CDNA Synthesis Market

By Type;

Oligonucleotide Synthesis and Gene Synthesis

By Product Type;

Kits, Cloning & Mutagenesis, PCR, Sequencing, Enzymes, Ligases, Phosphatases, Polymerases, Restriction Endonucleases, and Others

By Application;

Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing, and Others

By End User;

Research Centers, Academic Institutes, Hospitals & Pharmaceutical, and Biotechnology Companies

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn197177498 Published Date: August, 2025

CDNA Synthesis Market Overview

CDNA Synthesis Market (USD Million)

CDNA Synthesis Market was valued at USD 83.57 million in the year 2024. The size of this market is expected to increase to USD 176.48 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 11.3%.


CDNA Synthesis Market

*Market size in USD million

CAGR 11.3 %


Study Period2025 - 2031
Base Year2024
CAGR (%)11.3 %
Market Size (2024)USD 83.57 Million
Market Size (2031)USD 176.48 Million
Market ConcentrationLow
Report Pages349
83.57
2024
176.48
2031

Major Players

  • Sigma-Aldrich Co. LLC.
  • QIAGEN
  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • TATAA Biocenter
  • Bioline
  • New England Biolabs

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

CDNA Synthesis Market

Fragmented - Highly competitive market without dominant players


The CDNA Synthesis Market is witnessing significant growth due to the increasing focus on gene expression profiling across various biomedical research fields. With over 60% of molecular biology workflows now integrating cDNA synthesis for downstream applications like RT-PCR and qPCR, the need for reliable and high-yield synthesis kits is expanding. This trend is further strengthened by the rising adoption of transcriptomics in disease diagnostics and drug development.

Technological Advancements Fueling Innovation
Rapid innovations in reverse transcriptase enzymes and improved buffer systems have boosted efficiency and fidelity in cDNA synthesis. New enzyme formulations have improved sensitivity by over 40%, allowing researchers to work with minimal RNA input and degraded samples. These advancements are helping laboratories generate high-quality complementary DNA even from challenging or low-yield RNA specimens, expanding the scope of use.

Surge in Clinical and Diagnostic Applications
The integration of cDNA synthesis into diagnostic workflows is accelerating, with nearly 45% of diagnostic laboratories employing it for RNA virus detection and oncogene expression analysis. Its pivotal role in molecular diagnostics—particularly in infectious diseases and cancer—is elevating its clinical relevance. Increased reliance on RNA-based biomarkers is translating into higher demand for robust cDNA synthesis protocols.

Expansion of Academic and Research Funding
Rising investments in genomics and molecular biology research by academic and government bodies have contributed to a 35% increase in the use of cDNA synthesis tools in academic institutions. These tools are critical in transcriptome research, enabling insights into complex regulatory mechanisms and disease pathogenesis. As global focus on biotechnology intensifies, the research applications of cDNA synthesis are poised to expand rapidly.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Type
    2. Market Snapshot, By Product Type
    3. Market Snapshot, By Application
    4. Market Snapshot, By End User
    5. Market Snapshot, By Region
  4. Global CDNA Synthesis Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Growing demand for gene therapy
        2. Advancements in biotechnology
        3. Increasing research activities
        4. Rising prevalence of genetic disorders
        5. Technological innovations in genomics
      2. Restraints
        1. Ethical concerns and regulations
        2. High cost of technology
        3. Limited awareness in some regions
        4. Complexity of gene editing
        5. Potential safety issues
      3. Opportunities
        1. Expanding applications in healthcare
        2. Collaborations for research
        3. Emerging markets adoption
        4. Personalized medicine trends
        5. Development of CRISPR technology
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Global CDNA Synthesis Market, By Type, 2021 - 2031 (USD Million)
      1. Oligonucleotide Synthesis
      2. Gene Synthesis.
    2. Global CDNA Synthesis Market, By Product Type, 2021 - 2031 (USD Million)
      1. Kits
      2. Cloning and Mutagenesis
      3. PCR
      4. Sequencing
      5. Others
      6. Enzymes
      7. Ligases
      8. Phosphatases
      9. Polymerases
      10. Restriction Endonucleases
      11. Others
    3. Global CDNA Synthesis Market, By Application, 2021 - 2031 (USD Million)
      1. Cloning
      2. Epigenetics
      3. PCR
      4. Restriction Digestion
      5. Sequencing
      6. Other
    4. Global CDNA Synthesis Market, By End User, 2021 - 2031 (USD Million)
      1. Research Centers
      2. Academic Institutes
      3. Hospitals
      4. Pharmaceutical and Biotechnology Companies
    5. Global CDNA Synthesis Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Sigma-Aldrich Co. LLC.
      2. QIAGEN
      3. Thermo Fisher Scientific Inc.
      4. Bio-Rad Laboratories, Inc.
      5. TATAA Biocenter
      6. Bioline
      7. New England Biolabs
  7. Analyst Views
  8. Future Outlook of the Market