Global Organ Preservation Market Growth, Share, Size, Trends and Forecast (2024 - 2030)

Recent Developments:

• January 2023: Transplant surgeons at MedStar Georgetown University Hospital in the Washington Metropolitan area of the United States successfully utilized a new FDA-approved technology, the OrganOx metra, which simulates connecting a liver to its recipient, allowing the donated liver to be preserved for up to 12 hours before being transplanted into the recipient

• August 2022: Paragonix Technologies, Inc. announced a significant milestone of preserving over 2,000 donor organs while providing transplant hospitals with Advanced Organ Preservation (AOPT) technology and a statewide clinical support network. Each of these technologies employs first-of-their-kind preservation methods and has significantly improved conventional ice and cooler practices.

• January 2022: A university spinoff, OrganOx, a global pioneer in normothermic machine perfusion (NMP), announced that the Food and Drug Administration has awarded premarket clearance (PMA) for their metra system. OrganOx metra is a revolutionary organ preservation device created by researchers in Biomedical Engineering and Surgery.

The Global Organ Preservation Market is segmented by preservation solution, technique, organ, and end-user, each playing a critical role in advancing organ preservation technologies for transplant purposes.

By preservation solution, the market is divided into static cold storage solutions, machine perfusion solutions, and others. Static cold storage solutions are the most commonly used preservation method, where organs are stored in a cold environment to slow metabolic activity and prevent damage. These solutions typically contain a combination of electrolytes, nutrients, and protective agents to preserve organ integrity. Machine perfusion solutions, on the other hand, involve continuous circulation of a preservation solution through the organ, maintaining its viability for a longer duration. This method is gaining popularity, particularly for organs like kidneys and livers, as it can improve graft function and reduce the risk of organ rejection post-transplantation.

By technique, the market is segmented into static cold storage, machine perfusion, and others. Static cold storage, as mentioned, is the traditional and widely used method, where organs are cooled and stored in an iced solution. Machine perfusion, as an advanced preservation technique, is further divided into hypothermic perfusion, normothermic perfusion, and hyperthermic perfusion. These techniques involve the perfusion of organs at specific temperatures and with specialized solutions to maintain organ function, particularly during transportation between donor and recipient. Hypothermic perfusion is the most common, involving cold solutions to minimize metabolic activity, while normothermic and hyperthermic perfusion techniques are newer, with the potential to better simulate the physiological environment of the organ and enhance recovery post-transplant.

By organ, the market is divided into heart, liver, kidney, lung, pancreas, and others. The liver and kidneys are the most commonly transplanted organs, driving the demand for advanced preservation techniques. Lungs and hearts are more sensitive and require advanced preservation methods like machine perfusion to improve viability and reduce ischemia. The pancreas is often preserved through static cold storage, while newer techniques, such as machine perfusion, are increasingly being tested to improve outcomes.

By end-user, the market includes hospitals, transplant centers, organ procurement organizations, and research institutions. Hospitals and transplant centers are the largest end-users, responsible for conducting transplants and utilizing organ preservation methods for optimal patient outcomes. Organ procurement organizations and research institutions play a significant role in the development and advancement of preservation technologies and techniques. The increasing adoption of organ preservation solutions by these end-users is expected to propel the growth of the market.

Overall, the organ preservation market is driven by the demand for improved preservation techniques that enhance organ viability, reduce organ rejection, and improve patient outcomes in organ transplantation.

Global Organ Preservation Market Analysis

In this report, the Global Organ Preservation Market has been segmented by Preservation Soultion, Technique, Organ, End-User and Geography.

Global Organ Preservation Market, Segmentation by Preservation Soultion

The Global Organ Preservation Market has been segmented by Preservation Soultion into University of Wisconsin Solution (UW Solution) , Custodiol HTK , Perfadex and Others.

One of the key segmentation factors shaping this market is the type of preservation solution used. Among these solutions, the University of Wisconsin Solution (UW Solution) holds a prominent position. UW Solution is widely used for preserving various organs such as the liver, kidney, and pancreas during transplantation surgeries. Its ability to maintain cellular integrity and viability of organs over an extended period has made it a preferred choice among transplant surgeons.

Another noteworthy preservation solution in the market is Custodiol HTK (histidine-tryptophan-ketoglutarate). This solution is primarily used for heart and liver preservation and has gained popularity due to its effectiveness in preventing cellular damage during the transplantation process. Additionally, Custodiol HTK's ability to minimize ischemic injury has contributed to its adoption in organ preservation procedures worldwide.

Perfadex is another significant preservation solution utilized in lung transplantation. It is specially formulated to maintain the functionality and integrity of lungs during storage and transportation before transplantation. Perfadex has shown promising results in preserving lung function and reducing the risk of complications post-transplantation.

Apart from these prominent solutions, the market also includes other preservation solutions catering to specific organ preservation needs. These solutions may vary in composition and application but aim to achieve the common goal of preserving organ viability and function until transplantation. With ongoing research and development activities, the market is expected to witness further advancements in organ preservation solutions, catering to the evolving needs of transplant surgery and improving patient outcomes.

Global Organ Preservation Market, Segmentation by Technique

The Global Organ Preservation Market has been segmented by Technique into Static Cold Storage (SCS) Technique , Hypothermic Machine Perfusion and Normothermic Machine Perfusion.

One of the primary methods utilized is the Static Cold Storage (SCS) Technique. This traditional method involves immersing the organ in a cold preservation solution to slow metabolic processes and reduce cellular damage. SCS has been the standard technique for decades due to its simplicity and cost-effectiveness, making it widely accessible across various healthcare settings, especially in resource-limited regions. However, it does have limitations, such as limited preservation time and potential damage to the organ during rewarming.

In recent years, Hypothermic Machine Perfusion (HMP) has emerged as a promising alternative to SCS. HMP involves continuously perfusing the organ with a cold preservation solution while maintaining a controlled temperature and pressure. This technique offers several advantages over SCS, including better preservation of organ function and viability, extended preservation times, and the ability to assess organ quality before transplantation. HMP is particularly beneficial for marginal organs or those from extended criteria donors, improving transplant outcomes and reducing the risk of organ rejection.

Normothermic Machine Perfusion (NMP) represents the latest advancement in organ preservation technology. Unlike SCS and HMP, which rely on cold temperatures to slow metabolism, NMP maintains organs at near-physiological conditions, including normal body temperature. By perfusing the organ with oxygenated blood or a specialized preservation solution, NMP mimics the natural physiological environment, allowing for metabolic activity and cellular repair to occur. This technique holds great promise for improving organ quality and expanding the donor pool by rejuvenating marginal organs that would otherwise be discarded. Additionally, NMP enables ex vivo assessment and optimization of organ function, further enhancing transplant outcomes and reducing the incidence of organ rejection. As research and development in organ preservation continue to advance, these innovative techniques are expected to play a crucial role in addressing the growing demand for transplantable organs worldwide.

Global Organ Preservation Market, Segmentation by Organ

The Global Organ Preservation Market has been segmented by Organ into Kidney , Liver , Lung , Heart and Others.

The Kidney segment holds a substantial share in the market due to the growing prevalence of end-stage renal diseases and the rising number of kidney transplants worldwide. Organ preservation solutions designed specifically for kidneys have improved transplant outcomes and expanded the pool of available organs for transplantation, thereby driving market growth.

The Liver segment is also experiencing robust growth owing to the high demand for liver transplants resulting from liver diseases such as cirrhosis, hepatitis, and liver cancer. Organ preservation techniques have played a crucial role in extending the viability of donor livers and improving transplant success rates, fueling the demand for liver preservation solutions globally.

In addition to kidneys and livers, the Lung, and Heart segments are witnessing significant traction in the organ preservation market. The increasing prevalence of respiratory and cardiovascular diseases has led to a rise in lung and heart transplant procedures, driving the demand for advanced organ preservation solutions tailored to these organs. Moreover, ongoing research and development efforts aimed at enhancing organ preservation techniques are expected to further propel market growth across all segments in the foreseeable future.

Global Organ Preservation Market, Segmentation by End-User

The Global Organ Preservation Market has been segmented by End-User Soultion into Hospitals and Clinics, Organ Banks, and Others.

Hospitals and clinics are the primary end-users of organ preservation solutions. These healthcare facilities are responsible for performing organ transplantations, making them essential in utilizing preservation technologies to ensure that organs remain viable for transplantation. Hospitals use various preservation methods, including static cold storage and machine perfusion, to maintain organ quality during transportation from the donor to the recipient. As transplant surgery is a highly time-sensitive procedure, the need for effective organ preservation is critical to achieving successful outcomes. Hospitals and clinics are also involved in research and development to improve preservation techniques and extend the viability of organs.

Organ banks are specialized facilities that store and manage organs for transplantation purposes. These organizations play a vital role in the organ preservation process by maintaining the quality and viability of organs until they are ready for transplantation. Organ banks utilize advanced preservation solutions and techniques, including machine perfusion and static cold storage, to ensure that donated organs are preserved optimally until they are matched with a recipient. Organ banks also play an essential role in the logistics of organ distribution, working closely with hospitals, transplant centers, and procurement organizations to facilitate timely and safe organ transplantation.

Other end-users in the organ preservation market include organ procurement organizations (OPOs), research institutions, and biotechnology companies. OPOs are responsible for the recovery and transportation of organs from donors, while research institutions and biotechnology companies focus on advancing preservation technologies and conducting clinical trials. These organizations contribute to the development of innovative solutions that improve organ preservation techniques and expand the availability of transplantable organs.

Overall, the increasing adoption of advanced organ preservation methods by hospitals, organ banks, and other end-users is driving the growth of the organ preservation market.

Global Organ Preservation Market, Segmentation by Geography

In this report, the Global Organ Preservation Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.

Global Organ Preservation Market Share (%), by Geographical Region, 2023

North America holds a prominent share in the global organ preservation market, primarily due to the presence of well-established healthcare infrastructure, high adoption of advanced medical technologies, and increasing organ transplantation procedures in countries like the United States and Canada. Additionally, favorable government initiatives and reimbursement policies further contribute to the growth of the market in this region.

Europe is another significant market for organ preservation, characterized by a growing geriatric population and rising incidences of chronic diseases leading to organ failure. Countries like Germany, the UK, and France are at the forefront of organ preservation research and development, driving market growth through investments in innovative technologies and supportive regulatory frameworks.

The Asia Pacific region is poised to witness rapid growth in the organ preservation market, fueled by improving healthcare infrastructure, rising disposable incomes, and increasing awareness about organ donation and transplantation. Countries like China, Japan, and India are investing in expanding their organ preservation capabilities to meet the growing demand for transplant procedures.

In the Middle East and Africa, the organ preservation market is growing steadily, supported by government initiatives to improve healthcare infrastructure and increase access to transplantation services. However, challenges such as limited awareness about organ donation and transplantation and infrastructure constraints hinder market growth to some extent.

Latin America represents a growing market for organ preservation, driven by increasing investments in healthcare infrastructure and rising prevalence of chronic diseases requiring organ transplantation. Countries like Brazil and Mexico are witnessing a surge in organ transplantation procedures, creating opportunities for market players to expand their presence in the region.

This report provides an in depth analysis of various factors that impact the dynamics of Global Organ Preservation Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.

Drivers:

• Aging population
• Organ shortage
• Technological advancements
• Increased transplant surgeries

• Rising prevalence of chronic diseases: The global organ preservation market is experiencing a significant surge, primarily attributed to the rising prevalence of chronic diseases worldwide. Chronic diseases such as cardiovascular diseases, diabetes, kidney diseases, and liver diseases are on the rise due to factors like sedentary lifestyles, unhealthy dietary habits, and aging populations. These conditions often lead to organ failure, necessitating organ transplantation as a life-saving treatment option. As the demand for organs continues to surpass the availability of suitable donors, organ preservation technologies play a crucial role in extending the viability of organs during transportation and storage, thereby increasing the chances of successful transplantation. This growing demand for organ preservation solutions is driving innovation and investment in the field, leading to the development of advanced preservation techniques and devices that enhance organ quality and transplant outcomes.

  Advancements in medical technology and research have facilitated the development of novel organ preservation techniques that enable prolonged preservation times and improve the viability of organs. For instance, machine perfusion technologies, such as hypothermic and normothermic perfusion systems, allow for better organ preservation by maintaining optimal conditions for organ function outside the body. These systems not only help in preserving organs for longer durations but also enable the assessment of organ viability before transplantation, reducing the risk of graft failure and rejection. Additionally, the adoption of organ preservation solutions is further bolstered by the increasing emphasis on expanding organ procurement and transplantation programs globally, coupled with supportive government initiatives and collaborations among healthcare organizations and research institutions to address the growing demand for organs. As a result, the organ preservation market is poised for significant growth in the coming years, driven by the increasing need for effective organ preservation solutions to meet the rising demand for organ transplantation and improve patient outcomes.

Restraints:

• Limited organ preservation methods
• Regulatory challenges
• High cost of organ preservation
• Lack of awareness

• Ethical concerns: The advancement of organ preservation technologies has opened new frontiers in the field of transplantation, offering hope to millions of patients awaiting life-saving organ transplants. However, alongside the remarkable progress, ethical concerns loom large. One major ethical dilemma revolves around the allocation of preserved organs. With demand far exceeding supply, questions arise regarding the fairness and equity of distribution. Should organs be allocated based on medical urgency, recipient's socioeconomic status, or other criteria? Balancing the principles of justice, beneficence, and autonomy becomes increasingly complex when determining who receives access to these limited resources.

  The ethical considerations extend beyond allocation to the very process of organ preservation itself. As technologies evolve to extend the viability of organs ex vivo, concerns emerge regarding the boundary between life and death. Prolonging the preservation of organs raises questions about the definition of death and the ethical implications of intervening in the natural dying process. Additionally, ensuring the informed consent of donors and respecting their autonomy becomes paramount, especially as preservation techniques advance and the line blurs between organ donation and the potential commodification of body parts. As the global organ preservation market continues to expand, navigating these ethical challenges will require ongoing dialogue, transparency, and a commitment to uphold the principles of beneficence, non-maleficence, and justice in the pursuit of improving patient outcomes.

Opportunities:

• Emerging markets
• Development of novel preservation solutions
• Collaborations and partnerships
• Focus on personalized medicine

• Growing medical tourism industry: The global organ preservation market is experiencing significant growth, largely driven by advancements in medical technology and an increasing demand for organ transplantation procedures worldwide. Organ preservation solutions play a crucial role in maintaining the viability of organs during transportation and storage, ensuring their suitability for transplantation. With rising incidences of organ failure and a growing aging population, the need for organ transplantation is escalating, further fueling the demand for organ preservation techniques.

  The booming medical tourism industry is also contributing to the expansion of the organ preservation market. Many patients from developed countries travel to emerging economies for affordable medical treatments, including organ transplantation procedures. This trend is particularly prevalent in countries where healthcare costs are relatively lower, coupled with high-quality medical infrastructure and skilled healthcare professionals. As a result, the demand for organ preservation solutions is expected to surge in regions popular for medical tourism, driving market growth and innovation in organ preservation technologies. The combination of technological advancements, increasing demand for organ transplantation, and the flourishing medical tourism sector is propelling the growth of the global organ preservation market.

Key players in Global Organ Preservation Market include:

• XVIVO Perfusion AB
• Organ Recovery Systems, Inc
• Preservation Solutions, Inc
• TransMedics, Inc
• Waters Medical Systems LLC
• OrganOx Limited
• Bridge to Life Ltd
• OrganAssist BV
• Essential Pharmaceuticals LLC
• 21st Century Medicine Inc

In this report, the profile of each market player provides following information:

• Company Overview and Product Portfolio
• Key Developments
• Financial Overview
• Strategies
• Company SWOT Analysis