Strand Displacement Amplification (SDA) Market

By Sample Type;

Blood Samples and Tissue Samples

By Application;

Tuberculosis, Hepatitis, Pneumonia, Malaria, and Cancer

By Technology;

Real-Time PCR and Polymerase Chain Reaction (PCR))

By End User;

Research Institutes, Hospitals, and Diagnostic Laboratories

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn485152212 Published Date: August, 2025

Strand Displacement Amplification (Sda) Market Overview

Strand Displacement Amplification (Sda) Market (USD Million)

Strand Displacement Amplification (Sda) Market was valued at USD 1,615.42 million in the year 2024. The size of this market is expected to increase to USD 2,187.93 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 4.4%.


Strand Displacement Amplification (SDA) Market

*Market size in USD million

CAGR 4.4 %


Study Period2025 - 2031
Base Year2024
CAGR (%)4.4 %
Market Size (2024)USD 1,615.42 Million
Market Size (2031)USD 2,187.93 Million
Market ConcentrationHigh
Report Pages300
1,615.42
2024
2,187.93
2031

Major Players

  • BioHelix Corporation
  • Quidel Corporation
  • NuProbe Global
  • Meridian Bioscience, Inc.
  • AmpliPhi Biosciences Corporation
  • Lucigen Corporation
  • Meso Scale Diagnostics, LLC
  • New England Biolabs, Inc.
  • OptiGene Limited
  • BioFire Diagnostics, LLC

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Strand Displacement Amplification (SDA) Market

Fragmented - Highly competitive market without dominant players


The Strand Displacement Amplification (SDA) Market is expanding as clinical diagnostics and food safety labs increasingly adopt rapid isothermal DNA amplification systems for accurate detection of pathogens and genetic markers. Nearly 65% of molecular testing facilities now prefer SDA-based platforms for quick, precise results. This shift is catalyzing innovation and market expansion, driven by synergy between biotech engineers and clinical researchers.

Platform Enhancements Strengthening Field Application
Around 62% of technology vendors are enhancing systems with features like multiplex detection panels, integrated fluorescence monitoring, magnetic bead purification, and portable assay formats. These technological advancements elevate sensitivity, throughput, and field usability. Collaborations between molecular biologists and instrument developers are speeding widespread adoption.

Collaborative Validation Boosting Application Scope
Cross-disciplinary validation efforts spanning public health agencies, veterinary laboratories, and biotech firms have resulted in a 59% rise in SDA assay usage for foodborne and infectious disease screening. These cross-functional collaborations support rigorous performance validation, standardized workflows, and operator training—yielding growth through quality assurance integration.

Connected Diagnostics and AI Integration on the Horizon
With projections showing that over 70% of future SDA solutions will include mobile connectivity, cloud‑based result sharing, and AI‑assisted interpretation modules, the market is set to enter a phase of real-time decentralized diagnostics. This leap will empower remote testing sites, improve outbreak responsiveness, and embed SDA into global surveillance networks with unprecedented accessibility.

In this report, the Strand Displacement Amplification (Sda) Market has been segmented by Sample Type, Application, Technology, End User, and Geography.

Strand Displacement Amplification (Sda) Market, Segmentation by Sample Type

The Strand Displacement Amplification (Sda) Market has been segmented by Blood Samples and Tissue Samples.

Blood Samples

Blood‑based SDA methods hold the lion’s share of the market (about 60 %), thanks to their minimal invasiveness and ease of repeat testing. Widely used in clinical diagnostics and point‑of‑care setups, blood draws follow standard workflows that streamline sample processing. Recent technological enhancements—such as optimized primers and higher‑efficiency enzymes—have pushed assay sensitivity past 95 %, improving diagnostic accuracy. As SDA applications expand into infectious disease screening and tumor marker monitoring, this sub‑segment is expected to grow at an approximate annual rate of 8 %.

Tissue Samples

Tissue‑based SDA commands roughly 40 % of the overall market, delivering high specificity and localization, especially valuable in cancer diagnostics and histopathology. Growth in this sub‑segment has been tempered by the invasive nature of biopsies and the complexity of sample preparation. Nevertheless, many clinical tissue assays achieve sensitivities near 90 % and specificities exceeding 98 %. As personalized medicine and molecular pathology approaches gain momentum, tissue‑based SDA is projected to advance at a CAGR of around 6 %.

Strand Displacement Amplification (Sda) Market, Segmentation by Application

The Strand Displacement Amplification (Sda) Market has been segmented by Hepatitis, Pneumonia, Malaria, and Cancer.

Hepatitis

SDA technology for hepatitis detection captures around 28% of the market, fueled by increasing prevalence of hepatitis B and C worldwide. These assays deliver rapid results with over 95% sensitivity, making them a preferred choice for early and reliable viral detection. Expanding government-led screening programs and improved test accessibility are accelerating growth, particularly in high‑risk demographics.

Pneumonia

Pneumonia diagnostics using SDA account for close to 25% of the market, offering 93%+ accuracy in detecting a range of bacterial and viral agents. The speed and precision of these tests help clinicians initiate targeted treatments quickly, reducing unnecessary antibiotic use. Rising incidences of hospital-acquired pneumonia are further enhancing the segment’s adoption rate.

Malaria

With a market share of about 22%, SDA‑based malaria diagnostics are critical for detecting low‑level parasitemia cases. They consistently achieve 90%+ sensitivity and 95%+ specificity, even in under-resourced areas. Global initiatives targeting malaria elimination in Africa and Asia are expected to significantly drive uptake over the next decade.

Cancer

Cancer-focused SDA applications hold nearly 25% of the global market, playing a vital role in identifying tumor biomarkers and genetic mutations. Delivering 97%+ sensitivity and 98%+ specificity, these tests support early cancer detection and enable precision treatment strategies. The rising global cancer burden and advancements in molecular oncology continue to push this segment forward.

Strand Displacement Amplification (Sda) Market, Segmentation by Technology

The Strand Displacement Amplification (Sda) Market has been segmented by Real-Time PCR and Polymerase Chain Reaction (PCR)).

Real-Time PCR

Real-Time PCR‑driven SDA solutions represent about 55% of the global market, valued for their ability to deliver both qualitative and quantitative results with over 96% accuracy. These platforms are integral to applications such as infectious disease screening, oncology diagnostics, and genetic analysis. The demand for rapid, high‑throughput, and automated testing is accelerating adoption, particularly in hospitals and advanced research labs.

Polymerase Chain Reaction (PCR)

Traditional PCR‑based SDA methods capture nearly 45% of market share, offering dependable performance with 92%+ sensitivity across diverse applications. Their cost-effectiveness makes them especially popular in resource-limited laboratories while still supporting high standards in clinical diagnostics and pathogen detection. Growing utilization in academic and industrial research continues to drive consistent segment growth.

Strand Displacement Amplification (Sda) Market, Segmentation by End User

The Strand Displacement Amplification (Sda) Market has been segmented by End User into Research institutes, Hospitals and Diagnostic laboratories.

Research Institutes

Research institutes make up about 35% of the Strand Displacement Amplification market, driven by increased funding in molecular biology and genomics. These organizations utilize SDA for innovative diagnostic development, pathogen detection, and genetic analysis. Support from government grants and private investments is accelerating the creation of more sensitive and faster assays.

Hospitals

Hospitals command nearly 40% of the SDA market, applying the technology for rapid diagnostics and patient monitoring. Known for achieving over 95% accuracy, SDA is crucial in emergency care and surgical diagnostics. The surge in point‑of‑care testing demand and the need for quick turnaround times are significantly boosting adoption rates.

Diagnostic Laboratories

Diagnostic laboratories account for close to 25% of the market, specializing in high‑volume testing for infectious diseases, cancer biomarkers, and genetic disorders. With consistent 93%+ sensitivity, SDA supports mass screening and confirmation testing. Automation advancements and streamlined workflows are improving both throughput and cost-effectiveness in these facilities.

Strand Displacement Amplification (Sda) Market, Segmentation by Geography

In this report, the Strand Displacement Amplification (Sda) Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.

Regions and Countries Analyzed in this Report

Legend
North America
Rest of North America
Europe
Rest of Europe
Asia Pacific
Rest of Asia Pacific
Middle East and Africa
Rest of Middle East and Africa
Latin America
Rest of Latin America
Rest of the World

Strand Displacement Amplification (Sda) Market Share (%), by Geographical Region

North America

North America leads the Strand Displacement Amplification market with about 38% share, benefiting from advanced healthcare infrastructure and high molecular diagnostics adoption. Significant research funding and the presence of major industry players strengthen its dominance. The U.S. remains the primary growth driver within the region.

Europe

Europe captures close to 28% of the market, driven by demand in clinical diagnostics, infectious disease detection, and genetic research. Supportive regulatory frameworks and innovations in laboratory automation are fueling steady expansion. Germany, the UK, and France are the leading contributors.

Asia Pacific

Asia Pacific holds around 22% of the market, supported by expanding healthcare access and rising investments in diagnostics. Strong growth in China and India, coupled with government-led disease control initiatives, positions the region for the fastest CAGR during the forecast period.

Middle East and Africa

The Middle East and Africa account for approximately 7% of the SDA market, with momentum building in urban healthcare hubs. Investment in diagnostic infrastructure and efforts to expand testing capabilities are driving growth, though rural accessibility remains limited.

Latin America

Latin America represents about 5% of the global market, with expansion fueled by diagnostic network growth and public health initiatives. Brazil and Mexico dominate regional adoption, supported by rising healthcare spending and awareness of molecular testing benefits.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Sample Type
    2. Market Snapshot, By Application
    3. Market Snapshot, By Technology
    4. Market Snapshot, By End User
    5. Market Snapshot, By Region
  4. Strand Displacement Amplification (Sda) Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. High Sensitivity

        2. Isothermal Amplification

        3. Molecular Diagnostics

        4. Infectious Disease Detection

      2. Restraints
        1. Sample Complexity

        2. Sensitivity and Specificity Concerns

        3. Limited Commercialization

        4. Acceptance in Clinical Settings

      3. Opportunities
        1. Point-of-care testing

        2. Infectious disease diagnostics

        3. Genetic testing

        4. Oncology diagnostics

    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Strand Displacement Amplification (Sda) Market, By Sample Type, 2021 - 2031 (USD Million)

      1. Blood Samples

      2. Tissue Samples

    2. Strand Displacement Amplification (Sda) Market, By Technology, 2021 - 2031 (USD Million)

      1. Real-Time PCR

      2. Polymerase Chain Reaction (PCR))

    3. Strand Displacement Amplification (Sda) Market, By Application, 2021 - 2031 (USD Million)
      1. Tuberculosis
      2. Hepatitis
      3. Pneumonia
      4. Malaria
      5. Cancer
    4. Strand Displacement Amplification (Sda) Market, By End User, 2021 - 2031 (USD Million)
      1. Research Institutes
      2. Hospitals
      3. Diagnostic Laboratories
    5. Strand Displacement Amplification (Sda) Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. BioHelix Corporation
      2. Quidel Corporation
      3. NuProbe Global
      4. Meridian Bioscience, Inc.
      5. AmpliPhi Biosciences Corporation
      6. Lucigen Corporation
      7. Meso Scale Diagnostics, LLC
      8. New England Biolabs, Inc.
      9. OptiGene Limited
      10. BioFire Diagnostics, LLC
  7. Analyst Views
  8. Future Outlook of the Market