5-Hydroxytryptophan (5-HTP) Market

By Source Type;

Plant-Derived (Griffonia Simplicifolia), Synthetic Chemical and Microbial Fermentation

By Form;

Powder (>95% Potency), Capsules & Tablets, Liquid Extracts and Gummies & Functional Foods

By Application;

Dietary Supplements, Medical/Pharmaceutical, Food & Beverage Fortification, Cosmetics & Personal Care and Others

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn575164251 Published Date: October, 2025 Updated Date: November, 2025

5-Hydroxytryptophan (5-HTP) Market Overview

5-Hydroxytryptophan (5-HTP) Market (USD Million)

5-Hydroxytryptophan (5-HTP) Market was valued at USD 69,324.39 million in the year 2024. The size of this market is expected to increase to USD 112,050.13 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 7.1%.


5-Hydroxytryptophan (5-HTP) Market

*Market size in USD million

CAGR 7.1 %


Study Period2025 - 2031
Base Year2024
CAGR (%)7.1 %
Market Size (2024)USD 69,324.39 Million
Market Size (2031)USD 112,050.13 Million
Market ConcentrationMedium
Report Pages345
69,324.39
2024
112,050.13
2031

Major Players

  • Natrol LLC
  • NOW Foods
  • Nature's Way Products, LLC
  • Jarrow Formulas, Inc.
  • Life Extension
  • Swanson Health Products
  • Solaray
  • Doctor's Best, Inc.
  • Pure Encapsulations, Inc.
  • Douglas Laboratories

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

5-Hydroxytryptophan (5-HTP) Market

Fragmented - Highly competitive market without dominant players



The 5-Hydroxytryptophan (5-HTP) Market is experiencing steady growth as consumers seek natural solutions for mood, sleep, and appetite regulation. Known for boosting serotonin levels, 5-HTP has become a core ingredient in the wellness industry. Currently, nearly 55% of supplement formulations focus on stress reduction and emotional balance, underlining its strong adoption in nutraceutical applications.

Strong Role in Mental Well-Being and Sleep Care
Rising concerns around depression, anxiety, and insomnia are accelerating the demand for 5-HTP-based supplements. Research highlights that about 48% of users consume 5-HTP for sleep improvement and mental relaxation. Its positioning as a natural alternative to synthetic medications is driving consumer trust, making it one of the most reliable options in the mental health supplement category.

Weight Management and Lifestyle Applications
Beyond mental health, 5-HTP plays a key role in weight management solutions. Around 40% of consumers use 5-HTP for appetite control and to curb food cravings, aligning with healthier lifestyle choices. With fitness-conscious consumers increasingly prioritizing multi-benefit supplements, 5-HTP has gained importance in formulations that address both physical and emotional well-being.

Shift Toward Natural and Plant-Based Ingredients
The market is witnessing a notable rise in plant-sourced products, with nearly 60% of buyers preferring natural and clean-label solutions. Derived mainly from Griffonia simplicifolia seeds, 5-HTP is widely accepted in premium formulations. Its integration with vitamins, minerals, and herbal extracts reflects the rising popularity of synergistic supplement blends designed for holistic health.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Source Type
    2. Market Snapshot, By Form
    3. Market Snapshot, By Application
    4. Market Snapshot, By Region
  4. 5-Hydroxytryptophan (5-HTP) Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Increasing Mental Health Awareness
        2. Rising Demand for Natural Supplements
        3. Growth in E-commerce Channels
      2. Restraints
        1. Potential Side Effects
        2. Regulatory Challenges
        3. High Product Costs
      3. Opportunities
        1. Expansion in Emerging Markets
        2. Innovative Product Formulations
        3. Partnerships with Healthcare Providers
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. 5-Hydroxytryptophan (5-HTP) Market, By Source Type, 2021 - 2031 (USD Million)
      1. Plant-Derived (Griffonia Simplicifolia)
      2. Synthetic Chemical
      3. Microbial Fermentation
    2. 5-Hydroxytryptophan (5-HTP) Market, By Form, 2021 - 2031 (USD Million)
      1. Powder (>95% Potency)
      2. Capsules & Tablets
      3. Liquid Extracts
      4. Gummies & Functional Foods
    3. 5-Hydroxytryptophan (5-HTP) Market, By Application, 2021 - 2031 (USD Million)
      1. Dietary Supplements
      2. Medical/Pharmaceutical
      3. Food & Beverage Fortification
      4. Cosmetics & Personal Care
      5. Others
    4. 5-Hydroxytryptophan (5-HTP) Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. NOW Foods
      2. Natrol LLC
      3. Linnea SA
      4. Nature’s Way Products
      5. Cactus Botanics
      6. SanHerb (Chengdu SanHerb Bioscience)
      7. Shaanxi Jiahe Phytochem
      8. Bee Health
      9. Douglas Laboratories
      10. Life Extension
      11. Swanson Health Products
      12. Pure Encapsulations
      13. Jarrow Formulas
      14. Solgar Inc.
      15. Nutraceutical International
  7. Analyst Views
  8. Future Outlook of the Market