Global Short Bowel Syndrome Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Drug Class;
Glucagon-Like Peptide-2 (GLP-2) , Growth Hormone, Glutamine, and Others.By Distribution Channel;
Hospital Pharmacies and Online & Retail Pharmacies.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa, and Latin America - Report Timeline (2021 - 2031).Introduction
Global Short Bowel Syndrome Market (USD Million), 2021 - 2031
In the year 2024, the Global Short Bowel Syndrome Market was valued at USD 937.69 million. The size of this market is expected to increase to USD 2,138.59 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 12.5%.
Short bowel syndrome (SBS) is a complex and debilitating gastrointestinal disorder characterized by the inadequate absorption of nutrients and fluids due to the surgical removal or dysfunction of a significant portion of the small intestine. This condition can result from various underlying causes, including surgical resection due to trauma, Crohn's disease, ischemic injury, or congenital defects. Individuals with SBS often experience symptoms such as severe diarrhea, malnutrition, electrolyte imbalances, and weight loss, significantly impacting their quality of life and requiring ongoing medical management. The global short bowel syndrome market addresses the diverse needs of patients with this challenging condition, encompassing a range of therapeutic approaches aimed at improving nutritional absorption, managing symptoms, and enhancing overall well-being.
The market for short bowel syndrome is driven by a combination of factors, including advancements in medical technology, increasing prevalence of gastrointestinal disorders, and growing awareness among healthcare professionals and patients. Technological innovations in the development of novel treatments and medical devices play a crucial role in improving the management of SBS, offering patients more effective and personalized therapeutic options. Additionally, the rising incidence of gastrointestinal diseases, such as Crohn's disease and intestinal ischemia, contributes to the expanding patient population with SBS, driving the demand for innovative treatment solutions.
Furthermore, the global short bowel syndrome market is characterized by a diverse range of therapeutic interventions, including pharmacological treatments, nutritional support, and surgical procedures, tailored to address the unique needs of individual patients. Pharmacological therapies aim to reduce diarrhea, promote intestinal adaptation, and enhance nutrient absorption, while nutritional support plays a fundamental role in providing essential nutrients and maintaining hydration. Surgical interventions, such as intestinal lengthening procedures or small bowel transplantation, may be considered for select patients with severe SBS refractory to conservative treatments. The market's emphasis on comprehensive and multidisciplinary approaches underscores the collaborative efforts of healthcare providers, researchers, and industry stakeholders in addressing the complex challenges posed by short bowel syndrome and improving outcomes for affected individuals.
Global Short Bowel Syndrome Market Recent Developments
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In October 2022, VectivBio Holding AG released positive interim data from the company's ongoing Phase 2 study evaluating the safety, pharmacokinetics, and efficacy of apraglutide, a GLP-2 agonist, in adult patients with Short Bowel Syndrome.
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In June 2022, National Institute for Health and Care Excellence (NICE), the health technology appraisal body in England and Wales recommended the use of Takeda's Revestive (teduglutide) once daily subcutaneous injection as an option for people living with Short Bowel Syndrome (SBS) aged 1 year and above
Segment Analysis
The global short bowel syndrome (SBS) market is segmented by drug class into intestinal growth factors, parenteral nutrition (PN), and other supportive therapies. Intestinal growth factors, such as teduglutide, are designed to stimulate the growth of the remaining intestine, improving nutrient absorption and reducing the dependency on parenteral nutrition. Parenteral nutrition is a critical drug class for SBS patients, providing necessary nutrients through intravenous feeding when oral intake or absorption is insufficient. Other supportive therapies include medications to manage symptoms like diarrhea, pain, or infection, as well as drugs to promote gut motility and nutrient absorption. As treatment options advance, biologics and novel therapies are expected to improve patient outcomes and reduce reliance on long-term nutritional support.
The distribution channel segment includes hospitals, specialty clinics, and retail pharmacies. Hospitals are the largest distribution channel for SBS treatments, as patients with severe forms of the condition often require inpatient care, intensive monitoring, and specialized therapies like parenteral nutrition. Specialty clinics, particularly those focused on gastroenterology or nutrition, are key for ongoing management, especially for patients who need regular follow-ups and adjustments to their treatment regimen. Retail pharmacies are also important for dispensing oral medications and providing access to home-based therapies, especially as the management of SBS increasingly shifts to outpatient care with more at-home treatment options. Online pharmacies are emerging as a growing distribution channel, offering convenience for patients to receive medications or nutritional supplies.
Geographically, North America holds the largest market share for SBS treatment, driven by advanced healthcare infrastructure, high awareness of the disease, and widespread access to specialized therapies such as parenteral nutrition and growth factor treatments. Europe also represents a significant portion of the market, with a robust healthcare system and increasing focus on improving quality of life for SBS patients through advanced therapeutic approaches. The Asia-Pacific region is anticipated to experience rapid growth due to rising healthcare expenditure, an increasing prevalence of gastrointestinal diseases, and expanding access to modern therapies. As awareness of SBS improves in developing countries and healthcare systems evolve, the demand for effective treatments and management solutions is expected to rise in this region.
Global Short Bowel Syndrome Segment Analysis
In this report, the Global Short Bowel Syndrome Market has been segmented by Drug Class, Distribution Channel and Geography.
Global Short Bowel Syndrome Market, Segmentation by Drug Class
The Global Short Bowel Syndrome Market has been segmented by Drug Class into Glucagon-like Peptide-2 (GLP-2), Growth Hormone, Glutamine and Others.
The anticipated growth of the global short bowel syndrome market from 2024 to 2030 is driven by a combination of factors, including advancements in therapeutic options and an increasing prevalence of gastrointestinal disorders. These advancements in therapeutic options, segmented by drug class such as glucagon-like peptide-2 (GLP-2), growth hormone, glutamine, and others, offer diverse mechanisms of action to address the multifaceted nature of short bowel syndrome. By targeting specific aspects of the condition's pathophysiology, such as promoting intestinal adaptation and enhancing nutrient absorption, these drugs aim to alleviate symptoms and improve the quality of life for patients with short bowel syndrome.
Moreover, the growing awareness among healthcare providers and patients about short bowel syndrome is expected to contribute to market growth. With increased recognition of the condition's impact on patients' lives and the availability of innovative treatment options, there is a heightened focus on early diagnosis and comprehensive management strategies. As research and development efforts continue to yield novel therapies and therapeutic approaches, the global short bowel syndrome market is poised to expand, offering new hope and improved outcomes for individuals affected by this challenging gastrointestinal disorder.
Global Short Bowel Syndrome Market, Segmentation by Distribution Channel
The Global Short Bowel Syndrome Market has been segmented by Distribution Channel into Hospital Pharmacies and Online & Retail Pharmacies.
The global short bowel syndrome (SBS) market, segmented by distribution channel, includes hospital pharmacies and online & retail pharmacies. Hospital pharmacies play a pivotal role in providing specialized treatments for SBS patients, particularly for those requiring complex therapies like parenteral nutrition (PN), intravenous medications, and growth factors such as teduglutide. Hospital pharmacies are equipped to handle the unique needs of SBS patients, ensuring that they receive the correct dosage and therapy under medical supervision. These pharmacies also offer personalized care and consultations for patients, providing a higher level of service in a clinical setting.
Online and retail pharmacies have seen an increase in demand for SBS-related treatments due to the growing trend of home-based care. Online pharmacies offer the convenience of ordering medications, nutritional supplies, and accessories necessary for managing SBS from the comfort of home, which is especially important for patients who require long-term management and prefer not to visit hospitals or clinics frequently. Retail pharmacies, on the other hand, are critical in providing easily accessible medications for SBS management, including oral medications to control symptoms like diarrhea or pain. These pharmacies provide quick access to treatments and allow for a wider distribution of SBS-related medications, improving patient convenience and adherence to treatment regimens.
Geographically, hospital pharmacies are more prominent in developed regions such as North America and Europe, where patients often require inpatient care and intensive monitoring, particularly for severe cases of SBS. In contrast, online and retail pharmacies are growing rapidly in regions like Asia-Pacific and Latin America, where patients benefit from the convenience of accessing medications and home-based treatment options. The increasing reliance on online platforms for medical supplies, especially for chronic conditions like SBS, is expected to fuel the demand for these distribution channels in the coming years, making treatment more accessible and affordable for a broader patient base.
Global Short Bowel Syndrome Market, Segmentation by Geography
In this report, the Global Short Bowel Syndrome Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Short Bowel Syndrome Market Share (%), by Geographical Region, 2024
Geographically, the global short bowel syndrome market is divided into key regions, including North America, Europe, Asia Pacific, the Middle East and Africa, and Latin America. North America and Europe are anticipated to dominate the market shares due to their well-established healthcare infrastructures, high prevalence rates of gastrointestinal disorders, and favorable regulatory environments for drug approval. These regions also benefit from substantial investments in research and development activities, fostering innovation in therapeutic options for short bowel syndrome. Additionally, the presence of key market players and advanced healthcare systems further contribute to market growth in North America and Europe.
On the other hand, the Asia Pacific region is poised to witness significant growth during the forecast period, driven by factors such as rising healthcare expenditure, expanding patient populations, and improving access to medical services. As healthcare infrastructure continues to develop and awareness about short bowel syndrome increases among healthcare providers and patients, emerging markets in Latin America and the Middle East and Africa are also expected to contribute to market expansion. Overall, the global short bowel syndrome market is projected to experience substantial growth, propelled by expanding therapeutic options and increasing demand across diverse geographic regions.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Short Bowel Syndrome Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers
- Advancements in Therapeutic Options
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Increasing Prevalence of Gastrointestinal Disorders:The rising prevalence of gastrointestinal disorders, such as Crohn's disease and intestinal resections, contributes to the growing patient population with short bowel syndrome. As the incidence of these underlying conditions increases globally, so does the demand for effective treatments for short bowel syndrome, driving market growth.
Ongoing research and development efforts have led to advancements in therapeutic options for short bowel syndrome, including novel drugs and treatment approaches. These advancements offer improved efficacy and tolerability, providing patients with more effective management of their condition and better quality of life.
Restraints
- Limited Awareness and Diagnosis:
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High Treatment Costs:The cost of treatment for short bowel syndrome, including medications, nutritional support, and surgical interventions, can be significant. High treatment costs may pose a barrier to access for some patients, particularly in regions with limited healthcare resources or inadequate insurance coverage, restraining market growth.
Short bowel syndrome is a complex and often underdiagnosed condition, leading to limited awareness among healthcare providers and patients. This lack of awareness may result in delays in diagnosis and treatment initiation, hindering market growth and impacting patient outcomes.
Opportunities
- Emerging Markets
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Technological Innovations:Technological advancements in drug delivery systems and medical devices offer opportunities for innovation in short bowel syndrome treatment. Novel delivery methods and devices may improve treatment efficacy, patient adherence, and convenience, enhancing the overall patient experience and driving market growth.
Emerging markets in regions such as Asia Pacific, Latin America, and the Middle East and Africa present significant growth opportunities for the short bowel syndrome market. As healthcare infrastructure improves and awareness about the condition increases in these regions, there is a growing demand for effective treatments, driving market expansion.
Competitive Landscape Analysis
Key players in Global Short Bowel Syndrome Market includ:
- Shire plc (Takeda Pharmaceutical Company Limited)
- Zealand Pharma A/S
- Sancilio & Company, Inc.
- OxThera
- Nutrinia Ltd
- Ardelyx, Inc.
- Emmaus Life Sciences, Inc.
- GLyPharma Therapeutic, Inc. (Pfizer Inc.)
- Merck KGaA
- Naia Pharmaceuticals
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Drug Class
- Market Snapshot, By Region
- Global Short Bowel Syndrome Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- High cost of parenteral nutrition increases demand for SBS drugs
- Favorable reimbursement scenario
- Restraints
- Side effects associated with SBS drugs
- Non-availability of approved drugs globally
- Opportunities
- Demand for SBS drugs
- Reimbursement scenario
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Short Bowel Syndrome Market, By Drug Class, 2021 - 2031 (USD Million)
- Glucagon-like Peptide-2 (GLP-2)
- Growth Hormone
- Glutamine
- Others
- Global Short Bowel Syndrome Market, By Distribution Channel, 2021 - 2031 (USD Million)
- Hospital Pharmacies
- Online & Retail Pharmacies
- Global Short Bowel Syndrome Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Short Bowel Syndrome Market, By Drug Class, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Shire plc (Takeda Pharmaceutical Company Limited)
- Zealand Pharma A/S
- Sancilio & Company, Inc.
- OxThera
- Nutrinia Ltd
- Ardelyx, Inc.
- Emmaus Life Sciences, Inc.
- GLyPharma Therapeutic, Inc. (Pfizer Inc.)
- Merck KGaA
- Naia Pharmaceuticals, Inc.
- Company Profiles
- Analyst Views
- Future Outlook of the Market