Global Diabetic Gastroparesis Treatment Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Product Type;
Drugs - Gastroprokinetic Agents, Antiemetic Agents and Botulinum Toxin, Surgical Treatment Products - Gastric Electrical Stimulation (GES) Device, Percutaneous Endoscopic Gastrostomy (PEG) Kit and Parenteral Nutrition.By Distribution Channel;
Hospital Pharmacies, Retail Pharmacies and Online Pharmacies.By Disease Indication;
Compensated Gastroparesis and Gastric Failure.By Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Diabetic Gastroparesis Treatment Market (USD Million), 2021 - 2031
In the year 2024, the Global Diabetic Gastroparesis Treatment Market was valued at USD 4,063.25 million. The size of this market is expected to increase to USD 5,660.48 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 4.9%.
Global Diabetic Gastroparesis Treatment Market Growth, Share, Size, Trends and Forecast
*Market size in USD million
CAGR 4.9 %
Study Period | 2025 - 2031 |
---|---|
Base Year | 2024 |
CAGR (%) | 4.9 % |
Market Size (2024) | USD 4,063.25 Million |
Market Size (2031) | USD 5,660.48 Million |
Market Concentration | High |
Report Pages | 342 |
Major Players
- Allergan, plc
- Vanda Pharmaceuticals, Inc.
- Kimberly-Clark Corporation
- Boston Scientific Corporation
- Rhythm Pharmaceuticals, Inc.
- C. R. Bard, Inc. (Becton, Dickinson and Company)
- Medtronic Plc
- Abbott Laboratories
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Global Diabetic Gastroparesis Treatment Market
Fragmented - Highly competitive market without dominant players
The Global Diabetic Gastroparesis Treatment Market is experiencing consistent growth due to the rising incidence of diabetes and its associated gastrointestinal complications. Diabetic gastroparesis is a chronic disorder marked by delayed stomach emptying, which leads to symptoms such as nausea, bloating, and abdominal discomfort. The continuous increase in the diabetic population, particularly among individuals with long-standing Type 1 and Type 2 diabetes, is a key factor driving market demand.
Rising Demand for Prokinetic Agents
Prokinetic drugs continue to dominate treatment options, primarily because of their effectiveness in improving gastric motility. These medications currently represent over 40% of all therapeutic approaches for managing diabetic gastroparesis. Despite their widespread use, concerns about long-term side effects have encouraged the development of safer alternatives, leading to a surge in R&D efforts.
Non-Pharmacological Interventions Gaining Traction
In recent years, there has been a noticeable shift towards non-drug-based interventions, such as gastric electrical stimulation, nutritional therapy, and lifestyle adjustments. These alternative treatments are increasingly favored by patients who do not respond well to medications, accounting for nearly 25% of those seeking non-traditional solutions. This trend is contributing to a more diversified treatment landscape.
Future Outlook and Innovation
The future of the diabetic gastroparesis treatment market is expected to be shaped by continued innovation, with numerous therapies under development focusing on enhancing gastric function while minimizing adverse effects. Patient awareness and physician education are also increasing, which is likely to support the adoption of newer solutions and drive a projected annual growth rate exceeding 6%.
Global Diabetic Gastroparesis Treatment Market Recent Developments
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In July 2020, the U.S. Food and Drug Administration (FDA) granted approval for the use of tradipitant, developed by Vanda Pharmaceuticals, a U.S.-based biopharmaceutical firm. This decision enables patients to receive up to six months of treatment under expanded access provisions, with the possibility of renewal upon request. The approval specifically targets individuals managing gastroparesis, offering a new therapeutic avenue for those in need of extended treatment options.
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In July 15, 2020, Evoke Pharma, a U.S.-based pharmaceutical company, began the commercial production of Gimoti, following its approval by the U.S. Food and Drug Administration (FDA) in June 2020. Gimoti is a novel nasal spray formulation developed specifically for the treatment of diabetic gastroparesis, a diabetes-related complication that delays gastric emptying and affects digestion.The manufacturing was initiated in partnership with Patheon, a U.S.-based commercial manufacturing organization. This strategic collaboration set the stage for an anticipated product launch by the fourth quarter of 2020, aiming to address a significant unmet need in the gastroparesis treatment landscape.
Segment Analysis
In this report, the Global Diabetic Gastroparesis Treatment Market has been segmented by Product Type, Distribution Channel, Disease Indication and Geography.
Global Diabetic Gastroparesis Treatment Market, Segmentation by Product Type
The Global Diabetic Gastroparesis Treatment Market has been segmented by Product Type into Drugs - Gastroprokinetic Agents, Antiemetic Agents and Botulinum Toxin, Surgical Treatment Products - Gastric Electrical Stimulation (GES) Device, Percutaneous Endoscopic Gastrostomy (PEG) Kit and Parenteral Nutrition.
Gastroprokinetic Agents
Gastroprokinetic medications are often the first step in treating diabetic gastroparesis. These drugs help activate the stomach muscles, improving the passage of food through the digestive tract. Common options include metoclopramide and erythromycin. Clinical reports show that 30–40% of patients experience a reduction in symptoms when using these agents consistently.
Antiemetic Agents
To combat the frequent nausea and vomiting caused by delayed stomach emptying, antiemetic drugs are commonly prescribed. Medications like ondansetron and prochlorperazine help improve patient comfort. Research indicates that about 60% of patients find relief with regular antiemetic treatment.
Botulinum Toxin Injections
Botulinum toxin injections target the pyloric sphincter, a muscular valve between the stomach and small intestine. By relaxing this muscle, these injections can ease food movement and relieve symptoms. Although still considered experimental, studies report 50–60% effectiveness in short-term relief of gastroparesis symptoms.
Surgical and Advanced Procedural Treatments
Gastric Electrical Stimulation (GES)
GES devices provide electrical impulses to the stomach wall, helping regulate gastric contractions and enhance stomach emptying. This minimally invasive approach is particularly helpful for patients who don’t respond to medication. Up to 70% of GES users experience a notable reduction in nausea and vomiting.
Percutaneous Endoscopic Gastrostomy (PEG)
PEG tube placement offers a direct nutritional route into the stomach, bypassing dysfunctional gastric motility. It is typically used in severe cases where patients struggle to meet nutritional needs through oral intake. Approximately 15–20% of gastroparesis patients with severe symptoms benefit from PEG feeding.
Parenteral Nutrition
In cases where both oral and enteral feeding are inadequate, parenteral nutrition delivers essential nutrients intravenously. This method ensures patients receive adequate nutrition but is generally reserved for the most severe cases, making up 5–10% of diabetic gastroparesis treatment scenarios.
An Integrated Treatment Strategy
Managing diabetic gastroparesis requires a multifaceted treatment plan. Combining medication and procedural options allows for both symptom control and improved digestive function. These interventions not only relieve nausea, vomiting, and gastric stasis but also work toward improving long-term patient outcomes. With advancements in medical technology and growing research, treatment strategies are rapidly evolving—paving the way for more effective, personalized care for individuals living with this challenging condition.
Global Diabetic Gastroparesis Treatment Market, Segmentation by Distribution Channel
The Global Diabetic Gastroparesis Treatment Market has been segmented by Distribution Channel into Hospital Pharmacies, Retail Pharmacies and Online Pharmacies.
Hospital pharmacies dominate the global diabetic gastroparesis treatment market, serving as the primary distribution point for medications and medical devices. These pharmacies are crucial for managing inpatients and post-surgical patients, especially those requiring interventions like gastric electrical stimulation or botulinum toxin therapy. They contribute approximately 45–50% to the overall market share. Their integration within hospital settings allows for streamlined diagnosis, prescription, and dispensing, supporting continuity of care for critically affected patients.
Retail Pharmacies: Widely Accessible for Chronic Care
Retail pharmacies offer essential access to medications for patients managing diabetic gastroparesis outside of hospitals. Their broad geographic reach and availability of both prescription and over-the-counter treatments make them vital for long-term disease management. This segment accounts for nearly 30–35% of the distribution market. Retail pharmacists also play a supportive role in ensuring treatment adherence and addressing medication-related queries, especially for chronic disease sufferers.
Online Pharmacies: Emerging as a High-Growth Segment
Online pharmacies have rapidly expanded in response to growing digital health trends and consumer demand for convenience. Patients can now access medications like gastroprokinetic agents and antiemetics with a few clicks, including in underserved or rural regions. Currently capturing around 15–20% of the market, this channel is poised for significant expansion. Factors such as home delivery, discreet packaging, and availability of digital prescriptions continue to drive growth in this segment.
Diversified Distribution Enhances Market Reach
To address varied patient needs and improve access, healthcare companies are leveraging a multi-channel distribution strategy. This integrated approach—spanning hospital, retail, and online platforms—ensures a consistent supply of treatment options and supports patient-centric care. With technology and infrastructure evolving, the interplay of these channels is becoming a key driver of market penetration and sustained growth.
Global Diabetic Gastroparesis Treatment Market, Segmentation by Distribution Channel
The Global Diabetic Gastroparesis Treatment Market has been segmented by Disease Indication into Compensated Gastroparesis and Gastric Failure.
Compensated Gastroparesis: Mild but Manageable
In the early stages of diabetic gastroparesis, many patients experience a form known as compensated gastroparesis. Symptoms such as mild bloating, early satiety, and occasional nausea can often be managed with non-invasive treatments, including gastroprokinetic drugs, antiemetic agents, and dietary changes. Around 60–70% of patients in this category respond well to these measures, enabling them to lead relatively normal lives without requiring surgical intervention.
Gastric Failure: Severe Symptom Burden and Intervention Needs
Gastric failure represents the advanced form of diabetic gastroparesis, where symptoms become persistent and debilitating. This stage is marked by chronic vomiting, nutritional deficiencies, and a substantial decline in quality of life. Affecting up to 20% of patients, gastric failure typically necessitates aggressive treatment, including the use of Gastric Electrical Stimulation (GES) devices, PEG feeding tubes, and parenteral nutrition. These interventions help manage severe gastric dysfunction and prevent further complications.
Differentiated Treatment Improves Patient Outcomes
Recognizing the distinction between compensated gastroparesis and gastric failure is essential for tailoring effective treatment strategies. While early-stage management relies on medications and lifestyle changes, advanced cases benefit from a multidisciplinary care model. Studies show that early diagnosis and intervention in compensated cases may prevent progression to gastric failure in up to 40% of patients.
Market Implications of Disease Segmentation
This clinical segmentation has significant implications for the global diabetic gastroparesis treatment market. The rising prevalence of diabetes worldwide continues to drive demand for both pharmacological and procedural therapies. Treatment models that align with disease severity allow for more personalized care, improve clinical outcomes, and shape the development and adoption of innovative therapeutic solutions across the healthcare industry.
Global Diabetic Gastroparesis Treatment Market, Segmentation by Geography
In this report, the Global Diabetic Gastroparesis Treatment Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Diabetic Gastroparesis Treatment Market Share (%), by Geographical Region, 2024
Sure, let's break down the overview of the global diabetic gastroparesis treatment market by each geographical region:
North America: Market Leader in Gastroparesis Treatment
North America remains the leading region in the global diabetic gastroparesis treatment market, holding an estimated 35–40% share. This dominance stems from a combination of high diabetes prevalence, early diagnosis, and advanced medical infrastructure. The U.S. plays a key role with its widespread adoption of technologies like Gastric Electrical Stimulation (GES) and the availability of both pharmacological and surgical therapies. Strong research initiatives and patient awareness campaigns further bolster regional growth.
Europe: Technological Adoption and Expanding Access
Europe captures approximately 25–30% of the global market, driven by advancements in gastrointestinal treatment protocols and the presence of well-established healthcare systems. Countries like Germany, France, and the UK are at the forefront, with rising diagnosis rates for gastroparesis among diabetic populations. The region also benefits from public reimbursement frameworks and ongoing investments in medical innovation.
Asia Pacific: Emerging as the Fastest-Growing Region
Asia Pacific is positioned as the fastest-growing region in the diabetic gastroparesis treatment space. With a current market share of 15–20%, the region's growth is fueled by the increasing incidence of diabetes, improving healthcare accessibility, and rising public awareness. Key markets such as India, China, and Japan are witnessing rapid urbanization and health infrastructure development, creating new opportunities for therapeutic expansion.
Middle East, Africa, and Latin America: Gradual Expansion in Emerging Markets
Collectively, the Middle East & Africa and Latin America represent 10–15% of the global market. While these regions are still developing in terms of diagnostic capacity and healthcare access, increased government spending, urban population growth, and broader disease awareness are setting the stage for future growth. Market players are gradually expanding their presence in these territories to capitalize on untapped potential.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Diabetic Gastroparesis Treatment Market. These factors include; Market Drivers, Restraints and Opportunities Analysis,
Comprehensive Market Impact Matrix
This matrix outlines how core market forces—Drivers, Restraints, and Opportunities—affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
---|---|---|---|---|---|
Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development |
Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers, Restraints and Opportunity Analysis
Drivers:
- Rising Global Diabetes Incidence
- Innovations in Gastroparesis Treatment Technologies
- Improved Awareness of Gastroparesis Symptoms
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Surge in Healthcare Spending on Diabetes - A significant opportunity emerging in the global diabetic gastroparesis treatment market is the increasing adoption of personalized therapeutic approaches. With advancements in medical science and a stronger focus on individualized care, treatment strategies are becoming more tailored to specific patient needs. Diabetic gastroparesis, being a complex and variable condition, responds differently in each patient, making personalized therapies more effective than standardized treatment protocols.
The move toward individualized treatment is driven by innovations in diagnostic tools, genetic profiling, and biomarker-based assessments. These technologies enable healthcare providers to better understand the unique characteristics of a patient’s condition and select therapies that align with their specific physiological and clinical profile. This leads to improved outcomes, reduced adverse effects, and higher treatment adherence, especially in cases where symptom severity and treatment response can vary significantly.
Pharmaceutical and biotech companies are capitalizing on this trend by investing in the development of advanced drug formulations and delivery systems designed for specific patient segments. From extended-release medications to combination therapies that target multiple symptoms simultaneously, the market is expanding to include more nuanced options. These innovations reflect a broader shift toward precision medicine, offering solutions that go beyond symptom relief to address the root causes of delayed gastric emptying in diabetic patients.
This evolution is also supported by a more informed patient population that is increasingly seeking treatment plans tailored to their personal health profiles. As awareness grows and the demand for individualized care rises, the diabetic gastroparesis treatment market is poised for substantial growth. Tailored therapeutic solutions are not only improving the quality of care but also creating new pathways for innovation and long-term market expansion.
Restraints:
- Economic Barriers Impacting Treatment Adoption
- Elevated Costs of Gastroparesis Therapies
- Restricted Healthcare Access in Low-Income Areas
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Tough Regulatory Hurdles for New Approvals - One of the critical challenges restricting the expansion of the global diabetic gastroparesis treatment market is the presence of stringent regulatory barriers for new drug approvals. Due to the complex and often misunderstood nature of gastroparesis, regulatory authorities demand comprehensive clinical data that demonstrate both the safety and efficacy of any new treatment. This requirement significantly extends development timelines and increases the overall investment needed, posing a considerable hurdle for pharmaceutical companies.
The clinical evaluation of therapies targeting diabetic gastroparesis is especially difficult because the symptoms—such as nausea, bloating, and stomach discomfort—are often subjective and vary widely among patients. Regulatory bodies typically require long-duration studies that involve diverse patient groups to ensure consistent and reproducible results. These expectations contribute to frequent delays in product approval and deter smaller biotech firms from entering the market with innovative treatment options.
High failure rates in late-stage clinical trials further complicate the landscape. Many experimental drugs fail to meet the strict efficacy and safety benchmarks set by agencies like the FDA and EMA, particularly because of concerns about side effects linked to gastrointestinal motility agents. Some earlier treatments have shown unwanted effects on cardiac and neurological functions, leading to heightened caution during the review process. This has resulted in a conservative regulatory stance, limiting the flow of new therapies into the market.
Consequently, even the most promising drug candidates may face extended periods of additional research and scrutiny before becoming commercially available. These regulatory demands not only drive up development costs but also delay patient access to advanced care solutions. Unless regulatory frameworks evolve to accommodate novel approaches and faster review pathways, the growth of the diabetic gastroparesis treatment market will continue to face substantial resistance.
Opportunities:
- Expanding Elderly Demographic Drives Demand
- Breakthroughs in Treatment Technologies
- Market Growth Across Developing Economies
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Rise of Tailored Therapeutic Solutions - A significant opportunity emerging in the global diabetic gastroparesis treatment market is the increasing adoption of personalized therapeutic approaches. With advancements in medical science and a stronger focus on individualized care, treatment strategies are becoming more tailored to specific patient needs. Diabetic gastroparesis, being a complex and variable condition, responds differently in each patient, making personalized therapies more effective than standardized treatment protocols.
The move toward individualized treatment is driven by innovations in diagnostic tools, genetic profiling, and biomarker-based assessments. These technologies enable healthcare providers to better understand the unique characteristics of a patient’s condition and select therapies that align with their specific physiological and clinical profile. This leads to improved outcomes, reduced adverse effects, and higher treatment adherence, especially in cases where symptom severity and treatment response can vary significantly.
Pharmaceutical and biotech companies are capitalizing on this trend by investing in the development of advanced drug formulations and delivery systems designed for specific patient segments. From extended-release medications to combination therapies that target multiple symptoms simultaneously, the market is expanding to include more nuanced options. These innovations reflect a broader shift toward precision medicine, offering solutions that go beyond symptom relief to address the root causes of delayed gastric emptying in diabetic patients.
This evolution is also supported by a more informed patient population that is increasingly seeking treatment plans tailored to their personal health profiles. As awareness grows and the demand for individualized care rises, the diabetic gastroparesis treatment market is poised for substantial growth. Tailored therapeutic solutions are not only improving the quality of care but also creating new pathways for innovation and long-term market expansion.
Competitive Landscape Analysis
Key players in Global Diabetic Gastroparesis Treatment Market include;
- Janssen Global Services, LLC
- Cardinal Health, Inc.
- Evoke Pharma, Inc.
- Salix Pharmaceuticals, Inc.
- Alfa Wassermann SPA
- Abbott Laboratories
- Medtronic Plc.
- C. R. Bard, Inc.
- Rhythm Pharmaceuticals, Inc.
- Boston Scientific Corporation
- Kimberly-Clark Corporation
- Vanda Pharmaceuticals, Inc.
- Allergan, plc.
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product Type
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Disease Indication
- Market Snapshot, By Region
- Global Diabetic Gastroparesis Treatment Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Rising Global Diabetes Incidence
- Innovations in Gastroparesis Treatment Technologies
- Improved Awareness of Gastroparesis Symptoms
- Surge in Healthcare Spending on Diabetes
- Restraints
- Economic Barriers Impacting Treatment Adoption
- Elevated Costs of Gastroparesis Therapies
- Restricted Healthcare Access in Low-Income Areas
- Tough Regulatory Hurdles for New Approvals
- Opportunities
- Expanding Elderly Demographic Drives Demand
- Breakthroughs in Treatment Technologies
- Market Growth Across Developing Economies
- Rise of Tailored Therapeutic Solutions
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Diabetic Gastroparesis Treatment Market, By Product Type, 2021 - 2031 (USD Million)
- Drugs
- Gastroprokinetic Agents
- Antiemetic Agents
- Botulinum Toxin
- Surgical Treatment Products
- Gastric Electrical Stimulation (GES) Device
- Percutaneous Endoscopic Gastrostomy (PEG) Kit
- Parenteral Nutrition
- Drugs
- Global Diabetic Gastroparesis Treatment Market, By Distribution Channel, 2021 - 2031 (USD Million)
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
- Global Diabetic Gastroparesis Treatment Market, By Disease Indication, 2021 - 2031 (USD Million)
- Compensated Gastroparesis
- Gastric Failure
- Global Diabetic Gastroparesis Treatment Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Diabetic Gastroparesis Treatment Market, By Product Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Janssen Global Services, LLC
- Cardinal Health, Inc.
- Evoke Pharma, Inc.
- Salix Pharmaceuticals, Inc.
- Alfa Wassermann SPA
- Abbott Laboratories
- Medtronic Plc.
- C. R. Bard, Inc.
- Rhythm Pharmaceuticals, Inc.
- Boston Scientific Corporation
- Kimberly-Clark Corporation
- Vanda Pharmaceuticals, Inc.
- Allergan, plc.
- Company Profiles
- Analyst Views
- Future Outlook of the Market