Surgical Glue Market
By End-User;
Hospitals, Ambulatory Surgical Centers and OthersBy Product;
Natural and Synthetic & Semi-SyntheticBy Application;
Central Nervous System Surgeries, General Surgeries, Cardiovascular Surgeries, Orthopedic Surgeries, Cosmetic Surgeries, Ophthalmic Surgeries, Urological Surgeries, Pulmonary Surgeries and OthersBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Surgical Glue Market Overview
Surgical Glue Market (USD Million)
Surgical Glue Market was valued at USD 2,509.44 million in the year 2024. The size of this market is expected to increase to USD 3,760.83 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 6.0%.
Surgical Glue Market
*Market size in USD million
CAGR 6.0 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 6.0 % |
Market Size (2024) | USD 2,509.44 Million |
Market Size (2031) | USD 3,760.83 Million |
Market Concentration | Medium |
Report Pages | 314 |
Major Players
- Baxter
- B. Braun Melsungen AG
- Cardinal Health
- CR. Bard
- Johnson and Johnson
- OptMed, Inc
- Applied Medical Resources Corporation
- CryoLife
- Integra LifeSciences
- Medtronic
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Surgical Glue Market
Fragmented - Highly competitive market without dominant players
The Surgical Glue Market is witnessing strong growth as medical facilities increasingly adopt tissue adhesives for wound closure and internal procedures. Nearly 55% of hospitals now use surgical glues as an alternative to sutures and staples due to their faster application and reduced scarring. Their role in improving patient recovery and lowering infection risks is driving widespread demand.
Preference for Minimally Invasive Solutions
The shift toward minimally invasive procedures has accelerated the adoption of surgical glues. Around 60% of surgical interventions today employ adhesives for sealing tissues, particularly in delicate surgeries. Their ability to provide secure closure without additional trauma makes them a preferred choice in modern healthcare.
Technological Advancements in Formulations
Innovations in biocompatible and bioresorbable glues are enhancing market growth. Nearly 45% of new product developments emphasize advanced formulations that improve bonding strength while reducing toxicity. These innovations are increasingly being tailored to specialized applications such as cardiovascular, orthopedic, and cosmetic surgeries.
Focus on Patient Outcomes and Safety
Surgical glues significantly contribute to reduced post-operative complications. Studies indicate that their use can lower wound infection rates by almost 35%, improving patient safety. Additionally, they shorten recovery time and minimize discomfort, reinforcing their role in delivering efficient and patient-friendly care.
Future Potential of the Market
With rising demand for next-generation wound closure technologies, the surgical glue market is set for substantial expansion. More than 50% of ongoing clinical studies in surgical innovations are focused on adhesive-based solutions, underlining their growing importance in shaping the future of medical procedures.
Surgical Glue Market Recent Developments
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January 2022, Chemence Medical, Inc., received Food and Drug Administration clearance to market and sell the Exofin Precision Pen as a new medical device for wound closure. The Exofin Precision Pen will enable medical providers greater versatility and exactness in closing wounds while also improving ease of use in applying topical skin adhesive.
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January 2022, Futura Surgicare Pvt Ltd, developed devices on wound closure operating with brands like Dolphin Sutures, Dolphin Mesh, Dolphin Tapes, Dolphin Hemostat and Dolphin Stapler.
Surgical Glue Market Segment Analysis
The Surgical Face Masks Market Has Been Segmented By Product, Indication, Application, End User and Geography.
Surgical Glue Market, Segmentation by Product
The Surgical Face Masks Market Has Been Segmented By Product into Natural Adhesives & Sealants - Fibrin Sealants , Collagen-based Adhesives & Gelatin-based Adhesives, Synthetic & Semi-synthetic Adhesives & Sealants - Cyanoacrylates , Hydrogels and Polyurethane-based Adhesives.
Fibrin Sealants
Fibrin formulations are valued for biocompatibility, rapid hemostasis, and natural tissue adhesion, supporting gentle sealing in delicate procedures. Adoption often reaches a high-single-digit % of hospital usage where biologics are preferred. Demand rises with minimally invasive surgery and enhanced recovery protocols, strengthening premium mix and clinician preference
Collagen-based Adhesives
Collagen matrices provide scaffold support, controlled absorption, and wound stabilization across ENT, dental, and general surgery. Utilization typically holds a mid-single-digit % share where biologic dressings are reimbursed. Ongoing shifts to tissue-friendly closure and reduced suture time sustain steady % growth in specialty centers
Gelatin-based Adhesives
Gelatin sealants enable fluid management, localized hemostasis, and ease of handling for broad intraoperative use. Penetration commonly registers a low-double-digit % in high-volume procedures demanding quick seal. Preference improves with ready-to-use formats and shorter OR time, supporting incremental % gains in ambulatory settings
Cyanoacrylates
Medical-grade cyanoacrylates deliver fast polymerization, strong tensile bond, and barrier protection for skin closure and minor lacerations. Outpatient adoption often sits in a low-double-digit % where stitch alternatives are prioritized. Growth is reinforced by infection control needs and cost-efficient closures that trim follow-up rates by a measurable %
Hydrogels
Hydrogel systems offer moist wound healing, atraumatic removal, and drug-loading potential, aiding complex incision management. Share typically tracks at a mid-single-digit %, expanding with advanced dressings and minimally invasive workflows. Increasing focus on patient comfort and reduced adhesions supports sustainable % growth
Polyurethane-based Adhesives
Polyurethane chemistries provide durable bonding, flexibility, and chemical resistance suited to device assembly and select closures. Usage often accounts for a high-single-digit % in facilities emphasizing long-wear films and barrier performance. Broader adoption follows scalable manufacturing and cost-effectiveness, contributing to steady % increases
Surgical Glue Market, Segmentation by Indication
The Surgical Face Masks Market Has Been Segmented By Indication into Hemostasis and Tissue Sealing.
Hemostasis
Hospitals use hemostatic indications to achieve rapid blood control, stable clot formation, and lower transfusion risk during procedures. Utilization commonly reaches a low-double-digit % across high-volume surgeries. Adoption rises with minimally invasive techniques, enhanced recovery protocols, and measured % gains in outpatient workflows
Tissue Sealing
Tissue sealing supports airtight closure, leak prevention, and reduced postoperative complications in complex cases. Share often records a mid-single-digit %, expanding with advanced wound care and biocompatible materials. Preference strengthens as facilities target measurable % reductions in OR time and readmissions
Surgical Glue Market, Segmentation by Application
The Surgical Face Masks Market Has Been Segmented By Application into Cardiovascular Surgery, Plastic Surgery, Liver & Spleen Laceration, Orthopedic Surgery, Burn Bleeding, Wound management, General Surgery and Others.
Cardiovascular Surgery
In cardiovascular procedures, adhesives and sealants are used for precise hemostasis, vascular repair, and reduced blood loss. Adoption often holds a mid-single-digit % share, driven by complex bypass operations and minimally invasive cardiac techniques that demand reliable closure solutions.
Plastic Surgery
Plastic surgery applications focus on scar minimization, delicate tissue adhesion, and improved aesthetic outcomes. Utilization typically maintains a low-double-digit %, supported by the rising volume of cosmetic enhancements and reconstructive procedures requiring atraumatic sealing.
Liver & Spleen Laceration
For trauma-related liver and spleen injuries, products enable rapid bleeding control, organ preservation, and reduced mortality risk. Usage often represents a mid-single-digit %, especially in emergency surgical units where quick hemostatic action is critical.
Orthopedic Surgery
Orthopedic interventions utilize adhesives for bone graft stabilization, joint repair, and postoperative bleeding reduction. Share typically stands in a high-single-digit %, with growth supported by increased fracture treatments and joint replacement procedures.
Burn Bleeding
In burn care, these products assist with capillary sealing, wound stabilization, and infection prevention. Adoption is often in the low-single-digit %, rising as burn management centers expand advanced wound closure protocols.
Wound Management
Wound management applications rely on moist healing environments, reduced dressing changes, and minimized scar formation. Share frequently records a low-double-digit %, supported by chronic wound therapies and outpatient care programs.
General Surgery
In general surgical cases, adhesives are used for tissue approximation, bleeding control, and shortened recovery times. Utilization often reaches a mid-single-digit %, expanding with the adoption of enhanced recovery protocols.
Others
This category includes specialized and rare indications that require customized adhesion solutions. While share remains minimal, targeted innovations and niche procedural growth continue to expand opportunities.
Surgical Glue Market, Segmentation by End User
The Surgical Face Masks Market Has Been Segmented By End User into Hospitals, Ambulatory surgical centers and Specialty Clinics.
Hospitals
Hospitals represent the largest user base, utilizing products for complex surgeries, emergency care, and inpatient treatments. Adoption frequently exceeds a high-single-digit %, driven by high surgical volumes and integrated infection control protocols that demand reliable closure and sealing solutions.
Ambulatory Surgical Centers
Ambulatory surgical centers focus on day-care procedures, minimally invasive surgeries, and cost-efficient workflows. Utilization often holds a mid-single-digit % share, supported by the shift toward same-day discharge and reduced hospitalization costs.
Specialty Clinics
Specialty clinics apply these products in focused treatment areas such as cosmetic, orthopedic, or ophthalmic care. Share typically remains in the low-single-digit %, expanding with the growth of specialized surgical practices and targeted patient services.
Surgical Glue Market, Segmentation by Geography
The Surgical Face Masks Market Has Been Segmented By Geography into five regions; North America, Europe, Asia Pacific, Middle East & Africa, and, Latin America.
Regions and Countries Analyzed in this Report
Surgical Glue Market Share (%), by Geographical Region
North America
North America holds a significant share due to advanced healthcare infrastructure, high surgical volumes, and stringent safety standards. Adoption rates often exceed a mid-double-digit %, supported by strong reimbursement frameworks and the widespread use of innovative surgical materials.
Europe
Europe demonstrates steady growth, driven by government healthcare funding, rising surgical procedures, and stringent quality regulations. Utilization commonly stands at a mid-single-digit %, with expansion fueled by minimally invasive surgery adoption and infection control initiatives.
Asia Pacific
Asia Pacific experiences robust growth supported by expanding healthcare access, increasing medical tourism, and rising disposable incomes. Market share often records a high-single-digit %, with rapid adoption in emerging economies and urban healthcare facilities.
Middle East & Africa
The Middle East & Africa region is gradually expanding, driven by improving hospital infrastructure, government investments, and growing surgical demand. Utilization usually falls in the low-single-digit %, with opportunities arising from private healthcare sector growth.
Latin America
Latin America shows moderate growth fueled by public health initiatives, rising surgical awareness, and expanding private healthcare. Adoption is generally in the low-single-digit %, with a boost from regional manufacturing capabilities and cost-competitive products.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Surgical Glue Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers:
- Growth in Elective Surgeries
- Rising Number of Surgical Procedures
- Increasing Incidence of Trauma and Accidents
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Innovations and Improvements in Adhesive Materials: In recent years, the global surgical glue market has witnessed remarkable innovations and improvements in adhesive materials, revolutionizing surgical procedures and patient outcomes. One notable advancement lies in the development of bioadhesives derived from natural sources such as proteins and polysaccharides. These biomimetic adhesives offer enhanced biocompatibility and reduced risk of adverse reactions, addressing concerns associated with traditional synthetic adhesives. Bioadhesives exhibit strong adhesive properties, enabling effective wound closure without the need for sutures or staples, thus facilitating quicker recovery and minimizing scarring for patients.
Nanotechnology has played a pivotal role in the enhancement of adhesive materials for surgical applications. Nano-engineered adhesives offer superior strength, flexibility, and tissue adherence, enabling precise wound closure even in challenging surgical scenarios. By leveraging nanomaterials, such as nanoparticles and nanofibers, adhesive formulations can achieve optimal tissue penetration and adhesion, ensuring secure wound closure while promoting natural healing processes. Nanotechnology facilitates the controlled release of therapeutic agents, enabling localized drug delivery to enhance wound healing and prevent infections, further augmenting the clinical utility of surgical adhesives.
Advancements in adhesive chemistry have led to the development of next-generation formulations with enhanced properties, including rapid curing, tunable mechanical strength, and biodegradability. These novel adhesive materials offer surgeons greater versatility and precision in wound closure, enabling minimally invasive procedures and reducing operative times. The integration of smart polymers and additives enables real-time monitoring of adhesive performance and tissue response, ensuring optimal healing outcomes. As the demand for minimally invasive surgical techniques continues to grow, ongoing research and innovation in adhesive materials are poised to drive further advancements in the global surgical glue market, improving patient care and surgical outcomes worldwide.
Restraints:
- Prevalence of Chronic Diseases
- Cost-effectiveness and Efficiency
- Reduced Surgery Time and Hospital Stay
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Decreased Risk of Infections and Complications: The global surgical glue market has seen significant growth, largely due to its capacity to decrease the risk of infections and complications associated with traditional wound closure methods such as sutures and staples. Surgical glues offer a less invasive alternative that minimizes tissue trauma and reduces the exposure of wounds to external contaminants. This is particularly crucial in surgical procedures where infection control is paramount. By forming a protective barrier over the wound, surgical glues effectively seal the incision site, preventing bacteria from entering and proliferating. This results in a lower incidence of post-operative infections, which is a major concern in hospital settings.
In addition to reducing infections, surgical glues also contribute to fewer complications during the healing process. The use of these adhesives can enhance wound healing by providing optimal moisture balance and reducing the need for frequent dressing changes. Unlike sutures, which may cause localized tissue damage and inflammation, surgical glues adhere gently to the skin, promoting a more natural healing environment. This leads to reduced scarring and faster recovery times for patients. The flexibility of surgical glues allows them to move with the body, maintaining the integrity of the wound closure even in areas subject to significant movement or tension.
The decreased risk of infections and complications associated with surgical glues has far-reaching implications for both patient outcomes and healthcare costs. By minimizing the need for additional treatments and hospital readmissions due to infections or wound dehiscence, surgical glues can significantly lower the overall burden on healthcare systems. This is especially important in low-resource settings where healthcare infrastructure may be limited. The efficiency and effectiveness of surgical glues in promoting safer and faster recovery make them an increasingly attractive option in surgical practice worldwide, driving the growth of the global surgical glue market.
Opportunities:
- Collaborations and Partnerships
- Strategic Alliances Between Key Players
- Enhanced Post-surgical Aesthetic Results
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Research and Development Collaborations: Research and Development (R&D) collaborations play a pivotal role in advancing the field of surgical glue, a critical component in modern medical procedures. These collaborations often involve partnerships between pharmaceutical companies, medical device manufacturers, academic institutions, and research organizations. By pooling resources and expertise, these entities can accelerate innovation, improve the efficacy and safety of surgical glues, and bring novel products to market more efficiently.
One significant aspect of R&D collaborations in the global surgical glue market is the focus on biocompatible and bioresorbable materials. Researchers are continually exploring new biomaterials that can mimic the properties of human tissues while promoting wound healing and minimizing adverse reactions. Collaborations between material scientists, biologists, and medical professionals are essential in this endeavor, as they work together to develop formulations that meet the stringent requirements of surgical applications.
R&D collaborations also facilitate the integration of advanced technologies into surgical glue development. This includes the utilization of nanotechnology for precise delivery and targeting, as well as the incorporation of smart materials that can respond to physiological cues within the body. Collaborations with experts in nanomedicine, biomedical engineering, and drug delivery systems are driving innovation in this space, potentially revolutionizing surgical procedures by enabling more precise, minimally invasive techniques. R&D collaborations are instrumental in shaping the future of the global surgical glue market, driving advancements that enhance patient outcomes and transform surgical practices worldwide.
Competitive Landscape Analysis
Key players in Global Surgical Glue Market include:
- Baxter
- B. Braun Melsungen AG
- Cardinal Health
- CR. Bard
- Johnson and Johnson
- OptMed, Inc
- Applied Medical Resources Corporation
- CryoLife
- Integra LifeSciences
- Medtronic
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product
- Market Snapshot, By Indication
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Surgical Glue Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
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Growth in Elective Surgeries
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Rising Number of Surgical Procedures
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Increasing Incidence of Trauma and Accidents
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Innovations and Improvements in Adhesive Materials
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- Restraints
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Prevalence of Chronic Diseases
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Cost-effectiveness and Efficiency
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Reduced Surgery Time and Hospital Stay
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Decreased Risk of Infections and Complications
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- Opportunities
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Collaborations and Partnerships
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Strategic Alliances Between Key Players
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Enhanced Post-surgical Aesthetic Results
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Research and Development Collaborations
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- CompetitiveRivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Surgical Glue Market, By Product, 2021 - 2031 (USD Million)
- Natural Adhesives & Sealants
- Collagen-based Adhesives & Gelatin-based Adhesives
- Synthetic & Semi-Synthetic Adhesives & Sealants
- Hydrogels
- Polyurethane-based Adhesives
- Surgical Glue Market, By Indication, 2021 - 2031 (USD Million)
- Hemostasis
- Tissue Sealing
- Surgical Glue Market, By Application, 2021 - 2031 (USD Million)
- Cardiovascular Surgery
- Plastic Surgery
- Liver & Spleen Laceration
- Orthopedic Surgery
- Burn Bleeding
- Wound Management
- General Surgery
- Others
- Surgical Glue Market, By End User, 2021 - 2031 (USD Million)
- Hospitals
- Ambulatory Surgical Centers
- Specialty Clinics
- Surgical Glue Market, By Geography, 2021 - 2031 (USD Million)
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North America
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United States
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Canada
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Europe
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Germany
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United Kingdom
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France
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Italy
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Spain
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Nordic
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Benelux
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Rest of Europe
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Asia Pacific
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Japan
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China
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India
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Australia & New Zealand
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South Korea
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ASEAN (Association of South East Asian Countries)
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Rest of Asia Pacific
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Middle East & Africa
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GCC
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Israel
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South Africa
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Rest of Middle East & Africa
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Latin America
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Brazil
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Mexico
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Argentina
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Rest of Latin America
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- Surgical Glue Market, By Product, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Baxter
- B. Braun Melsungen AG
- Cardinal Health
- CR. Bard
- Johnson and Johnson
- OptMed, Inc
- Applied Medical Resources Corporation
- CryoLife
- Integra LifeSciences
- Medtronic
- Company Profiles
- Analyst Views
- Future Outlook of the Market