Convalescent Plasma Therapy Market
By Antibody Type;
Immunoglobulin M (IgM), Immunoglobulin G (IgG) and Immunoglobulin A (IgA)By Application;
Prophylaxis and TreatmentBy End-User;
Hospitals & Clinics and Laboratories & Research InstitutesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Convalescent Plasma Therapy Market Overview
Convalescent Plasma Therapy Market (USD Million)
Convalescent Plasma Therapy Market was valued at USD 3.43 million in the year 2024. The size of this market is expected to increase to USD 9.71 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 16.0%.
Convalescent Plasma Therapy Market
*Market size in USD million
CAGR 16.0 %
| Study Period | 2025 - 2031 |
|---|---|
| Base Year | 2024 |
| CAGR (%) | 16.0 % |
| Market Size (2024) | USD 3.43 Million |
| Market Size (2031) | USD 9.71 Million |
| Market Concentration | Low |
| Report Pages | 337 |
Major Players
- Bio Farma
- Grifols
- Hilton Pharma
- Biotest
- BPL
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Convalescent Plasma Therapy Market
Fragmented - Highly competitive market without dominant players
Convalescent Plasma Therapy Market is witnessing strong momentum, driven by the demand for effective antibody-based treatments that aid recovery in critical cases. By leveraging plasma rich in antibodies, this therapy ensures targeted care and improved patient outcomes. More than 65% of healthcare providers have recognized its potential, reflecting its steady adoption across healthcare systems.
Growing Focus on Personalized Care
Nearly 52% of patients are seeking personalized treatment options, positioning plasma therapy as a key component in precision healthcare. By matching donor antibody profiles with patient needs, this therapy offers customized solutions that align with the global trend of individualized care, making it an essential medical advancement.
Advancements Strengthening Market Adoption
Innovations in plasma collection, storage, and transfusion are driving greater adoption. About 48% of manufacturers are investing in advanced purification technologies and improved safety measures. These innovations ensure reliability, enhance large-scale usability, and make treatments safer and more efficient for both patients and providers.
Emphasis on Regulations and Standards
Stringent regulatory requirements are shaping the market, with close to 41% of approvals demanding compliance with enhanced safety protocols. These standards build consumer trust and maintain consistency in quality, ensuring that plasma therapies meet the highest healthcare benchmarks worldwide.
Growth Prospects and Industry Outlook
Convalescent Plasma Therapy Market continues to expand as research, awareness campaigns, and clinical applications grow. More than 58% of hospitals are evaluating or integrating plasma therapy into their protocols. With rising awareness and infrastructure support, the market is set for steady growth in the years ahead.
Convalescent Plasma Therapy Market Key Takeaways
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Increased research on passive immunization has sustained interest in convalescent plasma therapy as a treatment option for emerging infectious diseases.
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Wider clinical trials and regulatory approvals are driving global standardization in plasma collection, antibody screening, and transfusion protocols.
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Advancements in plasma separation and storage technologies are enhancing the efficiency and safety of plasma-derived therapies.
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Growing collaboration between biopharma companies and blood banks is improving plasma availability and expanding therapeutic applications beyond viral infections.
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High demand during pandemic outbreaks demonstrated the market’s potential in crisis response, leading to the development of scalable plasma banking infrastructure.
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Emergence of alternative therapies such as monoclonal antibodies and antiviral drugs is shaping competition and influencing long-term adoption rates.
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Regulatory focus on safety and ethical sourcing is strengthening quality assurance and donor management systems across major healthcare markets.
Convalescent Plasma Therapy Market Recent Developments
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Convalescent plasma therapy has demonstrated promising outcomes in clinical trials, with potential to reduce mortality rates and enhance recovery outcomes, particularly in COVID-19 patients. Its proven effectiveness and safety in alleviating symptoms and supporting faster recovery have led to increased adoption in hospitals and healthcare settings worldwide.
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In August 2020, the U.S. FDA issued an Emergency Use Authorization (EUA) for COVID-19 convalescent plasma, enabling healthcare providers to treat hospitalized patients with COVID-19. Despite the authorization, the treatment faced scrutiny due to mixed trial results regarding its efficacy in improving patient outcomes.
Convalescent Plasma Therapy Market Segment Analysis
In this report, Convalescent Plasma Therapy Market has been segmented by Antibody Type, Application, End-User, and Geography.
Convalescent Plasma Therapy Market, Segmentation by Antibody Type
The Antibody Type segment includes Immunoglobulin M (IgM), Immunoglobulin G (IgG), and Immunoglobulin A (IgA). These antibodies play a significant role in the effectiveness of convalescent plasma therapy, which is used to treat patients with various infectious diseases. Different antibody types have distinct characteristics that influence their therapeutic potential in managing diseases such as COVID-19 and other viral infections.
Immunoglobulin M (IgM)
IgM is the first antibody produced in response to an infection and plays a key role in the initial immune defense. It is often used in prophylaxis and for treating patients in the early stages of infection.
Immunoglobulin G (IgG)
IgG is the most abundant antibody in the blood and provides long-lasting immunity. It is primarily used in treatment protocols, especially for patients with severe or chronic infections, offering enhanced protection against pathogens.
Immunoglobulin A (IgA)
IgA plays a critical role in mucosal immunity, particularly in protecting the respiratory and gastrointestinal tracts. It is used in specific applications, such as for respiratory infections or gastrointestinal disorders, to bolster the immune system.
Convalescent Plasma Therapy Market, Segmentation by Application
The Application segment includes Prophylaxis and Treatment. These applications highlight the use of convalescent plasma therapy for both preventing infections and managing patients who have already contracted a disease. The market demand is driven by the increasing adoption of plasma therapy for treating viral infections, particularly during disease outbreaks.
Prophylaxis
In prophylaxis, convalescent plasma therapy is used to provide passive immunity to individuals exposed to infectious diseases. This is particularly beneficial in preventing the spread of diseases like COVID-19, where rapid immune response is crucial.
Treatment
In treatment, convalescent plasma is used to treat patients who have already contracted a disease. This application is critical in managing severe infections and is especially vital for patients with compromised immune systems or in critical care settings.
Convalescent Plasma Therapy Market, Segmentation by End-User
The End-User segment includes Hospitals & Clinics and Laboratories & Research Institutes. These settings are central to the delivery and research of convalescent plasma therapy, with hospitals providing immediate treatment and research institutes advancing knowledge on the therapy's efficacy and safety.
Hospitals & Clinics
Hospitals and clinics are the primary end-users of convalescent plasma therapy, administering the treatment to patients in critical and emergency settings. These institutions play a significant role in the clinical application of plasma therapy for infection control and recovery.
Laboratories & Research Institutes
Laboratories and research institutes are essential for advancing convalescent plasma therapy. They conduct studies on plasma's therapeutic potential, safety, and effectiveness, paving the way for the broader adoption of plasma-based treatments in healthcare.
Convalescent Plasma Therapy Market, Segmentation by Geography
The Geography segment includes North America, Europe, Asia Pacific, Middle East & Africa, and Latin America. North America leads the market due to high healthcare investments, advanced medical research, and widespread adoption of plasma therapy for viral infections like COVID-19. Europe and Asia Pacific follow with increasing interest in plasma-based treatments for emerging infections.
Regions and Countries Analyzed in this Report
North America
North America is the largest market for convalescent plasma therapy, driven by strong healthcare infrastructure, significant research funding, and the adoption of plasma-based treatments for diseases like COVID-19.
Europe
Europe is witnessing steady growth, supported by increasing healthcare investments and a growing focus on improving treatment options for infectious diseases. Countries such as Germany, France, and the UK are leading this demand.
Asia Pacific
Asia Pacific is expected to experience rapid growth due to increasing healthcare access, a rising prevalence of infectious diseases, and the expanding availability of plasma-based treatments in emerging economies like China and India.
Middle East & Africa
The Middle East & Africa market is gradually expanding, with healthcare improvements and rising interest in novel treatments like convalescent plasma therapy contributing to growth in countries like Saudi Arabia and the UAE.
Latin America
Latin America is experiencing moderate growth, particularly in Brazil and Mexico, where there is increasing awareness of the benefits of plasma therapy for treating viral infections and supporting recovery.
Convalescent Plasma Therapy Market Forces
This report provides an in depth analysis of various factors that impact the dynamics of Convalescent Plasma Therapy Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces Drivers, Restraints, and Opportunities affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
| Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential |
|---|---|---|---|---|---|
| High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development | |
| Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance |
| Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances |
Drivers, Restraints and Opportunity Analysis
Drivers :
- Rising incidence of infectious diseases
- Growing awareness and government support
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Limited treatment options for certain diseases - Convalescent Plasma Therapy Market is significantly impacted by the limited treatment options available for certain diseases, particularly emerging infectious diseases and conditions where standard treatments are ineffective. Convalescent plasma therapy offers a critical alternative for these scenarios, utilizing antibodies from recovered patients to combat active infections in others. This approach is particularly valuable in situations where antiviral drugs or vaccines are not yet available, providing a stopgap solution that can reduce disease severity and improve patient outcomes. The reliance on convalescent plasma therapy in such cases underscores its importance as a therapeutic option and drives demand within the market.
The dependence on convalescent plasma therapy also highlights several challenges, including the variability in antibody quality and quantity from different donors, logistical complexities in plasma collection and storage, and the need for rapid mobilization during outbreaks. Moreover, as a biologic treatment, it requires stringent regulatory oversight and robust clinical protocols to ensure safety and efficacy. Despite these challenges, the urgent need for effective treatments in the face of limited alternatives continues to propel the growth of the convalescent plasma therapy market, fostering innovation and improvements in plasma therapy techniques and infrastructure. This dynamic underscores the market's potential to address critical healthcare gaps while highlighting areas for ongoing development and optimization.
Restraints :
- Limited efficacy and safety concerns
- Stringent regulatory requirements
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Logistics and donor availability - The logistics and donor availability are critical components shaping the Convalescent Plasma Therapy Market. Efficient logistics systems are essential for the collection, storage, and transportation of convalescent plasma to ensure its efficacy and safety. This involves maintaining cold chain logistics, proper labeling, and timely distribution to healthcare facilities. Any disruptions in the supply chain can significantly impact the availability and effectiveness of the therapy. Moreover, the integration of advanced technologies for plasma screening and tracking is enhancing the reliability of logistics operations, ensuring that the plasma remains viable from donation to transfusion.
Donor availability is another crucial factor influencing the market. The success of convalescent plasma therapy depends on a steady supply of plasma from recovered patients who have developed the necessary antibodies. Public awareness campaigns, incentives for donors, and streamlined donation processes are vital to maintaining an adequate donor pool. Additionally, the establishment of donor registries and collaboration with blood banks and health organizations are essential strategies to ensure a consistent and reliable supply. Challenges such as donor eligibility criteria, varying recovery rates, and geographical disparities in donor availability need to be addressed to optimize the donor base and meet the growing demand for convalescent plasma therapy globally.
Opportunities :
- Technological advancements
- Development of new applications
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Increasing focus on personalized medicine - Convalescent Plasma Therapy Market is experiencing significant growth due to an increasing focus on personalized medicine. Personalized medicine tailors medical treatment to the individual characteristics of each patient, and convalescent plasma therapy fits well into this paradigm by using plasma from recovered individuals whose antibodies are specifically suited to combat the pathogens in the recipient's body. This targeted approach enhances the efficacy of the treatment, providing a more effective and personalized therapeutic option for patients suffering from infectious diseases. The ability to match plasma donors and recipients based on specific antibody profiles can lead to better outcomes and faster recovery times.
Advancements in genomic and proteomic technologies are facilitating the identification of optimal donors and the precise measurement of antibody levels and specificities, which is crucial for the success of personalized plasma therapy. The growing database of immunological profiles from recovered patients allows for a more strategic selection of plasma, aligning with the principles of personalized medicine. This shift towards personalized treatment is not only improving patient outcomes but also driving innovation and investment in the convalescent plasma therapy market, as stakeholders recognize the potential for tailored therapies to address complex and diverse healthcare challenges.
Convalescent Plasma Therapy Market Competitive Landscape Analysis
Convalescent Plasma Therapy Market is evolving through competitive intensity shaped by continuous collaboration, strategic partnerships, and growing innovation. The market has seen rising attention from healthcare providers and biopharmaceutical players focusing on therapies that accelerate growth. Increasing adoption of plasma-based treatments and collective research initiatives highlight how competitive factors influence both short-term positioning and long-term strategies.
Market Structure and Concentration
The market shows a moderate to high level of concentration, with leading institutions and companies leveraging mergers and collaboration to reinforce their positions. Competition is defined by specialized research hubs and regional blood banks coordinating strategic partnerships. Market leaders focus on building sustainable growth through diversified portfolios and securing access to plasma supplies.
Brand and Channel Strategies
Key participants are developing robust strategies to enhance brand visibility and streamline distribution channels. Partnerships with healthcare networks and digital platforms support expansion in clinical settings. Communication efforts emphasize trust, while innovation in service delivery and donor engagement helps improve channel efficiency. Strong brand equity is becoming a central factor in long-term growth.
Innovation Drivers and Technological Advancements
Cutting-edge technological advancements drive competitiveness in the plasma therapy sector. Automated collection systems, enhanced testing technologies, and digital innovation enable safer and faster processing. Research-focused strategies emphasize new methods to improve efficacy while lowering risks. Continuous collaboration between institutions and biopharma firms fosters developments that reinforce clinical reliability and accelerate treatment acceptance.
Regional Momentum and Expansion
Regional expansion plays a decisive role in shaping market direction, with different healthcare systems pursuing tailored strategies. Advanced economies prioritize large-scale collaboration, while emerging regions focus on strengthening plasma collection and distribution. Growth momentum is supported by academic initiatives and donor engagement programs, with partnerships enhancing access and sustaining clinical adoption trends across diverse geographies.
Future Outlook
The future outlook indicates steady growth, as continuous innovation and cross-sector collaboration improve efficiency and treatment reach. Integration of digital monitoring and plasma screening technologies will reshape strategies for safety and scalability. With broader regional expansion and strengthened institutional ties, the market is positioned to consolidate its role in advanced therapeutic landscapes over the next decade.
Key players in Convalescent Plasma Therapy Market include:
- Grifols
- CSL Behring
- Takeda
- Octapharma
- Kedrion
- LFB
- Biotest
- ADMA Biologics
- Sanquin Plasma Products
- Bio Farma
- BPL (Bharat Plasma / BPL Ltd.)
- Orthosera
- GC Biopharma
- New York Blood Center
- Cerus Corporation
In this report, the profile of each market player provides following information:
- Market Share Analysis
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Antibody Type
- Market Snapshot, By Application
- Market Snapshot, By End-User
- Market Snapshot, By Region
- Convalescent Plasma Therapy Market Forces
- Drivers, Restraints and Opportunities
- Drivers
- Rising incidence of infectious diseases
- Growing awareness and government support
- Limited treatment options for certain diseases
- Restraints
- Limited efficacy and safety concerns
- Stringent regulatory requirements
- Logistics and donor availability
- Opportunities
- Technological advancements
- Development of new applications
- Increasing focus on personalized medicine
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
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Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Convalescent Plasma Therapy Market, By Antibody Type, 2021 - 2031 (USD Million)
- Immunoglobulin M (IgM)
- Immunoglobulin G (IgG)
- Immunoglobulin A (IgA)
- Convalescent Plasma Therapy Market, By Application, 2021 - 2031 (USD Million)
- Prophylaxis
- Treatment
- Convalescent Plasma Therapy Market, By End-User, 2021 - 2031 (USD Million)
- Hospitals & Clinics
- Laboratories & Research Institutes
- Convalescent Plasma Therapy Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Convalescent Plasma Therapy Market, By Antibody Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Grifols
- CSL Behring
- Takeda (BPL)
- Octapharma
- Kedrion
- LFB
- Biotest
- ADMA Biologics
- Sanquin Plasma Products
- Bio Farma
- BPL (Bharat Plasma / BPL Ltd.)
- Orthosera
- GC Biopharma
- New York Blood Center
- Cerus Corporation
- Company Profiles
- Analyst Views
- Future Outlook of the Market

