Sulfonylureas Market
By Dosage Form;
Tablets, Capsules, and OthersBy Drugs;
Glyburide, Glipizide, Glimepiride, and OthersBy Indication;
Diabetes and OthersBy End-Users;
Hospitals, Specialty Clinics, Homecare, and OthersBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Introduction
Global Sulfonylureas Market (USD Million), 2021 - 2031
In the year 2024, the Global Sulfonylureas Market was valued at USD 7,072.18 million. The size of this market is expected to increase to USD 8,753.79 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 3.1%.
Sulfonylureas Market
*Market size in USD million
CAGR 3.1 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 3.1 % |
Market Size (2024) | USD 7,072.18 Million |
Market Size (2031) | USD 8,753.79 Million |
Market Concentration | High |
Report Pages | 339 |
Major Players
- Kern
- Mylan
- Abbott
- Takeda
- Normon
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Sulfonylureas Market
Fragmented - Highly competitive market without dominant players
The onset of the COVID-19 pandemic significantly impacted the Sulfonylureas market, primarily due to the heightened awareness of diabetes prevalence among hospitalized COVID-19 patients. The recognition that optimal glycemic control could potentially improve patient outcomes and reduce hospital stays underscored the importance of the oral anti-diabetic drugs market. Individuals with diabetes, known to have compromised immune systems, faced exacerbated conditions with COVID-19 complications, escalating the demand for effective management strategies. Moreover, diabetes and uncontrolled hyperglycemia emerged as significant risk factors for adverse outcomes in COVID-19 patients, further fueling the growth of the sulfonylureas market worldwide.
Sulfonylureas, oral anti-diabetic drugs utilized in treating type 2 diabetes, play a crucial role in regulating chronically high blood sugar levels by enhancing insulin release in the body. The World Health Assembly's May 2021 Resolution on strengthening diabetes prevention and control emphasized enhancing access to medicines for diabetes treatment, highlighting the pivotal role of sulfonylureas and similar drugs in combating this global health challenge. Additionally, initiatives like exploring web-based tools to enhance market transparency for diabetes medicines signify a concerted effort to address the growing burden of diabetes worldwide.
According to the International Diabetes Federation (IDF), the global adult diabetes population reached approximately 537 million in 2021, with projections indicating a surge to 643 million by 2030. This rise is largely attributed to factors such as increasing rates of obesity, unhealthy dietary habits, and sedentary lifestyles, leading to a higher incidence of both Type 1 and Type 2 diabetes cases. The escalating prevalence of diabetes, coupled with rising healthcare expenditures globally, signals a growing demand for anti-diabetic drugs, including sulfonylureas. Moreover, ongoing technological advancements and innovations in drug formulations continue to enhance treatment options, further driving the evolution of the anti-diabetic pharmaceutical market.
Global Sulfonylureas Market Recent Developments
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January 2023: The National Pharmaceutical Pricing Authority (NPPA), India, fixed the retail price of 12 scheduled formulations under the Drugs (Prices Control) Order, 2013 (NLEM 2022). The retail price of one tablet of anti-diabetes combination drug Glimepiride, Voglibose, and Metformin (extended-release) was fixed at INR 13.83 (USD 0.17).
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March 2022: Because of the similarities in chemical structure and mode of action, the Food and Drug Administration considered the possible increased risk of cardiovascular mortality from tolbutamide applied to all other sulfonylurea drugs. Therefore, the labeling for oral hypoglycemic drugs of the sulfonylurea class shall include a warning concerning the possible increased risk of cardiovascular mortality associated with such use as 'Special Warning on Increased Risk of Cardiovascular Mortality.
Sulfonylureas Market Segment Analysis
In this report, the Sulfonylureas Market has been segmented by Dosage Form, Drug, Indication, End-Users and Geography.
Sulfonylureas Market, Segmentation by Dosage Form
The Sulfonylureas Market has been segmented by Dosage Form into and Tablets, Capsules and Others
Tablets
Tablets hold a dominant market share of around 55% due to their ease of administration, cost-effectiveness, and widespread accessibility. Their flexibility in dosage adjustments makes them a preferred choice among healthcare providers for managing long-term glycemic control in diabetic patients.
Capsules
Capsules account for nearly 30% of the market, offering benefits such as better swallowing comfort and reduced gastric irritation. They are often chosen for patients requiring enhanced drug stability and targeted release, supporting improved compliance and therapeutic outcomes.
Others
Other dosage forms collectively contribute to approximately 15% of sales, including liquid formulations and innovative delivery methods. These options cater to special patient groups such as pediatrics or those with swallowing difficulties, expanding treatment accessibility.
Sulfonylureas Market, Segmentation by Drug
The Sulfonylureas Market has been segmented by Drug into and Glyburide, Glipizide, Glimepiride, and Others.
Glyburide
Glyburide commands about 35% of the market due to its high efficacy in lowering blood glucose and affordability. It is widely prescribed for type 2 diabetes patients, though its risk of hypoglycemia necessitates careful dose management.
Glipizide
Glipizide holds nearly 30% share, favored for its rapid onset of action and shorter half-life, which help reduce hypoglycemia risk. It is especially recommended for patients with renal impairment where other sulfonylureas may not be suitable.
Glimepiride
Glimepiride accounts for around 25% of the market, appreciated for its once-daily dosing and lower incidence of side effects. Its balanced glucose control and improved patient compliance make it a preferred choice among healthcare providers.
Others
Other drugs in this category contribute roughly 10% of sales, including less commonly prescribed sulfonylureas and newer formulations. These serve niche patient needs and offer alternatives for those intolerant to first-line options.
Sulfonylureas Market, Segmentation by Indication
In this report, the Sulfonylureas Market has been segmented by Indication into Diabetes ,Others
Diabetes
The diabetes segment dominates the market with over 90% share, driven by the growing prevalence of type 2 diabetes and the cost-effectiveness of sulfonylureas in blood glucose control. Their established clinical efficacy ensures consistent adoption in treatment regimens worldwide.
Others
The others segment holds less than 10% share, comprising off-label uses and research applications. While limited in scope, it includes emerging therapeutic investigations that could expand the clinical utility of sulfonylureas in the future.
Sulfonylureas Market, Segmentation by End-Users
In this report, the Sulfonylureas Market has been segmented by End-Users into Hospitals, Specialty Clinics, Homecare, and Others
Hospitals
Hospitals account for nearly 45% of the market, driven by the high volume of in-patient and out-patient treatments for diabetes. Their integrated diagnostic and therapeutic services enable comprehensive disease management and timely medication administration.
Specialty Clinics
Specialty clinics hold about 30% share, focusing on endocrinology and diabetes care. These facilities offer personalized treatment plans and advanced monitoring, improving patient adherence and long-term glycemic control outcomes.
Homecare
Homecare services represent around 15% of demand, supported by the rise of self-monitoring technologies and telemedicine consultations. This segment is growing as patients seek convenient and cost-effective disease management options outside traditional healthcare settings.
Others
The others segment, contributing approximately 10%, includes community health programs and non-profit healthcare initiatives. These settings expand access to sulfonylurea treatments, particularly in underserved or rural populations.
Sulfonylureas Market, Segmentation by Geography
In this report, the Sulfonylureas Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
Sulfonylureas Market Share (%), by Geographical Region
North America, Europe, Asia Pacific, Middle East and Africa, and Latin America. Each region presents unique market dynamics influenced by factors such as disease prevalence, healthcare infrastructure, regulatory frameworks, and socio-economic conditions.
North America
North America captures around 35% of the market, supported by a high diabetes prevalence, advanced healthcare infrastructure, and widespread access to medications. Strong insurance coverage and ongoing clinical research further boost sulfonylurea adoption in this region.
Europe
Europe holds nearly 25% share, driven by comprehensive healthcare systems and growing awareness of cost-effective therapies. Government-supported diabetes management programs enhance patient accessibility and encourage the use of established oral antidiabetic drugs.
Asia Pacific
Asia Pacific accounts for about 30% of demand, fueled by the rapidly rising diabetic population and affordable treatment options. Expanding healthcare infrastructure and increased screening initiatives support strong market growth in countries such as China and India.
Middle East and Africa
This region contributes roughly 5%, with growth driven by increasing lifestyle-related diabetes cases and improved healthcare access. Government health campaigns and international aid initiatives are helping expand treatment reach.
Latin America
Latin America holds around 5% share, supported by rising healthcare expenditure and growing awareness of diabetes management. Urbanization and better availability of medications contribute to steady market expansion in this region.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Sulfonylureas Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers :
- Rising Diabetes Prevalence
- Cost-effectiveness
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Cost-effectiveness - The Global Sulfonylureas Market is experiencing robust growth, driven by its cost-effectiveness and efficacy in managing type 2 diabetes mellitus. Sulfonylureas have long been recognized for their affordability compared to newer diabetes medications, making them a preferred choice in regions where healthcare budgets are constrained. Despite the availability of alternative therapies, sulfonylureas remain widely prescribed due to their proven track record in lowering blood sugar levels and improving glycemic control in diabetic patients. This cost-effectiveness is particularly significant in developing countries where access to expensive diabetes treatments may be limited, driving the sustained demand for sulfonylureas.
The continued growth of the Global Sulfonylureas Market is also attributed to the expanding diabetic population worldwide. With diabetes prevalence on the rise, particularly in emerging economies, there is an increasing need for affordable and accessible treatment options. Sulfonylureas offer a cost-effective solution for managing diabetes, especially in resource-limited settings, where healthcare infrastructure may be less developed. As healthcare systems strive to optimize treatment outcomes while managing costs, sulfonylureas play a crucial role in providing affordable and efficacious therapy for diabetic patients, contributing to the overall growth and sustainability of the Global Sulfonylureas Market.
Restraints :
- Safety Concerns
- Limited Efficacy
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Side Effects - The Global Sulfonylureas Market has witnessed significant growth driven by the rising prevalence of diabetes worldwide and the increasing demand for effective oral anti-diabetic medications. Sulfonylureas, commonly used in the treatment of type 2 diabetes, have contributed to this growth by helping patients achieve better glycemic control and manage their blood sugar levels effectively. With the continuous introduction of innovative formulations and therapeutic advancements, the market for sulfonylureas is expected to expand further in the coming years as healthcare providers and patients continue to prioritize optimal diabetes management.
It's important to note that the use of sulfonylureas is associated with certain side effects, including hypoglycemia (low blood sugar levels) and weight gain. While these side effects are generally manageable and well-tolerated by most patients, healthcare professionals need to monitor patients closely, especially those at higher risk, to mitigate potential adverse effects. Despite these considerations, the overall benefits of sulfonylureas in controlling diabetes and reducing the risk of complications outweigh the associated side effects, making them an essential component of diabetes management regimens globally.
Opportunities :
- Developing Markets
- Combination Therapies
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Research & Development - The global Sulfonylureas market is witnessing significant growth propelled by ongoing research and development activities aimed at advancing treatment options for diabetes. With the increasing prevalence of diabetes worldwide, there is a growing demand for effective medications to manage the condition, driving investment in R&D initiatives focused on sulfonylureas and related therapies. Pharmaceutical companies are actively engaged in developing novel formulations, improving drug delivery systems, and exploring combination therapies to enhance the efficacy and safety profiles of sulfonylurea medications.
Advancements in technology and innovative drug discovery approaches are facilitating the development of next-generation sulfonylureas with improved pharmacokinetic properties and reduced side effects. These efforts are aimed at addressing the evolving needs of diabetic patients, including those with comorbidities or specific treatment preferences. Furthermore, collaborations between academia, research institutions, and pharmaceutical companies are fostering a collaborative environment conducive to breakthroughs in diabetes management, driving the growth and innovation in the global Sulfonylureas market.
Competitive Landscape Analysis
Key players in Global Sulfonylureas Market includ
- Kern
- Mylan
- Abbott
- Takeda
- Normon
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Dosage Form
- Market Snapshot, By Drugs
- Market Snapshot, By Indication
- Market Snapshot, By End-Users
- Market Snapshot, By Region
- Sulfonylureas Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Rising Diabetes Prevalence
- Cost-effectiveness
- Cost-effectiveness
- Restraints
- Safety Concerns
- Limited Efficacy
- Side Effects
- Opportunities
- Developing Markets
- Combination Therapies
- Research & Development
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
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Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
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Sulfonylureas Market, By Dosage Form, 2021- 2031 (USD Million)
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Tablets
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Capsules
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Others
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- Sulfonylureas Market, By Drugs, 2021- 2031 (USD Million)
- Glyburide
- Glipizide
- Glimepiride
- Others
- Sulfonylureas Market, By Indication , 2021- 2031 (USD Million)
- Diabetes
- Others
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Sulfonylureas Market, By End-Users , 2021- 2031 (USD Million)
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Hospitals
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Specialty Clinics
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Homecare
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Others
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- Sulfonylureas Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
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- Competitive Landscape
- Company Profiles
- Kern
- Mylan
- Abbott
- Takeda
- Normon
- Company Profiles
- Analyst Views
- Future Outlook of the Market