Cancer Pain Therapeutics Market
By Drug Type;
Opioids, Non-opioids, Adjuvant Analgesics and Topical AgentsBy Drug Class;
Opioid Analgesics, NSAIDs, Antidepressants, Anticonvulsants and Local AnestheticsBy Route of Administration;
Oral, Injectable, Topical and TransdermalBy Indication;
Bone Pain, Neuropathic Pain, Visceral Pain and Somatic PainBy End-user;
Hospitals, Home Care Settings, Specialty Clinics and Nursing HomesBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa and Latin America - Report Timeline (2021 - 2031)Cancer Pain Therapeutics Market Overview
Cancer Pain Therapeutics Market (USD Million)
Cancer Pain Therapeutics Market was valued at USD 7,991.53 million in the year 2024. The size of this market is expected to increase to USD 11,677.66 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 5.6%.
Cancer Pain Therapeutics Market
*Market size in USD million
CAGR 5.6 %
| Study Period | 2025 - 2031 | 
|---|---|
| Base Year | 2024 | 
| CAGR (%) | 5.6 % | 
| Market Size (2024) | USD 7,991.53 Million | 
| Market Size (2031) | USD 11,677.66 Million | 
| Market Concentration | Medium | 
| Report Pages | 328 | 
Major Players
- Purdue Pharma
 - Teva Pharmaceutical Industries Ltd.
 - Johnson & Johnson
 - Novartis AG
 - Pfizer Inc.
 - Eli Lilly and Company
 - Abbott Laboratories
 - Mallinckrodt Pharmaceuticals
 - Endo Pharmaceuticals
 - GlaxoSmithKline PLC
 
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Cancer Pain Therapeutics Market
Fragmented - Highly competitive market without dominant players
The cancer pain therapeutics market is experiencing significant growth, driven by the increasing prevalence of cancer and the associated need for effective pain management. Studies indicate that approximately 66% of patients with advanced cancer experience pain, highlighting the critical need for effective pain management solutions. This growing demand is further fueled by an aging population and the rising number of cancer survivors requiring long-term pain relief.
Innovations in Pain Management Therapies
Advancements in medical research have led to the development of innovative therapies for managing cancer-related pain. These include novel drug formulations, targeted therapies, and multimodal approaches that aim to enhance efficacy while minimizing side effects. Notably, combination drug therapies have been shown to provide better pain relief with minimal side effects compared to single drugs. These innovations are contributing to the market's growth and improving patient outcomes.
Emphasis on Quality of Life
Healthcare professionals are increasingly recognizing the importance of pain management in improving the quality of life for cancer patients. Effective pain control can lead to significant improvements in patient outcomes, with studies suggesting up to a 40% enhancement in quality of life. This emphasis on patient-centric care is driving the adoption of personalized treatment plans that address the unique needs of each patient.
Future Outlook and Market Potential
As the healthcare industry continues to prioritize personalized medicine and patient-centric care, the outlook for advancements in cancer pain therapeutics remains promising. Ongoing clinical research, increasing healthcare investments, and strategic industry collaborations are creating a fertile landscape for innovation. The market is expected to grow steadily in the coming years, driven by the continued emphasis on enhancing treatment outcomes and patient comfort.
Cancer Pain Therapeutics Market Key Takeaways
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The cancer pain therapeutics market is expanding due to increasing cancer prevalence, rising patient awareness of pain management, and the growing need for targeted pain relief solutions.
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Advancements in opioid and non-opioid analgesics, including novel drug formulations and controlled-release therapies, are enhancing treatment effectiveness and patient compliance.
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Growing use of adjuvant therapies such as antidepressants, anticonvulsants, and local anesthetics is improving outcomes for patients with neuropathic pain related to cancer.
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Rising adoption of palliative care services and increasing integration of multimodal pain management approaches are positively impacting overall patient quality of life.
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Emerging biologic and gene-based therapies are being explored to offer non-addictive, long-term pain control and to reduce dependency on traditional opioid treatments.
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North America and Europe lead the market due to strong healthcare infrastructure, widespread oncology treatment accessibility, and active R&D initiatives.
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Key pharmaceutical companies are focusing on drug innovation, strategic partnerships, and regulatory approvals to expand their oncology pain management portfolios.
 
Cancer Pain Therapeutics Market Recent Developments
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In 2023, the U.S. Food and Drug Administration (FDA) approved an extended-release formulation of buprenorphine for cancer patients with chronic pain. This long-acting option aims to provide consistent pain relief with fewer doses, enhancing patient compliance and overall quality of life.
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In January 2025, Dogwood Therapeutics initiated dosing in its Phase 2b HALT-CINP clinical trial to evaluate Halneuron for chemotherapy-induced neuropathic pain (CINP). This development follows the Fast Track designation granted by the FDA in August 2024, highlighting the need for advanced CINP treatment options.
 
Cancer Pain Therapeutics Market Segment Analysis
In this report, the Cancer Pain Therapeutics Market has been segmented by Drug Type, Drug Class, Route of Administration, Indication, End-user and Geography. These dimensions highlight evolving clinical preferences, access-driven care models, and emerging strategies to improve patient quality of life. Market dynamics are shaped by unmet needs in late-stage cancer pain, innovations in non-opioid solutions, and supportive care policies enabling better coverage and treatment continuity.
Cancer Pain Therapeutics Market, Segmentation by Drug Type
The Drug Type segmentation underscores a shift from conventional opioid reliance to broader multimodal pain management strategies. Therapy choice depends on cancer severity, comorbidities, and optimization of side-effect profiles. Stakeholders focus on improving accessibility, minimizing addiction risk, and accelerating approvals of innovative supportive care therapeutics.
Opioids
Opioids remain central to managing moderate to severe cancer pain by modulating central nervous system responses. Their strong efficacy sustains high adoption, particularly in advanced cancers where other interventions fall short. Growth depends on balancing effective relief with regulations, abuse deterrence, and patient education on safe usage.
Non-opioids
Non-opioid drugs have gained importance due to rising concerns over opioid dependency and adverse effects. These therapies offer supportive analgesia with improved tolerability and are increasingly paired in combination regimens to optimize outcomes. Investments target formulations that reduce gastrointestinal impact and enhance patient compliance.
Adjuvant Analgesics
Adjuvants support targeted pain relief in neuropathic and complex pain scenarios where standard analgesics may fail. Their role expands as physicians push for personalized care tailored to tumor location and pain mechanisms. Market growth relies on education campaigns and clinical guideline inclusion strengthening prescriber confidence.
Topical Agents
Topicals provide localized relief with minimized systemic exposure, important for patients experiencing medication-related toxicity. Demand rises in palliative care centers where simpler administration and comfort are prioritized. Focus areas include novel delivery formats improving dermal penetration and patient comfort.
Cancer Pain Therapeutics Market, Segmentation by Drug Class
Segmentation by Drug Class reflects clinical decision pathways based on pain intensity and progression. Manufacturers strive to refine formulations with improved safety, fewer interactions, and sustained therapeutic efficacy. Adoption trends align strongly with evolving oncology treatment protocols and supportive care reimbursement.
Opioid Analgesics
Opioid analgesics—including morphine and fentanyl—remain essential tools for strong and breakthrough pain. Their future success depends on abuse-deterrent technologies, optimized dosing, and patch-based delivery that eases administration burdens. Investment aligns with strategies that expand access in underserved regions.
NSAIDs
NSAIDs are often first-line for mild-to-moderate pain and inflammatory tumor responses, minimizing opioid initiation. Drug developers concentrate on improved GI safety and reduced renal complications to maintain long-term use. Regional demand benefits from broad affordability and OTC availability in select markets.
Antidepressants
Antidepressants help alleviate neuropathic pain linked with chemotherapy and metastasis by modulating nerve signaling. Awareness grows around supportive mental health benefits in cancer survivors. Market opportunity stems from dual-action coverage improving overall treatment experience.
Anticonvulsants
Anticonvulsants reduce aberrant neural firing driving neuropathic pain common in progressive cancers. Physicians adopt them to complement systemic analgesics and boost symptom control. Continued clinical validation enhances confidence and expands portfolio treatment indications.
Local Anesthetics
Local anesthetics deliver targeted numbing at procedure or tumor-affected sites, reducing opioid reliance. Demand expands across interventional oncology and palliative surgeries. Growth focuses on long-acting options that maintain analgesia without frequent re-administration.
Cancer Pain Therapeutics Market, Segmentation by Route of Administration
The Route of Administration selection balances onset speed, patient comfort, and continuity of care. Innovation centers on extended-release delivery, transdermal absorption, and self-administered formats that lower clinical workload. Improved access drives global adoption to mitigate suffering and improve daily functioning.
Oral
Oral drugs remain preferred for ease of self-administration and affordability across outpatient oncology settings. Manufacturers enhance bioavailability and tolerability to support long-term treatment. Growth reflects supportive insurance policies and the trend toward home-based care.
Injectable
Injectables deliver rapid relief for severe and acute cancer pain, especially in hospitals and advanced cases. Improvements in infusion systems and nerve block techniques broaden usage across palliative pathways. Providers prioritize training to ensure safe administration and stronger clinical oversight.
Topical
Topical administration suits localized tumor pain and reduces drug burden on major organs. Growth is strongest among patients requiring targeted support with minimal systemic complications. Expansion relies on better skin-penetration technologies and supportive clinical data.
Transdermal
Transdermal patches provide steady plasma drug levels and improved compliance for chronic pain conditions. Preference grows in patients with swallowing difficulties or GI intolerance. Market differentiation focuses on advanced adhesives and tamper-resistant packaging.
Cancer Pain Therapeutics Market, Segmentation by Indication
Different cancer pain types require targeted mechanism-based solutions addressing nerve injury, organ pressure, or bone metastases. Rising adoption of multimodal analgesia aims to improve relief while curbing opioid dependence. Tailored treatment protocols support value-based oncology care.
Bone Pain
Bone metastasis causes highly debilitating nociceptive pain demanding strong analgesics and adjunct therapies. Uptake is influenced by oncology guidelines, radiotherapy alignment, and partnership with orthopedic specialists. Therapy optimization reduces fractures and enhances mobility.
Neuropathic Pain
Neuropathic pain arises from nerve compression or chemotherapy toxicity, requiring adjuvant classes for effective relief. Physician focus centers on reducing hypersensitivity and improving sleep quality in patients. This segment expands with greater awareness of complex pain pathways.
Visceral Pain
Visceral pain linked to organ involvement demands a layered multimodal approach to stabilize comfort. Uptake grows alongside improved diagnostics and timely palliative intervention. Integration with interventional oncology enhances symptom control.
Somatic Pain
Somatic pain associated with tissue injury or tumor progression relies on both standard analgesics and localized therapies. Hospitals emphasize accurate assessment tools for quantifying pain intensity. Strong alignment with supportive care improves recovery and well-being.
Cancer Pain Therapeutics Market, Segmentation by End-user
The End-user segmentation reflects care delivery models that determine access to timely pain therapy. Hospitals dominate due to advanced oncology, however home-care solutions rise to improve continuity and lower treatment burden. Stakeholders prioritize efficient coordination across multidisciplinary teams.
Hospitals
Hospitals lead in adoption with comprehensive oncology infrastructure, enabling rapid management of breakthrough pain. Growth depends on integration with palliative services, reimbursement, and novel interventional programs. Training ensures safe administration of strong analgesics under clinical monitoring.
Home Care Settings
Home care supports patients desiring comfortable recovery environments with reduced hospital dependency. Growth accelerates due to advanced oral and transdermal formulations that simplify therapy. Partnerships between payers and providers reinforce adherence and care continuity.
Specialty Clinics
Specialty clinics focus on multidisciplinary pain evaluation and tailored treatment pathways. Their role strengthens through patient education and advanced procedures designed to minimize discomfort. Regional expansion aligns with improved referral systems and oncology collaboration.
Nursing Homes
Nursing homes manage long-term cancer survivors and late-stage patients who need regular pain monitoring. Adoption hinges on accessible supply chains and caregiver training. Vendors target user-friendly formats that minimize complexity while safeguarding quality of life.
Cancer Pain Therapeutics Market, Segmentation by Geography
In this report, the Cancer Pain Therapeutics Market has been segmented by Geography into five regions: North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
North America
North America dominates due to strong cancer care infrastructure, reimbursement support, and availability of advanced pain drugs. Physicians adopt multimodal pain strategies driven by opioid stewardship initiatives. Market penetration remains highest where awareness and supportive care pathways ensure continuous access.
Europe
Europe emphasizes clinical risk management and regulatory oversight fostering adoption of safer analgesic alternatives. Integration of palliative care into national frameworks boosts consistency in treatment. Partnerships with patient advocacy groups raise awareness and accessibility across regions.
Asia Pacific
Asia Pacific exhibits rapid expansion as oncology capacity increases and public health policies encourage access to essential pain medicines. Local manufacturing enhances affordability, supporting greater treatment reach. Cultural shifts and education campaigns strengthen acceptance of palliative care.
Middle East & Africa
Middle East & Africa progress depends on investments in oncology infrastructure and improved procurement of essential drugs. International partnerships expand distribution, while training reduces under-treatment of cancer pain. Addressing affordability remains a key challenge.
Latin America
Latin America advances with stronger policy frameworks to ensure equitable access and standardized pain management. Expansion of specialty oncology centers boosts availability of advanced therapies. Collaborative efforts with NGOs enhance awareness and continuum of care.
Cancer Pain Therapeutics Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Cancer Pain Therapeutics Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Comprehensive Market Impact Matrix
This matrix outlines how core market forces—Drivers, Restraints, and Opportunities—affect key business dimensions including Growth, Competition, Customer Behavior, Regulation, and Innovation.
| Market Forces ↓ / Impact Areas → | Market Growth Rate | Competitive Landscape | Customer Behavior | Regulatory Influence | Innovation Potential | 
|---|---|---|---|---|---|
| Drivers | High impact (e.g., tech adoption, rising demand) | Encourages new entrants and fosters expansion | Increases usage and enhances demand elasticity | Often aligns with progressive policy trends | Fuels R&D initiatives and product development | 
| Restraints | Slows growth (e.g., high costs, supply chain issues) | Raises entry barriers and may drive market consolidation | Deters consumption due to friction or low awareness | Introduces compliance hurdles and regulatory risks | Limits innovation appetite and risk tolerance | 
| Opportunities | Unlocks new segments or untapped geographies | Creates white space for innovation and M&A | Opens new use cases and shifts consumer preferences | Policy shifts may offer strategic advantages | Sparks disruptive innovation and strategic alliances | 
Drivers, Restraints and Opportunity Analysis
Drivers
- Rising cancer incidence and prevalence
 - Growing demand for effective pain management
 - Advancements in opioid and non-opioid therapies
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Increasing palliative care and oncology services - Expansion of palliative care and oncology services is emerging as a key driver in the growth of the cancer pain therapeutics market. As healthcare systems increasingly prioritize not only survival but also the comfort of cancer patients, there is a rising demand for effective pain management solutions. Medical institutions are embedding comprehensive pain control strategies within oncology treatment plans, recognizing the importance of quality of life during and after cancer therapy. This has led to a greater reliance on specialized therapeutics designed to alleviate cancer-related pain.
In both developed and developing regions, growing investments in supportive and palliative care infrastructure are expanding access to pain management services. Patients undergoing longer and more intensive treatment regimens are more likely to require consistent relief from cancer-induced pain. This trend is fueling the increased use of opioids, adjuvants, and advanced non-opioid analgesics tailored for oncology patients. As awareness rises around the importance of comfort-focused care, the adoption of cancer pain therapeutics is expected to accelerate, supporting sustained market growth.
 
Restraints
- Strict regulations on opioid prescriptions
 - Risk of drug dependency and side effects
 - Limited access in low-income cancer care settings
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High cost of advanced therapeutics - High treatment costs associated with advanced cancer pain therapeutics remain a major limitation for market growth. Modern pain management options, including targeted biologics, sustained-release opioids, and specialized drug delivery systems, offer improved outcomes but are often priced beyond the reach of many patients. This is particularly challenging in regions with limited healthcare funding or where insurance coverage is inadequate, placing a significant financial burden on individuals and families.
The elevated cost of these therapies can result in reduced accessibility, delayed initiation of treatment, or poor adherence over time. Even in high-income countries, restrictive reimbursement frameworks and budgetary constraints can limit patient access to newer, more effective solutions. These economic barriers not only hinder the widespread adoption of advanced therapeutics but also impact overall patient well-being, making cost a persistent obstacle in delivering equitable cancer pain management globally.
 
Opportunities
- Development of targeted pain relief drugs
 - Innovation in non-opioid pain management solutions
 - Expansion of cancer care in emerging markets
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Increased funding for pain therapy research - A significant opportunities in the cancer pain therapeutics market. Public health agencies, research institutions, and private pharmaceutical companies are allocating more resources toward understanding the mechanisms of cancer-related pain and developing innovative treatments. This heightened investment is driving the discovery of novel analgesic compounds, non-opioid alternatives, and advanced delivery technologies that can offer safer and more effective pain relief options.
Pharmaceutical companies are also capitalizing on this momentum by partnering with academic research centers and biotech firms to co-develop and commercialize promising therapies. These collaborations not only facilitate technological innovation but also help navigate regulatory pathways more efficiently. As new therapies enter clinical trials and receive approvals, the market is expected to benefit from a broader array of targeted and patient-specific solutions.
The rising trend of dedicated funding and strategic investment is set to enhance the global availability of cancer pain therapeutics. With greater financial support fueling R&D advancements and faster market entry, the overall competitiveness and accessibility of pain management solutions will likely improve, driving long-term market growth.
 
Cancer Pain Therapeutics Market Competitive Landscape Analysis
Cancer Pain Therapeutics Market is defined by competition among pharmaceutical companies, biotech firms, and healthcare distributors. Companies adopt strategies such as mergers, partnerships, and collaboration to enhance efficacy, safety, and patient adherence. With nearly 60% of share concentrated among leading players, continuous innovation in opioid formulations, non-opioid analgesics, and combination therapies drives steady growth across hospitals, oncology centers, and palliative care facilities.
Market Structure and Concentration
The industry demonstrates moderate concentration, with about 55% of revenues controlled by multinational pharmaceutical manufacturers. Regional players contribute to expansion through specialized formulations and cost-effective treatment options. This combination of consolidated leadership and fragmented innovation shapes competitive strategies, ensuring consistent growth in cancer pain therapeutics.
Brand and Channel Strategies
Leading firms strengthen their brands through partnerships with hospitals, collaborations with oncology centers, and direct contracts with healthcare providers. Nearly 60% of adoption occurs via hospital pharmacies and specialized distributors, while online pharmacies and clinical networks support channel expansion. Effective strategies emphasize efficacy, safety, and patient compliance, reinforcing sustainable growth in the market.
Innovation Drivers and Technological Advancements
Ongoing innovation focuses on novel opioid formulations, sustained-release delivery systems, and combination analgesics. Around 45% of R&D investments target technological advancements that improve pain management, minimize side effects, and enhance patient adherence. Strategic collaboration between manufacturers and healthcare providers drives strategies, enabling measurable growth in cancer pain therapeutics.
Regional Momentum and Expansion
North America accounts for nearly 40% of demand, driven by advanced oncology care and palliative treatment adoption. Europe demonstrates steady growth with hospital and clinic integration, while Asia-Pacific shows rapid expansion surpassing 25% due to increasing cancer prevalence, healthcare infrastructure, and awareness. Regional strategies enhance market penetration and competitive positioning.
Future Outlook
The market is projected to sustain robust growth as demand for effective, safe, and patient-centric cancer pain therapeutics rises. Stronger partnerships and mergers will reshape competitive landscapes, while continuous innovation ensures improved efficacy, safety, and patient outcomes. The future outlook highlights broad expansion supported by oncology treatment growth, technological advancements, and clinical adoption.
Key players in Cancer Pain Therapeutics Market include :
- Johnson & Johnson (Janssen)
 - Purdue Pharma
 - Teva Pharmaceutical Industries Ltd.
 - Endo International plc
 - Pfizer Inc.
 - Novartis AG
 - Roche Holding AG
 - AstraZeneca plc
 - Grünenthal GmbH
 - Mallinckrodt Pharmaceuticals
 - Sun Pharmaceutical Industries Ltd.
 - DaVita Inc.
 - Gilead Sciences, Inc.
 - Allergan (AbbVie)
 - Baxter International Inc.
 
In this report, the profile of each market player provides following information:
- Market Share Analysis
 - Company Overview and Product Portfolio
 - Key Developments
 - Financial Overview
 - Strategies
 - Company SWOT Analysis
 
- Introduction 
- Research Objectives and Assumptions
 - Research Methodology
 - Abbreviations
 
 - Market Definition & Study Scope
 - Executive Summary 
- Market Snapshot, By Drug
 - Market Snapshot, By Drug Class
 - Market Snapshot, By Route of Administration
 - Market Snapshot, By Indication
 - Market Snapshot, By End-User
 - Market Snapshot, By Region
 
 - Cancer Pain Therapeutics Market Dynamics 
- Drivers, Restraints and Opportunities 
- Drivers 
- Rising cancer incidence and prevalence
 - Growing demand for effective pain management
 - Advancements in opioid and non-opioid therapies
 - Increasing palliative care and oncology services
 
 - Restraints Opportunities 
- Strict regulations on opioid prescriptions
 - Risk of drug dependency and side effects
 - Limited access in low-income cancer care settings
 - High cost of advanced therapeutics
 - Development of targeted pain relief drugs
 - Innovation in non-opioid pain management solutions
 - Expansion of cancer care in emerging markets
 - Increased funding for pain therapy research
 
 
 - Drivers 
 - PEST Analysis 
- Political Analysis
 - Economic Analysis
 - Social Analysis
 - Technological Analysis
 
 - Porter's Analysis 
- Bargaining Power of Suppliers
 - Bargaining Power of Buyers
 - Threat of Substitutes
 - Threat of New Entrants
 - Competitive Rivalry
 
 
 - Drivers, Restraints and Opportunities 
 - Market Segmentation 
- Cancer Pain Therapeutics Market, By Drug Type, 2021 - 2031 (USD Million) 
- Opioids
 - Non-opioids
 - Adjuvant Analgesics
 - Topical Agents
 
 - Cancer Pain Therapeutics Market, By Drug Class, 2021 - 2031 (USD Million) 
- Opioid Analgesics
 - NSAIDs
 - Antidepressants
 - Anticonvulsants
 - Local Anesthetics
 
 - Cancer Pain Therapeutics Market, By Route of Administration, 2021 - 2031 (USD Million) 
- Oral
 - Injectable
 - Topical
 - Transdermal
 
 - Cancer Pain Therapeutics Market, By Indication, 2021 - 2031 (USD Million) 
- Bone Pain
 - Neuropathic Pain
 - Visceral Pain
 - Somatic Pain
 
 - Cancer Pain Therapeutics Market, By End-user, 2021 - 2031 (USD Million) 
- Hospitals
 - Home Care Settings
 - Specialty Clinics
 - Nursing Homes
 
 - Cancer Pain Therapeutics Market, By Geography, 2021 - 2031 (USD Million) 
- North America 
- United States
 - Canada
 
 - Europe 
- Germany
 - United Kingdom
 - France
 - Italy
 - Spain
 - Nordic
 - Benelux
 - Rest of Europe
 
 - Asia Pacific 
- Japan
 - China
 - India
 - Australia & New Zealand
 - South Korea
 - ASEAN (Association of South East Asian Countries)
 - Rest of Asia Pacific
 
 - Middle East & Africa 
- GCC
 - Israel
 - South Africa
 - Rest of Middle East & Africa
 
 - Latin America 
- Brazil
 - Mexico
 - Argentina
 - Rest of Latin America
 
 
 - North America 
 
 - Cancer Pain Therapeutics Market, By Drug Type, 2021 - 2031 (USD Million) 
 - Competitive Landscape 
- Company Profiles 
- Johnson & Johnson (Janssen)
 - Purdue Pharma
 - Teva Pharmaceutical Industries Ltd.
 - Endo International plc
 - Pfizer Inc.
 - Novartis AG
 - Roche Holding AG
 - AstraZeneca plc
 - Grünenthal GmbH
 - Mallinckrodt Pharmaceuticals
 - Sun Pharmaceutical Industries Ltd.
 - DaVita Inc.
 - Gilead Sciences, Inc.
 - Allergan (AbbVie)
 - Baxter International Inc.
 
 
 - Company Profiles 
 - Analyst Views
 - Future Outlook of the Market
 

