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Add to CartGlobal Rat Model Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Type;
Outbred, and KnockoutBy Service;
Cryopreservation, Breeding, Re-Derivation, Genetic Testing, Quarantine Depending, and OthersBy Technology;
Embryonic Stem Cell, and MicroinjectionBy Application;
Oncology, Neurology, Immunology, Toxicology, and OthersBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Rat Model Market Overview
Rat Model Market (USD Million)
Rat Model Market was valued at USD 7,227.42 million in the year 2024. The size of this market is expected to increase to USD 12,226.84 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 7.8%.
Global Rat Model Market Growth, Share, Size, Trends and Forecast
*Market size in USD million
CAGR 7.8 %
| Study Period | 2025 - 2031 |
|---|---|
| Base Year | 2024 |
| CAGR (%) | 7.8 % |
| Market Size (2024) | USD 7,227.42 Million |
| Market Size (2031) | USD 12,226.84 Million |
| Market Concentration | Medium |
| Report Pages | 319 |
Major Players
- Charles River Laboratories
- Envigo
- genOway
- Laboratory Corporation of America Holdings (LabCorp)
- Janvier Labs
- Taconic Biosciences, Inc.
- TransViragen, Inc.
- Biomere
- Cyagen Biosciences
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Global Rat Model Market
Fragmented - Highly competitive market without dominant players
The Rat Model Market is gaining significant momentum as researchers increasingly adopt rodent models to explore human diseases and test therapeutic efficacy. The use of genetically engineered rats has surged, driven by the need for precise modeling in areas such as oncology, immunology, and toxicology. This market has witnessed a growth of over 35% in demand for transgenic rat models, reflecting a broader push toward preclinical innovation.
Driving Forces
Key factors contributing to this expansion include advancements in gene-editing tools like CRISPR and increasing funding for life sciences research. The demand for more reliable, cost-effective, and scalable animal models has pushed the adoption of rats due to their higher biological similarity to humans compared to mice. Preclinical trials using rat models have increased by nearly 28%, indicating rising confidence in their translational relevance.
Technological Integration
The market is being revolutionized by the integration of technologies such as AI-driven behavioral analysis, real-time monitoring, and high-throughput screening platforms. These innovations have enhanced data accuracy and reduced experimental variability, contributing to a 40% improvement in study reproducibility. As precision medicine evolves, rat models are increasingly preferred for neurodegenerative and metabolic disease studies
Ethical and Regulatory Influence
The market is also shaped by stringent regulatory guidelines and ethical frameworks surrounding animal use in research. Regulatory compliance solutions and welfare monitoring systems have grown by over 30%, emphasizing the industry's shift toward humane and standardized practices. These trends are fostering trust and encouraging investments across pharmaceutical and academic institutions.
Future Outlook
The Rat Model Market is expected to experience accelerated evolution with rising research in personalized medicine and chronic disease modeling. Innovation in model development and validation has shown a 25% rise in collaborative R&D initiatives, highlighting sustained momentum. The market's future lies in developing next-gen models that mimic complex human pathologies with higher precision, supporting its critical role in therapeutic innovation.
Rat Model Market Recent Developments
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August 2016, Charles River Laboratories, Inc. entered into a strategic partnership with The Milner Therapeutics Institute and Consortium (UK). This partnership with the Consortium allows the academic institutions access to Charles River's early discovery and drug development and services for the early stage drug development processes.
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September, 2016, Charles River Laboratories International, Inc. acquired Agilux Laboratories (US), a provider of bioanalytical services, drug metabolism and pharmacokinetic services, and pharmacology services. This acquisition is expected to compliment Charles River's non-clinical portfolio and improve the clients' early-stage research efforts by enabling them to seamlessly transition their drug candidates through the discovery and safety assessment process.
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October 2015, Horizon Discovery Group plc expanded its UK based headquarters. The new facility is likely to accommodate 200 employees across manufacturing, services, research, and general and administrative functions.
Rat Model Market Segment Analysis
In this report, the Rat Model Market has been segmented by Type, Service, Technology, Application, and Geography.
Rat Model Market, Segmentation by Type
The Rat Model Market has been segmented by Type into Outbred, and Knockout.
Outbred
Outbred rat models are widely used in preclinical research due to their genetic diversity and ability to mimic human population variability. This segment holds approximately 65% of the overall market share.
Knockout
Knockout rat models are essential for understanding gene function and disease mechanisms, particularly in target validation and drug discovery. Their precision and specificity have contributed to a market share of about 35%.
Rat Model Market, Segmentation by Service
The Rat Model Market has been segmented by Service into Cryopreservation, Breeding, Re-Derivation, Genetic Testing, Quarantine Depending, and Others.
Cryopreservation
Cryopreservation services help in preserving the genetic material of valuable rat models for future use. This segment holds approximately 20% of the overall market share, supporting long-term research needs.
Breeding
Breeding services ensure the continuous supply of genetically stable and high-quality rat models. With extensive use in various research areas, this segment captures about 30% of the market.
Re-Derivation
Re-derivation services are essential for producing clean and pathogen-free rat colonies, particularly for specialized research. This segment contributes around 15% to the total market share.
Genetic Testing
Genetic testing services play a crucial role in verifying the genotype and phenotype of rat models, ensuring consistency and reliability. This segment holds about 10% of the market.
Quarantine Depending
Quarantine services ensure the safe introduction of new rat models into controlled environments, minimizing pathogen risks. This segment represents approximately 15% of the market.
Others
This category includes additional services such as consulting, training, and logistics support for rat model management. It holds a market share of around 10%.
Rat Model Market, Segmentation by Technology
The Rat Model Market has been segmented by Technology into Embryonic Stem Cell, and Microinjection.
Embryonic Stem Cell
Embryonic stem cell technology is widely used for creating genetically modified rat models with precise gene targeting capabilities. This segment holds approximately 55% of the market share, driven by its accuracy and versatility.
Microinjection
Microinjection technology involves directly injecting genetic material into rat embryos to achieve gene modifications. This method contributes to about 45% of the total market share, valued for its simplicity and speed.
Rat Model Market, Segmentation by Application
The Rat Model Market has been segmented by Appllication into Oncology, Neurology, Immunology, Toxicology, and Others.
Oncology
Rat models are extensively used in oncology research for studying tumor biology and testing anticancer drugs. This application holds approximately 35% of the overall market share, driven by the need for reliable cancer models.
Neurology
Neurology research relies on rat models to understand neurodegenerative diseases and evaluate potential therapeutic interventions. This segment captures about 25% of the market share.
Immunology
In the field of immunology, rat models are critical for studying immune system responses and developing new immunotherapies. This application represents approximately 20% of the market.
Toxicology
Toxicology studies employ rat models to assess the safety and toxicity of new compounds and products. This segment contributes around 15% of the total market share.
Others
This category includes diverse applications such as cardiology, metabolic research, and rare disease studies, holding about 5% of the market share.
Rat Model Market, Segmentation by Geography
In this report, the Global Rat Model Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Regions and Countries Analyzed in this Report
Rat Model Market Share (%),By Geographical Region
North America
North America dominates the rat model market due to its advanced research infrastructure and high demand for preclinical studies. This region accounts for approximately 40% of the overall market share.
Europe
Europe maintains a significant presence in the rat model market, supported by strong regulatory frameworks and a growing focus on drug development. It contributes around 30% of the market.
Asia Pacific
The Asia Pacific region is experiencing rapid growth in the rat model market due to increased research funding and expanding biopharmaceutical sectors. It holds about 20% of the market share.
Middle East and Africa
Middle East and Africa are gradually adopting rat models in research, particularly in university and healthcare settings. This segment represents approximately 5% of the market.
Latin America
Latin America shows steady growth in the rat model market, supported by improving healthcare infrastructure and a rising focus on preclinical studies. This region accounts for about 5% of the total market share.
Rat Model Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Rat Model Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces—Drivers, Restraints, and Opportunities—affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
| Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
|---|---|---|---|---|---|
| Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development |
| Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
| Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers, Restraints and Opportunities Analysis
Drivers:
- Advancements in Genetic Engineering Technologies
- High Relevance to Human Disease Models
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Rising Investments in Biomedical Research - The increase in funding for biomedical research is significantly boosting demand for rat models across research and pharmaceutical settings. Government organizations and private firms are channeling substantial investments into studying disease mechanisms, enhancing drug discovery, and validating new treatment pathways. Rats serve as essential models due to their physiological similarity to humans, especially in fields like cardiovascular disease, oncology, and neuroscience.
Modern research trends emphasize targeted and translational medicine, increasing reliance on rat models for preclinical trials. These models provide key insights into pharmacodynamics, toxicity, and treatment efficacy, making them indispensable across drug development stages. As a result, funding continues to support development of more precise and human-relevant rat strains.
Collaborations between biotech firms and research institutions are accelerating innovation in rat-based studies. This includes exploring gene-environment interactions and personalized disease models. The growing interest in personalized medicine further reinforces the demand for genetically engineered and disease-specific rat models.
This trend of increasing investment is expected to support infrastructure upgrades, wider adoption of transgenic models, and expanded technical training, collectively strengthening the role of rat models in advanced biomedical research.
Restraints:
- Availability of Alternative In Vitro Methods
- Stringent Animal Welfare Regulations
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High Cost of Breeding and Maintenance - One of the primary challenges facing the rat model market is the high cost of breeding and maintenance. Sustaining large colonies of laboratory rats demands dedicated housing facilities, strict sanitation protocols, and specialized staff. These requirements lead to significant operational expenses, which are often burdensome for smaller labs or resource-limited institutions.
The cost intensifies when dealing with genetically modified or disease-specific rats, as maintaining their genetic integrity requires controlled breeding and advanced technologies. These financial demands often limit access, particularly for institutions without large-scale funding.
Rats have lower reproductive efficiency and longer breeding cycles compared to mice, which makes them less suitable for rapid or high-throughput studies. Space, veterinary care, and nutritional requirements further elevate long-term costs, making alternatives like in vitro models more attractive in certain cases.
This financial strain may hinder market expansion unless mitigated by broader subsidies, shared-resource programs, or lower-cost breeding technologies, which are essential to maintain accessibility and scalability of rat model use in critical research areas.
Opportunities:
- Development of Humanized Rat Models
- Growing Demand for Oncology Research
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Collaborations with Academic Research Institutions - Strategic alliances with academic research institutions offer a major opportunity to accelerate the adoption and refinement of rat models. These partnerships foster access to innovative disease applications, validation techniques, and behavioral studies in real-world lab environments, helping providers better align with emerging scientific demands.
By collaborating, academic centers gain access to custom model development and expert technical support, while suppliers benefit from feedback and performance data that inform ongoing improvements. Shared infrastructure and resources reduce costs while enhancing research throughput and quality.
These collaborations also enable training programs and protocol standardization, improving best practices for rat care, ethical compliance, and data reproducibility. Such frameworks support stronger institutional trust and drive sustainable market growth.
As personalized and translational research gains momentum, academia will remain central to innovation in rat-based studies. Strengthening these ties will unlock new therapeutic insights and reinforce rat models as essential tools in future scientific advancement.
Rat Model Market Competitive Landscape Analysis
Key players in Rat Model Market include:
- Charles River Laboratories
- Envigo
- genOway
- Laboratory Corporation of America Holdings (LabCorp)
- Janvier Labs
- Taconic Biosciences, Inc.
- TransViragen, Inc.
- Biomere
- Cyagen Biosciences
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Market Share Analysis
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Service
- Market Snapshot, By Technology
- Market Snapshot, By Application
- Market Snapshot, By Region
- Rat Model Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
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Advancements in Genetic Engineering Technologies
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High Relevance to Human Disease Models
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Rising Investments in Biomedical Research
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- Restraints
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Availability of Alternative In Vitro Methods
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Stringent Animal Welfare Regulations
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High Cost of Breeding and Maintenance
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- Opportunities
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Development of Humanized Rat Models
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Growing Demand for Oncology Research
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Collaborations with Academic Research Institutions
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Rat Model Market, By Type, 2021 - 2031 (USD Million)
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Outbred
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Knockout
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Rat Model Market, By Service, 2021 - 2031 (USD Million)
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Cryopreservation
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Breeding
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Re-Derivation
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Genetic Testing
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Quarantine Depending
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Others
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- Rat Model Market, By Technology, 2021 - 2031 (USD Million)
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Embryonic Stem Cell
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Microinjection
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Rat Model Market, By Application, 2021 - 2031 (USD Million)
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Oncology
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Neurology
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Immunology
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Toxicology
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Others
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- Rat Model Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Rat Model Market, By Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Charles River Laboratories
- Envigo
- genOway
- Laboratory Corporation of America Holdings (LabCorp)
- Janvier Labs
- Taconic Biosciences, Inc.
- TransViragen, Inc.
- Biomere
- Cyagen Biosciences
- Company Profiles
- Analyst Views
- Future Outlook of the Market