Avascular Necrosis Market

By Type;

Trauma Related Avascular Necrosis (AVN) and Non-Trauma Related Avascular Necrosis (AVN)

By Site;

Hip Bone, Knee, and Shoulder

By Diagnosis;

Imaging and Biopsy

By End User;

Hospitals & Clinics, Diagnostic Centers, and Ambulatory Surgical Centers

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn568450981 Published Date: August, 2025

Avascular Necrosis Market Overview

Avascular Necrosis Market (USD Million)

Avascular Necrosis Market was valued at USD 781.46 million in the year 2024. The size of this market is expected to increase to USD 1,190.63 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 6.2%.


Avascular Necrosis Market

*Market size in USD million

CAGR 6.2 %


Study Period2025 - 2031
Base Year2024
CAGR (%)6.2 %
Market Size (2024)USD 781.46 Million
Market Size (2031)USD 1,190.63 Million
Market ConcentrationMedium
Report Pages384
781.46
2024
1,190.63
2031

Major Players

  • Sanofi
  • Bayer Healthcare AG
  • Boehringer Ingelheim GmbH
  • Pfizer Inc.
  • Merck KGaA
  • Stryker Corporation
  • Medtronic PLC
  • Aurobindo Pharma
  • Integra LifeSciences Corporation
  • Zimmer Biomet Holdings
  • Wright Medical Group N.V.
  • Grifols SA
  • Smith & Nephew
  • Ethicon Inc.

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Avascular Necrosis Market

Fragmented - Highly competitive market without dominant players


The Avascular Necrosis Market is propelled by strong technological advancements, as more than 60% of R&D focuses on stem-cell-based and scaffold-assisted regeneration techniques. These treatments enhance efficacy, boosting bone perfusion and structural recovery. Successful clinical outcomes are spurring market growth and earning clinician trust.

Clinical Collaborations Enhancing Trial Success
About 50% of innovative therapies arise from collaboration and partnerships between regenerative medicine developers and orthopedic research institutes. These coordinated strategies harmonize clinical protocols, validate biomarker use, and confirm functional outcomes. Such partnerships are widening expansion of therapy options.

Smart Biomaterials Reinforcing Bone Repair
Over 55% of innovation efforts centre on innovation in composite implants—like bioactive ceramics, angiogenic coatings, and drug-eluting scaffolds. These advances support vascular ingrowth, maintain structural integrity, and delay disease progression. Material-driven developments are reinforcing the market’s future outlook and sustaining growth in patient recovery.

AI‑Powered Follow-Up Tools Elevating Care Precision
With over 50% of providers adopting AI-assisted imaging and remote monitoring platforms, clinicians can better track lesion evolution and adjust treatment plans in real time. These tools deliver predictive alerts and outcome insights. Merging digital diagnostics with core therapies exemplifies technological advancements, fostering sustained growth and a confident future outlook.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Type
    2. Market Snapshot, By Site
    3. Market Snapshot, By Diagnosis
    4. Market Snapshot, By End User
    5. Market Snapshot, By Region
  4. Avascular Necrosis Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Demand growth

        2. Rehabilitation Programs

        3. Market expansion

        4. Improved Surgical Precision

      2. Restraints
        1. High initial investment

        2. Regulatory hurdles

        3. Supply chain disruptions

        4. Competitive pressures

      3. Opportunities
        1. Sustainability trends

        2. Strategic partnerships

        3. Consumer awareness

        4. Product diversification

    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Avascular Necrosis Market, By Type, 2021 - 2031 (USD Million)
      1. Trauma Related Avascular Necrosis (AVN)
      2. Non-Trauma Related Avascular Necrosis (AVN)
    2. Avascular Necrosis Market, By Site, 2021 - 2031 (USD Million)
      1. Hip Bone
      2. Knee
      3. Shoulder
    3. Avascular Necrosis Market, By Diagnosis, 2021 - 2031 (USD Million)
      1. Imaging
      2. Biopsy
    4. Avascular Necrosis Market, By End User, 2021 - 2031 (USD Million)
      1. Hospitals & Clinics
      2. Diagnostic Centers
      3. Ambulatory Surgical Centers
    5. Avascular Necrosis Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Sanofi
      2. Bayer Healthcare AG
      3. Boehringer Ingelheim GmbH
      4. Pfizer Inc.
      5. Merck KGaA
      6. Stryker Corporation
      7. Medtronic PLC
      8. Aurobindo Pharma
      9. Integra LifeSciences Corporation
      10. Zimmer Biomet Holdings
      11. Wright Medical Group N.V.
      12. Grifols SA
      13. Smith & Nephew
      14. Ethicon Inc.
  7. Analyst Views
  8. Future Outlook of the Market