Global Kidney Stone Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

• In January 2022, Applaud Medical, Inc. achieved a major milestone in the field of kidney stone treatment with the recognition of its innovative Acoustic Enhancer technology. The U.S. Food and Drug Administration (FDA) granted the technology Breakthrough Device designation, highlighting its potential to offer significant clinical benefits over existing treatment options. This designation underscores the company’s commitment to advancing non-invasive solutions and accelerating the development of technologies that can improve patient outcomes in kidney stone management. The Acoustic Enhancer is designed to work alongside traditional procedures, enhancing stone fragmentation and boosting treatment efficacy.

• In July 2022, Calyxo announced a significant financial breakthrough by raising USD 32 million in funding to advance its novel vacuum-assisted device for kidney stone treatment. This innovative technology is specifically engineered to efficiently remove kidney stone fragments, improving procedural outcomes and reducing the risk of residual debris. The funding will support further development, clinical validation, and commercialization efforts, positioning Calyxo as a key player in the evolving urology device landscape. The solution addresses a critical gap in post-fragmentation stone clearance, enhancing both effectiveness and patient recovery.

In this report, the Global Kidney Stone Market has been segmented by Types, Treatment, Diagnosis, and Geography.

Global Kidney Stone Market, Segmentation by Types

The Global Kidney Stone Market has been segmented by Types into Calcium Oxalate Stones , Uric Acid , Struvite Kidney Stones , Cystine Stones, and Calcium Phosphate Stones .

Calcium oxalate stones are the most common type of kidney stones, accounting for approximately 70-80% of all cases. These stones form when calcium combines with oxalate in the urine. Factors such as dehydration, high oxalate levels in the diet, and genetic predisposition increase the likelihood of forming these stones. As the most prevalent type, calcium oxalate stones remain a primary focus in both treatment and prevention strategies in the kidney stone market.

Uric acid stones make up about 5-10% of all kidney stone cases. These stones occur when there is an excess of uric acid in the urine, often due to conditions like gout or dehydration. Uric acid stones are more common in individuals with high-protein diets or metabolic disorders. As this type of stone is less common, it requires specialized treatments, including medications to lower uric acid levels and dietary modifications to reduce the risk of formation.

Struvite kidney stones represent approximately 10-15% of all kidney stone cases. These stones typically form as a result of urinary tract infections caused by specific bacteria that produce ammonia, leading to the formation of struvite. Struvite stones are more common in women, especially those with recurrent urinary tract infections. Treatment often involves antibiotics and surgical procedures to remove the stones, along with preventive measures to manage infections.

Cystine stones account for about 1-2% of all kidney stone cases. They are a rare genetic condition caused by an inherited disorder that leads to an accumulation of cystine in the urine. These stones can form in individuals who have a high concentration of cystine in their urine, which is usually due to a metabolic disorder. Cystine stones require specialized treatment, including increased fluid intake, medications to prevent stone formation, and in some cases, surgical intervention.

Calcium phosphate stones represent approximately 5-10% of kidney stones. They typically form in conditions where there is an imbalance of calcium and phosphate in the urine. These stones are often associated with metabolic disorders, kidney diseases, or certain medications that alter the levels of calcium and phosphate. Prevention and treatment focus on controlling underlying health conditions, increasing fluid intake, and sometimes using medications that help balance calcium and phosphate levels.

Global Kidney Stone Market, Segmentation by Treatment

The Global Kidney Stone Market has been segmented by Treatment into Medications, Extracorporeal Shock Wave Lithotripsy , Ureteroscopy, and Percutaneous Nephrolithotomy.

Medications play a significant role in the treatment of kidney stones, accounting for approximately 30% of the global market. These treatments include drugs that help prevent stone formation, such as thiazide diuretics for calcium stones or allopurinol for uric acid stones. Medications are also used to relieve pain during stone passage and help facilitate the dissolution of smaller stones. The use of pharmacological treatments is growing due to increased awareness of less invasive solutions and a focus on preventive care.

Extracorporeal Shock Wave Lithotripsy (ESWL) is one of the most widely used non-invasive procedures, representing about 40% of the kidney stone treatment market. This method uses high-energy shock waves to break down kidney stones into smaller pieces, which can then be passed more easily through the urinary tract. ESWL is preferred for treating stones located in the kidneys and upper urinary tract, especially for patients who are not candidates for surgery. The market for ESWL continues to grow as it is a relatively safe, effective, and well-established treatment.

Ureteroscopy accounts for around 15% of the market share in kidney stone treatments. This procedure involves the use of a small camera, or ureteroscope, to locate and remove stones from the urinary tract. Ureteroscopy is particularly effective for treating stones located in the ureters. The procedure is minimally invasive, and with advancements in technology, it has become a preferred choice for many patients due to its precision and relatively low risk of complications.

Percutaneous Nephrolithotomy (PCNL) represents approximately 10-15% of the kidney stone treatment market. This is a minimally invasive surgical procedure used to treat large or complex kidney stones. The procedure involves creating a small incision in the back and inserting a nephroscope to remove the stones. PCNL is highly effective for large stones and is often used when other treatments, such as ESWL, are ineffective. As the demand for advanced surgical solutions increases, the market for PCNL continues to grow steadily.

Global Kidney Stone Market, Segmentation by Diagnosis

The Global Kidney Stone Market has been segmented by Diagnosis into Ultrasound, Intravenous Pyelography (IVP) Or Intravenous Urogram, CT Scan, X-Ray, and Others .

Ultrasound is one of the most common diagnostic tools for kidney stones, accounting for approximately 25% of the market. It is a non-invasive and cost-effective imaging method that helps identify kidney stones through sound waves. Ultrasound is especially useful for detecting stones in the kidneys or urinary tract, providing real-time results with minimal discomfort for the patient. Its widespread adoption, particularly in routine checkups and emergency settings, contributes to its steady market share.

Intravenous Pyelography (IVP) or Intravenous Urogram is responsible for about 20% of the global kidney stone diagnostic market. This diagnostic procedure involves injecting a contrast dye into the bloodstream, which helps outline the kidneys, ureters, and bladder on X-ray images. IVP is useful for detecting stones in the urinary tract and evaluating the function of the kidneys. Despite being less commonly used than newer imaging techniques, it remains valuable in specific clinical situations.

CT scans hold the largest share in the kidney stone diagnostic market, with approximately 40% market dominance. This imaging technique provides detailed cross-sectional images, making it highly effective for detecting and locating kidney stones, especially for stones that may not be visible with other methods. CT scans are known for their high accuracy and precision, which makes them the preferred choice in emergency and severe cases. Their growing usage is driven by advancements in technology that enhance speed and reduce radiation exposure.

X-rays represent about 10% of the market for kidney stone diagnosis. X-rays are often used as an initial imaging technique, especially to detect larger stones in the kidneys or urinary tract. While X-rays are effective for identifying certain types of kidney stones, they may not detect smaller stones or stones located in the ureters. Despite this limitation, they remain widely used due to their affordability and ability to provide quick results.

The "Others" category accounts for about 5% of the kidney stone diagnostic market. This includes emerging technologies and alternative diagnostic methods such as magnetic resonance imaging (MRI), which is sometimes used to diagnose kidney stones. These methods are typically used in more specialized cases or when traditional imaging techniques are insufficient. The growth of the "Others" segment is driven by the development of new diagnostic tools aimed at improving accuracy and reducing invasiveness.

Global Kidney Stone Market, Segmentation by Geography

In this report, the Global Kidney Stone Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Global Kidney Stone Market Share (%), by Geographical Region, 2024

North America holds a significant share of the global kidney stone market, accounting for around 30% of the total market. The region benefits from advanced healthcare infrastructure, high awareness of kidney stone treatments, and a large number of healthcare facilities. The growing prevalence of kidney stones, driven by dietary habits and high obesity rates, has led to a steady demand for both diagnostic and treatment options. This trend is expected to continue, contributing to market growth in North America.

Europe represents approximately 25% of the global kidney stone market. The region is characterized by a well-established healthcare system and increasing patient awareness of kidney stone prevention and treatment. European countries with high healthcare standards and access to the latest medical technology are likely to see increased adoption of advanced treatments and diagnostic methods. The rising incidence of kidney stones due to lifestyle factors is anticipated to fuel further market expansion in Europe.

The Asia Pacific region is one of the fastest-growing segments of the kidney stone market, contributing nearly 20% to the global market share. Factors such as population growth, urbanization, and changing dietary patterns are driving the rise in kidney stone cases. Additionally, improvements in healthcare access and rising disposable income in countries like India and China are likely to boost the demand for both preventative and curative kidney stone treatments, making this region a key focus for market players.

The Middle East and Africa account for around 10% of the global kidney stone market. The region's healthcare infrastructure is improving, with growing access to advanced treatments for kidney stones. However, the market share remains smaller compared to other regions due to limited awareness, healthcare access in certain areas, and economic factors. Despite these challenges, increasing government investments in healthcare and rising awareness of kidney health are expected to foster growth in the coming years.

Latin America contributes approximately 15% to the global kidney stone market. This region is seeing a gradual increase in the number of kidney stone cases, largely attributed to dietary changes and lifestyle factors. Additionally, improving healthcare access and growing medical tourism in countries like Mexico and Brazil are likely to boost the adoption of kidney stone treatments. The market is expected to expand as public and private healthcare systems continue to develop in the region.

This report provides an in depth analysis of various factors that impact the dynamics of Global Kidney Stone Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.

Drivers, Restraints and Opportunity Analysis

Drivers:

• Increasing Prevalence
• Technological Advancements

• Growing Awareness - Growing awareness about kidney stone disease is emerging as a significant driver in the global kidney stone market. With increased education and outreach efforts, individuals are becoming more cognizant of the risk factors, symptoms, and preventive measures associated with kidney stones. Public health campaigns, healthcare provider initiatives, and online resources play a pivotal role in disseminating information and empowering patients to take proactive steps in managing their kidney health.

  This heightened awareness is fostering a shift towards early detection and intervention, leading to improved clinical outcomes and reduced morbidity associated with kidney stone disease. Individuals are increasingly seeking medical attention at the onset of symptoms, facilitating prompt diagnosis and treatment initiation. Moreover, as patients become more informed about lifestyle modifications and dietary changes that can mitigate stone formation, there is a growing emphasis on preventive strategies aimed at reducing the incidence of kidney stones and minimizing disease burden.

  Growing awareness is driving innovation in the kidney stone market, spurring investment in research and development of novel diagnostic tools, therapeutic interventions, and patient-centered care models. Healthcare providers are leveraging digital health platforms, telemedicine services, and mobile applications to engage with patients, deliver personalized education, and promote adherence to treatment regimens. By harnessing the power of technology and leveraging consumer awareness, stakeholders in the kidney stone market are poised to address unmet needs, enhance patient outcomes, and drive sustainable growth in the years to come.

Restraints:

• High Treatment Costs
• Lack of Access to Healthcare

• Side Effects of Treatment - While treatments for kidney stones are effective in managing the condition, they can sometimes be accompanied by side effects that warrant consideration in the global kidney stone market. Various interventions, such as medications, lithotripsy, ureteroscopy, and percutaneous nephrolithotomy, may entail adverse effects that impact patient well-being and treatment outcomes. Understanding and mitigating these side effects are essential for optimizing patient care and ensuring treatment adherence.

  Medications used to manage kidney stones may cause side effects ranging from mild discomfort to more serious complications. Common adverse reactions include gastrointestinal disturbances, such as nausea, vomiting, and diarrhea, which can affect treatment compliance and patient quality of life. Additionally, certain medications, such as potassium citrate or thiazide diuretics, may alter electrolyte levels, leading to electrolyte imbalances or metabolic abnormalities that require monitoring and management by healthcare providers.

  Invasive procedures, such as lithotripsy, ureteroscopy, and percutaneous nephrolithotomy, carry inherent risks of procedural complications and post-operative side effects. Patients undergoing these interventions may experience pain, discomfort, or urinary symptoms in the immediate post-procedural period, necessitating adequate pain management and supportive care. Furthermore, rare but serious complications, such as infection, bleeding, or injury to surrounding structures, may occur, highlighting the importance of meticulous surgical technique and vigilant post-operative monitoring to mitigate adverse outcomes.

  Despite the potential for side effects, the benefits of treatment often outweigh the risks in managing kidney stone disease. Healthcare providers play a crucial role in assessing patient risk factors, discussing potential side effects, and implementing strategies to minimize adverse reactions. Patient education, informed consent, and shared decision-making empower individuals to make informed choices about their treatment options, fostering a collaborative approach to kidney stone management that prioritizes patient safety, comfort, and overall well-being. By addressing side effects proactively and tailoring treatment plans to individual patient needs, stakeholders in the global kidney stone market can optimize therapeutic outcomes and enhance the patient experience.

Opportunities:

• Emerging Markets
• Personalized Medicine

• Preventive Strategies - Preventive strategies are increasingly recognized as essential components of kidney stone management in the global market. These strategies aim to reduce the incidence and recurrence of kidney stones by addressing modifiable risk factors, promoting lifestyle modifications, and implementing targeted interventions tailored to individual patient profiles. By adopting a proactive approach to kidney stone prevention, healthcare providers can mitigate disease burden, improve patient outcomes, and reduce healthcare costs associated with stone-related complications.

  In addition to dietary and hydration interventions, pharmacological therapy may be prescribed to prevent stone recurrence in high-risk individuals. Medications such as thiazide diuretics, potassium citrate, and allopurinol may be used to modify urinary chemistry, inhibit stone formation, or dissolve certain types of stones. Tailoring preventive strategies to individual patient characteristics, including stone composition, metabolic abnormalities, and underlying medical conditions, is crucial for optimizing treatment efficacy and reducing the risk of stone recurrence.

  By implementing comprehensive preventive strategies that encompass dietary modifications, hydration optimization, and pharmacological interventions, healthcare providers can empower patients to take an active role in managing their kidney stone risk. Education, counseling, and regular follow-up are essential components of preventive care, enabling patients to make informed lifestyle choices and adhere to personalized treatment plans. By prioritizing preventive measures in kidney stone management, stakeholders in the global market can mitigate disease burden, improve patient outcomes, and promote long-term kidney health.