives and sealants
- Fibrin Sealants
- Collagen Based Adhesives
- Gelatin Based Adhesives
- Synthetic and Semi Synthetic Adhesives and Sealants
- Cyanoacrylates
- Polymeric Hydrogels
- Urethane Based Adhesives
- Natural or biological adhesives and sealants
- Global Surgical Sealants and Adhesives Market, By Application, 2021 - 2031 (USD Million)
- Central nervous system
- General surgery
- Orthopedic
- Pulmonary
- Urology
- Ophthalmology
- Others
- Global Surgical Sealants and Adhesives Market, By Indication, 2021 - 2031 (USD Million)
- Tissue Sealing
- Tissue Engineering
- Hemostasis
- Global Surgical Sealants and Adhesives Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Surgical Sealants and Adhesives Market, By Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Baxter International, Inc
- CryoLife, Inc
- C.R. Bard, Inc
- Medtronic PLC
- B. Braun Melsungen AG
- Cohera Medical, Inc
- Ethicon, Inc
- Mallinckrodt PLC
- Company Profiles
- Analyst Views
- Future Outlook of the Market