Surgical Hemostats, Internal Tissue Sealants, And Adhesion Barriers Market
By Product Type;
Hemostats - [Thrombin Based, Combination Hemostats, Oxidized Regenerated Cellulose Based, Gelatin Based, and Collagen Based], Internal Tissue Sealants - [Fibrin Based, Collagen Based, Protein Based, and Synthetic Polymer Based], and Adhesion Barriers - [Film Based, Gel Based, and Solution Based]By Application;
Surgical Applications - [Cardiovascular Surgeries, Neurological Surgeries, Orthopedic Surgeries, Urological & Gynecological Surgeries, General Surgeries, Reconstructive & Plastic Surgeries, and Others] and Trauma CasesBy End User;
Hospitals, Ambulatory Surgical Centers, and Specialty ClinicsBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market Overview
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market (USD Million)
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market was valued at USD 8,079.20 million in the year 2024. The size of this market is expected to increase to USD 26,540.56 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 18.5%.
Surgical Hemostats, Internal Tissue Sealants, And Adhesion Barriers Market
*Market size in USD million
CAGR 18.5 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 18.5 % |
Market Size (2024) | USD 8,079.20 Million |
Market Size (2031) | USD 26,540.56 Million |
Market Concentration | Low |
Report Pages | 324 |
Major Players
- Ethicon (Johnson & Johnson)
- Baxter International Inc.
- Integra LifeSciences Holdings Corporation
- Pfizer Inc.
- Tissuemed Ltd.
- Sanofi
- Braun Melsungen AG
- C.R. Bard, Inc.
- CryoLife, Inc.
- Cohera Medical
- CSL Behring
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Surgical Hemostats, Internal Tissue Sealants, And Adhesion Barriers Market
Fragmented - Highly competitive market without dominant players
The Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market is witnessing accelerated momentum with increasing adoption of minimally invasive surgical procedures. Over 60% of surgical interventions now rely on advanced hemostatic and sealing solutions to improve post-operative outcomes. The focus on reducing procedural time and enhancing patient recovery is further pushing demand for these innovative medical materials. This market continues to offer strategic opportunities through innovation and technology-driven growth.
Rising Demand for Enhanced Surgical Safety
As awareness around surgical safety and post-operative complications grows, the need for adhesion barriers and tissue sealants is also rising. More than 55% of surgeries involving abdominal or pelvic cavities utilize barrier-based solutions to avoid internal adhesions. This has led to increased collaboration between hospitals and biotech innovators for safer procedures. Continued advancements in bio-compatible materials are driving further market expansion.
Innovation and Technological Advancements
Ongoing technological advancements are reshaping how internal tissue sealants and hemostats function across diverse surgical environments. Over 58% of next-generation products now incorporate bioresorbable compounds or synthetic polymers to improve effectiveness and reduce immune response. These innovations are resulting in faster approvals and higher adoption among healthcare professionals, fueling future market growth.
Outlook for Growth and Expansion
The future outlook of the Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market is positive, driven by the increasing emphasis on post-operative recovery quality and procedure efficiency. With more than 65% of healthcare institutions integrating advanced wound care protocols, the market is set for sustained growth. Investments in research and development are expected to further enhance the performance and accessibility of these products across surgical disciplines.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market Recent Developments
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In November 2021, according to an article published by the Journal of Coloproctology, a study was performed at Department of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan to check the use of an absorbable adhesion barrier made of oxidized regenerated cellulose (INTERCEED) for temporary diverting ileostomy in minimally invasive rectal surgery. The study was performed on 36 patients who underwent ileostomy. The degree of adhesion formation between the ileal limbs and the rectus abdominis muscles, operating time, and estimated blood loss were significantly reduced in patients treated with INTERCEED compared with those treated by the conventional approach. There were no postoperative complications observed. Hence, use of INTERCEED for diverting ileostomy can contribute to reduced adhesion formation.
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In October 2021, Toray Industries Inc., a Japan-based manufacturer of medical devices, and ASKA Pharmaceuticals Co. Ltd., a Japan based pharmaceutical company, announced that they had signed a business collaboration agreement to develop and commercialize an adhesion barrier in Japan. Toray and ASKA jointly developed the product to obtain marketing approval of the product in Japan. According to this agreement, Toray manufactured the Product, as ASKA got exclusive market for the Product in Japan.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market Segment Analysis
In this report, the Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market has been segmented by Product Type, Application, End User, and Geography.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, Segmentation by Product Type
The Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market has been segmented by Product Type into Hemostats, Internal Tissue Sealants, and Adhesion Barriers.
Hemostats
Hemostats dominate the market with a share of approximately 48%, due to their critical role in controlling bleeding during surgical procedures. Their rapid action and ease of use drive high adoption across a variety of surgical settings.
Internal Tissue Sealants
Internal tissue sealants account for nearly 33% of the market, offering effective wound closure and minimizing postoperative complications. The increasing preference for minimally invasive surgeries fuels demand in this segment.
Adhesion Barriers
Adhesion barriers contribute around 19% to the overall market, helping to prevent post-surgical adhesions that may lead to further complications. Growth is supported by rising awareness of their long-term benefits among surgeons.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, Segmentation by Application
The Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market has been segmented by Application into Surgical Applications and Trauma Cases.
Surgical Applications
Surgical applications represent the largest share of the market, accounting for nearly 72%, driven by the rising volume of elective and emergency surgeries. The demand is fueled by the need for effective bleeding control and post-operative healing support across general, orthopedic, and cardiovascular surgeries.
Trauma Cases
Trauma cases contribute around 28% of the market, supported by the increasing incidence of accidents and injuries requiring immediate medical intervention. Rapid product deployment and enhanced patient outcomes make these solutions vital in emergency care settings.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, Segmentation by End User
The Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market has been segmented by End User into Hospitals, Ambulatory Surgical Centers, and Specialty Clinics.
Hospitals
Hospitals dominate the market, contributing nearly 64% of the total share, due to the high volume of complex surgeries and extensive use of hemostats and sealants in critical care units. Their access to advanced surgical infrastructure supports strong product uptake.
Ambulatory Surgical Centers
Ambulatory surgical centers account for approximately 22% of the market, driven by the rising trend of outpatient surgeries. These centers benefit from shorter patient stays and efficient procedure turnover, supporting cost-effective adoption.
Specialty Clinics
Specialty clinics contribute around 14%, focusing on niche procedures such as dermatologic or gynecologic surgeries. Though smaller in scale, they show steady demand due to increasing patient preference for specialized care environments.
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, Segmentation by Geography
In this report, the Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Regions and Countries Analyzed in this Report
Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market Share (%), by Geographical Region
North America
North America holds the largest market share at approximately 38%, owing to its advanced healthcare infrastructure and strong adoption of surgical innovations. High healthcare spending and increasing surgical volumes further support market growth.
Europe
Europe contributes around 27% of the market, driven by an aging population and a steady rise in elective surgeries. Favorable reimbursement policies and presence of key manufacturers strengthen its position.
Asia Pacific
Asia Pacific is the fastest-growing region, expanding at over 9% CAGR, fueled by rising medical tourism and improving surgical capabilities in countries like India, China, and Japan. Government initiatives are also boosting regional demand.
Middle East & Africa
The Middle East & Africa region represents a smaller share of around 5%, but is experiencing growth due to healthcare investments in Gulf nations and increasing awareness of surgical technologies in Africa.
Latin America
Latin America accounts for nearly 6% of the market, supported by expanding hospital networks and rising healthcare expenditures in countries like Brazil and Mexico. However, challenges in regulatory frameworks may limit rapid growth.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers
- Surgical Demand
- Patient Safety
- Technological Innovation
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Healthcare Infrastructure - Healthcare infrastructure forms the backbone of any healthcare system, encompassing a wide range of physical and organizational assets essential for delivering healthcare services to individuals and communities. Physical infrastructure includes hospitals, clinics, diagnostic facilities, and medical equipment, while organizational infrastructure comprises healthcare policies, financing mechanisms, workforce capacity, and information systems. A robust healthcare infrastructure is crucial for ensuring access to quality healthcare services, promoting health outcomes, and addressing the healthcare needs of diverse populations.
In developed countries, healthcare infrastructure tends to be more comprehensive and sophisticated, with well-equipped hospitals, advanced medical technologies, and extensive healthcare networks. These countries often have universal healthcare systems or comprehensive health insurance coverage, ensuring access to healthcare services for all residents. Moreover, investments in healthcare infrastructure are prioritized, with a focus on upgrading facilities, expanding healthcare services, and adopting innovative technologies to improve patient care and outcomes.
In contrast, many developing countries face significant challenges in healthcare infrastructure, including limited access to healthcare facilities, shortages of medical supplies and trained healthcare professionals, and inadequate healthcare financing mechanisms. Addressing these challenges requires sustained investments in healthcare infrastructure, capacity building, and health system strengthening initiatives. Additionally, leveraging digital technologies and telemedicine can help bridge gaps in healthcare access and delivery, particularly in remote and underserved areas. Overall, strengthening healthcare infrastructure is essential for achieving universal health coverage, promoting health equity, and advancing global health goals.
Restraints
- Regulatory Hurdles
- Safety Concerns
- High Costs
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Limited Reimbursement - Limited reimbursement refers to constraints or restrictions placed on the amount or type of payment that healthcare providers receive for delivering healthcare services or products. This limitation can have significant implications for healthcare providers, patients, and the healthcare industry as a whole.
For healthcare providers, limited reimbursement can impact their financial sustainability and ability to invest in resources, infrastructure, and staff. When reimbursement rates are insufficient to cover the costs of providing care, healthcare providers may face financial strain, leading to reduced access to services, workforce shortages, and compromised quality of care. Additionally, limited reimbursement may disincentivize providers from offering certain services or investing in new technologies or treatments that may improve patient outcomes but are not adequately reimbursed.
For patients, limited reimbursement can result in out-of-pocket expenses, reduced access to needed healthcare services, and financial hardship. Patients may face higher copayments, deductibles, or uncovered services, particularly for treatments or procedures deemed to have limited reimbursement. This can create barriers to accessing care, especially for vulnerable populations or those with limited financial resources, leading to disparities in healthcare access and outcomes.
For the healthcare industry, limited reimbursement can impact innovation, research, and development efforts. If reimbursement rates do not adequately compensate for the costs of developing new drugs, medical devices, or technologies, companies may be less incentivized to invest in innovation or bring new products to market. This can stifle progress in healthcare advancements and limit the availability of innovative treatments or interventions that could improve patient outcomes and quality of life.
Opportunities
- Emerging Markets
- Advanced Technologies
- Aging Population
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Minimally Invasive Surgery - Minimally invasive surgery (MIS) represents a paradigm shift in surgical practice, offering patients less invasive alternatives to traditional open surgeries. This approach utilizes advanced surgical techniques and technologies to perform procedures through small incisions, often with the aid of specialized instruments and imaging guidance. Minimally invasive surgery encompasses a wide range of surgical specialties, including general surgery, gynecology, urology, orthopedics, and cardiothoracic surgery.
One of the key benefits of minimally invasive surgery is reduced trauma to surrounding tissues and organs compared to traditional open surgeries. By utilizing smaller incisions, MIS minimizes blood loss, post-operative pain, and recovery time, leading to shorter hospital stays and faster return to normal activities for patients. Moreover, the cosmetic outcomes of MIS are often superior, with smaller scars and less visible surgical wounds compared to open surgeries.
Advancements in surgical technology have greatly expanded the scope of minimally invasive surgery, enabling surgeons to perform increasingly complex procedures with precision and safety. Techniques such as laparoscopy, robotic-assisted surgery, and endoscopy have revolutionized surgical practice, allowing surgeons to access and visualize internal structures with greater clarity and dexterity. Additionally, innovations in imaging modalities, such as intraoperative ultrasound and fluoroscopy, enhance procedural accuracy and patient safety during MIS.
Competitive Landscape Analysis
Key players in Global Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market include;
- Ethicon (Johnson & Johnson)
- Baxter International Inc.
- Integra LifeSciences Holdings Corporation
- Pfizer Inc.
- Tissuemed Ltd.
- Sanofi
- Braun Melsungen AG
- C.R. Bard, Inc.
- CryoLife, Inc.
- Cohera Medical
- CSL Behring
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product Type
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Surgical Demand
- Patient Safety
- Technological Innovation
- Healthcare Infrastructure
- Restraints
- Regulatory Hurdles
- Safety Concerns
- High Costs
- Limited Reimbursement
- Opportunities
- Emerging Markets
- Advanced Technologies
- Aging Population
- Minimally Invasive Surgery
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, By Product Type, 2021 - 2031 (USD Million)
- Hemostats
- Thrombin Based
- Combination Hemostats
- Oxidized Regenerated Cellulose Based
- Gelatin Based
- Collagen Based
- Internal Tissue Sealants
- Fibrin Based
- Collagen Based
- Protein Based
- Synthetic Polymer Based
- Adhesion Barriers
- Film Based
- Gel Based
- Solution Based
- Hemostats
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market,By Application, 2021 - 2031 (USD Million)
- Surgical Applications
- Neurological Surgeries
- Orthopedic Surgeries
- Urological & Gynecological Surgeries
- General Surgeries
- Reconstructive and Plastic Surgeries
- Others
- Trauma Cases
- Surgical Applications
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, By End User, 2021 - 2031 (USD Million)
- Hospitals
- Ambulatory Surgical Centers
- Specialty Clinics
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market, By Product Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Ethicon (Johnson & Johnson)
- Baxter International Inc.
- Integra LifeSciences Holdings Corporation
- Pfizer Inc.
- Tissuemed Ltd.
- Sanofi
- Braun Melsungen AG
- C.R. Bard, Inc.
- CryoLife, Inc.
- Cohera Medical
- CSL Behring
- Company Profiles
- Analyst Views
- Future Outlook of the Market