Bone Cement And Glue Market
By Product Type;
Synthetic Bone Glue and Natural Bone GlueBy Application;
Arthroplasty, Total Knee Arthroplasty, Total Hip Arthroplasty, Total Shoulder Arthroplasty, Kyphoplasty, and VertebroplastyBy End User;
Hospitals, Ambulatory Surgery Centers (ASCs), and Clinics/Physician OfficesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031).Bone Cement & Glue Market Overview
Bone Cement & Glue Market (USD Million)
Bone Cement & Glue Market was valued at USD 1,208.80 million in the year 2024. The size of this market is expected to increase to USD 1,781.88 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 5.7%.
Bone Cement And Glue Market
*Market size in USD million
CAGR 5.7 %
Study Period | 2025 - 2031 |
---|---|
Base Year | 2024 |
CAGR (%) | 5.7 % |
Market Size (2024) | USD 1,208.80 Million |
Market Size (2031) | USD 1,781.88 Million |
Market Concentration | Medium |
Report Pages | 302 |
Major Players
- Stryker
- Zimmer Biomet
- Depuy Synthes
- Smith & Nephew
- Arthrex
- DJO Global
- Exactech
- Teknimed
- Heraeus Medical
- Cryolife
- Cardinal Health
- Trimph
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Bone Cement And Glue Market
Fragmented - Highly competitive market without dominant players
The Bone Cement And Glue Market is witnessing steady growth, largely driven by the rising incidence of hormone-dependent conditions such as prostate cancer, endometriosis, and uterine fibroids. As a potent gonadotropin-releasing hormone (GnRH) agonist, leuprolide acetate plays a critical role in regulating hormone production, making it a preferred treatment in both oncology and reproductive health. Notably, prostate cancer therapies account for nearly 60% of leuprolide acetate's overall clinical use, underlining its vital role in modern medical protocols.
Increasing Preference for Hormone-Based Therapies
The market is also benefiting from the broader acceptance of hormone therapies due to their precision in treating specific conditions and delivering favorable outcomes. As patient and provider awareness increases, there is a growing shift toward therapies that offer targeted hormone suppression. Current data suggests that hormone therapy prescriptions now represent over 45% of treatments for reproductive health disorders, reflecting this trend toward more specialized pharmacological solutions.
Innovations in Drug Delivery Systems
Technological advancements in drug formulations are significantly shaping the future of this market. Long-acting injectable formats and depot systems have gained popularity for their convenience and improved adherence. In fact, nearly 35% of new drug innovations in this segment emphasize extended-release mechanisms, which help maintain therapeutic levels in the body while reducing the need for frequent dosing. These improvements are enhancing treatment efficacy and patient experience.
Supportive Healthcare Policies and Regulations
Governmental support and evolving healthcare policies are further stimulating market expansion. Investments in reproductive and cancer-related healthcare programs are making leuprolide acetate therapies more accessible and affordable. Presently, more than 40% of chronic disease management programs integrate hormone-based treatment approaches, highlighting the regulatory push toward comprehensive and inclusive care strategies.
Growth Trajectory and Market Potential
With its versatile applications and strong clinical reputation, the leuprolide acetate market is expected to grow steadily in the years ahead. Ongoing clinical research, increasing healthcare investments, and strategic industry collaborations are creating a fertile landscape for innovation.
Global Bone Cement & Glue Market Recent Developments
- In 2021, The company Smith & Nephew (UK) acquired the Extremity Orthopedics business of Integra LifeSciences to expand its shoulder, upper, and lower extremities product portfolio.
- In 2021, Zimmer Biomet (US) Completed the spinoff of spine and dental businesses into a new public company, ZimVie Inc. (“ZimVie”). The transaction was intended to benefit its stockholders by enhancing the focus of both Zimmer Biomet and ZimVie to meet the needs of patients and customers.
Bone Cement & Glue Market Segment Analysis
In this report, the Bone Cement & Glue Market has been segmented by Product Type, Application, End User and Geography.
Bone Cement & Glue Market, Segmentation by Product Type
The Bone Cement & Glue Market has been segmented by Product Type into Synthetic Bone Glue, and Natural Bone Glue.
Synthetic Bone Glue
Synthetic bone glue dominates the bone cement and glue market, capturing nearly 65% of the segment. Its popularity stems from its reliable bonding strength and adaptability in various medical procedures, particularly in orthopedics and dentistry. The synthetic composition offers enhanced control over properties such as setting time and durability, making it ideal for quick and effective bone repair.
Natural Bone Glue
Representing around 35% of the market, natural bone glue is prized for its natural origin and excellent biocompatibility with bone tissue. Extracted from animal collagen, it supports bone healing by promoting tissue integration. Despite its benefits, natural bone glue's market share is limited due to slower curing times and variability in performance compared to synthetic options.
Bone Cement & Glue Market, Segmentation by Application
The Bone Cement & Glue Market has been segmented by Application into Arthroplasty, Total Knee Arthroplasty, Total Hip Arthroplasty, Total Shoulder Arthroplasty, Kyphoplasty and Vertebroplasty.
Arthroplasty
Accounting for nearly 40% of the bone cement and glue market, arthroplasty is a key application involving joint reconstruction or replacement. Bone cement is essential in securing implants, providing stability, and improving overall surgical success in this segment.
Total Knee Arthroplasty
Making up approximately 25% of market applications, total knee arthroplasty is a widely performed procedure. Bone cement plays a vital role in ensuring the durable fixation of knee implants, which is critical for maintaining joint function and patient mobility post-surgery.
Total Hip Arthroplasty
With around 20% market share, total hip arthroplasty relies on bone cement for the secure anchoring of hip prostheses. This improves implant longevity and aids patient recovery from hip-related conditions.
Total Shoulder Arthroplasty
Contributing roughly 5% to the market, total shoulder arthroplasty uses bone cement to firmly attach prosthetic parts, enhancing shoulder movement and providing effective pain management.
Kyphoplasty
Representing about 5% of applications, kyphoplasty utilizes bone cement in minimally invasive treatment for vertebral compression fractures. This procedure restores spinal structure and alleviates pain by stabilizing damaged vertebrae.
Vertebroplasty
Similarly accounting for close to 5%, vertebroplasty involves injecting bone cement into fractured vertebrae to strengthen and stabilize the spine, promoting quicker pain relief and improved mobility.
Bone Cement & Glue Market, Segmentation by End User
The Bone Cement & Glue Market has been segmented by End User into Hospitals, Ambulatory Surgery Centers (ASCs); and Clinics/Physician Offices.
Hospitals
Making up around 70% of the bone cement and glue end-user market, hospitals remain the primary setting for the application of these products. Equipped with state-of-the-art surgical technology and specialized orthopedic teams, hospitals handle complex procedures such as joint replacements and spinal surgeries that require dependable bone cement solutions.
Ambulatory Surgery Centers (ASCs)
Representing nearly 20% of the market, Ambulatory Surgery Centers are increasingly favored for outpatient orthopedic surgeries. Their demand for bone cement products is rising due to the need for quick-setting and highly effective materials suitable for minimally invasive procedures.
Clinics/Physician Offices
Clinics and physician offices contribute approximately 10% to the bone cement and glue market. These facilities primarily focus on less complex orthopedic treatments and outpatient care, emphasizing patient convenience and affordability.
Bone Cement & Glue Market, Segmentation by Geography
In this report, the Bone Cement & Glue Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
Bone Cement & Glue Market Share (%), by Geographical Region
North America
Capturing nearly 35% of the global bone cement and glue market, North America is a leading region driven by cutting-edge healthcare infrastructure and early adoption of advanced surgical technologies. The presence of major market players further strengthens its position.
Europe
Europe accounts for approximately 30% of the market, benefiting from a robust healthcare network and rising cases of orthopedic diseases. Significant funding in research and innovation also bolsters the region’s market growth.
Asia Pacific
With about 25% market share, Asia Pacific is witnessing rapid growth fueled by urbanization, improved healthcare access, and heightened awareness of bone health issues. This makes it a key emerging market in the industry.
Middle East and Africa
Representing close to 5% of the market, the Middle East and Africa region is gradually expanding due to increased healthcare spending and enhancements in medical infrastructure.
Latin America
Holding roughly 5% of the market, Latin America’s growth is driven by rising investments in healthcare and a growing number of orthopedic surgeries across various countries in the region.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Bone Cement & Glue Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers:
- Aging population
- Increasing prevalence of musculoskeletal disorders
- Technological advancements in biomaterials
-
Rising demand for minimally invasive surgeries - The rising demand for minimally invasive surgeries (MIS) has been a significant driver in the global bone cement and glue market, revolutionizing orthopedic procedures and patient outcomes. MIS techniques involve smaller incisions compared to traditional open surgeries, resulting in reduced trauma to surrounding tissues, less post-operative pain, shorter hospital stays, and quicker recovery times for patients. These advantages have led to a growing preference among both patients and surgeons, thereby fueling the demand for specialized bone cement and glue solutions that cater to the unique requirements of MIS.
Orthopedic surgeries such as joint replacements (e.g., hip and knee) and spinal procedures (e.g., vertebroplasty and kyphoplasty) benefit greatly from MIS approaches, which rely heavily on effective fixation and stabilization of implants using bone cement and glue. Manufacturers have responded to this trend by developing advanced formulations that ensure optimal bonding strength, ease of application through small incisions, and compatibility with MIS instruments.
The shift towards minimally invasive techniques is supported by ongoing advancements in surgical tools, imaging technologies (such as fluoroscopy and navigation systems), and robotic-assisted surgery. These innovations enhance surgical precision, improve outcomes, and expand the scope of MIS across various orthopedic specialties.
From a market perspective, the rising demand for MIS has created opportunities for growth and innovation in the bone cement and glue sector. Companies are increasingly focusing on developing new products that meet the specific needs of minimally invasive procedures, including formulations with enhanced viscosity, setting times, and biocompatibility. This market trend is expected to continue driving advancements in orthopedic surgery techniques and contributing to the overall expansion of the bone cement and glue market globally.
Restraints:
- High cost of advanced bone cement and glue products
- Regulatory challenges and product approval processes
- Complications associated with cemented implants
-
Limited reimbursement policies in certain regions - Limited reimbursement policies in certain regions pose a significant restraint to the growth of the global bone cement and glue market. Reimbursement policies vary widely across countries and regions, influencing the affordability and accessibility of orthopedic procedures that require bone cement and glue products.
In some regions, reimbursement may not adequately cover the cost of advanced bone cement and glue technologies, which can be expensive due to their innovative formulations and materials. This disparity can discourage healthcare providers from adopting newer, more effective products in favor of more traditional and lower-cost options. As a result, patients may not have access to the latest advancements in orthopedic surgery, potentially impacting treatment The complex and often lengthy process of gaining reimbursement approval for new products can delay market entry and adoption, particularly for smaller manufacturers or companies introducing novel technologies. This regulatory hurdle requires extensive clinical evidence demonstrating the safety, efficacy, and cost-effectiveness of bone cement and glue products, which can be resource-intensive and time-consuming.
Variations in reimbursement policies can create disparities in healthcare delivery and patient care outcomes between regions with differing financial resources and healthcare priorities. This situation underscores the need for greater alignment and standardization of reimbursement policies across regions to promote equitable access to advanced orthopedic treatments worldwide.
Addressing the challenge of limited reimbursement policies requires collaboration among healthcare providers, policymakers, and industry stakeholders to advocate for fair reimbursement practices that support innovation, improve patient outcomes, and ensure sustainable growth of the bone cement and glue market globally.
Opportunities:
- Development of antibiotic-loaded bone cement
- Expansion into emerging markets
- Growing adoption of biocompatible and bioresorbable materials
-
Integration of 3D printing technology in product manufacturing - The integration of 3D printing technology in the manufacturing of bone cement and glue products represents a transformative advancement in the orthopedic industry. 3D printing, also known as additive manufacturing, allows for the precise fabrication of customized implants and medical devices, tailored to the specific anatomical requirements of individual patients. This level of customization enhances the fit and function of orthopedic implants, leading to improved surgical outcomes and patient satisfaction.
One of the primary advantages of 3D printing in the production of bone cement and glue products is the ability to create complex geometries and structures that are difficult or impossible to achieve with traditional manufacturing methods. This capability is particularly beneficial for developing porous implants that mimic the natural bone structure, promoting better integration and osseointegration. Additionally, 3D printing enables the incorporation of multiple materials within a single construct, allowing for the combination of bone cement with bioactive agents that can enhance healing and reduce the risk of infection.
The adoption of 3D printing technology also streamlines the production process, reducing lead times and costs associated with custom-made implants and surgical instruments. This efficiency is crucial in responding to the growing demand for personalized orthopedic solutions, driven by the increasing prevalence of musculoskeletal disorders and the aging population. Moreover, the ability to rapidly prototype and test new designs accelerates innovation and the introduction of novel products to the market.
Competitive Landscape Analysis
Key players in Global Bone Cement & Glue Market include:
- Stryker
- Zimmer Biomet
- Depuy Synthes
- Smith & Nephew
- Arthrex
- DJO Global
- Exactech
- Teknimed
- Heraeus Medical
- Cryolife
- Cardinal Health
- Trimph
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product Type
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Bone Cement & Glue Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Aging population
- Increasing prevalence of musculoskeletal disorders
- Technological advancements in biomaterials
- Rising demand for minimally invasive surgeries
- Restraints
- High cost of advanced bone cement and glue products
- Regulatory challenges and product approval processes
- Complications associated with cemented implants
- Limited reimbursement policies in certain regions
- Opportunities
- Development of antibiotic-loaded bone cement
- Expansion into emerging markets
- Growing adoption of biocompatible and bioresorbable materials
- Integration of 3D printing technology in product manufacturing
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Bone Cement & Glue Market, By Product Type, 2021 - 2031 (USD Million)
- Synthetic Bone Glue
- Natural Bone Glue
- Bone Cement & Glue Market, By Application, 2021 - 2031 (USD Million)
- Arthroplasty
- Total Knee Arthroplasty
- Total Hip Arthroplasty
- Total Shoulder Arthroplasty
- Kyphoplasty
- Vertebroplasty
- Bone Cement & Glue Market, By End User, 2021 - 2031 (USD Million)
- Hospitals
- Ambulatory Surgery Centers
- Clinics/Physician Offices
- Bone Cement & Glue Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Bone Cement & Glue Market, By Product Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Stryker
- Zimmer Biomet
- Depuy Synthes
- Smith & Nephew
- Arthrex
- DJO Global
- Exactech
- Teknimed
- Heraeus Medical
- Cryolife
- Cardinal Health
- Trimph
- Company Profiles
- Analyst Views
- Future Outlook of the Market