Global Organ Preservation Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

• In January 2023, transplant surgeons at MedStar Georgetown University Hospital in the Washington Metropolitan area, United States, successfully leveraged the newly FDA-approved OrganOx metra system to enhance liver transplantation procedures. This innovative technology mimics the physiological conditions of a human body by simulating the connection between a donated liver and its recipient. With the use of the OrganOx metra, the donated liver can now be preserved for up to 12 hours before transplantation, significantly improving the organ’s viability and offering greater flexibility for surgical planning and recipient matching.

• In August 2022, Paragonix Technologies, Inc. achieved a major milestone by successfully preserving over 2,000 donor organs through the use of its Advanced Organ Preservation (AOPT) technology and an extensive statewide clinical support network. The company's innovative preservation systems, which feature first-of-their-kind methods, have delivered a significant advancement over traditional ice-and-cooler practices. By enhancing organ viability and safety during transport, Paragonix’s technologies are helping transplant hospitals improve patient outcomes and optimize transplantation success rates.

• In January 2022, OrganOx, a university spinoff and global leader in normothermic machine perfusion (NMP) technology, announced that it had received Premarket Approval (PMA) from the U.S. Food and Drug Administration (FDA) for its groundbreaking OrganOx metra system. Developed by researchers specializing in Biomedical Engineering and Surgery, the OrganOx metra represents a major advancement in organ preservation technology, offering a revolutionary approach to maintaining donor organ viability outside the body through normothermic conditions.

In this report, the Global Organ Preservation Market has been segmented by Preservation Soultion, Technique, Organ, End-User, and Geography.

Global Organ Preservation Market, Segmentation by Preservation Soultion

The Global Organ Preservation Market has been segmented by Preservation Soultion into Intracellular Solutions, Extracellular Solutions, Colloids, and Others.

Intracellular Solutions
Intracellular solutions continue to lead the global organ preservation market, accounting for nearly 45% of total revenue. Their composition closely mirrors the cellular interior, effectively minimizing cellular injury during cold storage. These solutions are predominantly used for preserving kidneys and livers, making them a cornerstone in static preservation methods, especially in high-volume transplant centers.

Extracellular Solutions
With a market share of approximately 30%, extracellular solutions are widely used in the preservation of hearts and lungs. These fluids replicate the extracellular environment, supporting osmotic stability and reducing the risk of edema. Their rising popularity is also attributed to increasing applications in normothermic and hypothermic machine perfusion systems, particularly for thoracic organ transplants.

Colloids
Colloidal preservation fluids, which include agents like dextran and hydroxyethyl starch, contribute roughly 15% to the global market. These solutions play a pivotal role in maintaining oncotic pressure and preventing cellular swelling, particularly during prolonged storage. They are often used in conjunction with other preservation methods to improve outcomes in complex transplant procedures.

Others
The "Others" category, comprising about 10% of the market, includes emerging and experimental preservation solutions. These may involve cryoprotective agents, novel perfusates, or customized fluids tailored for advanced or rare transplant procedures. This segment is expected to grow steadily as research continues into new preservation strategies that extend viability and improve organ quality during transportation.

Global Organ Preservation Market, Segmentation by Technique

The Global Organ Preservation Market has been segmented by Technique into Static Cold Storage (SCS) Technique , Hypothermic Machine Perfusion, and Normothermic Machine Perfusion.

Static Cold Storage (SCS): The Traditional Standard
Static Cold Storage (SCS) continues to serve as the cornerstone of organ preservation globally, accounting for more than 80% of transplantation procedures. This conventional method involves immersing the organ in a cold preservation solution to suppress metabolic activity and prevent cellular damage. SCS is valued for its cost-efficiency and ease of implementation, making it particularly beneficial in resource-constrained settings. However, it comes with notable drawbacks, including limited preservation duration—generally under 12 hours—and the potential for tissue damage during the rewarming phase.

Hypothermic Machine Perfusion (HMP): Enhancing Viability
Hypothermic Machine Perfusion (HMP) has emerged as a superior alternative to SCS, currently applied in around 10-15% of preservation scenarios. This method involves continuously perfusing the organ with a chilled preservation solution while maintaining precise control over pressure and temperature. HMP significantly improves organ viability, extends preservation times, and enables better post-transplant outcomes. It is especially advantageous for marginal organs or extended criteria donors, where maintaining quality is critical for transplant success.

Normothermic Machine Perfusion (NMP): Transforming Transplantation
Normothermic Machine Perfusion (NMP) is the latest innovation in the organ preservation landscape, with early adoption seen in approximately 5% of cases. Unlike cold-based techniques, NMP maintains organs at near-physiological temperatures, simulating natural conditions using oxygenated blood or specialized fluids. This enables ongoing cellular repair and metabolic activity, allowing for ex vivo evaluation and optimization. Studies suggest NMP could expand the transplantable organ pool by up to 25%, positioning it as a transformative solution to meet growing global transplant demands.

Global Organ Preservation Market, Segmentation by Organ

The Global Organ Preservation Market has been segmented by Organ into Kidney , Liver , Lung , Heart, and Others.

Kidney: Leading the Organ Preservation Demand
The kidney segment remains the largest contributor to the organ preservation market, representing about 50% of global usage. This is primarily due to the high global burden of end-stage renal disease and the widespread need for kidney transplants. As more than 70% of transplant procedures involve kidneys, the availability of specialized kidney preservation solutions has played a key role in improving success rates and expanding donor utilization.

Liver: High Demand Fueled by Liver Diseases
Liver preservation solutions hold a significant share of the market, accounting for approximately 25%. Rising rates of liver-related illnesses such as cirrhosis, hepatitis, and liver cancer have increased the need for liver transplants worldwide. Innovations in preservation techniques have extended liver viability and contributed to better post-transplant outcomes, propelling steady market growth.

Heart and Lung: Emerging Segments with Strong Potential
Together, heart and lung preservation solutions make up nearly 20% of the global market. The increase in cardiovascular and respiratory diseases has led to a notable rise in heart and lung transplant procedures. Advanced techniques such as machine perfusion systems are enhancing organ quality and supporting transplant success, especially for high-risk and marginal donor cases.

Cross-Segment Growth Outlook
Research efforts continue to focus on refining preservation technologies for all organ types. These advancements aim to extend preservation times, minimize damage, and improve transplant viability—ultimately driving holistic growth across kidney, liver, heart, and lung segments in the years ahead.

Global Organ Preservation Market, Segmentation by End-User

The Global Organ Preservation Market has been segmented by End-User Soultion into Hospitals and Clinics, Organ Banks, and Others.

Hospitals and Clinics: Primary End-Users in Organ Preservation
Hospitals and clinics remain the largest end-user segment in the organ preservation market, contributing to over 60% of global usage. These facilities are directly involved in transplantation procedures and depend on effective preservation solutions—such as static cold storage and machine perfusion—to ensure organ viability during the crucial period between donor recovery and transplantation. Given the urgency of transplant operations, reliable preservation is vital to achieving successful patient outcomes. Many hospitals are also engaged in research activities to improve organ storage techniques and prolong viability.

Organ Banks: Ensuring Organ Quality and Coordination
Organ banks hold a significant share of approximately 25% in the market, functioning as specialized centers for the storage and distribution of donor organs. These institutions use advanced technologies and preservation fluids to ensure optimal organ conditions until they are matched with recipients. In addition to storage, organ banks play a central role in coordinating logistics between hospitals, transplant teams, and procurement networks, making them essential to maintaining the overall quality and timing of transplant procedures.

Other End-Users: Driving Research and Development
The remaining 15% of the market includes Organ Procurement Organizations (OPOs), research institutions, and biotech firms. OPOs are responsible for recovering organs and facilitating transport logistics. Research institutions and biotechnology companies contribute through innovation, conducting trials and developing advanced preservation methods. Their efforts are crucial to expanding the number of viable organs available for transplant, ultimately addressing the growing global demand for transplantation.

Global Organ Preservation Market, Segmentation by Geography

In this report, the Global Organ Preservation Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East & Africa, and Latin America.

Global Organ Preservation Market Share (%), by Geographical Region, 2024

North America
North America dominates the global organ preservation market, capturing nearly 40% of the total share. This leadership is driven by a robust healthcare infrastructure, high frequency of organ transplants, and early adoption of cutting-edge preservation techniques. The region is home to several major industry players and benefits from supportive government policies aimed at boosting organ donation and transplantation initiatives.

Europe
Europe contributes close to 30% of the global market, supported by widespread public awareness and strong regulatory frameworks promoting organ donation. With ongoing R&D in dynamic preservation systems such as hypothermic and normothermic perfusion, Europe continues to lead in technological innovation. Countries like Germany, the UK, and Spain are at the forefront of developing sustainable preservation practices.

Asia Pacific
Asia Pacific holds around 15% of the global market and is expected to grow at the fastest rate in the coming years. Rapidly increasing healthcare expenditures, a growing patient base for organ transplants, and rising awareness are driving demand for preservation solutions. Nations such as China, India, and Japan are investing heavily in improving transplant capabilities and infrastructure.

Middle East & Africa
The Middle East & Africa currently represents about 8% of the organ preservation market. While the region faces challenges like limited access to advanced healthcare, growing awareness and gradual improvements in medical infrastructure are supporting modest growth. Efforts are underway in countries like the UAE and South Africa to strengthen transplant systems and increase donor registrations.

Latin America
Latin America accounts for approximately 7% of global demand, with growth centered in Brazil, Mexico, and Argentina. Government initiatives and increasing cross-border collaborations are supporting market expansion. While infrastructure limitations persist, ongoing health reforms and awareness campaigns are creating new opportunities for the adoption of advanced preservation techniques.

This report provides an in depth analysis of various factors that impact the dynamics of Global Organ Preservation Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.

Drivers:

• Aging population
• Organ shortage
• Technological advancements
• Increased transplant surgeries

• Rising prevalence of chronic diseases- The global organ preservation market is experiencing significant growth, largely due to the increasing prevalence of chronic diseases across the world. Conditions like cardiovascular diseases, diabetes, kidney failure, and liver diseases are on the rise, often attributed to factors such as unhealthy diets, sedentary lifestyles, and aging populations. These diseases frequently lead to organ failure, which creates a greater demand for organ transplants as a life-saving treatment. As the demand for organs outpaces the availability of suitable donors, advanced organ preservation technologies play a crucial role in maintaining organ viability during transportation and storage, improving the likelihood of successful transplants. This growing need for effective preservation solutions is spurring innovation and investment, which has led to the development of more efficient preservation techniques and devices that enhance organ quality and transplant outcomes.

  Medical technology and research advancements have revolutionized organ preservation, facilitating the development of new techniques that extend preservation times and enhance organ viability. Notable innovations include machine perfusion systems—hypothermic and normothermic perfusion systems—that offer superior organ preservation by maintaining ideal conditions for organ function outside the body. These technologies not only increase the duration organs can be preserved but also allow for organ viability assessments prior to transplantation, thereby reducing the risks of graft failure and rejection.

  The increased adoption of organ preservation technologies is also driven by the expansion of organ procurement and transplantation programs worldwide. Government initiatives, along with collaborations between healthcare organizations and research institutions, have helped address the growing demand for organs. These efforts are vital for ensuring that the right preservation methods are in place to improve transplant success rates and, ultimately, patient outcomes.With these advancements and a rising demand for organ preservation solutions, the market for organ preservation is expected to continue its rapid growth, helping meet the increasing need for organ transplants globally.

Restraints:

• Limited organ preservation methods
• Regulatory challenges
• High cost of organ preservation
• Lack of awareness

• Ethical concerns- The rapid advancement of organ preservation technologies has opened new possibilities in organ transplantation, offering hope to millions of patients in need of life-saving transplants. However, this progress also brings forth significant ethical issues. One of the most pressing ethical dilemmas involves the allocation of preserved organs. Given that the demand for organs far outweighs the supply, questions about the fairness of distribution inevitably arise. Should organ allocation be based on medical urgency, the recipient's socioeconomic status, or other criteria? As the principles of justice, beneficence, and autonomy come into play, determining who should receive these limited resources becomes an increasingly complex issue.

  Ethical considerations in organ preservation extend beyond the allocation process to the very methods used for organ storage and viability extension. As preservation technologies evolve to prolong organ life outside the body, they raise significant questions about the definition of death and the ethics of intervening in the natural dying process. Prolonged preservation of organs calls into question the boundaries between life and death, especially when these advancements challenge traditional views on the timing of organ donation.

  Additionally, ensuring that informed consent is obtained from organ donors becomes crucial as preservation techniques continue to advance. The ethical concerns of respecting the autonomy of donors grow as the line between organ donation and the potential commodification of human body parts becomes increasingly blurred. With the expansion of the global organ preservation market, addressing these ethical challenges will require ongoing conversations, transparency, and a strong commitment to ethical principles like beneficence, non-maleficence, and justice. These principles are vital to ensuring that patient outcomes are improved while upholding the dignity and rights of donors.

Opportunities:

• Emerging markets
• Development of novel preservation solutions
• Collaborations and partnerships
• Focus on personalized medicine

• Growing medical tourism industry- The global organ preservation market is witnessing substantial growth, driven primarily by advancements in medical technology and a rising global demand for organ transplantation procedures. Organ preservation solutions are essential in maintaining the viability of organs during storage and transportation, ensuring they remain suitable for transplantation. As incidents of organ failure increase, and with a growing aging population, the need for organ transplants continues to rise, further intensifying the demand for effective organ preservation methods.

  The rapid expansion of the medical tourism industry is also playing a significant role in the growth of the organ preservation market. Patients from developed nations are increasingly traveling to emerging economies where affordable medical treatments, including organ transplant procedures, are available. This trend is particularly prominent in countries with lower healthcare costs but high-quality medical infrastructure and skilled healthcare professionals. As a result, the demand for advanced organ preservation solutions is anticipated to increase in regions popular for medical tourism, spurring further market growth and technological innovation.

  The global organ preservation market is expanding due to the synergy between technological progress, the rising need for organ transplants, and the growth of the medical tourism industry. As these factors converge, the market for organ preservation technologies is expected to see continued growth, providing innovative solutions to meet the increasing demand for organ transplants worldwide.

Key players in Global Organ Preservation Market include:

• XVIVO Perfusion AB
• Organ Recovery Systems, Inc
• Preservation Solutions, Inc
• TransMedics, Inc
• Waters Medical Systems LLC
• OrganOx Limited
• Bridge to Life Ltd
• OrganAssist BV
• Essential Pharmaceuticals LLC
• 21st Century Medicine Inc

In this report, the profile of each market player provides following information:

• Company Overview and Product Portfolio
• Key Developments
• Financial Overview
• Strategies
• Company SWOT Analysis