Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market

By Therapeutic Area;

Type 2 Diabetes Mellitus and Cardiovascular Diseases

By Drug Type;

Empagliflozin and Dapagliflozin

By Application ;

Hospital Pharmacy and Retail Pharmacy

By Route of Administration;

Oral and Parenteral

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031).
Report ID: Rn138133569 Published Date: August, 2025 Updated Date: September, 2025

Sodium-Dependent Glocose Co-Transporter 2 (SGLT 2) Market Overview

Sodium-Dependent Glocose Co-Transporter 2 (SGLT 2) Market (USD Million)

Sodium-Dependent Glocose Co-Transporter 2 (SGLT 2) Market was valued at USD 10,412.16 million in the year 2024. The size of this market is expected to increase to USD 21,024.56 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 10.6%.


Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market

*Market size in USD million

CAGR 10.6 %


Study Period2025 - 2031
Base Year2024
CAGR (%)10.6 %
Market Size (2024)USD 10,412.16 Million
Market Size (2031)USD 21,024.56 Million
Market ConcentrationLow
Report Pages301
10,412.16
2024
21,024.56
2031

Major Players

  • Janssen Pharmaceuticals
  • Eli Lilly
  • Bristol Myers Squibb
  • AstraZeneca Pharmaceuticals

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market

Fragmented - Highly competitive market without dominant players


The Sodium-Dependent Glocose Co-Transporter 2 (SGLT 2) Market is experiencing strong growth as these therapies transform the management of type 2 diabetes and related complications. Currently, more than 60% of patients prefer SGLT2 drugs for their combined impact on glucose regulation and cardiovascular health. Increased awareness and wider treatment adoption are driving the rapid expansion of this market.

Rising Demand in Diabetes Care
With over 45% of diabetes patients being targeted for SGLT2 therapy, demand is rising sharply. These treatments reduce hospitalization risk and provide renal protection, making them more effective compared to conventional alternatives. The growing adoption highlights the ongoing shift toward advanced therapies in chronic disease care.

Integration with Cardiovascular Benefits
Nearly 50% of prescriptions are linked to cardiovascular benefits, as SGLT2 inhibitors have proven to lower the risks of heart failure progression. Their inclusion in comprehensive treatment plans positions them as critical drugs for managing both metabolic and cardiovascular conditions. This cross-functional value has reinforced their role in modern healthcare practices.

Innovation and Expansion of Indications
Continuous research and clinical trials are enhancing market growth, with more than 40% of ongoing studies focusing on new indications such as chronic kidney disease and non-diabetic heart failure. These advancements not only diversify their applications but also secure the relevance of SGLT2 inhibitors as multipurpose therapies in the evolving healthcare landscape.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Therapeutic Area
    2. Market Snapshot, By Drug Type
    3. Market Snapshot, By Application
    4. Market Snapshot, By Route of Administration
    5. Market Snapshot, By Region
  4. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market Dynamics

    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Increasing prevalence of diabetes
        2. Rising awareness of SGLT2 inhibitors
        3. Growing geriatric population
      2. Restraints
        1. Potential side effects of SGLT2 inhibitors
        2. High cost of SGLT2 inhibitors
      3. Opportunities
        1. Development of new SGLT2 inhibitors
        2. Expansion into new markets
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry

  5. Market Segmentation
    1. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market, By Therapeutic Area, 2021- 2031 (USD Million)

      1. Type 2 Diabetes Mellitus

      2. Cardiovascular Diseases

    2. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market, By Drug Type, 2021- 2031 (USD Million)
      1. Empagliflozin
      2. Dapagliflozin
    3. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market, By Application , 2021- 2031 (USD Million)
      1. Hospital Pharmacy
      2. Retail Pharmacy
    4. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market, By Route of Administration, 2021- 2031 (USD Million)

      1. Oral

      2. Parenteral

    5. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Janssen Pharmaceuticals
      2. Eli Lilly
      3. Bristol Myers Squibb
      4. AstraZeneca Pharmaceuticals
  7. Analyst Views
  8. Future Outlook of the Market