Global Apheresis Market Growth, Share, Size, Trends and Forecast (2024 - 2030)
By Product;
Centrifugation and Membrane Filtering.By Procedure;
Donor and Therapeutic.By Application;
Plasmapheresis and Plateletpheresis.By End-User;
Hospital and Blood Collection Center.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa, and Latin America - Report Timeline (2020 - 2030).Introduction
Global Apheresis Market (USD Million), 2020 - 2030
In the year 2023, the Global Apheresis Market was valued at USD xx.x million. The size of this market is expected to increase to USD xx.x million by the year 2030, while growing at a Compounded Annual Growth Rate (CAGR) of x.x%.
The Apheresis market has witnessed significant growth and transformative shifts, driven by factors such as technological advancements, and increasing demand for blood components. The pandemic underscored the critical role of apheresis in treating patients, particularly through plasma therapy, leading to a surge in market demand. While the initial impact of the pandemic disrupted supply chains and reduced blood donations, the widespread adoption of apheresis units for plasma extraction bolstered market growth. Despite a slight slowdown post-pandemic, the market is expected to maintain stable growth fueled by ongoing technological innovations and increasing applications in disease management. Propelling the growth of the apheresis market are factors such as the rising burden of diseases and the growing demand for safe blood components. Technological advancements have led to the development of new apheresis techniques, enhancing the efficiency and efficacy of treatments. Favorable reimbursement policies and funding initiatives, exemplified by NHS England's adoption of automated red blood cell exchange treatment for sickle cell disease, further drive market expansion. Apheresis procedures are increasingly utilized as primary or adjunctive therapies for various diseases, including thrombotic thrombocytopenic purpura, autoimmune diseases, and hemolytic uremic syndrome, highlighting the versatility and importance of this medical intervention. Product innovations and approvals play a pivotal role in driving market growth. Companies like Terumo Blood and Cell Technologies are expanding the functionality of apheresis systems, enabling physicians to perform advanced procedures at the patient's bedside. Challenges such as the lack of skilled professionals, blood contamination, and cost concerns pose constraints to market growth. With continuous advancements and expanding applications, the apheresis market is poised for healthy growth in the coming years.
Global Apheresis Market Recent Developments
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In July 2022, Terumo Blood and Cell Technologies entered into a collaboration with Eliaz Therapeutics to develop and commercialize an innovative therapeutic apheresis treatment for acute kidney injury (AKI).
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In June 2022, Terumo Blood and Cell Technologies announced that the UK's NHS England had chosen the automated red blood cell exchange (RBCX) procedure, conducted using the Spectra Optia Apheresis System, under the NHS MedTech Funding Mandate (MTFM) to address sickle cell disease. This decision is set to facilitate broader implementation of the Spectra Optia system in hospitals throughout England, thereby improving access to this transformative treatment for patients with sickle cell disease.
Segment Analysis
The Global Apheresis Market has been segmented into several key categories, including Product, Procedure, Application, and End-User, each addressing unique aspects of apheresis technology and its uses in healthcare. By Product, the market is divided into Centrifugation and Membrane Filtering. Centrifugation is the most commonly used method, separating blood components based on their density by spinning the blood at high speeds. This technique is efficient for separating plasma, platelets, and red blood cells, making it widely used in both donor and therapeutic apheresis. On the other hand, Membrane Filtering utilizes selective filtration through a membrane to separate desired components, offering advantages in precision and minimizing blood cell loss. While both methods serve important roles, centrifugation is more widely used, particularly for large-scale blood component collection, while membrane filtration is preferred in more targeted or specialized applications.
The market is also segmented by Procedure into Donor and Therapeutic. Donor apheresis procedures are primarily used in blood donation centers to collect specific blood components, such as plasma and platelets, from healthy individuals. This segment is critical for ensuring an adequate supply of blood products for transfusions, particularly for patients with blood disorders or those requiring surgery. In contrast, Therapeutic apheresis is used to treat medical conditions by removing harmful substances like antibodies, abnormal cells, or toxins from the patient’s blood. Therapeutic apheresis is increasingly utilized to manage autoimmune diseases, kidney disorders, and certain cancers. Both donor and therapeutic procedures are essential, but the therapeutic segment is expanding as more diseases are being treated with apheresis technology.
By Application, the market is divided into Plasmapheresis and Plateletpheresis. Plasmapheresis is widely used in therapeutic apheresis to treat conditions such as autoimmune diseases, neurological disorders, and kidney diseases by removing harmful plasma components and replacing them with healthy plasma or other fluids. Plateletpheresis, on the other hand, focuses on the collection of platelets, which are crucial for patients with blood disorders like thrombocytopenia or those undergoing chemotherapy. As the demand for both plasma and platelets grows, the need for efficient apheresis techniques is expanding. The End-User segment includes Hospitals and Blood Collection Centers. Hospitals are key users of therapeutic apheresis, treating patients with severe medical conditions, while Blood Collection Centers are critical for the collection of blood components for transfusions. Both sectors are vital for the proper functioning of the apheresis market, supporting both the clinical treatment of patients and the supply of blood components to meet global healthcare demands.
Global Apheresis Segment Analysis
In this report, the Global Apheresis Market has been segmented by Product, Procedure, Application, End User, and Geography.
Global Apheresis Market, Segmentation by Product
The Global Apheresis Market has been segmented by Product into Centrifugation and Membrane Filtering.
Centrifugation involves the use of centrifugal force to separate blood components based on their density. This method is widely employed in apheresis systems, facilitating efficient separation of components such as red blood cells, plasma, and platelets. Centrifugation-based apheresis systems offer precise control over component separation, making them suitable for various therapeutic and donor apheresis procedures. They play a crucial role in treating a wide range of medical conditions, including autoimmune diseases, hematological disorders, and neurological disorders.
Membrane filtering techniques utilize specialized membranes to selectively remove specific blood components based on size or affinity. This method allows for precise separation of components such as immunoglobulins, plasma, and white blood cells. Membrane filtering-based apheresis systems offer targeted treatment options for conditions requiring the removal of specific substances from the blood. They are particularly useful in therapeutic apheresis procedures aimed at managing autoimmune diseases and neurological disorders by eliminating disease-causing elements from the bloodstream. Both centrifugation and membrane filtering technologies contribute significantly to the advancement of the apheresis market, providing healthcare professionals with versatile tools for treating a wide range of medical conditions.
Global Apheresis Market, Segmentation by Procedure
The Global Apheresis Market has been segmented by Procedure into Donor and Therapeutic.
The Global Apheresis Market has been segmented by Procedure into two key categories: Donor and Therapeutic. The Donor procedure segment primarily involves apheresis techniques used in blood donation centers, where blood components such as plasma, platelets, or red blood cells are collected from healthy individuals for transfusion purposes. This type of apheresis is essential in maintaining blood banks and providing critical blood components for patients in need, especially in emergency situations or for those with chronic conditions that require regular transfusions. Donor apheresis is typically conducted on individuals who are in good health, and it helps in ensuring the continuous availability of vital blood products.
On the other hand, the Therapeutic procedure segment refers to apheresis techniques used in medical treatment, where blood components are removed, replaced, or modified to treat certain diseases. Therapeutic apheresis is employed to treat a variety of conditions, including autoimmune diseases, kidney disorders, and certain types of cancer. The process may involve removing harmful substances such as antibodies, toxins, or abnormal cells from the blood. This procedure is typically performed on patients with specific medical conditions where traditional treatments have proven ineffective, offering a targeted approach to manage or alleviate symptoms.
Both Donor and Therapeutic apheresis procedures are vital components of the apheresis market, but they serve distinct purposes. The Donor segment is largely driven by the need for blood components in medical settings, while the Therapeutic segment is increasingly important as more chronic and complex diseases are being managed through apheresis techniques. Advances in technology have made therapeutic apheresis more efficient, expanding its use in treating a wider range of conditions. As the demand for both donor blood and innovative treatments grows, the apheresis market continues to evolve, offering critical solutions for both preventive and therapeutic healthcare needs.
Global Apheresis Market, Segmentation by Application
The Global Apheresis Market has been segmented by Application into Plasmapheresis and Plateletpheresis.
The Global Apheresis Market has been segmented by Application into Plasmapheresis and Plateletpheresis, each addressing distinct therapeutic and medical needs. Plasmapheresis is a procedure in which plasma is separated from the other blood components and removed from the body. This application is primarily used for therapeutic purposes, such as in the treatment of autoimmune diseases, neurological disorders, and certain kidney conditions. Plasmapheresis is also used in plasma exchange therapies to remove harmful antibodies, toxins, or abnormal proteins from the blood, offering significant relief for patients suffering from conditions like Guillain-Barré syndrome, myasthenia gravis, and lupus. The growing demand for plasmapheresis is driven by the increasing prevalence of autoimmune disorders and the expanding indications for this treatment.
Plateletpheresis, on the other hand, is the process of selectively separating and collecting platelets from the blood while returning the rest of the blood components to the donor or patient. This application is mainly utilized in blood donation centers and hospitals for the collection of platelets, which are essential for treating patients with blood disorders, such as thrombocytopenia, leukemia, or other conditions that affect platelet counts. Plateletpheresis has a significant role in maintaining a steady supply of platelets for transfusions, especially in oncology and hematology departments, where platelet transfusions are crucial for cancer patients undergoing chemotherapy. The increased need for platelet supplies, especially in regions with higher cancer rates, is a key driver of the plateletpheresis segment.
Both Plasmapheresis and Plateletpheresis are integral applications within the apheresis market, but they cater to different aspects of healthcare needs. While plasmapheresis is primarily focused on the treatment of specific medical conditions by removing harmful substances from the blood, plateletpheresis plays a vital role in the collection of platelets for transfusion, benefiting patients with blood-related disorders. The growing awareness of the therapeutic benefits of these procedures, along with advancements in apheresis technologies, is expected to drive the market for both applications. As medical research continues to identify new therapeutic uses for apheresis, these applications will likely see continued growth, benefiting a broader patient population.
Global Apheresis Market, Segmentation by End User
The Global Apheresis Market has been segmented by End User into Hospital and Blood Collection Center.
The Global Apheresis Market has been segmented by End User into Hospitals and Blood Collection Centers, each playing a crucial role in the utilization and application of apheresis procedures. Hospitals are one of the primary end users of apheresis technologies, particularly for therapeutic apheresis. Hospitals often perform apheresis on patients to treat a range of medical conditions, including autoimmune diseases, kidney disorders, and certain types of cancer. The therapeutic use of apheresis, such as plasmapheresis or plateletpheresis, is typically conducted in hospital settings where patients are closely monitored, and medical teams are available to manage any complications or adverse reactions. The growing prevalence of chronic diseases and the need for specialized treatments in hospitals continue to drive the demand for apheresis services in these settings.
Blood Collection Centers are another key segment in the apheresis market, focusing primarily on the collection of blood components such as plasma, platelets, and red blood cells. Apheresis in blood collection centers is typically used for donor purposes, where healthy individuals undergo procedures to donate specific blood components for use in transfusions. These centers play a vital role in ensuring an adequate supply of blood products, particularly platelets and plasma, which are essential for patients with blood disorders, those undergoing surgery, or cancer patients in need of transfusions. The increasing demand for blood products, especially for patients with thrombocytopenia and other blood-related conditions, has contributed to the growth of apheresis procedures in blood collection centers.
Both hospitals and blood collection centers are essential in the overall apheresis ecosystem, with hospitals focusing on the therapeutic aspects of apheresis and blood collection centers dedicated to the collection and distribution of blood components. The demand in hospitals is driven by the need for advanced treatments for a wide range of medical conditions, while blood collection centers continue to see growth as the need for blood donations rises globally. As healthcare needs evolve, both end users will likely see continued growth in their utilization of apheresis technologies, with hospitals expanding therapeutic apheresis treatments and blood collection centers increasing their role in providing critical blood products.
Global Apheresis Market, Segmentation by Geography
In this report, the Global Apheresis Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Apheresis Market Share (%), by Geographical Region, 2023
North America is poised for growth in the apheresis market, driven by the increasing burden of various blood-related ailments such as kidney diseases, metabolic diseases, cancer, and neurological disorders. With a well-established healthcare infrastructure and high levels of patient awareness, the region is witnessing a surge in demand for apheresis procedures. Notably, organizations like the Leukemia & Lymphoma Society have highlighted the alarming frequency of blood cancer diagnoses in the United States, further emphasizing the need for advanced treatment options like apheresis. The prevalence of these target diseases acts as a significant driver for market expansion in the region.
The increasing availability of reimbursement policies for apheresis procedures and devices is fueling market growth. Policies issued by entities like the United Healthcare Group provide coverage for apheresis procedures across various indications, except for stem cell collection for transplantation purposes. This expanded coverage enhances accessibility to apheresis treatments among the target population, thereby driving market demand. Initiatives such as Apheresis Awareness Day, declared by the American Society for Apheresis, aim to raise awareness about the importance of apheresis medicine and recognize the contributions of donors, patients, and healthcare professionals. These factors collectively contribute to the significant growth expected in the North American apheresis market in the coming years.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Apheresis Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunities Analysis
Drivers:
- Growing Incidence of Chronic Diseases
- Technological Developments in Therapeutic Apheresis Methods
- Increasing Utilization in Oncology and Hematology
- Growing Need for Therapeutic Plasma Exchange (TPE)
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Growing Geriatric Population: As demographics shift, with a significant proportion of the global population aging, the prevalence of age-related diseases and conditions is on the rise. Geriatric individuals are more susceptible to various ailments that require therapeutic interventions, including autoimmune disorders, hematological disorders, and neurological conditions.The demand for apheresis procedures among the elderly population is increasing steadily. Apheresis therapies play a crucial role in managing these conditions by removing harmful substances or excess components from the blood, thereby alleviating symptoms and improving quality of life for elderly patients.
As the geriatric population continues to expand, there is a growing need for personalized and specialized healthcare solutions tailored to their unique medical needs. Apheresis procedures offer a targeted approach to treatment, allowing for the selective removal of specific blood components or toxins associated with age-related conditions. This personalized approach enhances treatment efficacy while minimizing the risk of adverse effects, making apheresis an attractive therapeutic option for elderly patients. Additionally, advancements in apheresis technology have led to the development of safer and more efficient procedures, further contributing to the growing acceptance of apheresis among geriatric populations.
The aging population presents both challenges and opportunities for the apheresis market. While the increasing prevalence of age-related diseases drives demand for apheresis procedures, it also places strain on healthcare systems and resources. Healthcare providers must adapt to the unique needs of elderly patients, including specialized training for apheresis technicians and the development of age-friendly healthcare facilities. Initiatives aimed at promoting healthy aging and preventative healthcare measures can help mitigate the burden of age-related illnesses, potentially reducing the demand for apheresis treatments in the long term.
Restraints:
- Expensive Techniques and Equipment
- Difficulties with Reimbursement
- Complexity and Training Requirements
- Low Awareness and Access
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Safety Issues and Adverse Events: Safety issues and adverse events are critical considerations in the domain of the global apheresis market, as they directly impact patient outcomes and treatment efficacy. Despite its therapeutic benefits, apheresis procedures carry inherent risks that must be carefully managed to ensure patient safety. One of the primary safety concerns associated with apheresis is the potential for adverse reactions to anticoagulants used during the procedure. Anticoagulants are necessary to prevent blood clotting within the apheresis system, but they can sometimes lead to allergic reactions or other adverse effects in patients. Healthcare providers must closely monitor patients for signs of adverse reactions and take appropriate measures to mitigate them during the procedure.
Complications related to vascular access represent another safety issue in apheresis procedures. Establishing and maintaining vascular access is essential for successful apheresis treatment, but it can sometimes pose challenges such as hematoma formation, infection, or thrombosis. Healthcare professionals must have the necessary skills and expertise to ensure proper vascular access and minimize the risk of complications. Regular monitoring of vascular access sites and prompt intervention in case of any abnormalities are crucial for preventing adverse events and ensuring patient safety throughout the procedure.
Adverse events associated with transfusions represent a significant safety concern in the apheresis market. While apheresis treatments involving blood component transfusions can be life-saving for patients, they also carry the risk of transfusion-related adverse reactions. These reactions may include febrile non-hemolytic reactions, allergic reactions, or even transfusion-transmitted infections in rare cases. Healthcare providers must adhere to strict protocols for blood component transfusions, including thorough screening of donors and compatibility testing, to minimize the risk of adverse events. Vigilant monitoring of patients during and after transfusions is essential for early detection and management of any adverse reactions, thereby ensuring the safety and well-being of patients undergoing apheresis treatments.
Opportunities:
- Rising Demand for Blood Components
- Expansion of Healthcare Infrastructure
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Focus on Personalized Medicine: There is a growing emphasis on personalized medicine, which tailors treatment approaches to individual patients based on their unique characteristics, including genetic makeup, lifestyle factors, and disease profiles. Personalized medicine represents a paradigm shift from the traditional one-size-fits-all approach to healthcare, offering more precise and targeted interventions. Apheresis, as a therapeutic modality, aligns with the principles of personalized medicine by providing customizable treatment options that can be tailored to meet the specific needs of each patient.
Aspect of personalized medicine in apheresis involves optimizing treatment protocols based on individual patient responses and disease progression. By monitoring patient outcomes and adjusting treatment parameters accordingly, healthcare providers can optimize the efficacy of apheresis therapies while minimizing adverse effects. In patients undergoing therapeutic apheresis for autoimmune diseases, treatment regimens can be customized based on factors such as disease severity, response to previous therapies, and comorbidities, ensuring a personalized approach to care.
Advances in technology and biomarker research are facilitating the development of novel personalized apheresis strategies. Biomarkers, which are measurable indicators of biological processes or disease states, play a crucial role in guiding treatment decisions and predicting patient responses to therapy. By leveraging biomarker data, healthcare providers can identify optimal candidates for apheresis treatments, tailor treatment protocols to individual patient profiles, and monitor treatment response over time. This personalized approach not only enhances treatment outcomes but also reduces the likelihood of unnecessary interventions and adverse events, thereby improving patient care in the global apheresis market.
Competitive Landscape Analysis
Key players in Global Apheresis Market include:
- Fresenius SE & Co. KGaA
- Haemonetics Corporation
- Terumo Corporation
- B. Braun Melsungen AG
- Asahi Kasei Corporation
- Cerus Corporation
- Kawasumi Laboratories, Inc
- HemaCare Corporation
- Kaneka Corporation
- Grifols, S.A
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product
- Market Snapshot, By Procedure
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Market Snapshot, By Application
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Market Snapshot, By End User
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Market Snapshot, By Region
- Global Apheresis Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Growing Incidence of Chronic Diseases
- Technological Developments in Therapeutic Apheresis Methods
- Increasing Utilization in Oncology and Hematology
- Growing Need for Therapeutic Plasma Exchange (TPE)
- Growing Geriatric Population
- Restraints
- Expensive Techniques and Equipment
- Difficulties with Reimbursement
- Complexity and Training Requirements
- Low Awareness and Access
- Safety Issues and Adverse Events
- Opportunities
- Rising Demand for Blood Components
- Expansion of Healthcare Infrastructure
- Focus on Personalized Medicine
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Apheresis Market, By Product, 2020 - 2030 (USD Million)
- Centrifugation
- Membrane Filtering
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Global Apheresis Market, By Procedure, 2020 - 2030 (USD Million)
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Donor
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Therapeutic
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Global Apheresis Market, By Application, 2020 - 2030 (USD Million)
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Plasmapheresis
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Plateletpheresis
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- Global Apheresis Market, By End User, 2020 - 2030 (USD Million)
- Hospital
- Blood Collection Center
- Global Apheresis Market, By Geography, 2020 - 2030 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Apheresis Market, By Product, 2020 - 2030 (USD Million)
- Competitive Landscape
- Company Profiles
- Fresenius SE & Co. KGaA
- Haemonetics Corporation
- Terumo Corporation
- B. Braun Melsungen AG
- Asahi Kasei Corporation
- Cerus Corporation
- Kawasumi Laboratories, Inc
- HemaCare Corporation
- Kaneka Corporation
- Grifols, S.A
- Company Profiles
- Analyst Views
- Future Outlook of the Market