Pemetrexed Market
By Type;
Injectable and OralBy Product Type;
Branded and GenericBy Strength;
100 mg and 500 mg.By Application;
Malignant Pleural Mesothelioma and Non-Squamous NSCLCBy Distribution Channel;
Hospital Pharmacies, Retail Pharmacies, and Online PharmaciesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Pemetrexed Market Overview
Pemetrexed Market (USD Million)
Pemetrexed Market was valued at USD 2,098.25 million in the year 2024. The size of this market is expected to increase to USD 2,919.15 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 4.8%.
Pemetrexed Market
*Market size in USD million
CAGR 4.8 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 4.8 % |
Market Size (2024) | USD 2,098.25 Million |
Market Size (2031) | USD 2,919.15 Million |
Market Concentration | High |
Report Pages | 373 |
Major Players
- Eli Lilly and Company
- Pfizer Inc.
- Fresenius Kabi
- Mylan N.V.
- Accord Healthcare Ltd.
- Teva Pharmaceutical Industries Ltd.
- Dr. Reddy's Laboratories Ltd.
- Sun Pharmaceutical Industries Ltd.
- Hikma Pharmaceuticals PLC
- Aspen Pharmacare Holdings Limited
- Cipla Limited
- Sandoz International GmbH (a subsidiary of Novartis AG)
- Hospira Inc. (a subsidiary of Pfizer Inc.)
- Eagle Pharmaceuticals Inc
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Pemetrexed Market
Fragmented - Highly competitive market without dominant players
The Pemetrexed Market is expanding rapidly due to its increasing use in oncology treatments, particularly for non-small cell lung cancer and mesothelioma. Over 65% of treatment protocols now incorporate pemetrexed, owing to its strong efficacy and patient tolerance. This growing demand is opening up significant opportunities for companies focused on innovative cancer therapies.
Advancements in Drug Formulation
Continual improvements in formulation and drug delivery are contributing to market growth, with more than 58% of new developments centered on advanced injectable formats. These innovations enhance treatment outcomes and patient convenience, prompting new strategies and partnerships across the pharmaceutical ecosystem to accelerate product pipelines.
Strategic Collaborations and Mergers
Around 60% of pharmaceutical firms in this sector are actively engaging in mergers, partnerships, and collaborative ventures. These alliances aim to improve access to biosimilar alternatives and support large-scale production. Such strategic moves are instrumental in driving innovation and ensuring broader market coverage.
Strong Future Outlook for Growth
The pemetrexed market is projected to see robust growth, with more than 62% of companies planning to invest in biosimilar research and clinical studies. With increasing demand for targeted cancer therapies, the sector is poised for sustained expansion. A continued focus on innovation, strategic development, and collaboration will further reinforce its market position.
Pemetrexed Market Recent Developments
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In July 2018, the German Federal Patent Court ruled the German segment of European patent EP 1 313 508 for Alimta invalid. Subsequently, STADAPHARM GmbH, a subsidiary of STADA Arzneimittel AG and an international pharmaceutical company, launched Pemetrexed STADA, a generic version of Alimta, in Europe.
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In February 2022, Dr. Reddy's Laboratories Ltd., a multinational pharmaceutical company along with its subsidiaries, announced a definitive agreement to acquire Nimbus Health GmbH, a privately owned entity.
Pemetrexed Market Segment Analysis
In this report, the Pemetrexed Market has been segmented by Type, Product Type, Strength, Application, Distribution Channel, and Geography.
Pemetrexed Market, Segmentation by Type
The Pemetrexed Market has been segmented by Type into Injectable and Oral.
Injectable
Injectable pemetrexed dominates the market due to its widespread use in hospital-based chemotherapy. It is the primary mode of administration for treating advanced non-squamous non-small cell lung cancer and mesothelioma. This form allows precise dosage control and direct delivery into the bloodstream. Growing hospital admissions for cancer treatment continues to drive its demand globally.
Oral
Although still emerging, oral pemetrexed is gaining attention for its convenience and potential for home-based treatment. It offers easier administration and reduced clinical visits, enhancing patient quality of life. Research and clinical trials are underway to expand its indications. Market growth is anticipated as regulatory approvals progress in key oncology markets.
Pemetrexed Market, Segmentation by Product Type
The Pemetrexed Market has been segmented by Product Type into Branded and Generic.
Branded
Branded pemetrexed products, such as Alimta, dominate in regions with established healthcare infrastructure and favorable reimbursement policies. These products are widely used in hospitals and oncology centers due to their proven clinical efficacy. While more expensive, they remain preferred in critical cancer care. Strong patent portfolios and physician trust help maintain brand loyalty.
Generic
Generic pemetrexed is rapidly gaining traction in cost-sensitive and post-patent markets. These formulations are more affordable and increasingly accepted by healthcare systems aiming to reduce treatment expenditure. Regulatory approvals across Asia Pacific and Latin America are supporting the entry of multiple players. The segment is projected to grow significantly over the forecast period.
Pemetrexed Market, Segmentation by Strength
The Pemetrexed Market has been segmented by Strength into 100 mg and 500 mg.
100 mg
The 100 mg strength is commonly used for low-dose cycles or initial phases of chemotherapy. It is often prescribed in pediatric oncology or for patients with lower body mass. Demand is steady in hospital pharmacies where dose customization is critical. As cancer diagnosis increases in early stages, this strength will remain relevant.
500 mg
500 mg is the most widely used strength for treating advanced lung cancer and mesothelioma. It enables convenient bulk dosing and reduces preparation time in oncology departments. High-volume usage is observed in intensive chemotherapy protocols. The segment continues to dominate due to its alignment with common treatment regimens.
Pemetrexed Market, Segmentation by Application
The Pemetrexed Market has been segmented by Application into Malignant Pleural Mesothelioma and Non-Squamous NSCLC.
Malignant Pleural Mesothelioma
Pemetrexed is a cornerstone drug in the treatment of malignant pleural mesothelioma, often used in combination with cisplatin. Its role in improving survival outcomes is well-documented. This rare cancer segment depends heavily on pemetrexed due to limited alternative treatments. Increasing incidence of asbestos exposure in developing nations sustains demand.
Non-Squamous NSCLC
This is the largest application area for pemetrexed, given its effectiveness in treating advanced-stage non-squamous non-small cell lung cancer. The drug is used in both first-line and maintenance therapies. Rising global lung cancer rates and strong clinical guidelines endorsing pemetrexed support consistent segment expansion. Its use is especially prevalent in developed healthcare markets.
Pemetrexed Market, Segmentation by Distribution Channel
The Pemetrexed Market has been segmented by Distribution Channel into Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies.
Hospital Pharmacies
Hospital pharmacies account for the largest share of pemetrexed distribution due to the drug's use in specialized cancer treatment protocols. On-site availability ensures timely access for inpatients and day-care oncology services. Regulatory compliance and temperature-controlled logistics also support hospital-centric distribution. Expansion of oncology units in tertiary care hospitals drives growth.
Retail Pharmacies
Retail pharmacies are gaining prominence for distributing pemetrexed in outpatient care and follow-up chemotherapy regimens. They serve patients on home-based or maintenance therapy, particularly in regions with decentralized cancer care. Collaborations with healthcare providers improve prescription fulfillment and patient monitoring. This channel is expected to grow with increased outpatient services.
Online Pharmacies
Online pharmacies offer convenient and discreet delivery of pemetrexed, especially in urban areas. As digital health platforms expand, they are playing a key role in cancer drug accessibility. Online channels are particularly useful in countries with well-regulated e-pharmacy frameworks. However, safety concerns and cold chain requirements can be limiting factors.
Pemetrexed Market, Segmentation by Geography
In this report, the Pemetrexed Market has been segmented by Geography into North America, Europe, Asia Pacific, Middle East & Africa, and Latin America.
Regions and Countries Analyzed in this Report
Pemetrexed Market Share (%), by Geographical Region
North America
North America leads the market with a 41.5% share due to its advanced oncology infrastructure and high drug affordability. The U.S. has widespread pemetrexed adoption across all major cancer centers. Reimbursement coverage and early approvals further support growth. Strong clinical research activity sustains market dominance in this region.
Europe
Europe holds a share of approximately 27.8%, driven by increasing cancer prevalence and standardized treatment protocols. Countries like Germany, France, and the UK offer broad access to both branded and generic pemetrexed. Public healthcare reimbursement ensures steady demand. The region also benefits from structured clinical guidelines for oncology drugs.
Asia Pacific
Asia Pacific accounts for 19.2% of the market, with rapid growth fueled by rising lung cancer incidence and expanding healthcare access. China and India are key contributors due to their large populations and increasing availability of generics. Government oncology initiatives and cancer awareness campaigns support market expansion.
Middle East & Africa
This region represents 6.1% of the market and is gradually adopting pemetrexed for advanced cancer care. Growth is concentrated in Gulf countries with investment in specialty hospitals. However, limited insurance coverage and regulatory delays hinder broad adoption in several parts of Africa. Urban oncology networks remain the primary growth zones.
Latin America
Latin America holds a 5.4% share of the global pemetrexed market. Brazil and Mexico lead the region with increasing hospital access and public health initiatives. Demand for generics is rising due to affordability concerns. Challenges include regulatory barriers and inconsistent drug supply chains in remote areas.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Pemetrexed Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers:
- Cancer treatment demand rises
- Growing pharmaceutical advancements
- Increasing clinical research activities
- Expanding oncology drug portfolio
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Rising healthcare investments: In recent years, healthcare investments have been on the rise, spurred by advancements in medical technology, growing demand for quality healthcare services, and an aging population worldwide. This trend is particularly evident in the pharmaceutical sector, where research and development efforts are yielding innovative treatments for various diseases. One such example is the global Pemetrexed market, which has experienced significant growth due to its effectiveness in treating certain types of cancer.
Pemetrexed, a chemotherapy medication, is widely used in the treatment of lung cancer and mesothelioma. The market for Pemetrexed is driven by increasing incidences of these cancers globally, coupled with rising awareness about the availability of advanced treatment options. Additionally, ongoing research and development activities aimed at expanding the application of Pemetrexed in other cancer types are further fueling market growth. With healthcare investments continuing to pour into the development of novel therapies and drugs, the global Pemetrexed market is poised for sustained expansion, offering hope to patients and driving advancements in cancer care.
Restraints:
- Cancer treatment demand rises
- Growing pharmaceutical advancements
- Increasing clinical research activities
- Expanding oncology drug portfolio
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Rising healthcare investments: In recent years, there has been a notable surge in healthcare investments, particularly in the oncology sector, driving significant advancements in cancer treatment and management. Within this landscape, the global Pemetrexed market has experienced remarkable growth. Pemetrexed, a chemotherapy medication used primarily in the treatment of certain types of lung cancer and mesothelioma, has seen increased demand owing to rising cancer incidence rates worldwide. The market expansion can be attributed to several factors, including growing awareness about the efficacy of Pemetrexed in combination therapies, advancements in drug delivery technologies, and expanding healthcare infrastructure in emerging economies.
Ongoing research and development efforts aimed at enhancing the therapeutic efficacy and reducing adverse effects of Pemetrexed are further propelling market growth. Additionally, strategic collaborations between pharmaceutical companies and research institutions are fostering innovation in Pemetrexed-based treatment regimens, driving market competitiveness. With a burgeoning global oncology market and increasing focus on personalized medicine, the Pemetrexed market is poised for continued expansion, offering new hope for patients battling various forms of cancer.
Opportunities:
- Emerging markets offer growth
- Personalized medicine trend boosts
- Novel drug combinations explored
- Enhanced drug delivery technologies
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Collaborations drive innovation: Collaborations indeed serve as catalysts for innovation, and this is profoundly evident in the global Pemetrexed market. Pemetrexed, a chemotherapy medication used in the treatment of certain types of cancer, has witnessed significant advancements and market growth owing to collaborative efforts across various sectors. Pharmaceutical companies, research institutions, and medical professionals have joined forces to enhance the efficacy and accessibility of Pemetrexed-based therapies. Through collaborative research initiatives, scientists have been able to delve deeper into understanding the molecular mechanisms of Pemetrexed action, leading to the development of novel formulations and treatment regimens that offer improved outcomes for patients.
Collaborations have played a pivotal role in expanding the global reach of Pemetrexed, ensuring its availability in diverse healthcare settings worldwide. Partnerships between pharmaceutical firms and regulatory agencies have facilitated the approval and commercialization of Pemetrexed in numerous countries, thereby broadening its market footprint. Additionally, collaborations with advocacy groups and healthcare organizations have raised awareness about Pemetrexed-based therapies, fostering patient education and support initiatives. As a result, the global Pemetrexed market continues to thrive, driven by collaborative endeavors aimed at advancing cancer treatment and improving patient outcomes.
Competitive Landscape Analysis
Key players in Global Pemetrexed Market include:
- Eli Lilly and Company
- Pfizer Inc.
- Fresenius Kabi
- Mylan N.V.
- Accord Healthcare Ltd.
- Teva Pharmaceutical Industries Ltd.
- Dr. Reddy's Laboratories Ltd.
- Sun Pharmaceutical Industries Ltd.
- Hikma Pharmaceuticals PLC
- Aspen Pharmacare Holdings Limited
- Cipla Limited
- Sandoz International GmbH (a subsidiary of Novartis AG)
- Hospira Inc. (a subsidiary of Pfizer Inc.)
- Eagle Pharmaceuticals Inc
In this report, the profile of each market player provides following information
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Product Type
- Market Snapshot, By Strength
- Market Snapshot, By Application
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Region
- Pemetrexed Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Cancer treatment demand rises
- Growing pharmaceutical advancements
- Increasing clinical research activities
- Expanding oncology drug portfolio
- Rising healthcare investments
- Restraints
- Cancer treatment demand rises
- Growing pharmaceutical advancements
- Increasing clinical research activities
- Expanding oncology drug portfolio
- Rising healthcare investments
- Opportunities
- Emerging markets offer growth
- Personalized medicine trend boosts
- Novel drug combinations explored
- Enhanced drug delivery technologies
- Collaborations drive innovation
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
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Pemetrexed Market, By Type, 2021 - 2031 (USD Million)
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Injectable
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Oral
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- Pemetrexed Market, By Product Type, 2021 - 2031 (USD Million)
- Branded
- Generic
- Pemetrexed Market, By Strength, 2021 - 2031 (USD Million)
- 100 mg
- 500 mg
- Pemetrexed Market, By Application, 2021 - 2031 (USD Million)
- Malignant Pleural Mesothelioma
- Non-Squamous NSCLC
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Pemetrexed Market, By Distribution Channel, 2021 - 2031 (USD Million)
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Hospital Pharmacies
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Retail Pharmacies
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Online Pharmacies
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- Pemetrexed Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
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- Competitive Landscape
- Company Profiles
- Eli Lilly and Company
- Pfizer Inc.
- Fresenius Kabi
- Mylan N.V.
- Accord Healthcare Ltd.
- Teva Pharmaceutical Industries Ltd.
- Dr. Reddy's Laboratories Ltd.
- Sun Pharmaceutical Industries Ltd.
- Hikma Pharmaceuticals PLC
- Aspen Pharmacare Holdings Limited
- Cipla Limited
- Sandoz International GmbH (a subsidiary of Novartis AG)
- Hospira Inc. (a subsidiary of Pfizer Inc.)
- Eagle Pharmaceuticals Inc
- Company Profiles
- Analyst Views
- Future Outlook of the Market