Osteoarthritis Treatment Market
By Route of Administration;
Oral, Parenteral, and OthersBy Drug Type;
Prescription Drugs and Over-the-Counter DrugsBy Treatment;
NSAID’s, Corticosteroids, and AnalgesicsBy Anatomy;
Knee Osteoarthritis, Hip Osteoarthritis, Hand Osteoarthritis, and Small Joint OsteoarthritisBy Distribution Channel;
Hospital Pharmacies, Retail Pharmacies, and Online PharmaciesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Osteoarthritis Treatment Market Overview
Osteoarthritis Treatment Market (USD Million)
Osteoarthritis Treatment Market was valued at USD 9,828.56 million in the year 2024, the Gl. The size of this market is expected to increase to USD 17,680.52 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 8.8%.
Osteoarthritis Treatment Market
*Market size in USD million
CAGR 8.8 %
Study Period | 2025 - 2031 |
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Base Year | 2024 |
CAGR (%) | 8.8 % |
Market Size (2024) | USD 9,828.56 Million |
Market Size (2031) | USD 17,680.52 Million |
Market Concentration | Medium |
Report Pages | 359 |
Major Players
- AstraZeneca
- Johnson & Johnson Private limited
- Pfizer
- Teva Pharmaceuticals
- Reckitt Benckiser Group plc.
- Sun Pharmaceutical Industries Ltd.
- Bayer AG
- Perrigo Company
- Tolmar Pharmaceuticals
- Sanofi
- Horizon Therapeutics
- Boehringer Ingelheim International GmbH.
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Osteoarthritis Treatment Market
Fragmented - Highly competitive market without dominant players
The Osteoarthritis Treatment Market is gaining traction as one of the most significant healthcare segments, with 12–15% of the global population affected by this degenerative joint condition. Its prevalence rises sharply with age, and nearly 40% of individuals above 65 years report symptoms. As a leading cause of mobility loss, rising awareness of joint health and access to advanced care are boosting treatment adoption.
Pharmacological Treatments Driving Adoption
Drug-based therapies remain the foundation of osteoarthritis management, with over 60% of patients relying on NSAIDs, corticosteroids, and novel disease-modifying agents. Biologics are emerging as transformative solutions, delivering ~25% higher treatment success rates than conventional medicines. This reflects a growing emphasis on precision-based, patient-specific approaches.
Non-Pharmacological Therapies Enhancing Outcomes
Complementary methods like physiotherapy, exercise, and lifestyle adjustments represent 30–35% of overall treatment regimens. These strategies help reduce pain intensity by ~20% while improving joint mobility, especially for early-stage patients. Their integration with drug therapies ensures a more holistic and sustainable care model.
Innovative Treatment Approaches Transforming Care
Advances in regenerative medicine and minimally invasive techniques are reshaping therapeutic standards. Stem cell therapies and platelet-rich plasma procedures demonstrate ~35% better functional outcomes than conventional care. Growing adoption of these innovations highlights the demand for restorative and long-lasting solutions.
Osteoarthritis Treatment Market Recent Developments
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In September 2022, Alkem Laboratories received approval from the Drug Controller General of India (DCGI) for StemOne, an off-the-shelf cell therapy developed in collaboration with Stempeutics. This groundbreaking product is aimed at treating knee osteoarthritis, a common degenerative joint disease in India, marking a significant advancement for Alkem in the field of regenerative medicine.
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In August 2022, Shionogi & Co., Ltd. and Grünenthal GmbH concluded a licensing agreement to introduce injectable resiniferatoxin, a promising product from Grünenthal's pipeline, to the Japanese market. This innovative therapy is designed to provide pain relief for patients with knee osteoarthritis, addressing an unmet need in Japan’s medical landscape with a novel approach to pain management.
Osteoarthritis Treatment Market Segment Analysis
In this report, the osteoarthritis treatment market has been segmented by Route of Administration, Drug Type, Treatment, Anatomy, Distribution Channel and geography.
Osteoarthritis Treatment Market, Segmentation by Route of Administration
The Osteoarthritis Treatment Market has been segmented by Drugs into Route of Administration Oral, Parenteral, and Others.
Oral
The oral route accounts for roughly 55% of osteoarthritis prescriptions, reflecting its convenience for stepwise, chronic care. Emphasis on patient adherence and long-term safety supports the use of non-invasive dosing in primary and specialty settings. Advances in extended-release formulations and combination regimens are enhancing symptom control with streamlined routines.
Parenteral
Parenteral delivery represents about 40% of administered therapies, led by injectable therapies used for targeted, rapid relief. Utilization is reinforced by protocols that prioritize procedure-guided dosing and monitoring for difficult-to-manage pain. Growth in clinic-based services and biologic interventions is supporting sustained outcomes in moderate to severe cases.
Others
The others segment comprises near 5%, including topical analgesics, transdermal systems, and supportive products for localized relief. These options are favored in patients requiring non-systemic management or adjunct therapy alongside systemic drugs. Innovation in drug-delivery technologies is broadening access to personalized regimens with fewer systemic effects.
Osteoarthritis Treatment Market, Segmentation by Drug Type
The Osteoarthritis Treatment Market has been segmented by Drug Type into Prescription Drugs and Over-the-Counter Drugs.
Prescription Drugs
Prescription therapies account for about 60% of osteoarthritis treatment value, driven by physician-directed efficacy standards and monitored dosing. Growth is supported by broader reimbursement coverage and step-up use in moderate to severe cases. Emphasis on real-world safety tracking and treatment adherence is improving long-term outcomes across care settings.
Over-the-Counter Drugs
Over-the-counter options represent roughly 40% of utilization, favored for accessible self-management and rapid symptom relief. Adoption is boosted by wide retail availability of topical analgesics and oral pain relievers, particularly in early-stage disease. Increasing consumer education and pharmacist-led guidance are enhancing appropriate use and persistence.
Osteoarthritis Treatment Market, Segmentation by Treatment
The Osteoarthritis Treatment Market has been segmented by Treatment into NSAID’s, Corticosteroids, and Analgesics.
NSAID’s
NSAID’s account for approximately 50% of osteoarthritis treatments, widely used for their anti-inflammatory and pain-relieving effects. They are a preferred first-line therapy for mild to moderate cases, with growing use of selective COX-2 inhibitors to reduce gastrointestinal risks. Advances in formulation technology are improving safety profiles and patient tolerance.
Corticosteroids
Corticosteroids represent about 30% of the market, primarily administered through intra-articular injections for targeted symptom control. They offer rapid relief in acute flare-ups, particularly in advanced disease stages. Increasing adoption of image-guided delivery is enhancing precision and reducing adverse effects.
Analgesics
Analgesics hold close to 20% of the market, used for pain management in patients who cannot tolerate NSAID’s or require adjunct therapy. This category includes both opioid and non-opioid formulations, with a focus on minimizing dependency risks. Expansion of multi-modal pain strategies is supporting better patient outcomes and quality of life.
Osteoarthritis Treatment Market, Segmentation by Geography
In this report, the Osteoarthritis Treatment Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East & Africa and Latin America.
Regions and Countries Analyzed in this Report
Osteoarthritis Treatment Market Share (%), by Geographical Region
North America
North America holds about 42% of the osteoarthritis treatment market, supported by advanced healthcare infrastructure and early adoption of innovative therapies. High awareness levels and strong reimbursement policies contribute to faster diagnosis and better treatment access across the region.
Europe
Europe accounts for nearly 28% of the market, driven by robust public health programs and a well-established network of orthopedic specialists. Focus on patient-centric care and advancements in minimally invasive treatments are improving long-term mobility outcomes.
Asia Pacific
Asia Pacific represents close to 20% of the market, with growth fueled by a rising elderly population and increased healthcare spending. Expansion of specialized medical centers and wider access to affordable treatments are enhancing patient care standards in the region.
Middle East & Africa
The Middle East & Africa segment captures around 6% of the market, supported by improvements in hospital infrastructure and rising awareness of joint health. Government-led health initiatives are promoting early intervention and advanced therapy adoption.
Latin America
Latin America holds approximately 4% of the market, driven by gradual improvements in orthopedic care and expanding insurance coverage. Increased availability of cost-effective treatments is improving accessibility for a larger patient population.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Osteoarthritis Treatment Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers
- Increasing Prevalence of Obesity
- Rising Awareness and Diagnosis
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Patient-Centric Care- In the context of osteoarthritis, patient-centric care encompasses various aspects that prioritize the overall well-being and quality of life of patients, going beyond solely managing symptoms to address the physical, emotional, and social aspects of the condition. One key aspect of patient-centric care in the osteoarthritis treatment market is personalized treatment planning. Healthcare providers recognize that osteoarthritis affects individuals differently, with variations in symptom severity, disease progression, comorbidities, and treatment response. As such, adopting a personalized approach to treatment involves conducting comprehensive assessments to understand each patient's unique circumstances, preferences, and treatment goals. This may involve considering factors such as age, functional status, lifestyle, comorbidities, medication tolerance, and patient preferences for treatment modalities. Furthermore, patient education and empowerment are integral components of patient-centric care in the osteoarthritis treatment market. Educating patients about their condition, treatment options, self-management strategies, and lifestyle modifications empowers them to actively participate in decision-making regarding their care. By fostering patient understanding and engagement, healthcare providers enable patients to make informed choices that align with their values, preferences, and treatment goals. Patient education also helps promote adherence to treatment regimens, encourage lifestyle modifications, and facilitate shared decision-making between patients and healthcare providers. Additionally, patient-centric care in the osteoarthritis treatment market extends beyond medical management to encompass holistic support for patients' physical, emotional, and social well-being. This may involve providing access to multidisciplinary care teams comprising healthcare professionals such as rheumatologists, orthopedic surgeons, physical therapists, occupational therapists, nutritionists, and mental health professionals. Collaborative care teams work together to address the diverse needs of patients, offering a comprehensive range of services aimed at improving functional status, reducing pain, enhancing mobility, and optimizing overall quality of life.
Moreover, patient-centric care emphasizes the importance of ongoing communication, support, and follow-up to monitor treatment progress, address concerns, and adjust treatment plans as needed. Regular communication between patients and healthcare providers facilitates the timely identification of treatment response, adverse effects, or changes in disease status, allowing for prompt intervention and optimization of care. By fostering open and transparent communication, healthcare providers can build trust, rapport, and therapeutic relationships with patients, enhancing patient satisfaction and engagement in their care.
Restraints
- Limited Efficacy of Current Treatments
- Safety Concerns and Side Effects
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Limited Treatment Options for Severe Cases- While various pharmacological and non-pharmacological interventions are available for managing mild to moderate osteoarthritis symptoms, options for individuals with severe osteoarthritis are more limited and often inadequate. Severe osteoarthritis is characterized by advanced joint damage, debilitating pain, significant functional impairment, and decreased quality of life. Unfortunately, existing treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, analgesics, and physical therapy may provide only partial relief or have limited efficacy in severe cases. One of the primary challenges in treating severe osteoarthritis is the lack of disease-modifying therapies that can halt or reverse the progression of joint degeneration. While disease-modifying osteoarthritis drugs (DMOADs) are an area of active research, few options are currently available for clinical use. Additionally, surgical interventions such as joint replacement surgery (arthroplasty) may be necessary for severe osteoarthritis patients who have exhausted conservative treatment options. However, surgery carries inherent risks, requires significant recovery time, and may not be suitable for all patients.
Another constraint is the limited availability of effective pain management strategies for severe osteoarthritis. Chronic pain associated with severe osteoarthritis can significantly impact a patient's quality of life and functional abilities. While opioids are sometimes prescribed for severe pain, their long-term use carries risks of addiction, tolerance, and adverse effects. Moreover, many patients with severe osteoarthritis may have comorbidities or contraindications that limit the use of certain medications or treatment modalities. Furthermore, access to specialized healthcare services and multidisciplinary care may be limited for individuals with severe osteoarthritis, particularly in underserved regions or healthcare systems with resource constraints. Comprehensive management of severe osteoarthritis often requires a multidisciplinary approach involving rheumatologists, orthopedic surgeons, pain specialists, physical therapists, and other healthcare professionals. However, access to such integrated care may be challenging due to barriers such as geographical distance, financial constraints, or lack of specialized facilities.
Opportunities
- Rising Awareness and Diagnosis
- Expanding Treatment Options
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Regulatory Support and Incentives- Regulatory agencies worldwide, such as the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the Pharmaceuticals and Medical Devices Agency (PMDA) in Japan, are increasingly recognizing the need to expedite the development and approval of innovative treatments for osteoarthritis. These agencies offer various regulatory pathways and incentives to facilitate faster market entry and commercialization of novel therapies, thereby encouraging investment in osteoarthritis research and development. One significant opportunity provided by regulatory support is the availability of expedited pathways for drug approval. Regulatory agencies offer programs such as the FDA's Fast Track, Breakthrough Therapy, and Priority Review designations, which aim to accelerate the development and review of promising treatments for serious or life-threatening conditions, including osteoarthritis. By expediting the regulatory review process, these pathways enable pharmaceutical companies to bring new osteoarthritis treatments to market more quickly, addressing unmet medical needs and improving patient access to innovative therapies. Furthermore, regulatory agencies may grant orphan drug designations for novel treatments targeting rare diseases or conditions, including subsets of osteoarthritis. Orphan drug status provides companies with incentives such as extended market exclusivity, tax credits for research and development expenses, and protocol assistance from regulatory agencies. These incentives encourage investment in the development of innovative osteoarthritis treatments for specific patient populations, where traditional market incentives may be lacking.
Moreover, regulatory support extends to the approval of biosimilar products for osteoarthritis treatment. Biosimilars are biologic drugs that are highly similar to an already approved biologic reference product, offering cost-effective alternatives for patients. Regulatory agencies have established pathways for the approval of biosimilars, providing opportunities for competition and market access, which can lead to lower treatment costs and increased affordability for osteoarthritis patients.
Competitive Landscape Analysis
Key players in Global Osteoarthritis Treatment Market include:
- AstraZeneca
- Johnson & Johnson Private limited
- Pfizer
- Teva Pharmaceuticals
- Reckitt Benckiser Group plc.
- Sun Pharmaceutical Industries Ltd.
- Bayer AG
- Perrigo Company
- Tolmar Pharmaceuticals
- Sanofi
- Horizon Therapeutics
- Boehringer Ingelheim International GmbH.
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Route of Administration
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Market Snapshot, By Drug Type
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Market Snapshot, By Treatment
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Market Snapshot, By Anatomy
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Market Snapshot, By Distribution Channel
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Market Snapshot, By Region
- Osteoarthritis Treatment Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
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Increasing Prevalence of Obesity
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Rising Awareness and Diagnosis
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Patient-Centric Care
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- Restraints
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Limited Efficacy of Current Treatments
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Safety Concerns and Side Effects
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Limited Treatment Options for Severe Cases
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- Opportunities
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Rising Awareness and Diagnosis
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Expanding Treatment Options
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Regulatory Support and Incentives
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- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Osteoarthritis Treatment Market, By Route of Administration, 2021 - 2031 (USD Million)
- Oral
- Parenteral
- Others
- Osteoarthritis Treatment Market, By Drug Type, 2021 - 2031 (USD Million)
- Prescription Drugs
- Over-the-Counter Drugs
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Osteoarthritis Treatment Market, By Treatment, 2021 - 2031 (USD Million)
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NSAID’s
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Corticosteroids
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Analgesics
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- Osteoarthritis Treatment Market, By Anatomy, 2021 - 2031 (USD Million)
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Knee Osteoarthritis
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Hip Osteoarthritis
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Hand Osteoarthritis
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Small Joint Osteoarthritis
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- Osteoarthritis Treatment Market, By Distribution Channel, 2021 - 2031 (USD Million)
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Hospital Pharmacies
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Retail Pharmacies
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Online Pharmacies
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- Osteoarthritis Treatment Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Osteoarthritis Treatment Market, By Route of Administration, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
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AstraZeneca
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Johnson & Johnson Private limited
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Pfizer
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Teva Pharmaceuticals
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Reckitt Benckiser Group plc.
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Sun Pharmaceutical Industries Ltd.
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Bayer AG
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Perrigo Company
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Tolmar Pharmaceuticals
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Sanofi
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Horizon Therapeutics
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Boehringer Ingelheim International GmbH.
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- Company Profiles
- Analyst Views
- Future Outlook of the Market