Global Complex Regional Pain Syndrome Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

By Therapy Type;

Physical Therapy, Drugs, Analgesics, Antidepressants, Corticosteroids, and Others.

By Route of Administration;

Oral and Intravenous.

By Distribution Channel;

Hospital Pharmacy, Drug Stores, Retail Pharmacy, and E-commerce.

By Geography;

North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).
Report ID: Rn447706645 Published Date: February, 2025 Updated Date: March, 2025

Introduction

Global Complex Regional Pain Syndrome Market (USD Million), 2021 - 2031

In the year 2024, the Global Complex Regional Pain Syndrome Market was valued at USD 112.00 million. The size of this market is expected to increase to USD 131.41 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 2.3%.

CRPS, characterized by persistent pain typically affecting one arm or leg, often manifests following an injury, surgery, stroke, or heart attack. Several factors contribute to market growth, including heightened awareness and diagnosis of the condition, an aging population, increased focus on pain management, and ongoing research endeavors aimed at developing more effective treatments.

The COVID-19 pandemic adversely impacted the CRPS market. Disruptions in healthcare services, such as postponed treatments and interventions, led to delayed care and exacerbated suffering for some individuals. Additionally, pandemic-induced stress and isolation exacerbated mental health issues for CRPS patients. While telemedicine offered improved access to care, it could not fully replace in-person evaluations crucial for CRPS diagnosis and management. Lockdowns and restrictions on rehabilitation and physical therapy left some patients physically debilitated and in more pain. Economic uncertainties also hindered access to healthcare services, delaying research and clinical trials for new treatments, potentially limiting treatment options.

Looking ahead, key factors driving CRPS market growth include the rising incidence of CRPS and the increasing prevalence of chronic pain. CRPS is more prevalent in women, occurring about 3 to 4 times more frequently in females than males. While rare in children and adolescents, CRPS typically emerges in early adolescence, with most cases appearing between 7 and 9 years of age. In adults, onset age varies widely, ranging from 37 to 70 years. Predominantly affecting individuals of European descent, CRPS accounts for approximately 66% to 80% of cases. In the U.S. alone, CRPS affects nearly 200,000 patients annually, with an estimated diagnosis rate of approximately 5.46 individuals per 100,000 annually. The increasing incidence of CRPS and the growing prevalence of chronic pain underscore the drivers for future CRPS market growth.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Therapy Type
    2. Market Snapshot, By Route of Administration
    3. Market Snapshot, By Distribution Channel
    4. Market Snapshot, By Region
  4. Global Complex Regional Pain Syndrome Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Advancements in Treatment Options
        2. Growing Geriatric Population
        3. Increasing Healthcare Expenditure
        4. Technological Innovations
        5. Focus on Multimodal Pain Management
      2. Restraints
        1. Limited Understanding and Diagnosis
        2. Lack of Standardized Treatment Guidelines
        3. High Cost of Treatment
        4. Limited Efficacy of Current Therapies
      3. Opportunities
        1. Increasing Awareness and Diagnosis
        2. Advancements in Treatment Modalities
        3. Rising Healthcare Expenditure
        4. Focus on Personalized Medicine
        5. Patient-Centric Care Models
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry

  5. Market Segmentation
    1. Global Complex Regional Pain Syndrome Market, By Therapy Type, 2021 - 2031 (USD Million)
      1. Physical Therapy
      2. Drugs, Analgesics
      3. Antidepressants
      4. Corticosteroids
      5. Others
    2. Global Complex Regional Pain Syndrome Market, By Route of Administration, 2021 - 2031 (USD Million)
      1. Oral
      2. Intravenous
    3. Global Complex Regional Pain Syndrome Market, By Distribution Channel, 2021 - 2031 (USD Million)
      1. Hospital Pharmacy
      2. Drug Stores
      3. Retail Pharmacy
      4. E-commerce
    4. Global Complex Regional Pain Syndrome Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Nordic
        5. Benelux
        6. Italy
        7. Spain
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Boston Scientific Corporation
      2. Medtronic
      3. GlaxoSmithKline plc
      4. Johnson & Johnson
      5. Mylan N.V
      6. Abiogen Pharma SpA
      7. Axsome Therapeutics
      8. Grunenthal GmbH
      9. Mallinckrodt Plc
  7. Analyst Views
  8. Future Outlook of the Market