Bile Duct Cancer (Cholangiocarcinoma) Market

By Treatment Type;

Chemotherapy -[Gemcitabine-Based, Cisplatin-Based, Combination Therapies and Others], Targeted Therapy -[Epidermal Growth Factor Receptor (EGFR) Inhibitors, Vascular Endothelial Growth Factor (VEGF) Inhibitors and Others], Radiation Therapy, Immunotherapy, Surgery and Others

By Disease Type;

Intrahepatic Cholangiocarcinoma, Extrahepatic Cholangiocarcinoma, Perihilar Cholangiocarcinoma (Klatskin Tumors) and Distal Cholangiocarcinoma

By Distribution Channel;

Hospital Pharmacies, Retail Pharmacies and Online Pharmacies

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn902397518 Published Date: September, 2025 Updated Date: October, 2025

Bile Duct Cancer (Cholangiocarcinoma) Market Overview

Bile Duct Cancer (Cholangiocarcinoma) Market (USD Million)

Bile Duct Cancer (Cholangiocarcinoma) Market was valued at USD 404.47 million in the year 2024. The size of this market is expected to increase to USD 693.19 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 8.0%.


Bile Duct Cancer (Cholangiocarcinoma) Market

*Market size in USD million

CAGR 8.0 %


Study Period2025 - 2031
Base Year2024
CAGR (%)8.0 %
Market Size (2024)USD 404.47 Million
Market Size (2031)USD 693.19 Million
Market ConcentrationMedium
Report Pages344
404.47
2024
693.19
2031

Major Players

  • F. Hoffmann-La Roche Ltd
  • Pfizer Inc.
  • Merck & Co., Inc.
  • Bristol Myers Squibb Company
  • Novartis International AG
  • Bayer AG
  • AstraZeneca PLC
  • Eli Lilly and Company
  • AbbVie Inc.
  • Celgene Corporation

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Bile Duct Cancer (Cholangiocarcinoma) Market

Fragmented - Highly competitive market without dominant players


The Bile Duct Cancer (Cholangiocarcinoma) Market is gaining prominence with rising awareness and advancements in oncology research. Improved early detection rates have increased by nearly 20% due to biomarker-based screening and advanced imaging tools. This shift is enabling more accurate diagnosis and effective treatment options, driving significant adoption of innovative therapies.

Growing Focus on Targeted Therapies
The demand for targeted treatments is expanding, with over 35% of protocols incorporating precision medicine. These therapies directly address genetic mutations in tumor cells, improving patient outcomes while reducing harmful side effects. The emphasis on personalized medicine is redefining the approach to cholangiocarcinoma treatment.

Advancements in Immunotherapy
Adoption of immunotherapy has surged by approximately 30%, as more patients benefit from therapies that empower the immune system to fight tumor growth. Clinical trials have shown encouraging results, boosting confidence in these treatments. With expanding research, immunotherapy is positioned to play a stronger role in treatment pathways for bile duct cancer.

Investment in Research and Development
Nearly 40% of ongoing oncology projects now focus on rare cancers, including cholangiocarcinoma. Pharmaceutical and biotech companies are increasing funding toward next-generation drug discoveries. These R&D efforts are paving the way for breakthrough therapies that enhance survival and quality of life for patients.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Treatment Type
    2. Market Snapshot, By Disease Type
    3. Market Snapshot, By Distribution Channel
    4. Market Snapshot, By Region
  4. Bile Duct Cancer (Cholangiocarcinoma) Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Increasing incidence rates
        2. Advanced diagnostic technologies
        3. Growing healthcare expenditure
        4. Rising awareness campaigns
        5. Enhanced treatment options
      2. Restraints
        1. High treatment costs
        2. Limited early detection
        3. Insufficient research funding
        4. Complex regulatory approvals
        5. Low awareness levels
      3. Opportunities
        1. Emerging market potential
        2. Innovative drug developments
        3. Improved healthcare infrastructure
        4. Collaborations and partnerships
        5. Personalized medicine advancements
      4. PEST Analysis
        1. Political Analysis
        2. Economic Analysis
        3. Social Analysis
        4. Technological Analysis
      5. Porter's Analysis
        1. Bargaining Power of Suppliers
        2. Bargaining Power of Buyers
        3. Threat of Substitutes
        4. Threat of New Entrants
        5. Competitive Rivalry
  5. Market Segmentation
    1. Bile Duct Cancer (Cholangiocarcinoma) Market, By Treatment Type, 2021 - 2031 (USD Million)
      1. Chemotherapy
        1. Gemcitabine-Based
        2. Cisplatin-Based
        3. Combination Therapies
        4. Others
      2. Targeted Therapy
        1. Epidermal Growth Factor Receptor (EGFR) Inhibitors
        2. Vascular Endothelial Growth Factor (VEGF) Inhibitors
        3. Others
      3. Radiation Therapy
      4. Immunotherapy
      5. Surgery
      6. Others
    2. Bile Duct Cancer (Cholangiocarcinoma) Market, By Disease Type, 2021 - 2031 (USD Million)
      1. Intrahepatic Cholangiocarcinoma
      2. Extrahepatic Cholangiocarcinoma
      3. Perihilar Cholangiocarcinoma (Klatskin Tumors)
      4. Distal Cholangiocarcinoma
    3. Bile Duct Cancer (Cholangiocarcinoma) Market, By Distribution Channel, 2021 - 2031 (USD Million)
      1. Hospital Pharmacies
      2. Retail Pharmacies
      3. Online Pharmacies
    4. Bile Duct Cancer (Cholangiocarcinoma) Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Pfizer Inc.
      2. GlaxoSmithKline plc
      3. AbbVie Inc.
      4. Novartis AG
      5. Eli Lilly and Company
      6. F. Hoffmann-La Roche Ltd.
      7. Bristol-Myers Squibb Company
      8. Merck & Co., Inc.
      9. Johnson & Johnson
      10. Mylan N.V.
      11. Teva Pharmaceutical Industries Ltd.
      12. Sanofi
      13. Delcath Systems Inc.
      14. Kyowa Hakko Kirin Co., Ltd.
      15. Bayer AG
  7. Analyst Views
  8. Future Outlook of the Market