Global Bone Cement & Glue Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Product Type;
Synthetic Bone Glue, and Natural Bone Glue.By Application;
Arthroplasty, Total Knee Arthroplasty, Total Hip Arthroplasty, Total Shoulder Arthroplasty, Kyphoplasty, and Vertebroplasty.By End User;
Hospitals, Ambulatory Surgery Centers (ASCs), and Clinics/Physician Offices.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Bone Cement & Glue Market (USD Million), 2021 - 2031
In the year 2024, the Global Bone Cement & Glue Market was valued at USD 1,208.80 million. The size of this market is expected to increase to USD 1,781.88 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 5.7%.
The global bone cement and glue market has witnessed significant growth in recent years, driven by advancements in orthopedic surgeries and an increasing aging population worldwide. Bone cement and glue play crucial roles in stabilizing and reinforcing orthopedic implants during procedures such as joint replacement surgeries and spinal surgeries. This market encompasses a variety of products designed to meet the diverse needs of surgeons and patients, ranging from traditional polymethyl methacrylate (PMMA) bone cement to newer formulations and adhesives.
One of the primary drivers of market growth is the rising prevalence of musculoskeletal disorders and osteoarthritis, particularly among the elderly population. As people live longer and remain active later in life, the demand for effective orthopedic treatments that enhance mobility and reduce pain has surged. Bone cement and glue offer reliable solutions to secure implants and provide immediate structural support, thereby improving patient outcomes and recovery times.
Technological advancements in biomaterials and adhesive techniques have expanded the capabilities of bone cement and glue. Innovations such as antibiotic-loaded cement for infection prevention, biocompatible formulations for reduced allergic reactions, and adhesive agents that promote bone growth have broadened the applications of these products across diverse orthopedic specialties.
The market landscape is also influenced by the increasing adoption of minimally invasive surgical techniques, which require specialized bone cement and glue formulations that can be delivered through smaller incisions with precision. This trend not only enhances patient comfort and accelerates recovery but also drives the demand for innovative adhesive solutions that ensure strong, durable fixation of implants.
The global bone cement and glue market is poised for continued growth as healthcare providers and patients alike seek advanced orthopedic solutions that improve surgical outcomes and quality of life. With ongoing research and development efforts aimed at enhancing product efficacy and safety, the market is likely to witness further evolution and innovation in the coming years.
Global Bone Cement & Glue Market Recent Developments
- In 2021, The company Smith & Nephew (UK) acquired the Extremity Orthopedics business of Integra LifeSciences to expand its shoulder, upper, and lower extremities product portfolio.
- In 2021, Zimmer Biomet (US) Completed the spinoff of spine and dental businesses into a new public company, ZimVie Inc. (“ZimVie”). The transaction was intended to benefit its stockholders by enhancing the focus of both Zimmer Biomet and ZimVie to meet the needs of patients and customers.
Segment Analysis
The global bone cement and glue market is segmented by product type into synthetic bone glue and natural bone glue. Synthetic bone glues dominate the market due to their superior properties, such as strength, durability, and the ability to be customized for specific surgical procedures. These synthetic adhesives are commonly used in joint replacement surgeries and other orthopedic procedures, offering excellent mechanical properties that enhance the stability and longevity of the implants. On the other hand, natural bone glues, derived from biological sources, are gaining attention for their biocompatibility and reduced risk of infection. These products are often preferred in certain medical applications where tissue integration and healing are prioritized.
In terms of application, the market is divided into several key categories, including arthroplasty, total knee arthroplasty (TKA), total hip arthroplasty (THA), total shoulder arthroplasty (TSA), kyphoplasty, and vertebroplasty. Arthroplasty, particularly TKA and THA, holds the largest share, as these procedures are commonly performed in aging populations with degenerative joint diseases. Kyphoplasty and vertebroplasty are increasingly popular due to their effectiveness in treating vertebral compression fractures caused by osteoporosis. The demand for bone cement and glue is expected to grow with the rise in joint replacement surgeries and spinal procedures, fueled by the aging demographic and the increasing prevalence of musculoskeletal disorders.
The market is also segmented by end-user, which includes hospitals, ambulatory surgery centers (ASCs), and clinics/physician offices. Hospitals account for the largest share of the market, owing to their advanced surgical infrastructure, higher patient volume, and availability of specialized orthopedic surgeons. ASCs are emerging as a significant end-user segment due to their cost-effectiveness and ability to perform a wide range of outpatient procedures. Clinics and physician offices, while smaller in size, are expanding as more non-invasive and minimally invasive procedures, including some forms of bone cement applications, are being offered in these settings, especially for less complex cases.
Geographically, the bone cement and glue market is divided into North America, Europe, Asia Pacific, the Middle East and Africa, and Latin America. North America holds the largest market share, driven by the high incidence of orthopedic surgeries and the presence of advanced healthcare infrastructure. Europe follows closely, with a significant demand for orthopedic products driven by an aging population and high healthcare standards. The Asia Pacific region is expected to witness the highest growth rate, due to increasing healthcare investments, a rising geriatric population, and improving medical infrastructure in countries like China and India. Latin America and the Middle East and Africa are also growing markets, supported by the increasing prevalence of joint diseases and advancements in healthcare facilities.
Global Bone Cement & Glue Segment Analysis
In this report, the Global Bone Cement & Glue Market has been segmented by Product Type, Application, End User and Geography.
Global Bone Cement & Glue Market, Segmentation by Product Type
The Global Bone Cement & Glue Market has been segmented by Product Type into Synthetic Bone Glue, and Natural Bone Glue.
The global bone cement and glue market is primarily segmented based on product type into synthetic bone glue and natural bone glue. Synthetic bone glue has gained significant traction due to its ability to mimic the properties of natural bone, providing a strong and durable bond. It is widely used in various orthopedic procedures, such as joint replacement surgeries, where stability and longevity are essential. The popularity of synthetic bone glue is attributed to its higher adaptability, ease of use, and effective performance in clinical applications.
On the other hand, natural bone glue is derived from biological materials, offering advantages like biocompatibility and natural healing properties. It is primarily used in situations where the body’s own tissues are involved in the healing process. Natural bone glue has seen increasing demand in regenerative medicine, where there is a push for more organic and less synthetic materials to promote tissue regeneration and reduce the risk of complications.
Both synthetic and natural bone glues serve critical roles in the medical field, with their applications varying depending on the specific needs of the procedure and the patient's condition. While synthetic bone glue is often favored for its strength and versatility, natural bone glue is preferred in procedures requiring high biocompatibility and alignment with natural healing processes. The continued development of both types aims to improve surgical outcomes and patient recovery times, contributing to the overall growth of the global bone cement and glue market.
Global Bone Cement & Glue Market, Segmentation by Application
The Global Bone Cement & Glue Market has been segmented by Application into Arthroplasty, Total Knee Arthroplasty, Total Hip Arthroplasty, Total Shoulder Arthroplasty, Kyphoplasty and Vertebroplasty.
The global bone cement and glue market is segmented by application into several key areas, reflecting the diverse uses of these products in various orthopedic procedures. The primary segments include Arthroplasty, Total Knee Arthroplasty, Total Hip Arthroplasty, Total Shoulder Arthroplasty, Kyphoplasty, and Vertebroplasty. Each of these applications leverages bone cement and glue for the stabilization and fixation of implants, addressing specific clinical needs and enhancing surgical outcomes.Arthroplasty encompasses a broad category of joint replacement surgeries where bone cement and glue are used to secure prosthetic components, ensuring joint stability and longevity. This segment is driven by the increasing incidence of joint disorders and the growing aging population.
Total Knee Arthroplasty involves the replacement of the knee joint, a procedure that relies heavily on bone cement to achieve optimal fixation and load distribution. The high prevalence of knee osteoarthritis and advancements in surgical techniques contribute to the demand in this segment.Total Hip Arthroplasty focuses on hip joint replacement, where bone cement plays a critical role in anchoring the femoral and acetabular components. The rising number of hip fractures and degenerative hip conditions among the elderly population drives this segment's growth.
Total Shoulder Arthroplasty addresses shoulder joint replacements, utilizing bone cement and glue to stabilize the implant and restore shoulder function. This segment benefits from increasing awareness of shoulder arthroplasty as a treatment for severe arthritis and rotator cuff injuries.Kyphoplasty and Vertebroplasty are minimally invasive procedures used to treat vertebral compression fractures. These techniques involve the injection of bone cement into the collapsed vertebrae to restore stability and alleviate pain. The growing prevalence of osteoporosis and related spinal fractures significantly boosts the demand in these segments.Overall, the segmentation of the bone cement and glue market by application highlights the critical role these materials play in a variety of orthopedic surgeries, catering to specific clinical requirements and improving patient outcomes across different anatomical sites.
Global Bone Cement & Glue Market, Segmentation by End User
The Global Bone Cement & Glue Market has been segmented by End User into Hospitals, Ambulatory Surgery Centers (ASCs); and Clinics/Physician Offices.
Hospitals are the primary end users of bone cement and glue, accounting for the largest share of the market. Hospitals perform a wide range of orthopedic procedures, including complex joint replacements and spinal surgeries, which require reliable and effective bone cement and glue products. The availability of advanced surgical facilities, experienced healthcare professionals, and comprehensive post-operative care makes hospitals a critical segment for the adoption and utilization of these materials. The increasing prevalence of musculoskeletal disorders and the growing number of elderly patients undergoing joint replacement surgeries further drive the demand in this segment.
Ambulatory Surgery Centers (ASCs) represent a rapidly growing segment within the bone cement and glue market. ASCs offer a cost-effective and convenient alternative to traditional hospital settings for performing orthopedic surgeries. These centers are equipped to handle minimally invasive procedures such as arthroplasty, kyphoplasty, and vertebroplasty, which often utilize bone cement and glue for implant fixation and vertebral stabilization. The rise in outpatient surgeries, driven by advancements in surgical techniques and anesthesia, along with the emphasis on reducing healthcare costs and improving patient convenience, contributes to the expansion of the ASC segment.
Clinics/Physician Offices also play a significant role in the bone cement and glue market, particularly in the context of minor orthopedic procedures and follow-up care. Clinics and physician offices often serve as the first point of contact for patients with musculoskeletal issues, providing diagnosis, treatment planning, and sometimes minor surgical interventions. The use of bone cement and glue in these settings is typically associated with less complex procedures and pain management interventions. The accessibility and personalized care offered by clinics and physician offices make them an important segment for the distribution and application of bone cement and glue products.
The segmentation of the global bone cement and glue market by end user highlights the diverse settings in which these products are utilized, each with unique demands and contributions to market growth. Hospitals dominate the market due to their capacity for complex surgeries, while ASCs and clinics/physician offices represent growing segments driven by cost-efficiency, convenience, and accessibility. This segmentation underscores the importance of tailoring bone cement and glue products to meet the specific needs of different healthcare environments.
Global Bone Cement & Glue Market, Segmentation by Geography
In this report, the Global Bone Cement & Glue Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Bone Cement & Glue Market Share (%), by Geographical Region, 2024
The global bone cement and glue market share by geographical region reveals distinct trends and dominant regions that contribute significantly to market growth. As of the previous year, North America held the largest share of the market, accounting for approximately 35%. This dominance is attributed to the region's advanced healthcare infrastructure, high prevalence of orthopedic conditions such as osteoarthritis and osteoporosis, and the strong presence of leading market players. Additionally, the adoption of advanced surgical techniques and the high rate of joint replacement surgeries in the United States and Canada further bolster the market share in this region.
Europe followed closely, capturing around 30% of the global market share. The region's robust healthcare system, coupled with a significant elderly population, drives the demand for bone cement and glue. Countries like Germany, the UK, and France are key contributors due to their high incidence of orthopedic procedures and well-established healthcare facilities. The presence of renowned research institutions and ongoing advancements in orthopedic surgery techniques also play a crucial role in maintaining Europe's substantial market share.
The Asia Pacific region demonstrated a remarkable growth trajectory, holding approximately 20% of the market share. This growth is primarily driven by the increasing healthcare expenditure, improving healthcare infrastructure, and rising awareness about advanced orthopedic treatments in emerging economies such as China, India, and Japan. The region's large and aging population, coupled with a growing number of orthopedic surgeries, fuels the demand for bone cement and glue products. Government initiatives to enhance healthcare access and the expansion of medical tourism further contribute to the market's expansion in Asia Pacific.
Latin America and the Middle East & Africa collectively accounted for the remaining 15% of the global market share. In Latin America, countries like Brazil and Mexico are experiencing a rise in orthopedic procedures due to improving healthcare services and increasing awareness about joint replacement surgeries. The Middle East & Africa region, while still developing in terms of healthcare infrastructure, shows potential for growth driven by investments in healthcare facilities and a growing focus on advanced medical treatments. However, economic constraints and limited access to healthcare in some parts of these regions pose challenges to market growth.
The geographical distribution of the global bone cement and glue market highlights the leading roles of North America and Europe, driven by advanced healthcare systems and high procedural volumes. Meanwhile, the Asia Pacific region is emerging as a significant growth area due to improving healthcare infrastructure and rising surgical demand. Latin America and the Middle East & Africa, though smaller in market share, present opportunities for future growth with ongoing healthcare developments.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Bone Cement & Glue Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers:
- Aging population
- Increasing prevalence of musculoskeletal disorders
- Technological advancements in biomaterials
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Rising demand for minimally invasive surgeries - The rising demand for minimally invasive surgeries (MIS) has been a significant driver in the global bone cement and glue market, revolutionizing orthopedic procedures and patient outcomes. MIS techniques involve smaller incisions compared to traditional open surgeries, resulting in reduced trauma to surrounding tissues, less post-operative pain, shorter hospital stays, and quicker recovery times for patients. These advantages have led to a growing preference among both patients and surgeons, thereby fueling the demand for specialized bone cement and glue solutions that cater to the unique requirements of MIS.
Orthopedic surgeries such as joint replacements (e.g., hip and knee) and spinal procedures (e.g., vertebroplasty and kyphoplasty) benefit greatly from MIS approaches, which rely heavily on effective fixation and stabilization of implants using bone cement and glue. Manufacturers have responded to this trend by developing advanced formulations that ensure optimal bonding strength, ease of application through small incisions, and compatibility with MIS instruments.
The shift towards minimally invasive techniques is supported by ongoing advancements in surgical tools, imaging technologies (such as fluoroscopy and navigation systems), and robotic-assisted surgery. These innovations enhance surgical precision, improve outcomes, and expand the scope of MIS across various orthopedic specialties.
From a market perspective, the rising demand for MIS has created opportunities for growth and innovation in the bone cement and glue sector. Companies are increasingly focusing on developing new products that meet the specific needs of minimally invasive procedures, including formulations with enhanced viscosity, setting times, and biocompatibility. This market trend is expected to continue driving advancements in orthopedic surgery techniques and contributing to the overall expansion of the bone cement and glue market globally.
Restraints:
- High cost of advanced bone cement and glue products
- Regulatory challenges and product approval processes
- Complications associated with cemented implants
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Limited reimbursement policies in certain regions - Limited reimbursement policies in certain regions pose a significant restraint to the growth of the global bone cement and glue market. Reimbursement policies vary widely across countries and regions, influencing the affordability and accessibility of orthopedic procedures that require bone cement and glue products.
In some regions, reimbursement may not adequately cover the cost of advanced bone cement and glue technologies, which can be expensive due to their innovative formulations and materials. This disparity can discourage healthcare providers from adopting newer, more effective products in favor of more traditional and lower-cost options. As a result, patients may not have access to the latest advancements in orthopedic surgery, potentially impacting treatment The complex and often lengthy process of gaining reimbursement approval for new products can delay market entry and adoption, particularly for smaller manufacturers or companies introducing novel technologies. This regulatory hurdle requires extensive clinical evidence demonstrating the safety, efficacy, and cost-effectiveness of bone cement and glue products, which can be resource-intensive and time-consuming.
Variations in reimbursement policies can create disparities in healthcare delivery and patient care outcomes between regions with differing financial resources and healthcare priorities. This situation underscores the need for greater alignment and standardization of reimbursement policies across regions to promote equitable access to advanced orthopedic treatments worldwide.
Addressing the challenge of limited reimbursement policies requires collaboration among healthcare providers, policymakers, and industry stakeholders to advocate for fair reimbursement practices that support innovation, improve patient outcomes, and ensure sustainable growth of the bone cement and glue market globally.
Opportunities:
- Development of antibiotic-loaded bone cement
- Expansion into emerging markets
- Growing adoption of biocompatible and bioresorbable materials
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Integration of 3D printing technology in product manufacturing - The integration of 3D printing technology in the manufacturing of bone cement and glue products represents a transformative advancement in the orthopedic industry. 3D printing, also known as additive manufacturing, allows for the precise fabrication of customized implants and medical devices, tailored to the specific anatomical requirements of individual patients. This level of customization enhances the fit and function of orthopedic implants, leading to improved surgical outcomes and patient satisfaction.
One of the primary advantages of 3D printing in the production of bone cement and glue products is the ability to create complex geometries and structures that are difficult or impossible to achieve with traditional manufacturing methods. This capability is particularly beneficial for developing porous implants that mimic the natural bone structure, promoting better integration and osseointegration. Additionally, 3D printing enables the incorporation of multiple materials within a single construct, allowing for the combination of bone cement with bioactive agents that can enhance healing and reduce the risk of infection.
The adoption of 3D printing technology also streamlines the production process, reducing lead times and costs associated with custom-made implants and surgical instruments. This efficiency is crucial in responding to the growing demand for personalized orthopedic solutions, driven by the increasing prevalence of musculoskeletal disorders and the aging population. Moreover, the ability to rapidly prototype and test new designs accelerates innovation and the introduction of novel products to the market.
Competitive Landscape Analysis
Key players in Global Bone Cement & Glue Market include:
- Stryker
- Zimmer Biomet
- Depuy Synthes
- Smith & Nephew
- Arthrex
- DJO Global
- Exactech
- Teknimed
- Heraeus Medical
- Cryolife
- Cardinal Health
- Trimph
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product Type
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Global Bone Cement & Glue Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Aging population
- Increasing prevalence of musculoskeletal disorders
- Technological advancements in biomaterials
- Rising demand for minimally invasive surgeries
- Restraints
- High cost of advanced bone cement and glue products
- Regulatory challenges and product approval processes
- Complications associated with cemented implants
- Limited reimbursement policies in certain regions
- Opportunities
- Development of antibiotic-loaded bone cement
- Expansion into emerging markets
- Growing adoption of biocompatible and bioresorbable materials
- Integration of 3D printing technology in product manufacturing
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Bone Cement & Glue Market, By Product Type, 2021 - 2031 (USD Million)
- Synthetic Bone Glue
- Natural Bone Glue
- Global Bone Cement & Glue Market, By Application, 2021 - 2031 (USD Million)
- Arthroplasty
- Total Knee Arthroplasty
- Total Hip Arthroplasty
- Total Shoulder Arthroplasty
- Kyphoplasty
- Vertebroplasty
- Global Bone Cement & Glue Market, By End User, 2021 - 2031 (USD Million)
- Hospitals
- Ambulatory Surgery Centers
- Clinics/Physician Offices
- Global Bone Cement & Glue Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Bone Cement & Glue Market, By Product Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Stryker
- Zimmer Biomet
- Depuy Synthes
- Smith & Nephew
- Arthrex
- DJO Global
- Exactech
- Teknimed
- Heraeus Medical
- Cryolife
- Cardinal Health
- Trimph
- Company Profiles
- Analyst Views
- Future Outlook of the Market