Cholera Vaccines Market
By Type;
Dukoral, Shanchol and EuvicholBy Route of Administration;
OralBy End Users;
Hospitals, Homecare, Specialty Clinics and OthersBy Distribution Channel;
Hospital Pharmacy, Online Pharmacy and Retail PharmacyBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Cholera Vaccine Market Overview
Cholera Vaccine Market (USD Million)
Cholera Vaccine Market was valued at USD 157.06 million in the year 2024. The size of this market is expected to increase to USD 383.45 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 13.6%.
Cholera Vaccines Market
*Market size in USD million
CAGR 13.6 %
| Study Period | 2025 - 2031 |
|---|---|
| Base Year | 2024 |
| CAGR (%) | 13.6 % |
| Market Size (2024) | USD 157.06 Million |
| Market Size (2031) | USD 383.45 Million |
| Market Concentration | Low |
| Report Pages | 354 |
Major Players
- Emergent BioSolutions, Inc
- Astellas Pharma, Inc
- Sanofi, Eubiologics Co., Ltd
- Johnson & Johnson
- Celldex Therapeutics
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Cholera Vaccines Market
Fragmented - Highly competitive market without dominant players
The Cholera Vaccine Market is gaining significance as a cornerstone of disease prevention. With cholera outbreaks persisting worldwide, around 70% of demand stems from mass immunization and outbreak response programs. Stronger healthcare systems and awareness campaigns are reinforcing the momentum of this vital market.
Rising Demand Factors
Urbanization and unsafe water conditions are fueling about 65% of new vaccine interventions across vulnerable regions. Governments, NGOs, and global health bodies are increasingly prioritizing oral cholera vaccines to shield high-risk communities. This rising focus positions cholera vaccination as an essential part of long-term preventive care.
Technological Advancements
Breakthroughs in oral vaccine formulations have simplified immunization processes, with over 55% of supply now relying on oral doses. These improvements not only extend protection but also reduce storage and distribution barriers. Such innovation is broadening vaccine reach and enhancing patient compliance.
Funding and Awareness Programs
Global initiatives and funding collaborations account for nearly 60% of total vaccine distribution. Partnerships between international health agencies and private entities are fostering awareness, ensuring populations recognize the importance of timely vaccination. These efforts continue to drive accessibility and build sustainable demand growth.
Cholera Vaccines Market Key Takeaways
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Global demand for cholera vaccines is escalating due to rising outbreaks in regions with inadequate sanitation and infrastructure, particularly in Africa and South Asia.
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Vaccine shortages persist, with current global demand estimated at 100 million doses annually, while production capacity remains limited, exacerbating public health challenges.
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Single-dose regimens are being prioritized to extend limited vaccine supplies, reflecting a strategic shift towards more efficient use of resources in outbreak responses.
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Bharat Biotech's Hillchol, a new oral cholera vaccine, has demonstrated strong efficacy and safety in Phase III trials, offering a promising solution to address global vaccine shortages.
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North America leads the market, driven by advanced healthcare infrastructure and high awareness, while India plays a pivotal role as both a high-burden country and a major vaccine producer.
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Public health initiatives, including mass vaccination campaigns and international collaborations, are essential to controlling cholera outbreaks and reducing mortality rates.
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Climate change and ongoing conflicts are intensifying the frequency and severity of cholera outbreaks, highlighting the need for integrated approaches combining vaccination with improved water, sanitation, and hygiene (WASH) efforts.
Cholera Vaccine Market Recent Developments
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In November 2022, the Government of Canada announced a CAD 15 million (USD 11.2 million) contribution to a Pan American Health Organization (PAHO) initiative aimed at boosting vaccine production capacity in Latin America and the Caribbean. The program focuses on producing a wide range of vaccines, including the cholera vaccine, to strengthen regional healthcare resilience.
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In June 2022, the Ministry of Health and partners initiated an oral cholera vaccination campaign in Juba County, Central Equatoria State. This campaign forms part of a preventive strategy to curb cholera outbreaks in identified hotspot areas.
Cholera Vaccines Market Segment Analysis
In this report, the Cholera Vaccines Market has been segmented by Type, Route of Administration, End Users, Distribution Channel and Geography.
Cholera Vaccines Market, Segmentation by Type
The Type axis differentiates oral cholera vaccines by antigen composition, dosing schedules, and labeling relevant to routine and reactive campaigns. Health agencies weigh programmatic fit, co-administration guidance, and stability profiles alongside supply visibility and financing windows. Manufacturers compete on volume commitments, regional registrations, and sustained technology transfer to strengthen preparedness.
Dukoral
Dukoral is positioned for travelers and select public health use, emphasizing well-characterized formulations, clear dose scheduling, and robust pharmacovigilance. Procurement focuses on quality documentation, storage reliability, and supportive healthcare provider education for adherence. Stakeholders value predictable supply planning and integration with pre-travel and occupational health services.
Shanchol
Shanchol is widely used in mass immunization programs due to campaign suitability, streamlined two-dose regimens, and proven programmatic performance. Public buyers emphasize dose availability, field practicality, and coordination with WASH initiatives during outbreaks. Vendor support around training, AEFI monitoring, and rapid dispatch strengthens operational impact.
Euvichol
Euvichol supports large-scale campaigns through high-volume manufacturing and program-aligned packaging that eases field deployment. Decision makers prioritize scalable supply, regulatory harmonization, and campaign logistics across varied terrains. Collaboration with global procurement agencies, coupled with cold-chain resilience, underpins consistent access in surge scenarios.
Cholera Vaccines Market, Segmentation by Route of Administration
The Route of Administration reflects delivery models that minimize needle-associated barriers, enable rapid community outreach, and simplify training requirements for campaign staff. Program performance depends on last-mile cold chain, dose interval adherence, and microplanning that aligns with surveillance data and seasonality. Integrated communication strategies and accessible post-vaccination guidance reinforce uptake and confidence.
Oral
Oral delivery streamlines mass administration with simplified logistics, reduced need for clinical infrastructure, and family-centered outreach in crowded settings. It supports school-based drives and door-to-door initiatives where rapid coverage is essential. Programs benefit from easy task shifting, scalable staff training, and consistent cold-chain monitoring using temperature indicators and digital tracking.
Cholera Vaccines Market, Segmentation by End Users
The End Users lens captures where vaccination is delivered and managed across facility-based and community-based models. Stakeholders emphasize inventory visibility, AEFI reporting, and data interoperability with surveillance platforms. Partnerships with NGOs and local authorities help align microplans, secure staffing, and ensure equitable access for high-risk populations.
Hospitals
Hospitals integrate cholera vaccination into travel medicine, pre-exposure counseling, and outbreak response hubs with robust oversight. Strengths include cold storage reliability, clinician-led eligibility assessment, and adverse event management pathways. These settings also support data quality, follow-up dosing, and linkage to laboratory confirmation where indicated.
Homecare
Homecare models extend reach to vulnerable or mobility-constrained groups through community health workers. Success relies on micro-cold chain, clear dose documentation, and culturally appropriate risk communication. Digital tools assist with address mapping, reminders, and outcome tracking to sustain adherence.
Specialty Clinics
Specialty clinics—including travel clinics and immunization centers—offer tailored counseling and streamlined appointment workflows. They emphasize stock availability, record integration, and multilingual materials to serve diverse cohorts. Collaboration with pharmacies and public programs ensures continuity during supply constraints.
Others
Others encompass outreach posts, camps, and pop-up sites coordinated with local NGOs and public health teams. Priorities include rapid site setup, simplified wastage control, and reliable cold-chain validation. Flexible staffing and mobile data capture reinforce coverage in hard-to-reach areas.
Cholera Vaccines Market, Segmentation by Distribution Channel
The Distribution Channel segmentation reflects how vaccines and related services reach patients, travelers, and public programs. Procurement agencies and private providers balance stock rotation, serialization, and temperature monitoring with counseling and appointment management. Clear eligibility messaging and reimbursement workflows strengthen continuity of supply.
Hospital Pharmacy
Hospital pharmacy provides integrated inventory governance, validated storage, and clinician-aligned dispensing for facility-based vaccination. Emphasis on batch traceability, recall readiness, and coordinated scheduling helps maintain adherence. Linkages to infection prevention teams enable fast response during local outbreaks.
Online Pharmacy
Online pharmacy channels support appointment booking, counseling, and routing to certified administration sites. Digital triage and reminder systems reduce missed doses and improve convenience for travelers. Transparent stock visibility and temperature-compliant fulfillment underpin confidence and planning.
Retail Pharmacy
Retail pharmacy expands access with extended hours, broad geographic coverage, and streamlined walk-in pathways. Success depends on cold-chain integrity, trained staff, and interoperable records that sync with national registries. Co-delivery with routine immunizations and travel vaccines improves efficiency and uptake.
Cholera Vaccines Market, Segmentation by Geography
Geography shapes adoption through epidemiological risk, health-system capacity, and funding mechanisms that determine campaign cadence and preparedness. Regions with robust surveillance, efficient last-mile logistics, and clear policy frameworks scale both routine and reactive programs. Competitive positioning hinges on local partnerships, regulatory alignment, and predictable manufacturing supply synchronized with seasonal risk.
Regions and Countries Analyzed in this Report
North America
Demand is driven by travel medicine, preparedness for public health contingencies, and institutional protocols for humanitarian deployments. Stakeholders prioritize regulatory compliance, robust pharmacovigilance, and integrated health record systems. Retail and hospital channels coordinate inventory and counseling to ensure timely access during advisories.
Europe
Procurement aligns with coordinated public health frameworks, strong surveillance networks, and guidance for travelers and high-risk groups. Emphasis on cold-chain documentation, multilingual risk communication, and cross-border data sharing supports consistent programs. Partnerships with NGOs facilitate responsive supply for overseas missions.
Asia Pacific
Significant endemic burden and dense urban settings elevate the need for scalable campaign logistics, community engagement, and reliable last-mile delivery. Governments and partners focus on microplanning, outreach to informal settlements, and integration with WASH initiatives. Local manufacturing and regulatory harmonization improve speed to deployment.
Middle East & Africa
Outbreak-prone areas rely on strategic stockpiles, rapid campaign activation, and resilient cold-chain infrastructure under challenging climates. Programs prioritize community trust, clear AEFI reporting, and coordinated partner logistics. Supplier presence and regional depots enhance responsiveness during surges.
Latin America
Risk varies by water security and climate events, leading to mixed models of routine and reactive vaccination. Health systems emphasize data-driven targeting, pharmacy-enabled access in urban areas, and mobile teams for remote communities. Cross-border collaboration and consistent supply visibility reinforce readiness during seasonal peaks.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Cholera Vaccine Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers :
- Rising Incidence of Cholera Outbreaks
- Increased Awareness and Advocacy
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New Vaccine Approvals and Increased Production Capacity - The Global Cholera Vaccine Market is witnessing notable developments with new vaccine approvals and increased production capacity, reflecting a concerted effort to address the ongoing challenge of cholera prevention and control. Recent approvals of cholera vaccines by regulatory authorities signal a growing recognition of the importance of vaccination in combating cholera outbreaks and reducing disease burden. These approvals expand the range of available vaccine options, providing healthcare providers and public health authorities with more tools to implement effective vaccination strategies in endemic regions and during humanitarian crises.
Moreover, the scaling up of production capacity for cholera vaccines is a significant milestone in strengthening global immunization efforts against cholera. Increased production capacity enables vaccine manufacturers to meet growing demand, support mass vaccination campaigns, and respond rapidly to cholera outbreaks. This expansion of manufacturing capabilities enhances vaccine accessibility and affordability, particularly in resource-limited settings where cholera burden is high. Additionally, investments in production infrastructure and technology contribute to improving vaccine quality, stability, and supply chain efficiency, further bolstering the global response to cholera outbreaks and advancing progress towards cholera elimination goals.
Restraints :
- Limited Vaccine Stockpile and Supply Shortages
- High Costs and Unequal Distribution
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Hesitancy and Lack of Awareness - Despite the significant strides made in cholera vaccine development and deployment, the Global Cholera Vaccine Market faces challenges stemming from vaccine hesitancy and lack of awareness. Vaccine hesitancy, fueled by misinformation, mistrust, and cultural beliefs, poses a barrier to vaccine acceptance and uptake, particularly in communities affected by cholera outbreaks. Misconceptions about vaccine safety, efficacy, and side effects can undermine confidence in cholera vaccines, leading to suboptimal vaccination coverage and heightened vulnerability to cholera transmission. Addressing vaccine hesitancy requires targeted communication strategies, community engagement initiatives, and collaboration with local leaders and influencers to dispel myths, build trust, and promote the benefits of vaccination.
Furthermore, a lack of awareness about cholera and the importance of vaccination exacerbates the challenge of controlling cholera outbreaks and achieving optimal vaccine coverage. Many individuals in high-risk areas may not be familiar with the signs, symptoms, and preventive measures for cholera, leading to delayed recognition of outbreaks and inadequate uptake of vaccination services. Enhancing public awareness through education campaigns, community outreach, and healthcare provider training is essential for promoting early detection, prompt treatment, and proactive vaccination strategies. By addressing vaccine hesitancy and increasing awareness about cholera and vaccination, stakeholders can overcome barriers to vaccine uptake and strengthen efforts to prevent and control cholera on a global scale.
Opportunity :
- Technological Advancements
- Focus on Preventive Strategies
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Collaboration Between Stakeholders - Collaboration between stakeholders is paramount in driving advancements and ensuring widespread accessibility to cholera vaccines across the Global Cholera Vaccine Market. Governments, pharmaceutical companies, non-governmental organizations (NGOs), research institutions, and international agencies must collaborate closely to address the multifaceted challenges associated with cholera prevention and control. Through strategic partnerships, stakeholders can leverage their respective expertise, resources, and networks to accelerate vaccine research and development, enhance vaccine production capacity, and facilitate equitable distribution of vaccines to vulnerable populations.
Furthermore, collaboration fosters information sharing, capacity building, and coordinated efforts to strengthen vaccination campaigns, surveillance systems, and outbreak response mechanisms. By working together, stakeholders can overcome barriers such as vaccine supply shortages, logistical challenges, and vaccine hesitancy, ultimately contributing to the reduction of cholera morbidity and mortality worldwide. Moreover, collaborative initiatives can empower communities with knowledge about cholera prevention, improve access to clean water and sanitation infrastructure, and promote sustainable public health interventions. As stakeholders continue to collaborate effectively, the Global Cholera Vaccine Market can achieve its goal of eliminating cholera as a public health threat, safeguarding the health and well-being of populations globally.
Cholera Vaccines Market Competitive Landscape Analysis
Cholera Vaccines Market demonstrates a highly competitive environment shaped by leading pharmaceutical players focusing on innovation, strategic collaboration, and targeted expansion. Companies are enhancing production capabilities and strengthening partnerships with research institutions to deliver advanced formulations. The market’s competitive intensity is amplified by increased investment in growth-oriented strategies and long-term distribution networks.
Market Structure and Concentration
Dominated by a few major manufacturers, the sector exhibits moderate to high concentration with specialized biotech firms entering through niche product lines. Strategic merger activities and alliances have created integrated supply chains. The strong presence of established players intensifies competition while encouraging smaller companies to differentiate through targeted innovation and enhanced manufacturing strategies.
Brand and Channel Strategies
Prominent companies employ robust brand positioning supported by extensive outreach to healthcare providers and government programs. Emphasis is placed on strengthening distribution channels across emerging regions while building reliable partnerships with local suppliers. Competitive strategies also focus on reinforcing vaccine awareness and trust among key medical communities to sustain growth.
Innovation Drivers and Technological Advancements
Continuous technological advancements in vaccine delivery methods and manufacturing efficiency fuel strong differentiation. Firms invest in novel formulations with enhanced stability and efficacy, strengthening their innovation pipeline. Collaborative research and development agreements accelerate new product approvals, while digital solutions improve monitoring, boosting competitive advantage and expansion potential.
Regional Momentum and Expansion
Emerging economies are witnessing strong expansion driven by increasing immunization programs and improved healthcare infrastructure. Strategic partnerships with public health agencies help strengthen local presence and accelerate market growth. Leading players adopt region-specific strategies to navigate regulatory pathways and ensure efficient vaccine deployment across high-demand geographies.
Future Outlook
With evolving demand patterns and technological breakthroughs, the market’s future outlook remains robust. Companies are expected to intensify collaboration for research and distribution while pursuing diversified expansion plans. Enhanced manufacturing resilience and digital integration will further refine strategies, solidifying competitive positioning and sustaining long-term growth.
Key players in Cholera Vaccine Market include
- ThyssenKrupp Airport Systems (ThyssenKrupp AG)
- CIMC (CIMC-Tianda / CIMC Group Ltd.)
- JBT Corporation
- ShinMaywa Industries, Ltd.
- Adelte Group
- Vataple Group Ltd.
- FMT Airport Gate Support Systems AB
- Hubner GmbH & Co. KG
- Airport Equipment Ltd.
- Ameribridge, Inc.
- PT Bukaka Teknik Utama
- A.D. McCallum & Son Pty Ltd.
- MHI-TES (Mitsubishi Heavy Industries – Terminal Equipment Systems)
- Deerns (Engineering / airport systems integrator)
- Hüttenes-Albertus (if applicable) / other regional specialists
In this report, the profile of each market player provides following information:
- Market Share Analysis
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Route of Administration
- Market Snapshot, By End Users
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Region
- Cholera Vaccine Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Rising Incidence of Cholera Outbreaks
- Increased Awareness and Advocacy
- New Vaccine Approvals and Increased Production Capacity
- Restraints
- Limited Vaccine Stockpile and Supply Shortages
- High Costs and Unequal Distribution
- Hesitancy and Lack of Awareness
- Opportunities
- Technological Advancements
- Focus on Preventive Strategies
- Collaboration Between Stakeholders
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
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Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Cholera Vaccines Market, By Type, 2021 - 2031 (USD Million)
- Dukoral
- Shanchol
- Euvichol
- Cholera Vaccines Market, By Route of Administration, 2021 - 2031 (USD Million)
- Oral
- Cholera Vaccines Market, By End Users, 2021 - 2031 (USD Million)
- Hospitals
- Homecare
- Specialty Clinics
- Others
- Cholera Vaccines Market, By Distribution Channel, 2021 - 2031 (USD Million)
- Hospital Pharmacy
- Online Pharmacy
- Retail Pharmacy
- Cholera Vaccine Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Cholera Vaccines Market, By Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- ThyssenKrupp Airport Systems (ThyssenKrupp AG)
- CIMC (CIMC-Tianda / CIMC Group Ltd.)
- JBT Corporation
- ShinMaywa Industries, Ltd.
- Adelte Group
- Vataple Group Ltd.
- FMT Airport Gate Support Systems AB
- Hubner GmbH & Co. KG
- Airport Equipment Ltd.
- Ameribridge, Inc.
- PT Bukaka Teknik Utama
- A.D. McCallum & Son Pty Ltd.
- MHI-TES (Mitsubishi Heavy Industries – Terminal Equipment Systems)
- Deerns (Engineering / airport systems integrator)
- Hüttenes-Albertus (if applicable) / other regional specialists
- Company Profiles
- Analyst Views
- Future Outlook of the Market

